Clinical Trials Sponsored by Semprus BioSciences, Inc

Total 726 results

UCB BIOSCIENCES, Inc.
Zogenix, Inc.

Active, not recruiting

An Open-Label Study of Continuation Treatment With Combination Pyrimidine Nucleosides in Patients With TK2 Deficiency (Continuation)

Thymidine Kinase 2 Deficiency

United States, Israel, Spain
A2 Biotherapeutics Inc.
Tempus AI

Recruiting

A Study to Evaluate the Safety and Efficacy of A2B694, a Logic-gated CAR T, in Subjects With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression (EVEREST-2)

Cancer | Colorectal Cancer | Ovarian Neoplasms | Ovarian Cancer | NSCLC | Lung Cancer | Rectal Cancer | Non Small Cell Lung Cancer | Mesothelioma | Mesothelioma, Malignant | Colon Cancer | Pancreas Cancer | Colorectal Adenocarcinoma | Solid Tumor, Adult | CRC | Pancreatic Neoplasm | Ovary Cancer | NSCLC, Recurrent | Non-Small Cell... and other conditions

United States
Phylos Bioscience, Inc.
People Science, Inc.

Recruiting

A Direct-to-Consumer Study Investigating the Effect of Specific Cannabinoid Products on Motivation, Energy Level, Focus, and Appetite in Healthy Adults

Motivation

United States
Mirati Therapeutics Inc.
Aadi Bioscience, Inc.

Active, not recruiting

Adagrasib in Combination With Nab-Sirolimus in Patients With Advanced Solid Tumors and Non-Small Cell Lung Cancer With a KRAS G12C Mutation (KRYSTAL -19)

NSCLC | Metastatic Cancer | Advanced Cancer | Solid Tumor, Adult | Malignant Neoplastic Disease

United States
CAGE Bio Inc.
BioScience Laboratories, Inc.

Completed

Clinical Evaluation of the Residual Antimicrobial Activity

Bacterial Overgrowth

United States
IGM Biosciences, Inc.
ADC Therapeutics S.A.

Active, not recruiting

A Study of Imvotamab Monotherapy and in Combination in Subjects With Relapsed/Refractory Non-Hodgkin Lymphoma

Follicular Lymphoma | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Non-Hodgkin Lymphoma | DLBCL

United States, Korea, Republic of, Spain, France, Australia, Czechia, Italy
University of Arizona
Senhwa Biosciences, Inc.

Terminated

Silmitasertib (CX-4945) in Patients With Severe Coronavirus Disease 2019 (COVID-19) (CX4945)

Coronavirus

United States
Emalex Biosciences Inc.
Syneos Health; Nuventra

Completed

Drug-Drug Interaction Study to Evaluate the Effect of Inhibition of UGTs on the PK of Ecopipam and Its Active Metabolite

Drug Interaction

United States
Escalier Biosciences B.V.
Innovaderm Research Inc.

Completed

A Study to Evaluate the Safety, Pharmacokinetics, and Efficacy of Topical ESR-114 in Subjects With Plaque Psoriasis

Psoriatic Plaque

United States, Canada
Aptose Biosciences Inc.
Ohio State University

Completed

Combination of GTI-2040 and Cytarabine in the Treatment of Refractory and Relapsed Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia

United States
Altesa Biosciences, Inc.
Virtus Respiratory Research

Recruiting

RCT of Vapendavir in Patients With COPD and Human Rhinovirus/Enterovirus Upper Respiratory Infection

Infections | Virus Diseases | Respiratory Tract Infections | Respiratory Tract Diseases | Lung Diseases | Pulmonary Disease, Chronic Obstructive | Enterovirus Infections | Copd | Pulmonary Disease | Respiratory Disease | Respiratory Complication | Upper Respiratory Tract Infections | Respiratory Viral Infection | ... and other conditions

United Kingdom
Massachusetts General Hospital
Vedanta Biosciences, Inc.

Recruiting

VE416 for Treatment of Food Allergy

Peanut Allergy

United States
Brii Biosciences Limited
Vir Biotechnology, Inc.

Active, not recruiting

Investigate the Efficacy and Safety of BRII-835 (VIR-2218) and PEG-IFNα Combination Therapy in Chronic HBV Patients

Chronic Hepatitis B Virus Infection

Singapore, Thailand, Australia, China, Korea, Republic of
Chris Recknor, MD

Completed

Evaluating Safety, Pharmacokinetics and Clinical Benefit of Silmitasertib (CX-4945) in Subjects With Moderate COVID-19

Covid19

United States
Emalex Biosciences Inc.
Syneos Health; Nuventra

Terminated

Drug-Drug Interaction Study to Evaluate the Effects of Ecopipam on the Pharmacokinetics of Multiple Substrates

Drug-Interactions

United States
Daiichi Sankyo, Inc.
Ambit Biosciences Corporation

Completed

Open Label Study to Evaluate Safety and Efficacy of 2 Doses of Quizartinib in Patients With Relapsed or Refractory Acute Myeloid Leukemia

Leukemia, Myeloid, Acute

United States, France, Italy, United Kingdom
Daiichi Sankyo, Inc.
Ambit Biosciences Corporation

Completed

A Study of AC220 Given After Transplant in Subjects With Acute Myeloid Leukemia (AML)

Leukemia, Myeloid, Acute

United States
Daiichi Sankyo, Inc.
Ambit Biosciences Corporation

Completed

A Study to Assess AC220 Given in Combination With Induction and Consolidation Therapy in Newly Diagnosed Acute Myeloid Leukemia (AML)

Leukemia, Myeloid, Acute

United States
Avelas Biosciences, Inc.
Clinipace Worldwide; RRD International, Inc.

Completed

Study of AVB-620 in Women With Primary, Nonrecurrent Breast Cancer Undergoing Surgery

Stage I Breast Cancer | Stage II Breast Cancer | Carcinoma, Ductal, Breast | Breast Cancer Female | Stage III Breast Cancer | Carcinoma Breast | Primary Invasive Malignant Neoplasm of Female Breast

United States
NexMed (U.S.A.), Inc. (subsidiary of Apricus Biosciences...

Completed

Study of Acute Peripheral Vascular Effects, Safety and Tolerability in Subjects With Raynaud's Phenomenon Secondary to Systemic Sclerosis

Raynaud's Phenomenon Secondary to Systemic Sclerosis

United States
Ainos, Inc. (f/k/a Amarillo Biosciences Inc.

Completed

Treatment of Oral Warts in HIV+ Patients

HIV Infections | Papillomatosis

United States
NexMed (U.S.A.), Inc. (subsidiary of Apricus Biosciences...

Completed

Safety and Pharmacokinetics of Terbinafine Hydrogen Chloride (HCl) Nail Lacquer in Patients With Onychomycosis

Onychomycosis/Onycholysis and Tinea Pedis

United States
Vedanta Biosciences, Inc.
Bristol-Myers Squibb

Completed

Study of VE800 and Nivolumab in Patients With Selected Types of Advanced or Metastatic Cancer (ConsortiumIO)

Melanoma | Gastric Cancer | Colorectal Cancer | Metastatic Cancer | Gastroesophageal Junction Adenocarcinoma

United States
UCB BIOSCIENCES, Inc.
Parexel

Completed

Open-label, Bioequivalence Study of Certolizumab Pegol 200 mg Solution Injected Either by a Prefilled Syringe (Reference) or by an E-Device (Test) in Healthy Subjects

Healthy

United States
Meridian Bioscience, Inc.
Conatus Pharmaceuticals

Completed

Companion Protocol for Methacetin Breath Test (MBT) in Conatus Protocol IDN-6556-14

Cirrhosis | Portal Hypertension | NASH - Nonalcoholic Steatohepatitis

France
Forest Laboratories
Cypress Bioscience, Inc.

Terminated

Long-Term Safety and Efficacy Study of Milnacipran in Pediatric Patients With Primary Fibromyalgia (MyFi)

Primary Fibromyalgia

United States
Forest Laboratories
Cypress Bioscience, Inc.

Completed

Discontinuation Study of the Durability of Effect of Milnacipran for the Treatment of Fibromyalgia

Fibromyalgia

United States
NexMed (U.S.A.), Inc. (subsidiary of Apricus Biosciences...

Unknown

Safety and Efficacy Study of Oral Fispemifene for the Treatment of Sexual Dysfunction in Hypogonadal Men

Sexual Dysfunction | Erectile Dysfunction | Secondary Hypogonadism

United States
BioNumerik Pharmaceuticals, Inc.
Crown Bioscience

Completed

Karenitecin Versus Topotecan in Patients With Advanced Epithelial Ovarian Cancer

Ovarian Cancer

Poland, Russian Federation, Romania, Hungary, Lithuania
BioNumerik Pharmaceuticals, Inc.
Crown Bioscience

Completed

Study of Karenitecin (BNP1350) to Treat Malignant Melanoma

Melanoma | Neoplasm

United States
Perle Bioscience, Inc.
Syreon Corporation

Withdrawn

The Insulin Independence Trial (IIT) Evaluating the Safety and Efficacy of Oral Cyclosporine and Oral Omeprazole for Insulin Independence Among Recent Onset Type 1 Diabetes Patients (IIT)

Type 1 Diabetes
Altor BioScience
Genentech, Inc.; Tanox

Completed

Effects of TNX-832 (Sunol cH36) in Subjects With Acute Lung Injury/Acute Respiratory Distress Syndrome

Sepsis | Acute Respiratory Distress Syndrome | Acute Lung Injury

United States, Canada
Forest Laboratories
Cypress Bioscience, Inc.

Completed

Study of Milnacipran for the Treatment of Fibromyalgia

Fibromyalgia

United States
Forest Laboratories
Cypress Bioscience, Inc.

Completed

A Study Of Milnacipran In Patients With Fibromyalgia: Effects On 24 Hour Ambulatory Blood Pressure Monitoring

Fibromyalgia

United States
Meridian Bioscience, Inc.
Conatus Pharmaceuticals

Terminated

Companion Protocol for Methacetin Breath Test (MBT) in Conatus Protocol IDN-6556-17

Decompensated Cirrhosis

United States
INVO Bioscience, Inc.
Ferring Pharmaceuticals

Suspended

Assessment of the INVOcell Intravaginal Culture System

Infertility

United States
BioNumerik Pharmaceuticals, Inc.
Crown Bioscience

Completed

Trial of Oral Karenitecin in Patients With Solid Tumors and Lung Cancer

Carcinoma | Carcinoma, Non-Small-Cell Lung

United States
BioNumerik Pharmaceuticals, Inc.
Crown Bioscience

Completed

Study of Karenitecin (BNP1350) in Patients With Brain Tumors

Brain Neoplasms | Brain Tumors | Malignant Neoplasms, Brain

United States
Forest Laboratories
Cypress Bioscience, Inc.

Terminated

Safety and Efficacy of Milnacipran in Pediatric Patients With Primary Fibromyalgia (MyFi)

Primary Fibromyalgia

United States
Forest Laboratories
Cypress Bioscience, Inc.

Completed

Study of Milnacipran in Patients With Inadequate Response to Duloxetine for the Treatment of Fibromyalgia

Fibromyalgia

United States
Ainos, Inc. (f/k/a Amarillo Biosciences Inc.
CytoPharm, Inc.

Completed

Interferon-alpha Lozenges for Prevention of Relapse in Hepatitis C

Hepatitis C, Chronic

Taiwan
Ainos, Inc. (f/k/a Amarillo Biosciences Inc.
CytoPharm, Inc.

Completed

Interferon Alpha Lozenges Plus Oseltamivir for Influenza Treatment

Influenza A Virus Infection

Taiwan
Brii Biosciences Limited
VBI Vaccines Inc.; Vir Biotechnology, Inc.

Completed

Study to Investigate the Safety and Efficacy of BRII-835 and BRII-179 Combination Therapy Treating Chronic Hepatitis B Virus (HBV) Infection

Hepatitis B, Chronic

Australia, China, Korea, Republic of, New Zealand, Singapore, Thailand
Arcturus Therapeutics, Inc.
Novotech (Australia) Pty Limited; Seqirus

Recruiting

Safety and Immunogenicity First-in-human Dose-ranging Study of Self-Amplifying RNA Seasonal Influenza Vaccine in Adults

Influenza, Human

Australia
Arcturus Therapeutics, Inc.
Novotech (Australia) Pty Limited; Seqirus

Active, not recruiting

Immunogenicity and Safety Study of Self-amplifying mRNA COVID-19 Vaccine Administered With Influenza Vaccines in Adults

COVID-19

Australia, Costa Rica, Honduras, Philippines
Lawson Health Research Institute
Greenstone Biosciences, Inc.

Recruiting

iPSC Biobank of Biomarkers Diversity in Cardiovascular Disease (INFERENCE)

Cardiovascular Diseases | Heart Failure | Cardiomyopathies | Congenital Heart Disease | Cerebrovascular Accident | Arrythmia | Cardiometabolic Syndrome

Canada
Evopoint Biosciences Inc.
Merck Sharp & Dohme LLC

Recruiting

Study of XNW5004 Tablet in Combination With KEYTRUDA® (Pembrolizumab) in Subjects With Advanced Solid Tumors Who Failed Standard Treatments (KEYNOTE F19)

Carcinoma | Cervical Cancer | Prostate Cancer | Squamous Cell Carcinoma of Head and Neck | Non-small Cell Lung Cancer | Small-cell Lung Cancer | Urothelial Carcinoma | Other Solid Tumors

China
Seoul National University Hospital
Ensol Biosciences, Inc.

Completed

To Evaluate the Safety, Tolerability, and Pharmacokinetics After Subcutaneous Administration of C1K in Healthy Subjects

Healthy Subjects

Korea, Republic of
Quadriga Biosciences, Inc.
Novotech (Australia) Pty Limited

Completed

Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S

Melanoma | Sarcoma | Kidney Cancer | Cervical Cancer | Breast Cancer | Head and Neck Cancer | Astrocytoma | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Thymic Carcinoma | Lung Cancer | Prostate Cancer | Brain Cancer | Cholangiocarcinoma | Bladder Cancer | Liver Cancer | Brain Metastases | Tongue Cancer | Esophagus... and other conditions

Australia
UCB BIOSCIENCES, Inc.
R-Pharm

Terminated

The Long-term Safety and Efficacy of CDP6038 (Olokizumab) With Active Rheumatoid Arthritis

Rheumatoid Arthritis

Japan, Korea, Republic of, Taiwan

Clinical Trials Sponsored by Semprus BioSciences, Inc

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Zambia

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Rare Diseases

Drug Interventions

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