Clinical Trials Sponsored by Technological Centre of Nutrition and Health

Total 5299 results

National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Ibrutinib, Fludarabine, and Pembrolizumab in High-Risk or Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Leukemia, Lymphocytic, Chronic, B-Cell | Chronic Lymphocytic Leukemia | Leukemia, Chronic Lymphatic | B-Cell Chronic Lymphocytic Leukemia | Leukemia, Lymphocytic, Chronic | B-Lymphocytic Leukemia, Chronic | Leukemia, Chronic Lymphocytic, B-Cell | Lymphocytic Leukemia, Chronic, B Cell | Lymphocytic Leukemia...

United States
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Treatment of Refractory Diamond-Blackfan Anemia With Eltrombopag

Anemia, Diamond-Blackfan

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow

Myeloproliferative Disorders | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Response to the SHINGRIX Varicella Zoster Virus (VZV) Vaccine in Chronic Lymphocytic Leukemia (CLL) and CLL Treated With Bruton's Tyrosine Kinase Inhibitor (BTK-I)

Chronic Lymphocytic Leukemia (CLL) | Small Lymphocytic Lymphoma (SLL) | Safety and Tolerability | Compare SHINGRIX Vaccine Response Rates

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Early Diagnosis of Sickle Acute Chest Syndrome Using a Combination of Plasma Bimarkers and Chest Imaging

Sickle Cell Disease (SCD)

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Extended Dosing With Eltrombopag for Severe Aplastic Anemia

Severe Aplastic Anemia (SAA)

United States
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Effect of Chronic Inflammation on Myocardial Perfusion and Function

Psoriasis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

A Phase II Study Using Ibrutinib and Short-Course Fludarabine in Treatment-Naive CLL

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Eltrombopag for Moderate Aplastic Anemia

Moderate Aplastic Anemia | Unilineage Bone Marrow Failure Disorders

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Pembrolizumab and Decitabine for Refractory or Relapsed Acute Myeloid Leukemia

Relapsed Acute Myeloid Leukemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Etidronate for Arterial Calcifications Due to Deficiency in CD73 (ACDC)

Arterial Calcification | CD73 Deficiency

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

RNA Sequencing in the Framingham Heart Study Third Generation Cohort Exam 2

Hypertension | Cardiovascular Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Role of Toxins in Lung Infections Caused by Pseudomonas Aeruginosa

Cystic Fibrosis | Pseudomonas Infection

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Clinical Outcomes and Molecular Phenotypes in Smokers With Parenchymal Lung Disease

Pulmonary Fibrosis | Lung Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Dexamethasone to Prevent Oral Chronic Graft-versus-Host Disease

Graft vs Host Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Stem Cell Transplantation for Metastatic Solid Tumors

Neoplasm Metastasis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Identification of Genes Expressed in Atherosclerotic Plaque

Atherosclerosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effect of High Levels of Oxygen and Smoking on the Lungs in Human Volunteers

Healthy Volunteers

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Peptide Vaccinations to Treat Patients With Low-Risk Myeloid Cancers

Acute Myeloid Leukemia (AML) | Myelodysplastic Syndrome (MDS) | Chronic Myeloid Leukemia (CML)

United States
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

A Study to Determine Whether Therapy With Daclizumab Will Benefit Patients With Bone Marrow Failure

Aplastic Anemia | Pure Red Cell Aplasia | Diamond Blackfan Anemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

The Role of Bacteria and Genetic Variations in Cystic Fibrosis

Cystic Fibrosis | Psuedomas Infection

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Screening for Subjects to Participate in Studies of Blood Disorders

Sickle Cell Disease | Bone Marrow Transplant | G-CSF

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni Syndrome

Cancer | Muscle Weakness | Skin Fibroblasts

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Mismatched Donor Lymphocyte Infusions for Relapsed Disease Following Allogeneic Stem Cell Transplantation

Leukemia, Myeloid, Acute | Leukemia, Lymphoblastic, Acute | Leukemia, Myelocytic, Chronic

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Pilot Study of the Thrombopoietin-Receptor Agonist Eltrombopag in Refractory Aplastic Anemia Patients

Thrombocytopenia | Anemia, Aplastic | Anemia, Hypoplastic

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Evaluation, Treatment, and Training for Patients With Blood Disorders

Hematologic Diseases

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Collection of Blood and Bone Marrow From Healthy Volunteers and Patients for Research Purposes

Bone Marrow Diseases | Healthy Volunteers

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cyclosporine Inhalation Solution (CIS) in Lung Transplant and Hematopoietic Stem Cell Transplant Recipients for the Treatment of Bronchiolitis Obliterans Syndrome

Bronchiolitis Obliterans | Graft vs Host Disease | Constrictive Bronchiolitis | Bronchiolitis, Exudative | Bronchiolitis, Proliferative

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cytokine Gene Polymorphisms in Bone Marrow Failure

Bone Marrow Diseases

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effect of Fish Oil Enriched In Omega-11 Fatty Acid On Lipoprotein Metabolism In Adults

Proteomics | Lipoprotein Metabolism | PCSK9

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Alemtuzumab to Treat Severe Aplastic Anemia

Severe Aplastic Anemia, Refractory | Severe Aplastic Anemia, Relapse

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Telomere Repair Gene Mutation in Inflammatory Bowel Disease

Inflammatory Bowel Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Ultra Low Dose Interleukin-2 in Healthy Volunteers

Hematologic Diseases

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cell Selection for Bone Marrow Transplants to Prevent Graft-Versus-Host-Disease

Graft vs Host Disease | Hematologic Neoplasm

United States
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Phase I/II Trial of Early Infusion of Rapidly-generated Multivirus Specific T Cells (MVST) to Prevent Post Transplant Viral Infections

Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | MDS (Myelodysplastic Syndrome) | CML (Chronic Myelogenous Leukemia) | AML (Acute Myelogenous Leukemia)

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Worksite Wellness Interventions on Vascular Function, Insulin Sensitivity and High-Density Lipoprotein in Overweight or Obese Women

Hypertension | Obesity | Diabetes Mellitus | Atherosclerosis | Dyslipidemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Pulmonary Hypertension, Hypoxia and Sickle Cell Disease

Sickle Cell Anemia | Pulmonary Hypertension | Cerebrovascular Disease | Chuvash Polycythemia

United States, Russian Federation
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Prospective International Study of Coronary Subtraction Using 320 Detector Row CT (CorSub)

Coronary Artery Disease

United States, Denmark
National Heart, Lung, and Blood Institute (NHLBI)

Completed

EW-A-401 to Treat Intermittent Claudication

Arteriosclerosis | Intermittent Claudication

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Biomarkers for Personalized Early Assessment of Response During Salvage Chemotherapy in People With Relapsed or Refractory Acute Myeloid Leukemia (PEARL15)

Acute Myeloid Leukemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Study to Evaluate the Effect of Nicotinamide Riboside on Immunity

Coronary Artery Disease | Diabetes | Atherosclerosis

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cardiac MRI for Patients Enrolled in INFUSE-AMI

Coronary Artery Disease | Myocardial Fibrosis | Acute Myocardial Infarction | Myocardial Edema | Gadolinium

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Gardasil Vaccination in Post Stem Cell Transplant Patients

Stem Cell Transplant | Immunogenicity | Gardasil Vaccine

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Assessment of Algorithm-Based Hydroxyurea Dosing on Fetal Hemoglobin Response, Acute Complications, and Organ Function in People With Sickle Cell Disease

Sickle Cell Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Evaluation of Toxicity From Stem Cell Transplant

Hemolysis | Organ Dysfunction

United States
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Early Treatment of Acute Graft Versus Host Disease With Bone Marrow-Derived Mesenchymal Stem Cells and Corticosteroids

Graft-Versus-Host Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Topical Sodium Nitrite for Chronic Leg Ulcers in Adult Patients With Blood Disorders

Sickle Cell Disease | Sickle Cell Anemia | Chronic Hemolytic Disorders

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Rosuvastatin on the Immune System in Healthy Volunteers With Normal Cholesterol

Healthy Volunteers | Statins | Immune Modulation

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Heart Function and Exercise Capacity in Patients With Hypertrophic Cardiomyopathy

Myocardial Infarction | Ischemic Heart Disease | Angina, Unstable

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

The Role of Cyclosporine in Blood Cell Transplants With T-Cell Add-Back for Blood Cancers

Multiple Myeloma | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | Graft vs Host Disease | Hematologic Neoplasm

United States

Clinical Trials Sponsored by Technological Centre of Nutrition and Health

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