Search clinical trials for: Controlled trials

Total 20146 results

Sandoz

Completed

A Multicenter Placebo-Controlled Double Blind Study to Evaluate the Efficacy and Safety of Sandostatin ( SMS 201-995 ) in Patients With Acquired Immunodeficiency Related Diarrhea Who Were Either "Responders" or "Non-Responders" in a Prior Placebo-Controlled Double-Blind Sandostatin Study.

HIV Infections | Diarrhea

United States
Pharmacia

Completed

Rifabutin Therapy for the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in AIDS Patients With CD4 Counts = or < 200: A Double-Blind, Placebo-Controlled Trial

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States, Canada
Gilead Sciences

Completed

A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Adefovir Dipivoxil When Added to Standard Antiretroviral Therapy for the Treatment of HIV-Infected Patients With CD4 Cell Counts >= 200/mm3

HIV Infections

United States
Ortho Pharmaceuticals

Completed

A Double-Blind, Placebo-Controlled Study With Open-Label Follow-Up To Determine the Safety and Efficacy of r-HuEPO in AIDS Patients With Anemia Induced by Their Disease and AZT Therapy

HIV Infections | Cytopenias

United States
Kaplan Medical Center

Recruiting

A Placebo-controlled Study of Intra-articular Allocetra in Osteoarthritis of the 1st Carpo-metacarpal Joint

Osteoarthritis Thumb

Israel
University College Cork
National University of Ireland, Galway, Ireland

Not yet recruiting

Evaluating a Targeted Selective Speech, Language, and Communication Intervention at Scale - Protocol for the 'Happy Talk' Cluster Randomised Controlled Trial. (HappyTalk)

Developmental Language Disorder and Language Impairment | Deprivation

Ireland
University Hospital, Tours
Fondation Ildys

Not yet recruiting

Impact of a Coordinated Dietetic-adapted Physical Activity Program on the Percentage of Lean Body Mass in Adults With Cystic Fibrosis Treated With Elexacaftor-Tezacaftor-Ivacaftor: Multicentre Randomised Controlled Trial (DIAPASOM)

Cystic Fibrosis

France
Memorial Sloan Kettering Cancer Center
TransThera Sciences

Recruiting

A Study of Tinengotinib (TT-00420) in Combination With Standard Treatments in People With Prostate Cancer

Prostate Cancer

United States
Stemline Therapeutics, Inc.

Not yet recruiting

A Study of Tagraxofusp in Combination With Venetoclax and Azacitidine in Adults With Untreated CD123+ Acute Myeloid Leukemia Who Cannot Undergo Intensive Chemotherapy

Acute Myeloid Leukemia

United States
University Health Network, Toronto
Academic Medical Organization of Southwestern Ontario; York University; Toronto...

Not yet recruiting

Online Psychology Program for Chronic Pain After Surgery (ADOPT-TPS)

Pain, Acute | Pain, Chronic | Post-surgical Pain | Post-Surgical Pain, Chronic

Canada
Cairo University

Not yet recruiting

Effect of Adding Modified Ketogenic Diet to Exercise Program in Treating Obese Patient With Multiple Sclerosis: A Randomized Controlled Trial (MS)

Multiple Sclerosis
Unity Health Toronto

Not yet recruiting

The Genetics Navigator: Evaluating a Digital Platform for Genomics Health Services

Connective Tissue Diseases | Neurodevelopmental Disorders | Retinal Disease | Epilepsy in Children | Cardiac Conditions

Canada
Diabetes Foundation, India
Brightseed

Recruiting

To Evaluate the Impact of Consumption of Bioactive Compounds Extracted From Hemp Hull and Black Pepper on Fasting Blood Glucose Levels in People With Pre-diabetes: A Randomized Placebo-Controlled Parallel Arm Trial

Intervention

India
Regeneron Pharmaceuticals

Not yet recruiting

A Trial to Learn How Well REGN7508 Works for Preventing Blood Clots After a Knee Replacement in Adult Participants (ROXI-VTE II)

Venous Thromboembolism
DermBiont, Inc.
Fortrea

Recruiting

A Randomized, Observer-Blinded, Placebo-Controlled Study on Safety and Efficacy of SM-030 in Adults With Melasma

Melasma

El Salvador
Kasr El Aini Hospital

Recruiting

Dexmedetomidine as an Adjuvant to Bupivacaine in Bilateral PECs for Pain Control After Cardiac Surgeries (PECs)

Post Operative Pain

Egypt
Amsterdam UMC
ZonMw: The Netherlands Organisation for Health Research and Development

Not yet recruiting

Preeclampsia Intervention Netherlands (PI-NL)

Pre-Eclampsia | HELLP Syndrome | Pre-eclampsia or Eclampsia With Pre-existing Hypertension | HELLP | Pre-Eclampsia; Complicating Pregnancy | Pre-Eclampsia Onset Less Than 37 Weeks | Pre-Eclampsia as Antepartum Condition | Pre-Eclampsia; Affecting Fetus | HELLP Syndrome Complicating Pregnancy
Liverpool Heart and Chest Hospital NHS Foundation...
Biolife LLC

Not yet recruiting

Statseal® for Central Venous Catheter Insertion Sites in Critical Care (SCENIC)

Vascular Access | Critical Care | Central Venous Catheter | Central Line | Hemostatic

United Kingdom
University Health Network, Toronto
Canadian Venous Thromboembolism Clinical Trials and Outcomes Research (CanVECTOR)...

Not yet recruiting

TRanEXamic Acid to Decrease Heavy Menstrual Bleeding in Individuals Anticoagulated for Venous Thromboembolism Pilot Study (T-REX HMB)

Venous Thromboembolism | Venous Thromboses | Anticoagulants and Bleeding Disorders | Heavy Menstrual Bleeding
GCS Ramsay Santé pour l'Enseignement et la Recherche

Not yet recruiting

Patient-controlled Sedation With Propofol Versus Anesthesiologist-administered Sedation for Orthopedic Surgery (PACOSA)

Orthopedic Disorder

France
University Ghent
VZW Educatieve Lichaamsbeweging

Recruiting

Changing Trunk Muscle Activation in Patients With Recurrent Low Back Pain in Remission (MAS)

Remission | Recurrent Low Back Pain

Belgium
North Carolina State University
University of North Carolina, Chapel Hill

Recruiting

Restoration of Normative Postural Control

Lower Limb Amputation Below Knee (Injury)

United States
University of Aarhus
Aarhus University Hospital; University of Copenhagen; Gødstrup Hospital; Statens... and other collaborators

Not yet recruiting

The BEGIN Study Bifidobacterium Infantis to Newborns: Effects of Modulating the Gut Microbial Composition on Growth, Immune Function and Inflammatory Conditions - a Randomized Placebo-controlled Double-blinded Intervention Trial (BEGIN)

Healthy | Healthy Nutrition
Bayer

Not yet recruiting

A Study to Learn More About How Well BAY 2927088 Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations in the Genes of Human Epidermal Growth Factor Receptor 2 (HER2)

Advanced Non-small Cell Lung Cancer | HER2 Mutation

United States, Korea, Republic of, Belgium, China, Japan, Taiwan, Denmark, Germany, Israel, Italy, United Kingdom, Bulgaria, Portugal, Switzerland, Greece, Turkey, Sweden, France, Singapore, Mexico, Spain, Netherlands, Poland, Brazil, A... and more
University of Bergen
NKS Olaviken Gerontopsychiatric Hospital

Not yet recruiting

Virtual Darkness Theraphy for Agitation in Dementia (DARKDEM)

Agitation in Dementia, Including Alzheimer's Disease
Regeneron Pharmaceuticals

Not yet recruiting

A First In Human (FIH) Study to Learn if Different Doses of ALN-ANG3 Are Safe and Well Tolerated in Healthy Adults

Healthy Volunteers
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

Safety and Efficacy Study of Pilocarpine HCl Ophthalmic Solution in Participants With Presbyopia

Presbyopia
Fluidx Medical Technology, Inc.
Bright Research Partners

Not yet recruiting

Evaluation of a Simple-Prep Controlled Embolic (GPX)

Renal Cell Carcinoma | Embolism | Bone Tumor | Portal Vein Embolism | Renal Angiomyolipoma | Vascular Tumor
Tris Pharma, Inc.

Not yet recruiting

A Study to Assess the Abuse Potential of Intranasal Cebranopadol

Abuse, Drug

United States
University of Alcala

Not yet recruiting

Effectiveness of Specific Strength Training Combined With Static Stretching of the Posterior Neck in Office Workers With Chronic Neck Pain: A Clinical Trial

Neck Pain | Work Injury
Salvia BioElectronics

Not yet recruiting

Randomized, Double-blind, Sham-controlled Trial to Investigate Combined Occipital and Supra-orbital Neuromodulation in Resistant Migraine. (RECLAIM)

Chronic Migraine | High Frequency Episodic Migraine

Belgium
Mayo Clinic

Not yet recruiting

Turkey Tail Mushroom for Treating Post-Menopausal Women With HER2-Negative ER-Positive Breast Cancer Undergoing Surgery

HER2-Negative Breast Carcinoma | Estrogen Receptor-Positive Breast Carcinoma

United States
Pfizer

Recruiting

A Study in Advanced/Metastatic Solid Tumors With the Study Medicine (PF-07329640) When Given Alone or In Combination (LTbR)

Melanoma | Colorectal Cancer | Non-Small Cell Lung Cancer | Urothelial Cancer | Advanced or Metastatic Solid Tumors

United States, Puerto Rico
Satakunta University of Applied Sciences

Not yet recruiting

Mind Nutrition Study: Nutrition in the Prevention of Depressiveness and Sustaining Work Ability

Quality of Life | Depressive Symptoms | Eating Behavior | Nutrition, Healthy | Work-Related Condition

Finland
New York University
Joon, Inc.

Recruiting

Randomized Controlled Trial of a Behavioral Training App

Depression | Stress | Anxiety | Executive Dysfunction | Behavior, Child | Disruptive Behavior | Attention-deficit

United States
BioNTech SE

Not yet recruiting

Safety, Preliminary Effectiveness of BNT327, an Investigational Therapy for Patients With Small-cell Lung Cancer in Combination With Chemotherapy

Small-cell Lung Cancer | Extensive-stage Small-cell Lung Cancer
Clinica Universidad de Navarra, Universidad de...
Biobizkaia; Genbioma Aplicaciones S.L.

Not yet recruiting

Effect of a Postbiotic Intake on Glucose Control and Microbiota Composition of Type 2 Diabetic Subjects: a Randomized Controlled Trial. (Diabet2Predict)

Diabetes Mellitus, Type 2

Spain
BioNTech SE

Not yet recruiting

Safety and Preliminary Effectiveness of BNT327, an Investigational Therapy for Breast Cancer, When Given in Combination With Chemotherapy

Triple Negative Breast Cancer | Locally Advanced Breast Cancer
University of Maryland, Baltimore

Not yet recruiting

Effect of RECK in Posterior Spinal Fusion

Degenerative Disc Disease | Degenerative Spondylolisthesis | Degenerative Lumbar Spinal Stenosis | Degenerative Disease

United States
Fujian Shengdi Pharmaceutical Co., Ltd.

Not yet recruiting

Safety, Tolerability, and Preliminary Efficacy of HRS-7450 Injection in the Treatment of Acute Ischemic Stroke: a Multi-center, Randomized, Double-blind, Double-dummy, Placebo-controlled Clinical Trial

Acute Ischemic Stroke

China
GlaxoSmithKline

Not yet recruiting

Long-Term Study (AtDvance) to Evaluate GSK1070806 in Atopic Dermatitis. (AtDvance)

Dermatitis, Atopic

United States, Germany, Spain, France, Italy, Japan, China, Argentina, Greece, Czechia, Korea, Republic of, Panama, Bulgaria, Canada, Poland, Mexico, Thailand
University of Chicago

Not yet recruiting

Using Text Messages to Improve Oral Chemotherapy for Adolescents and Young Adults With Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia

United States
Pamukkale University

Recruiting

Client-Centered Breastfeeding Support: Effects on Primipara Mothers in a Randomized Trial Breastfeeding Self-Efficacy, Attitudes, and Problems in Primiparous Mothers: A Randomized Controlled Trial

Breastfeeding Self-Efficacy Attitude to Health Postpartum Period Primiparity

Turkey
Ascidian Therapeutics, Inc

Recruiting

Prescreening Study to Identify Potential Participants for ACDN-01 Clinical Trials

Stargardt Disease | Stargardt Disease 1 | Juvenile Macular Degeneration | Cone Rod Dystrophy

United States
Breast Cancer Trials, Australia and New Zealand

Not yet recruiting

Post-operative Radiotherapy Omission in Selected Patients With Early Breast Cancer Trial International Validation Experience (PROSPECTIVE)

Breast Cancer | Breast Cancer Female
Scholar Rock, Inc.

Recruiting

Efficacy and Safety of Apitegromab for the Treatment of Adults Who Are Overweight or Obese (EMBRAZE)

Overweight and Obesity

United States
Columbia University
University of Southern California; Abdul Latif Jameel Poverty Action Lab; Bowdoin... and other collaborators

Not yet recruiting

E-mail Nudges for Prescribing Risky Drugs

Opioid Prescribing | Prescription Drug Misuse

United States
University of Sydney
Woke Pharmaceuticals

Not yet recruiting

Psilocybin-assisted Therapy for Alcohol Use Disorder

Depression | Alcohol Dependence | Anxiety | Alcohol Use Disorder
Mayo Clinic

Not yet recruiting

An Investigational Scan (Ga-68 PSMA-11 PET/CT) for Detection of Disease Recurrence or Progression in Patients With Glioma

WHO Grade 3 Glioma | WHO Grade 2 Glioma | WHO Grade 4 Glioma

United States
Regeneron Pharmaceuticals

Not yet recruiting

Assessment of Gastrointestinal Blood Loss After Receiving Aspirin or Aspirin Plus Rivaroxaban, or Aspirin Plus REGN9933, or Aspirin Plus REGN7508 in Healthy Adult Participants

Healthy Volunteers

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