Clinical Trials Sponsored by Middlemore Clinical Trials

Total 2331 results

Ortho Pharmaceuticals

Completed

A Double-Blind, Placebo-Controlled Study With Open-Label Follow-Up To Determine the Safety and Efficacy of r-HuEPO in AIDS Patients With Anemia Induced by Their Disease and AZT Therapy

HIV Infections | Cytopenias

United States
Janssen, LP

Completed

Protocol For the Treatment of Cryptosporidiosis in AIDS Patients With Diclazuril (R64,433)

HIV Infections | Cryptosporidiosis

United States
Lederle Laboratories

Completed

An Ascending, Single Oral Dose Pharmacokinetic Study of 3'-Deoxy-3'-Fluorothymidine (FLT) in Asymptomatic Human Immunodeficiency Virus (HIV)-Infected Subjects

HIV Infections

United States
Astra USA

Completed

An Open Study of Foscarnet Treatment of Acyclovir-Resistant Herpes Simplex Virus in Patients With the Acquired Immunodeficiency Syndrome and Other Immunodeficiencies

HIV Infections | Herpes Simplex

United States
Glaxo Wellcome

Completed

A Pilot Study of 566C80 for the Salvage Treatment of Toxoplasmic Encephalitis in Patients Infected With the Human Immunodeficiency Virus (HIV) Who Have Failed or Are Intolerant of Pyrimethamine-Sulfadiazine

HIV Infections | Toxoplasmosis, Cerebral

United States, Canada
Glaxo Wellcome

Completed

A Study of Azidothymidine (AZT) in the Treatment of HIV Infection in Patients Receiving a Bone Marrow Transplant

HIV Infections | Lymphoma, Non-Hodgkin

United States
Glaxo Wellcome

Completed

A Study to Compare the Safety and Effectiveness of Two Dosing Schedules of Lamivudine in Combination With Two Other Anti-HIV Drugs

HIV Infections

United States
Glaxo Wellcome

Completed

The Efficacy and Safety of Retrovir in Patients Infected With HIV Who Are Asymptomatic (CDC Group II) or Have Persistent Generalized Lymphadenopathy (CDC Group III)

HIV Infections | Lymphatic Disease

United States
Centaur Pharmaceuticals

Unknown

Safety and Effectiveness of Giving CPI-1189 to HIV-Infected Patients With AIDS Dementia

HIV Infections

United States
Gilead Sciences

Completed

Tenofovir Disoproxil Fumarate (TDF) in HIV-1 Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States
Daiichi Pharmaceuticals

Completed

A Phase I Trial of Tecogalan Sodium ( DS-4152 ) Administered as an Infusion Weekly x 4

HIV Infections | Sarcoma, Kaposi

United States
Gilead Sciences

Completed

The Safety and Effectiveness of Cidofovir in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States, United Kingdom
Glaxo Wellcome

Unknown

Comparison of GW433908 and Nelfinavir in HIV Patients Who Have Not Had Antiretroviral Therapy

HIV Infections

United States
U.S. Bioscience

Completed

A Compassionate Treatment Protocol for the Use of Trimetrexate Glucuronate (Neutrexin) With Leucovorin Protection for European Adult Patients (>= 13 Years Old) With Pneumocystis Carinii Pneumonia

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Triangle Pharmaceuticals

Completed

A Randomized, Double-Blind Study of MKC-442 Combined With Viracept in Patients Who Are Epivir + Retrovir Experienced and Are Protease Inhibitor- and Non-Nucleoside Reverse Transcriptase Inhibitor-Naive

HIV Infections

United States
Unimed Pharmaceuticals

Completed

A Study of Nitazoxanide in the Treatment of AIDS-Related Diarrhea

HIV Infections

United States
Glaxo Wellcome

Unknown

Safety and Effectiveness of Three Anti-HIV Drugs Combined in One Pill (Trizivir)

HIV Infections

United States
Genelabs Technologies

Completed

A Randomized Phase II Efficacy, Activity and Safety Study of GLQ223 Alone and in Combination With Zidovudine in Symptomatic HIV-Infected Patients Without Prior Treatment With GLQ223 or Trichosanthin

HIV Infections

United States
Glaxo Wellcome

Completed

A Study to Compare the Efficacy and Safety of Valacyclovir Hydrochloride ( 256U87 ) Versus Acyclovir in the Treatment of Recurrent Anogenital Herpes Infections in HIV Infected Patients

HIV Infections | Herpes Simplex

United States
Ortho Pharmaceuticals

Completed

A Double-Blind, Placebo-Controlled Study With Open-Label Follow-Up To Determine the Safety and Efficacy of r-HuEPO in AIDS and Advanced ARC Patients With Anemia

HIV Infections | Cytopenias

United States
Schering-Plough

Completed

Phase III Ganciclovir +/- rGM-CSF for AIDS-Related CMV Retinitis

HIV Infections | Cytomegalovirus Retinitis

United States
Janssen Pharmaceuticals

Completed

Randomized, Controlled, Double-Blind Study of Itraconazole Oral Solution Versus Fluconazole Tablets for the Treatment of Esophageal Candidiasis.

HIV Infections | Candidiasis, Esophageal

United States
Gilead Sciences

Completed

Cidofovir as a Treatment for Herpes Simplex in Patients With AIDS

HIV Infections | Herpes Simplex

United States
Lederle Laboratories

Completed

Phase II Study of Intravenous Novantrone(R) in the Treatment of AIDS Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States
Janssen, LP

Completed

A 28-Day Study of Diclazuril in the Treatment of Cryptosporidiosis in Patients With AIDS

HIV Infections | Cryptosporidiosis

United States
Janssen, LP

Completed

A Study of Treatments for Fungal Infections of the Mouth and Throat in HIV-Infected Patients Who Have Had Success With Itraconazole But Not With Fluconazole

HIV Infections | Candidiasis, Oral

United States
Dupont Merck

Completed

A Study of Three Different Anti-HIV Drug Combinations in HIV-Infected Patients

HIV Infections

United States, Puerto Rico
Triangle Pharmaceuticals

Completed

A Study of MKC-442 in Combination With Other Anti-HIV Drugs

HIV Infections

United States
Agouron Pharmaceuticals

Completed

Safety and Effectiveness of Treating HIV-Positive Patients With an HIV Vaccine (Remune)

HIV Infections

United States
Celgene Corporation

Completed

Compassionate Use Study of Two Dose Levels of Thalidomide in Adults With HIV Wasting Syndrome

HIV Infections | HIV Wasting Syndrome

United States
Gilead Sciences

Completed

A Phase I/II Study of the Safety and Efficacy of Topical 1-(S)-(3-Hydroxy-2-Phosphonylmethoxypropyl)Cytosine Dihydrate (Cidofovir; HPMPC) in the Treatment of Refractory Mucocutaneous Herpes Simplex Disease in Patients With AIDS

HIV Infections | Herpes Simplex

United States, Canada
Chiron Corporation

Completed

Safety and Efficacy of Polyethylene Glycolated IL-2 (PEG IL-2) Plus Zidovudine or Dideoxyinosine in HIV Positive, Asymptomatic and Symptomatic Individuals

HIV Infections

United States
Daiichi Pharmaceuticals

Completed

A Phase I Trial of Tecogalan Sodium ( DS-4152 ) Administered as an Infusion Twice Weekly for 21 Days.

HIV Infections | Sarcoma, Kaposi

United States
Gilead Sciences

Completed

A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Adefovir Dipivoxil When Added to Standard Antiretroviral Therapy for the Treatment of HIV-Infected Patients With CD4 Cell Counts >= 200/mm3

HIV Infections

United States
Agouron Pharmaceuticals

Completed

A Study of Viracept in AIDS Patients With Cytomegalovirus Retinitis

HIV Infections | Cytomegalovirus Retinitis

United States
Glaxo Wellcome

Completed

A Comparison of Two Multi-Drug Therapies in HIV-Infected Patients Who Have Never Received Anti-HIV Treatment

HIV Infections

United States
Lederle Laboratories

Completed

A Multi-Center, Open-Label, Ascending, Multiple Oral Dose, Safety, Tolerance and Pharmacokinetic Study of 3'-Deoxy-3'-Fluorothymidine (FLT) in Patients With Acquired Immune Deficiency Syndrome (AIDS) or AIDS-Related Complex (ARC)

HIV Infections

United States
Glaxo Wellcome

Completed

The Safety and Effectiveness of Retrovir in HIV-Infected Patients Who Have Problems Related to the Nervous System

HIV Infections

United States
Gilead Sciences

Completed

The Safety and Effectiveness of Bis-POM PMEA in HIV-Infected Patients

HIV Infections

United States
Triangle Pharmaceuticals

Suspended

A Comparison of Emtricitabine and Abacavir Used in a Three-Drug Combination in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States
Gilead Sciences

Unknown

The Safety and Effectiveness of PMPA Prodrug in HIV-Infected Patients

HIV Infections

United States
Glaxo Wellcome

Completed

Safety and Effectiveness of a Combination Anti-HIV Drug Treatment

HIV Infections

United States
Triangle Pharmaceuticals

Completed

Comparing FTC and Lamivudine in HIV-Infected Patients on a Stable Anti-HIV Drug Combination

HIV Infections

United States
Boehringer Ingelheim

Completed

The Safety and Effectiveness of Nevirapine Plus Lamivudine Plus Other Anti-HIV Drugs

HIV Infections

United States
Janssen, LP

Completed

A Randomized, Open, Comparative Multicenter Study of Initial Treatment With Intravenous Itraconazole Versus Amphotericin B Followed by Consolidation Treatment With Itraconazole Capsules in Patients With Blastomycosis or Histoplasmosis

HIV Infections | Histoplasmosis | Blastomycosis

United States
Triangle Pharmaceuticals

Completed

A Study of MKC-442 in HIV-Positive Patients

HIV Infections
Glaxo Wellcome

Completed

The Safety and Effectiveness of 524W91

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of 1592U89 in Combination With Protease Inhibitors in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States
Gilead Sciences

Completed

Safety and Effectiveness of Giving Adefovir (Preveon) Plus Other Anti-HIV Drugs to HIV-Infected Patients Who Have Not Responded to Other Anti-HIV Drug Combinations

HIV Infections

United States
Boehringer Ingelheim

Completed

The Safety and Effectiveness of Nevirapine Plus Nelfinavir in HIV-1 Infected Patients Who Have Taken Stavudine

HIV Infections

United States

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