Search clinical trials for: MK-8457 100 mg

Total 1658 results

Eli Lilly and Company
CoLucid Pharmaceuticals

Completed

Three Doses of Lasmiditan (50 mg, 100 mg and 200 mg) Compared to Placebo in the Acute Treatment of Migraine (SPARTAN)

Migraine With or Without Aura

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Pharmacokinetic and Pharmacodynamic Study to Determine Blood Levels of JNJ-28431754 (Canagliflozin) in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States
Idorsia Pharmaceuticals Ltd.

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT-451840 in Healthy Subjects (Part A)

Healthy

France
Azienda Ospedaliera Universitaria Policlinico Paolo...

Completed

Elbasvir/Grazoprevir Fixed-Dose Combination for 8 Weeks in G1b Treatment-Naïve, HCV-Infected Patients (EGG-18)

Chronic HCV Hepatitis

Italy
Taichung Veterans General Hospital
Merck Sharp & Dohme LLC

Terminated

Grazoprevir/Elbasvir for Genotype 1b Chronic Hepatitis C After Liver or Kidney Transplantation

Liver Transplant Infection | Kidney Transplant Infection | Chronic Hepatitis c

Taiwan
University of California, San Francisco

Recruiting

Ocular Rosacea Biome Study (ORBS)

Antimicrobial Resistance | Ocular Rosacea

United States
National Cardiovascular Center Harapan Kita Hospital...

Completed

Low Dose Continuous Furosemide Effect on Cardiac Surgery Patients With Kidney Dysfunction

Chronic Kidney Disease | Cardiac Disease

Indonesia
Bausch Health Americas, Inc.

Withdrawn

Study to Evaluate the Safety and Efficacy of VIRAZOLE® in Hospitalized Adult Participants With Respiratory Distress Due to COVID-19

COVID19
Federal University of the Valleys of Jequitinhonha...
University of Campinas, Brazil

Completed

Valerian for Conscious Sedation in Patients Submitted to Impacted Lower Third Molars Surgery

Blood Pressure | Dental Anxiety | Heart Rate

Brazil
Sanofi

Completed

Efficacy Study of Pristinamycin Versus Amoxicillin to Treat Tonsillitis Induced by Streptococcus in Children (PRI-angine)

Tonsillitis

France
Epicentre
Médecins Sans Frontières, France; Embassy of France in Uganda; National Sleeping...

Terminated

Randomized Clinical Trial of Three Drug Combinations for Late-Stage Gambiense Human African Trypanosomiasis

Trypanosomiasis, African

Uganda
Regado Biosciences, Inc.

Completed

Safety, Tolerability and PK/PD of RB006 in a Healthy Volunteer SAD (SC101)

Healthy Volunteer

United States
Novo Nordisk A/S

Completed

A Research Study Looking at How NNC0385-0434 Tablets Work to Lower Blood Cholesterol in People With Heart Disease or a High Risk of Heart Disease

Atherosclerotic Cardiovascular Disease

Germany, Poland, United States, Netherlands, Japan, Greece, Belgium
CHC MontLégia

Active, not recruiting

Daily Monitoring of Respiratory Symptoms and Spirometry During ETI Treatment in Persons With Cystic Fibrosis.

Cystic Fibrosis

Belgium
Janssen Research & Development, LLC

Completed

Study of Safety, Efficacy of Fulranumab Adjunctive Use in OA of Hip or Knee, PAI3007

Pain | Osteoarthritis

United States, Australia, Poland, Korea, Republic of, Canada, Germany, Hungary, Spain, Czechia, Sweden, United Kingdom
Instituto Nacional de Ciencias Medicas y Nutricion...
Gilead Sciences

Not yet recruiting

Elimination of Hepatitis C Virus Among Users of Substances (EHCUS)

Hepatitis C in Substance Users
Almirall, S.A.
Allergan

Completed

Double-Blind, Placebo-Controlled Study to Evaluate 3 Doses of a Novel Tetracycline in the Treatment of Facial Acne Vulgaris

Acne Vulgaris

United States
GlaxoSmithKline

Completed

Study in Healthy Volunteers, to Evaluate the Safety, Efficacy and Dose Responses of SB-751689 (Ronacaleret)

Transplantation, Stem Cell

United States
National Cancer Institute (NCI)

Completed

Protein Phosphatase 2A Inhibitor, in Recurrent Glioblastoma

Glioma | Glioblastoma Multiforme | Giant Cell Glioblastoma | Oligodendrogliomas | Astrocytoma, Grades II, III and IV

United States
Medical University of Lublin
Pharmabest Sp. z o.o.

Completed

Effect of Lactoferrin Supplementation on Urinary Tract Infections in Infants.

Urinary Tract Infections in Children
Alvotech Swiss AG

Completed

Comparative Safety, Tolerability, Pharmacokinetic Study of AVT02 (100MG/ML) and Humira (100MG/ML) in Healthy Volunteers (ALVOPAD)

Healthy Volunteers

Australia
Birken AG
University Hospital Tuebingen

Completed

The Efficacy and Tolerability of Oleogel-S-10 in Patients With Actinic Keratoses

Actinic Keratoses

Germany, Greece
Mylan Pharmaceuticals Inc

Completed

Food Study of Sertraline Hydrochloride Tablets 100 mg and Zoloft® Tablets 100 mg

Healthy

United States
Merck Sharp & Dohme LLC
Pfizer

Completed

A Study of the Efficacy and Safety of Ertugliflozin in Participants With Type 2 Diabetes Mellitus With Stage 3 Chronic Kidney Disease Who Have Inadequate Glycemic Control on Antihyperglycemic Therapy (MK-8835-001)

Type 2 Diabetes Mellitus
BioMarin Pharmaceutical

Terminated

Phase IIb Study of PRO045 in Subjects With Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy

Belgium, Netherlands, France, United Kingdom, Italy
Bausch Health Americas, Inc.

Completed

Study to Evaluate the Safety and Efficacy of VIRAZOLE® in Hospitalized Adult Participants With Respiratory Distress Due to COVID-19

COVID19

Greece, Mexico
Yuhan Corporation

Completed

Food Effect on Pharmacokinetics of YH4808 in Healthy Male Subjects

Healthy

Korea, Republic of
Mylan Pharmaceuticals Inc

Completed

Study of Sertraline Hydrochloride Tablets 100 mg and Zoloft® Tablets 100 mg

Healthy

United States
Medical University of South Carolina

Completed

The Effect of Minocycline and N-acetylcysteine for the Treatment of Fibromyalgia

Fibromyalgia

United States
Ain Shams University

Completed

Doubling the Iron Dose to Prevent IDA in Twin Pregnant Women (IDA)

Hematologic Pregnancy Complications

Egypt
Ranbaxy Laboratories Limited

Completed

A Comparitive Bioavailability Study of Metformin Hydrochloride Liquid 500mg/ 5 mL Under Fasting Conditions and After Low and High Fat Meal

Healthy
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

Study of Peposertib in Combination With Capecitabine and RT in Rectal Cancer

Locally Advanced Rectal Cancer

United States, Spain
San Gerardo Hospital
IRCCS Policlinico S. Matteo; University of Milano Bicocca; Azienda L'ULSS 15... and other collaborators

Completed

Intraperitoneal Ropivacaine Nebulization for Pain Control After Laparoscopic Surgery

Laparoscopic Cholecystectomy

Italy
Pharmtechnology LLC
ClinPharmInvest, LLC

Not yet recruiting

Bioequivalence Study of Two Formulations of Sildenafil Tablet 100 mg in Healthy Male Volunteers Under Fasting Conditions

Bioequivalence

Russian Federation
New York State Psychiatric Institute
Clinilabs, Inc.

Recruiting

Clinical Trials of Multivalent Opioid Vaccine Components

Opioid-use Disorder

United States
MedImmune LLC
MedImmune Ltd

Completed

A Study to Evaluate the Efficacy and Safety of CAM-3001 (Drug) in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Bulgaria, Poland, Russian Federation, Estonia, Hungary, Latvia, Lithuania, Romania, Ukraine, Czechia, Japan
MedImmune LLC
AstraZeneca

Completed

A Study to Evaluate the Effectiveness of MEDI-563 in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

United States, Poland, Spain, United Kingdom, Denmark, Canada, Germany
Janssen Research & Development, LLC
Merck Sharp & Dohme LLC

Completed

An Efficacy and Safety Study of Golimumab (CNTO 148) in Participants With Moderately to Severely Active Ulcerative Colitis

Colitis, Ulcerative

United States, Canada, France, Poland, Ukraine, Germany, Israel, Bulgaria, India, Romania, Serbia, South Africa, Japan, Australia, Netherlands, Sweden, Belgium, New Zealand, Russian Federation, Czech Republic, Hungary, Austria, Denmark and more
Theratocular Biotek Co.

Recruiting

A Study to Investigate the Effect on Central Macular Thickness of Treatment With MG-O-1002 Eye Drops in Participants Aged Over 45 With Neovascular Age-related Macular Degeneration (nAMD)

Age-Related Macular Degeneration

Thailand
Takeda

Completed

Efficacy and Safety of Vedolizumab Subcutaneous (SC) as Maintenance Therapy in Crohn's Disease (CD)

Crohn's Disease

Belgium, Israel, Korea, Republic of, Netherlands, Australia, Denmark, Russian Federation, Hungary, Serbia, Bulgaria, Canada, Germany, Italy, Poland, Slovakia, Czechia, Mexico, Romania, Brazil, Estonia, United States, Bosnia and Herzegovina and more
Grifols Therapeutics LLC

Completed

A Dose Escalation and Safety Study of Plasmin (Human) In Acute Lower Extremity Native Artery or Bypass Graft Occlusion (PRIORITY)

Arterial Occlusive Diseases

United States
Tibotec Pharmaceuticals, Ireland

Completed

A Study to Determine the Antiviral Activity of TMC310911 When Administered With Ritonavir in Treatment-Naive Human Immunodeficiency Virus - Type 1 (HIV-1) Infected Patients

Human Immunodeficiency Virus Type 1

Germany
Merck Sharp & Dohme LLC

Completed

A Study of Islatravir (MK-8591) in Anti-Retroviral Therapy-Naive, Human Immunodeficiency Virus-1 Infected Participants (MK-8591-003)

HIV-1
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate Next Day Effects of MK-4305 on Driving Performance (MK-4305-035 AM1)

Insomnia

Netherlands
MediBeacon

Completed

Pharmacokinetics of MB-102 and Use of the Non-invasive Optical Renal Function Monitor (ORFM) Device in Subjects With Normal and Impaired Renal Function and a Range of Skin Color Types

Acute Kidney Injury

United States
Dong-A ST Co., Ltd.

Completed

A Clinical Trial to Investigate Safety/Tolerability and Pharmacokinetics of DA-1229_01 Compared to Co-administration of Evogliptin 5 mg and Metformin XR 1000 mg, and to Evaluate the Effect of Food on the Pharmacokinetics of DA-1229_01 in Healthy Male Volunteers

Type 2 Diabetes Mellitus

Korea, Republic of
Catherine Anne Chappell
Gilead Sciences

Recruiting

Sofosbuvir/Velpatasvir Treatment of Chronic Hepatitis C During Pregnancy (STORC)

Hepatitis C, Chronic | Pregnancy; Infection

United States, Canada
Xspray Pharma AB
QPS Bioserve India Pvt Limited

Completed

Comparative Bioavailability of XS004 (Dasatinib) Formulation G and SPRYCEL® (Dasatinib) in Healthy, Adult Subjects Under Fasting Conditions

Biological Availability

India
Janssen Research & Development, LLC

Completed

Treatment Differences Between Canagliflozin and Placebo in Insulin Secretion in Subjects With Type 2 Diabetes Mellitus (T2DM)

Diabetes Mellitus, Type 2

United States
Janssen-Cilag International NV

Completed

A Single Ascending Dose Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JNJ-42165279 in Healthy Male Participants

Healthy Volunteers | Pharmacokinetics

Belgium

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