Search clinical trials for: Dose Response

Total 33143 results

Assiut University

Completed

Attenuation of Hemodynamic Response to Laryngoscopy and Endotracheal Intubation With Single Dose of Dexmedetomidine in Hypertensive Patients.

Stress Response During Laryngoscopy Intubation

Egypt
ContraFect

Completed

A Placebo-Controlled, Dose-Escalating Study to Examine the Safety and Tolerability of Single Intravenous Doses of CF-301 in Healthy Subjects

Staphylococcus Aureus Bloodstream Infections (BSI; Bacteremia)

United States
Pfizer

Completed

Duration of hSBA Response After a Primary Series of Bivalent rLP2086 Followed by a Booster Dose

Meningococcal Infection

United States, Finland, Czechia, Sweden, Denmark, Germany
Centre Leon Berard

Terminated

Tumour and HEalthy Tissues DOse-response and Radiosensitivity Assay (THEODORA)

Sarcoma | Rectal Carcinoma | Esophagus Cancer

France
National Cancer Institute (NCI)
Southwest Oncology Group

Completed

Capecitabine and Lapatinib Ditosylate With or Without Cixutumumab in Treating Patients With Previously Treated HER2-Positive Stage IIIB-IV Breast Cancer

Recurrent Breast Carcinoma | HER2 Positive Breast Carcinoma | Stage IV Breast Cancer AJCC v6 and v7 | Stage IIIB Breast Cancer AJCC v7 | Stage IIIC Breast Cancer AJCC v7

United States
Mahidol University

Completed

Seroprevalence of Bordetella Pertussis Antibodies and Anti-pertussis Antibody Response After a Single Dose of Tdap in Pregnant Thai Women

Pertussis | Pregnancy Related

Thailand
University of Kansas Medical Center

Completed

Assessing a Dose-Response Relationship of Hydralazine and Its Effects on DNA Methyltransferase 1 in Polycystic Kidney Disease Patients

Polycystic Kidney Diseases

United States
GlaxoSmithKline

Completed

Response to GSK Biologicals' Tritanrix-HepB/Hib-MenAC Vacc (4th Dose) at 15-24m & Mencevax ACWY at 24-30m

Hepatitis B | Tetanus | Diphtheria | Haemophilus Influenzae Type b | Whole Cell Pertussis | Diphtheria-Tetanus-Pertussis-Hepatitis B-Haemophilus Influenzae Type b-Neisseria Meningitidis Vaccin

Thailand
Fundación Pública Andaluza para la gestión de la...

Unknown

Monitoring of Piperacillin-Tazobactam and Meropenem Plasmatic Levels in Critical Patients

Sepsis | Septic Shock

Spain
Merck Sharp & Dohme LLC
Department of Health and Human Services; BioProtection Systems Corporation

Completed

Placebo Controlled, Dose Response, Safety and Immunogenicity Study of Vesicular Stomatitis Virus (VSV) Ebola Vaccine in Healthy Adults (V920-004)

Ebola Virus
Unilever R&D
Lambda Therapeutic Research Ltd.

Completed

Dose Response Study of a Natural Extract for Reducing Post Prandial Blood Glucose

Blood Glucose

India
McGill University
Dairy Farmers of Canada

Completed

Family Milk Product Two-year Dose-response Study to Enhance Bone Health (FAMILY)

Healthy

Canada
Eisai Inc.

Completed

A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group, Bayesian Adaptive Randomization Design, Dose Response Study of the Efficacy of E2006 in Adults and Elderly Subjects With Chronic Insomnia

Elderly | Chronic Insomnia | Adults

United States
Allarity Therapeutics
Medical Prognosis Institute A/S; Smerud Medical Research International AS

Terminated

Safety and Pharmacokinetics of Rising Doses of APO010 in Relapsed/Refractory Multiple Myeloma Patients Selected by DRP (SMR-3184)

Relapsed/Refractory Multiple Myeloma

Denmark
Westat
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy...

Completed

Evaluating the Response to Two Antiretroviral Medication Regimens in HIV-Infected Pregnant Women, Who Begin Antiretroviral Therapy Between 20 and 36 Weeks of Pregnancy, for the Prevention of Mother-to-Child Transmission

HIV Infections

United States, Puerto Rico, Thailand, Argentina, Brazil, South Africa, Tanzania
Tianjin Chasesun Pharmaceutical Co., LTD
Southwest Hospital, China

Completed

Study of Multiple-dose Kukoamine B Mesilate in Sepsis Patients

Sepsis

China
Merck Sharp & Dohme LLC

Completed

Dose Response Finding Study of MK-0431/ONO-5435 in Japanese Subjects With Impaired Glucose Tolerance (MK-0431-105)

Glucose Intolerance
Yonsei University

Completed

Treatment Response of Maintenance Dose of Proton Pump Inhibitor in Patients With Nonerosive Gatroesophageal Reflux Disease

Non-erosive Gatroesophageal Reflux Disease

Korea, Republic of
Institut National de la Santé Et de la Recherche...

Completed

Study of BPZE1 (High Dose) Nasal Live Attenuated B. Pertussis Vaccine

Pertussis | Whooping Cough

Sweden
GlaxoSmithKline

Completed

A Study to Evaluate Immune Response and Safety of Two Doses of GSK Biologicals' HRV Liquid Vaccine in Healthy Infants.

Infections, Rotavirus | Rotavirus Vaccines

Philippines
Marshfield Clinic Research Foundation
Centers for Disease Control and Prevention

Completed

Open-Label Influenza Vaccine Evaluation (OLIVE)

Immune Response

United States
National Institute of Allergy and Infectious Diseases...

Withdrawn

A Phase 1, Open Label, Ascending Dose Cohort Study of the Pharmacokinetics of Anti-Influenza Hyperimmune Intravenous Immunoglobulin in Healthy Subjects

Influenza | Flu
National Institute of Allergy and Infectious Diseases...

Withdrawn

Effect of Concomitant Mansonella Perstans Microfilaremia on Immune Responses Following Single Dose Praziquantel in People With Schistosomiasis

Schistosomiasis
Turku University Hospital
University of Turku; University of Helsinki

Completed

Dose-response of Ketamine in Patient Controlled Analgesia in Orthopaedic Surgery Patients (DoseRespKeta)

Pain, Postoperative

Finland
University of Saskatchewan
AstraZeneca

Completed

Melancholic Depression and Insomnia as Predictors of Response to Quetiapine in Patients With Major Depression

Depressive Disorder, Major
Rigshospitalet, Denmark

Completed

High vs Low Dose Dexamethasone on Complications in the Immediate Postoperative Phase After Mastectomy (DEX-MAS)

Systemic Inflammatory Response Syndrome | Pain, Postoperative | Postoperative Complications | Breast Cancer | Mastectomy | Dexamethasone | Nausea and Vomiting, Postoperative | Glucocorticoids | Steroid

Denmark
Cairo University

Completed

Lidocaine-Ketamine Versus Ketamine for Induction of Anesthesia in Septic Shock Patients

Septic Shock

Egypt
GlaxoSmithKline

Completed

Immunogenicity and Safety Study of GlaxoSmithKline Biologicals' Human Papillomavirus (HPV) Vaccine (GSK-580299) and Merck's Gardasil Vaccine When Administered According to Alternative 2-dose Schedules in 9-14 Year Old Females

Infections, Papillomavirus

Singapore, Hong Kong, France, Sweden
Arizona State University
United States Dry Bean Council

Completed

Glycemic Response of Bean-and-rice Meals in Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus | Blood Glucose

United States
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Completed

A Dose-response of the Effects of Exendin-9,39 on GI Symptoms and Food Intake

Obesity | Diabetes | Roux-en-Y Gastric Bypass

United States
Mahidol University
Ministry of Health, Thailand; Bhumirajanagarindra Kidney Institute, Thailand

Completed

Immune Response to Influenza Vaccine in ESRD Patients

Immunology | Nephrology
Massachusetts General Hospital
AbbVie; AstraZeneca; National Institute on Aging (NIA); Solvay Pharmaceuticals

Completed

Dose-Response of Gonadal Steroids and Bone Turnover in Older Men

Healthy Volunteers

United States
UMC Utrecht
Maastro Clinic, The Netherlands

Unknown

RECTAL BOOST Study (RECTAL BOOST)

Rectal Cancer

Netherlands
Dance Biopharm Inc.
Profil Institut für Stoffwechselforschung GmbH

Completed

Dose Response of Dance 501 in Subjects With Type 2 Diabetes Mellitus (T2DM)

Type 2 Diabetes Mellitus

Germany
University Hospital, Basel, Switzerland
University of Erlangen-Nürnberg

Completed

Dose-Response Relationship of Ambulatory Load and Cartilage - Pilot Study (COMP)

Healthy

Switzerland
Alexion Pharmaceuticals

Completed

Pharmacokinetic and Dose Response Study of Asfotase Alfa in Adult Patients With Pediatric-Onset Hypophosphatasia (HPP)

Hypophosphatasia

United States, Germany
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Terminated

FDG-PET Directed Treatment in Improving Response in Patients With Locally Advanced Stomach or Gastroesophageal Junction Cancer

Gastric Cancer | Gastric Adenocarcinoma | Adenocarcinoma of the Gastroesophageal Junction

United States
AbbVie

Completed

Efficacy and Safety of 8-weeks of Glecaprevir/Pibrentasvir in Treatment-Naïve Adults With HCV Genotype 1-6 and Aspartate Aminotransferase to Platelet Ratio Index (APRI) ≤1

Hepatitis C Virus (HCV)

United States, Bulgaria, Canada, France, Germany, Poland, Puerto Rico, Russian Federation, Spain, United Kingdom
Nemours Children's Clinic
University of Florida

Completed

A Within Subjects Comparison of Two Antegrade Flushing Regimens in Children

Neurogenic Bowel | Fecal Incontinence

United States
Cork University Hospital
National University of Ireland, Galway, Ireland; John Hunter Children's Hospital

Completed

What is the Dose Response of Varying Meal Content of Fat on Postprandial Glycaemia in Children With T1DM? (REQINSOIL)

Diabetes Mellitus, Type 1

Ireland
University of Maryland, Baltimore

Completed

Low-dose Iron Supplementation and Markers of Iron Status Among Non-anemic, Iron-deficient Women

Non-anemic Iron Deficiency

United States
Weill Medical College of Cornell University
Memorial Sloan Kettering Cancer Center

Withdrawn

Dose Response of Functionally Critical Brain Regions for Brain Radiotherapy

Brain Tumors

United States
Northwestern University
Ortho-McNeil Janssen Scientific Affairs, LLC

Completed

High Dose Risperidone Consta for Patients With Schizophrenia With Poor Response to Risperidone

Schizophrenia | Schizoaffective Disorder

United States
Actavis Inc.

Completed

The Dose-response "Pilot" Study of Topically Delivered Clobetasol Propionate Lotion in Healthy Adult Subjects

Healthy

United States
Mỹ Đức Hospital

Completed

Long-term Endogenous Androgen Priming in Bologna Criteria Poor Responder Patients - A Pilot Study

Poor Ovarian Response

Vietnam
Seoul National University Hospital
IlDong Pharmaceutical Co Ltd

Completed

Treatment Response of High-dose and Standard-dose Rabeprazole for Extra-esophageal Reflux.

Esophageal Disease

Korea, Republic of
Maria Sklodowska-Curie National Research Institute...

Active, not recruiting

Hypofractionated Radiotherapy in Locally Advanced Myxoid Liposarcomas of Extremities or Trunk Wall (LIPO-MYX Trial) (LIPOMYX)

Myxoid Liposarcoma

Poland
Pfizer

Completed

The Long-term Antibody Persistence of MenACWY-TT Vaccine (PF-06866681) Versus Meningitec(Registered) or Mencevax(Registered) ACWY in Healthy Adolescents and Adults and a Booster Dose of MenACWY-TT Administered 10 Years Post Primary Vaccination

Infections, Meningococcal

Finland
M.D. Anderson Cancer Center

Completed

Decitabine Followed by Clofarabine, Idarubicin, and Cytarabine in Acute Leukemia

Leukemia

United States
Centre Oscar Lambret
Institut de Biologie de Lille

Terminated

Early Biomarkers of Tumor Response in High Dose Hypofractionated Radiotherapy Word Package 3 : Immune Response

Melanoma | Kidney Neoplasms | Carcinoma, Hepatocellular | Colorectal Neoplasms

France

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