Clinical Trials Sponsored by The Royal Orthopaedic Hospital NHS Trust

Total 700 results

Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; National Osteoporosis Society; Orthopaedic Research UK

Completed

The Effects of Obesity on Bone Structure and Strength

Obesity | Osteoporosis

United Kingdom
University of Oxford
London School of Hygiene and Tropical Medicine; The Leeds Teaching Hospitals... and other collaborators

Completed

Temporal Artery Biopsy vs ULtrasound in Diagnosis of GCA (TABUL) (TABUL)

Giant Cell Arteritis

Ireland, United Kingdom, Germany, Norway, Portugal
University of Cambridge
University College London Hospitals; The Leeds Teaching Hospitals NHS Trust; Cambridge...

Completed

Closing the Loop in Children and Adolescents With Type 1 Diabetes in the Home Setting (APCam08)

Glucose Metabolism Disorders | Autoimmune Diseases | Diabetes Mellitus | Endocrine System Diseases | Diabetes Mellitus, Type 1

United Kingdom
Barts & The London NHS Trust
Belfast Health and Social Care Trust; University Hospitals, Leicester; Cardiff... and other collaborators

Completed

Pre-operative Risk Assessment of Surgical Site Infection After Cardiac Surgery

Cardiac Surgery | Surgical Site Infection | Risk Assessment

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
The Leeds Teaching Hospitals NHS Trust; Versus Arthritis; Serac Healthcare

Not yet recruiting

Scintigraphy for Prediction In Rheumatoid Intentional Therapy Tapering (SPIRITT)

Rheumatoid Arthritis
Hull University Teaching Hospitals NHS Trust
Barts & The London NHS Trust; Cardiff and Vale University Health Board

Recruiting

Machine Learning in Quantitative Stress Echocardiography (MLQSE)

Cardiovascular Diseases | Ischaemic Heart Disease

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
GlaxoSmithKline; University of Cambridge; Royal Brompton & Harefield NHS Foundation... and other collaborators

Completed

Losmapimod in Chronic Obstructive Pulmonary Disease Patients Stratified by Fibrinogen. (EVOLUTION)

Chronic Obstructive Pulmonary Disease

United Kingdom
Queen Margaret University
King's College Hospital NHS Trust; Sheffield Hallam University; University Hospital... and other collaborators

Recruiting

Development and Testing of the Kidney BEAM-KIDS Digital Platform for Children After Kidney Transplantation (BEAM-KIDs)

Kidney Transplantation

United Kingdom
University of Liverpool
Imperial College London; Royal Liverpool University Hospital; University of Surrey and other collaborators

Unknown

The Effect of Exercise Intervention on Insulin Resistance in Non-alcoholic Fatty Liver Disease (NAFLD)

Non Alcoholic Fatty Liver Disease

United Kingdom
Intensive Care National Audit & Research Centre
University of Oxford; Guy's and St Thomas' NHS Foundation Trust; University of... and other collaborators

Unknown

Renal Replacement Anticoagulant Management (RRAM)

Critical Illness

United Kingdom
University Hospital Birmingham
Royal Free Hospital NHS Foundation Trust; University of Edinburgh; University...

Unknown

Comparing the Effects of Spironolactone With Chlortalidone on LV Mass in Patients With CKD (SPIRO-CKD)

Renal Insufficiency, Chronic | Cardio-Renal Syndrome

United Kingdom
Liverpool John Moores University
Liverpool University Hospitals NHS Foundation Trust; Royal Liverpool University... and other collaborators

Active, not recruiting

Can Brisk Walking Combined With Ingestion of a Lipid-lowering Drug Improve Fat Metabolism in Muscle?

Pre Diabetes

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
Society for Endocrinology; The Clinical Endocrinology Trust

Completed

Study of UK Adults With Congenital Adrenal Hyperplasia. (CaHASE)

Congenital Adrenal Hyperplasia

United Kingdom
University of Southampton
University Hospital Southampton NHS Foundation Trust; National Institute for... and other collaborators

Completed

Development and Pilot Evaluation of a Web-supported Programme of Constraint Induced Therapy Following Stroke (LifeCIT)

Stroke

United Kingdom
University College, London
Medical Research Council; Royal Free Hospital NHS Foundation Trust; ViiV Healthcare

Completed

Adding MAraViroc &/or METformin for Hepatic Steatosis in People Living With HIV (MAVMET)

Hepatic Steatosis | HIV-1-infection

United Kingdom
The Leeds Teaching Hospitals NHS Trust
University of Leeds; 4DPath

Not yet recruiting

CLinical Evaluation Of a comPuter Algorithm To Report BreAst cAncers (CLEOPATRAA) (CLEOPATRAA)

Breast Cancer

United Kingdom
The Leeds Teaching Hospitals NHS Trust
UCB Pharma; Novartis; Pfizer

Recruiting

British Axial Spondyloarthritis Inception Cohort (BAxSIC)

Axial Spondyloarthritis

United Kingdom
The Leeds Teaching Hospitals NHS Trust
Genomic Medicine Services Alliance

Completed

Modified Delphi for Genomic Bereavement Care

Genetic Disease | Bereavement | Fetal Anomaly

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
The Urology Foundation, UK

Unknown

Hyaluronate for the Treatment and Prevention of Recurrent Urinary Tract Infection in Women Suffering Atrophic Vaginitis (HATPIN)

Urinary Tract Infections | Atrophic Vaginitis

United Kingdom
Erasmus Medical Center
Radboud University Medical Center; Royal Marsden NHS Foundation Trust; The Netherlands...

Completed

Quality of Life of Patients With Desmoid-type Fibromatosis (QUALIFIED)

Desmoid Tumor | Desmoid-type Fibromatosis

United Kingdom, Netherlands
Royal Marsden NHS Foundation Trust
Imperial College London; Royal Brompton & Harefield NHS Foundation Trust; Institute... and other collaborators

Recruiting

AI & Radiomics for Stratification of Lung Nodules After Radically Treated Cancer (AI-SONAR)

Lung Cancer | Lung Metastases | Indeterminate Pulmonary Nodules | Second Primary Cancer

United Kingdom
King's College Hospital NHS Trust
King's College London; University College London Hospitals; University of Sheffield and other collaborators

Recruiting

RElated Haplo-DonoR Haematopoietic stEm Cell Transplantation for Adults With Severe Sickle Cell Disease (REDRESS)

Sickle Cell Disease

United Kingdom
Liverpool John Moores University
Liverpool University Hospitals NHS Foundation Trust; Royal Liverpool University... and other collaborators

Completed

Can the Health Benefits of a Walking-based Exercise Programme be Enhanced by Co-ingestion of a Lipid-lowering Drug?

Pre-diabetes

United Kingdom
Royal College of Surgeons, Ireland
The Hospital for Sick Children; Massachusetts General Hospital; Belfast Health... and other collaborators

Not yet recruiting

ENHANCE- Establishing Natural History in an Advanced New CF Care Era

Cystic Fibrosis
University of Warwick
Northern Care Alliance NHS Foundation Trust; University Hospitals Coventry... and other collaborators

Unknown

Diagnostic Accuracy of MR in Myositis

Muscular Disorders, Atrophic | Myositis

United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Rigshospitalet, Denmark; Birmingham Women's and Children's NHS Foundation Trust and other collaborators

Unknown

Effect of Insulin Sensitization on IGF-1 Response to Growth Hormone in SGA Children

Small for Gestational Age
University of Warwick
King's College London; The Leeds Teaching Hospitals NHS Trust; University Hospitals...

Active, not recruiting

Breast Screening Atypia and Subsequent Development of Cancer in England

Breast Cancer

United Kingdom
Sarah Cockayne
University of Birmingham; University of York; Chesterfield Royal Hospital NHS...

Recruiting

EXTENDed Antibiotic Durations Compared to Standard Durations for Patients With Complicated Intra-abdominal Infection. (EXTEND)

Complicated Intra-abdominal Infection

United Kingdom
University Hospital Tuebingen
Royal Brompton & Harefield NHS Foundation Trust; National Heart and Lung Institute

Recruiting

Monocentric Registry to Investigate the Role of Platelet Function, Platelet Genetics, Proteomics and Metabonomics in Heart Disease (TuePIC)

Cardiovascular Disease

Germany
University of Edinburgh
Royal Free Hospital NHS Foundation Trust; National Health Service, United Kingdom

Active, not recruiting

The Effect of Varying Brightness on Palpebral Aperture

Eyelid Ptoses

United Kingdom
University Hospital Southampton NHS Foundation...
Imperial College Healthcare NHS Trust; Royal Devon and Exeter NHS Foundation... and other collaborators

Completed

WT1 Immunity Via DNA Fusion Gene Vaccination in Haematological Malignancies by Intramuscular Injection Followed by Intramuscular Electroporation (WIN)

Leukaemia (Acute) | Leukaemia (Chronic) | Leukaemia (Acute Myeloid) | Leukaemia (Acute Lymphoblastic) | Leukaemia (Acute Promyelocytic)

United Kingdom
Dr Michael Scott
Merck Sharp & Dohme LLC; Royal Surrey County Hospital NHS Foundation Trust

Unknown

RADOX' Reduced Abdominal Distension and Oxygen Delivery (RADOX)

Colorectal Cancer

United Kingdom
The Leeds Teaching Hospitals NHS Trust
Leeds Clinical Commissioning Group

Recruiting

Medicines Gaps Study (MeGa)

Adherence, Medication | Statin Adverse Reaction | Anticoagulant Adverse Reaction

United Kingdom
The Leeds Teaching Hospitals NHS Trust
Janssen Pharmaceutica N.V., Belgium

Completed

GOLimumab and Methotrexate Versus Methotrexate in Very Early PsA (GOLMEPsA) (GOLMePsA)

Psoriatic Arthritis

United Kingdom
Sheffield Hallam University
AstraZeneca; Belfast Health and Social Care Trust; Sheffield Teaching Hospitals... and other collaborators

Recruiting

Optimising Secondary Prevention and Quality of Life in Early Cardiac Rehabilitation (OSPREY-CR)

Myocardial Infarction | Cardiovascular Diseases | Coronary Artery Disease | Heart Failure | Coronary Heart Disease | Acute Coronary Syndrome

United Kingdom
Bournemouth University
Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust; Oomph! Wellness and other collaborators

Withdrawn

Effect of an Intervention on Health in Older Care Home Residents

Frail Elderly Syndrome | Frailty | Sedentary Behavior | Life Style Induced Illness | Lifestyle, Sedentary
University College, London
University of Nottingham; Imperial College London; Cambridge University Hospitals... and other collaborators

Unknown

The MRC/ABPI COPD Cohort v1.7 (COPDMAP)

COPD

United Kingdom
Barts & The London NHS Trust
Liverpool Heart and Chest Hospital NHS Foundation Trust; Aortic Dissection...

Recruiting

Living With Marfans and Your Aorta: Surgical Outcomes Study (LIMA II)

Marfan Syndrome | Marfan Syndrome Cardiovascular Manifestations

United Kingdom
Barts & The London NHS Trust
Liverpool Heart and Chest Hospital NHS Foundation Trust; Aortic Dissection...

Not yet recruiting

Mortality and Morbidity Outcomes in Marfans

Marfan Syndrome | Marfan Syndrome Cardiovascular Manifestations
Barts & The London NHS Trust
Liverpool Heart and Chest Hospital NHS Foundation Trust; Aortic Dissection...

Completed

Living With Marfan Syndrome and Your Aorta (LIMA I)

Marfan Syndrome | Marfan Syndrome Cardiovascular Manifestations

United Kingdom
Imperial College London
Medical Research Council; University of Oxford; Guy's and St Thomas' NHS Foundation... and other collaborators

Completed

Research In Viral Eradication of HIV Reservoirs (RIVER)

HIV

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...
Imperial College London; Barts & The London NHS Trust; University of Cambridge; Imperial College Healthcare NHS Trust

Completed

Biomarkers of Acute Serious Illness in Children (BASIC)

Critical Illness | Children, Only | Infection, Mixed

United Kingdom
King's College Hospital NHS Trust
European Association for the Study of the Liver

Recruiting

Liver Disease in Pregnancy

Cirrhosis, Liver | HELLP Syndrome | Intrahepatic Cholestasis of Pregnancy | Pregnancy Disease | AFLP - Acute Fatty Liver of Pregnancy

United Kingdom
Manchester University NHS Foundation Trust
Cambridge University Hospitals NHS Foundation Trust; Norfolk and Norwich University... and other collaborators

Completed

Flash-glucose Monitoring in Sub-optimally Controlled Type 1 Diabetes (FLASH-UK) (FLASH-UK)

Diabetes Mellitus, Type 1

United Kingdom
Queen's University, Belfast
Medical Research Council; Belfast Health and Social Care Trust; NHS Lothian; University... and other collaborators

Completed

Clinimetric Properties of Outcome Measures in Bronchiectasis in the UK

Bronchiectasis

United Kingdom
Hull University Teaching Hospitals NHS Trust
The Hull and East Riding Cardiac Trust Fund

Completed

Cerebral Oximetry in Cardiac Surgery to Reduce Neurological Impairment and Hospital Length-of-stay

Cardiac Surgery | Cerebral Ischemia | Neural Injury
University Hospitals of Derby and Burton NHS Foundation...
University of Nottingham; Northern Care Alliance NHS Foundation Trust; University... and other collaborators

Recruiting

Application of Functional Renal MRI to Improve Assessment of Chronic Kidney Disease (AFiRM)

Chronic Kidney Diseases

United Kingdom
University of Manchester
The Christie NHS Foundation Trust; University Hospital Birmingham; Hampshire... and other collaborators

Completed

Development of an IDEAL Framework to Standardise Cytoreductive Surgery for Colorectal Peritoneal Metastases (IDEAL-PM)

Colorectal Cancer Metastatic | Peritoneal Metastases
The Queen Elizabeth Hospital King's Lynn NHS Foundation...
Novartis Pharmaceuticals

Not yet recruiting

Efficacy of a Streamlined Heart Failure Optimization Protocol (SHORT)

Chronic Heart Failure | Heart Failure With Reduced Ejection Fraction

United Kingdom
Grace Ward
Guy's and St Thomas' NHS Foundation Trust; Royal Berkshire Hospital

Unknown

The Ecological Role of Yeasts in the Human Gut (YIG)

Irritable Bowel Syndrome | Inflammatory Bowel Diseases | Gastrointestinal Disease

United Kingdom

Clinical Trials Sponsored by The Royal Orthopaedic Hospital NHS Trust

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Burkina Faso

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

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