Search clinical trials for: Drug review

Total 262059 results

Wake Forest University Health Sciences
National Cancer Institute (NCI)

Terminated

Adherence Monitoring System in Managing Myelosuppression in Patients With Newly Diagnosed Malignant Gliomas Receiving Temozolomide and Radiation Therapy

Malignant Glioma | Myelosuppression

United States
University of Iowa
University of Minnesota

Completed

Scopolamine Patch Pharmacokinetics in Healthy Adults

Healthy

United States
Baylor College of Medicine

Completed

Review of Diagnostic Yield of MRI Brain Results in Children Under Age 3 Years

Seizures | Development Delay | Anesthetic Neurotoxicity

United States
University of Toronto
Canadian Institutes of Health Research (CIHR); European Foundation for the...

Unknown

Umbrella Review and Updated Systematic Review and Meta-analysis of Pulses/Legumes and Incident Cardiometabolic Diseases

Cardiovascular Diseases | Stroke | Hypertension | Obesity | Diabetes Mellitus, Type 2 | Coronary Heart Disease

Canada
Genesis Pharma S.A.

Completed

A Retrospective Chart Review Study of the Outcomes of 2nd Line Therapy With LEn/Dex in Greek Patients With R/R Multiple MyEloma and the Treatment PatterNs Following Progressive Disease (LEGEND)

Relapsed/Refractory Multiple Myeloma

Greece
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0713: Oxaliplatin, Capecitabine, Cetuximab, and RT Followed By Surgery in Pts W/Stage II or III Rectal Cancer

Colorectal Cancer

United States
Hadassah Medical Organization

Unknown

Clinical Pharmacist Anticoagulant Stewardship

Safety Issues | Anticoagulant Toxicity

Israel
UNICANCER
AstraZeneca

Completed

Radiation Therapy With or Without Goserelin in Treating Patients Who Have Undergone Surgery for Recurrent or Refractory Prostate Cancer

Prostate Cancer

France
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Bevacizumab and Sorafenib in Treating Patients With Recurrent Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Brostallicin and Cisplatin in Treating Patients With Metastatic Breast Cancer

Triple-negative Breast Cancer

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Fulvestrant and Bevacizumab in Treating Patients With Metastatic Breast Cancer

Breast Cancer

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Bevacizumab and Temozolomide or Bevacizumab and Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin in Treating Patients With Stage IV Malignant Melanoma That Cannot Be Removed by Surgery

Melanoma (Skin)

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0809: Capecitabine, Gemcitabine, and RT in Patients w/Cholangiocarcinoma of the Gallbladder or Bile Duct

Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Docetaxel, Oxaliplatin, Capecitabine, Fluorouracil, and Radiation Therapy in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction

Gastric Cancer | Esophageal Cancer | Adenocarcinoma of the Gastroesophageal Junction

United States
Peking Union Medical College Hospital

Unknown

Registry Study for Pregnant Women With Iodine Overload

Iodine Overload in Pregnancy
Isfahan University of Medical Sciences

Unknown

The Effectiveness of Vancomycin in Comarison With Cefazolin in Prevention of SSI After Craniotomy

Elective Craniotomy-candidated Patients

Iran, Islamic Republic of
GE Healthcare

Completed

Meta-Iodobenzylguanidine (123I-mIBG) Scintigraphy Imaging in Patients With Heart Failure and Control Subjects Without Cardiovascular Disease

Heart Failure, Congestive

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S1105: Text-Messaging Intervention to Reduce Early Discontinuation of AI Therapy in Women With Early-Stage Breast Cancer

Breast Cancer

United States
University Health Network, Toronto
CIHR Canadian HIV Trials Network

Completed

Can Valacyclovir Delay the Need for Initiation of Human Immunodeficiency Virus (HIV) Treatment in HIV-infected Individuals? (VALIDATE)

HIV Infections | HIV Infection | Herpes Simplex Type II

Canada, United Kingdom, Argentina, Brazil
IRCCS Azienda Ospedaliero-Universitaria di Bologna
University of Bologna; Catholic University of the Sacred Heart; Michigan State... and other collaborators

Completed

Combined, Intensified and Modulated Adjuvant Therapy in Prostate Carcinoma

Prostate Cancer
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0410 Tandem Stem Cell Transplantation in Treating Patients With Progressive or Recurrent Hodgkin's Lymphoma

Lymphoma

United States
FHI 360

Completed

Long-Acting Reversible Contraception (LARC)

Contraception

United States
Siriraj Hospital

Completed

Scheduled Elective Surgical Case Cancellation in Siriraj: Evaluation and Identification of the Reasons

Peer Review, Research

Thailand
M.D. Anderson Cancer Center

Completed

Parathyroid Cancer Versus Atypical Parathyroid Neoplasm; Investigating Their Clinical Characteristics and Biological Behavior

Parathyroid Carcinoma | Parathyroid Neoplasm

United States
Sharp HealthCare

Completed

IL-10 Stratifying Tool for Towards Antibiotic Selection for MRSaB

Bacteremia

United States
Oslo University Hospital
University of Oslo; The Research Council of Norway

Completed

Cooperation for Improved Pharmacotherapy in Home-dwelling Elderly People Receiving Polypharmacy - The COOP Study (COOP)

Drug Usage

Norway
Pinyo Rattanaumpawan

Unknown

Vancomycin Dosage Adjustment for MRSA Infections

Methicillin-Resistant Staphylococcus Aureus

Thailand
Seoul National University Hospital

Completed

Evaluate the Effects of the Environmental Change in Intestine by Antibiotics on the Pharmacokinetic Characteristics of Simvastatin in Healthy Male Volunteers

Simvastatin Pharmacokinetics and Gut Microbiome

Korea, Republic of
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Rituximab, Cladribine, and Temsirolimus in Treating Patients With Newly Diagnosed Mantle Cell Lymphoma

Lymphoma

United States
Ain Shams University

Completed

Neuroablation Versus Neuromodulation Techniques for Treatment of Secondary Dystonia

Secondary Dystonia
Unity Health Toronto

Unknown

The Effect of Psyllium Fibre on LDL-C, Non-HDL-C, and Apolioprotein-B: A Systematic Review and Meta-analysis

Hypercholesterolemia | Cardiovascular Risk Factor
St. Louis University

Withdrawn

Retrospective Review of NSAIDS in the Postpartum Period

Post Partum Pain

United States
DUSA Pharmaceuticals, Inc.

Withdrawn

Phase 3 Study of Levulan With New Blue Light for AK on the Face or Scalp

Actinic Keratosis

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0601 Rituximab, Combination Chemotherapy, and Bortezomib Followed by Bortezomib Alone in Treating Patients With Newly Diagnosed Mantle Cell Lymphoma

Lymphoma

United States
Santhera Pharmaceuticals

Completed

A Study to Assess the Potential for Pre-systemic Inhibition of CYP3A by Idebenone Using Midazolam as a Substrate

Drug-Drug Interaction

France
FHI 360
Bill and Melinda Gates Foundation

Completed

Safety,Effectiveness and Acceptability of Sino-implant II in DR

Contraception

Dominican Republic
NSABP Foundation Inc
National Cancer Institute (NCI)

Unknown

Chemotherapy With or Without Bevacizumab in Treating Women With Stage I, Stage II, or Stage IIIA Breast Cancer That Can Be Removed By Surgery

Breast Cancer

United States, Canada, Puerto Rico
Boston Children's Hospital
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Withdrawn

Placebo Controlled Study of Baclofen for GERD in Children With Cerebral Palsy

Cerebral Palsy | GERD

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Sanofi; Pfizer

Completed

Irinotecan, Oxaliplatin, and Capecitabine as First-Line Therapy in Treating Patients With Metastatic or Unresectable Locally Advanced Small Bowel Cancer

Recurrent Small Intestine Cancer | Small Intestine Adenocarcinoma

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Temozolomide and Everolimus in Treating Patients With Stage IV Melanoma That Cannot be Removed by Surgery

Melanoma (Skin)

United States
University of Toronto
Canadian Institutes of Health Research (CIHR); Canadian Diabetes Association; The Physicians' Services Incorporated Foundation and other collaborators

Unknown

Meta-Analyses of Low-risk Lifestyle Behaviours and Patient Important Outcomes

Cardiovascular Disease | Diabetes | Cancer | Mortality

Canada
Children's Hospitals and Clinics of Minnesota
UnitedHealth Group

Completed

Diabetes Care Transformation: Diabetes Data Registry and Intensive Remote Monitoring (DCT1A)

Type 1 Diabetes Mellitus

United States
National Institutes of Health Clinical Center (CC)

Completed

Cardiomyopathy Following Stem Cell Transplantation

Cardiomyopathy

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Panobinostat and Letrozole in Treating Patients With Metastatic Breast Cancer

Breast Cancer

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0800, Nab-Paclitaxel, Doxorubicin, Cyclophosphamide, and Pegfilgrastim With or Without Bevacizumab in Treating Women With Inflammatory or Locally Advanced Breast Cancer

Breast Cancer

United States, Puerto Rico
Aymen N Naguib

Completed

Retrospective Review of Anesthetic Considerations for Pulmonary Artery Rehabilitation

Tetralogy of Fallot | Pulmonary Atresia | Pulmonary Artery Stenosis

United States
Baylor Research Institute
American Diabetes Association

Completed

Improving Diabetes Care:Effectiveness of Physician Profiling and Care Coordination by a Diabetes Resource Nurse

Diabetes Mellitus

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Terminated

Photodynamic Therapy Using Topical Aminolevulinic Acid in Treating Patients With Actinic Keratosis

Precancerous/Nonmalignant Condition

United States
Southwest Oncology Group
National Cancer Institute (NCI); University of Southern California; NCIC Clinical...

Terminated

4B951, Combination Chemotherapy in Treating Patients With Bladder Cancer

Bladder Cancer

United States, Canada
Bayer

Completed

A Study to Understand the Treatment Patterns in Patients With Pulmonary Arterial Hypertension or Chronic Thromboembolic Pulmonary Hypertension During a Switch of Treatment to Adempas in Real-life Clinical Practice (CAPTURE)

Hypertension, Pulmonary

Japan, Germany, Sweden, Colombia, Turkey, Belgium, Canada

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