Search clinical trials for: First Time in Humans

Total 458258 results

Duke University

Completed

Efficacy of First Time Anterior Shoulder Decision Tool

Shoulder Dislocation

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Positron Emission Tomography in Determining Stage of Esophageal Cancer

Esophageal Cancer

United States
GlaxoSmithKline

Completed

A Study To Investigate The Safety And Metabolism Of GSK376501 In Overweight Subjects

Type 2 Diabetes Mellitus

United States
Merck KGaA, Darmstadt, Germany

Completed

Cilengitide and Cetuximab in Combination With Platinum-based Chemotherapy as First-line Treatment for Subjects With Advanced Non Small Cell Lung Cancer (NSCLC) (CERTO)

Carcinoma, Non-Small-Cell Lung

France, Italy, Poland, Spain, Germany, Belgium, Ireland, Czech Republic
Novo Nordisk A/S

Completed

Safety of rFXIII in Patients Following First Time Myocardial Revascularization Requiring Cardiopulmonary Bypass

Acquired Bleeding Disorder | Cardiac Surgery Requiring Cardiopulmonary Bypass

United States, Denmark, United Kingdom, Germany, Canada
Hospital for Special Surgery, New York

Completed

Effect of Steroids on Thrombosis (Blood Clot Formation) and Inflammation in Patients Undergoing Hip Surgery

Total Hip Replacement

United States
VHsquared Ltd.

Completed

A First Time in Human Study in Healthy Volunteers and Patients

Crohn's Disease

United Kingdom
Transgene

Terminated

Phase IIB/III Of TG4010 Immunotherapy In Patients With Stage IV Non-Small Cell Lung Cancer (TIME)

Non-Small-Cell Lung Carcinoma

United States, France, Hungary, United Kingdom, Spain, Israel, Belgium, Germany, Poland, Italy
Shalvata Mental Health Center

Unknown

The Experience of Older Adults Facing Depression for the First Time in Old Age

MAjor Depressive Disorder

Israel
Jilin University

Unknown

The Advantages and Disadvantages Between Uncut Roux-en-Y Reconstruction and Billroth II Reconstruction After Laparoscopy-assisted Distal Gastrectomy for Gastric

Gastric Cancer

China
Duke University

Completed

Intra-Arterial Microdosing: Proof-of-Concept in Humans (IAM-POC)

Healthy

United States
The First Affiliated Hospital of Zhengzhou University

Unknown

The Application of Time-lapse System in IVF/ICSI

the Application of Time-lapes System in IVF/ICSI

China
Shanghai First Maternity and Infant Hospital

Unknown

A Study Select Top-grade Embryo by Time-lapse Imaging

Top-grade Embryo

China
The First Affiliated Hospital of Guangzhou Medical...

Completed

Study of Neural Inspiratory Time and Expiratory Delay in Patient and Health During Spontaneous Breathing and Ventilation

State Key Laboratory of Respiratory Disease

China
First Affiliated Hospital, Sun Yat-Sen University

Unknown

Effect of Fasting Therapy on Blood Glucose Control and Islet Function in Newly Diagnosed Type 2 Diabetic Patients

Type 2 Diabetes Mellitus

China
Martin-Luther-Universität Halle-Wittenberg

Completed

Risk-adapted Screening in First-degree Relatives of Patients With Colorectal Cancer (FAMKOL)

Colorectal Neoplasms

Germany
Ohio University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Preventing Negative Reactions in First Time Blood Donors to Encourage Subsequent Blood Donations

Syncope, Vasovagal

United States
University of Benin

Completed

Best Partograph Action Line to Prevent Prolonged Labour (Partograph)

Prolonged First Stage Labor - Prevention
Merck Sharp & Dohme LLC

Withdrawn

A Study to Assess the Effects of MK0822 in Prolonging Time to First Bone Metastasis in Men With Castration-Resistant Prostate Cancer (0822-030)

Prostate Cancer
First Affiliated Hospital Xi'an Jiaotong University

Unknown

Optimal Time for Tenofovir Treatment of Anti-Hepatitis B Virus (HBV) During the Pregnancy

Hepatitis B, Chronic

China
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Proteomic Profiling in Diagnosing Non-Small Cell Lung Cancer in Patients Who Are Undergoing Lung Resection for Suspicious Stage I Lung Lesions

Lung Cancer

United States, Canada
Eli Lilly and Company

Completed

A Study of Gemcitabine-Cisplatin Chemotherapy Plus Necitumumab in the First-Line Treatment of Participants With Squamous Lung Cancer

Non-small Cell Lung Cancer

Spain, France, United States, Taiwan, Canada, Netherlands, Mexico
University of Toronto

Completed

Short Term Omega-3 Supplementation on Performance

Muscle Strength | Muscle Fatigue

Canada
West China Hospital
Zhejiang Cancer Hospital; Hebei General Hospital; Beijing Tongren Hospital; The... and other collaborators

Unknown

Comparison of SUV Using SPECT/CT Between Grave's Disease Patients and Normal Humans

Hyperthyroidism | Tomography | Emission-Computed | Single-Photon

China
Makerere University

Completed

CAUDAL BUPIVACAINE VERSUS INTRAVENOUS MORPHINE ON TIME TO FIRST ANALGESIC REQUIREMENT (CaBuMorph)

Post Operative Pain

Uganda
Kinderkrankenhaus auf der Bult

Unknown

Therapeutic Effect of the Wireless Micro Current Stimulation in Pediatric Deep Dermal Burns and Scald Injuries (ELSTHER)

Burns

Germany
Istanbul University

Completed

Axillary Block Properties in Diabetic Patients

Pain, Postoperative | Diabetes Mellitus | Nerve Block Duration

Turkey
National Cancer Institute (NCI)

Completed

Selumetinib and Akt Inhibitor MK2206 or mFOLFOX Therapy Comprising Oxaliplatin and Fluorouracil in Treating Patients With Metastatic Pancreatic Cancer Previously Treated With Chemotherapy (S1115)

Pancreatic Ductal Adenocarcinoma | Recurrent Pancreatic Carcinoma | Stage IV Pancreatic Cancer | Pancreatic Acinar Cell Carcinoma

United States
Peking University Cancer Hospital & Institute

Unknown

A Phase II Trila of Sunitinib Schedule 4/2 vs. Shedule 2/1 as First Line Therapy in Metastatic Renal Cell Carcinoma.

Metastatic Renal Cell Carcinoma

China
Istanbul University

Completed

Ultrasound-Guided Thoracic Paravertebral Blocks in Patients Undergoing Reduction Mammoplasty

Pain, Postoperative

Turkey
First Affiliated Hospital of Jinan University

Completed

Hospital Processes Reengineering of Intravenous Thrombolysis in Acute Ischemic Stroke in China (PROMISE)

Ischemic Stroke | Adverse Effect of Thrombolytic Drugs, Sequela
The First Affiliated Hospital of Guangzhou Medical...

Unknown

Effect of Vinegar Consumption on 24-hour Urinary Risk Factors Associated With Stone Formation

Urolithiasis

China
Hoffmann-La Roche

Completed

An Observational Study of Erlotinib (Tarceva) as Second-line Treatment in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer After Failure of Pemetrexed in First-line Therapy (TIME)

Non-Squamous Non-Small Cell Lung Cancer

Belgium
The First Affiliated Hospital of Henan University...

Unknown

Clinical Study of Time Optimizing of Endoscopic Photodynamic Therapy on Esophageal and/or Gastric Cardiac Cancer

Stage III Esophageal Squamous Cell Carcinoma | Stage II Esophageal Squamous Cell Carcinoma | Stage I Esophageal Adenocarcinoma | Stage II Esophageal Adenocarcinoma | Stage III Esophageal Adenocarcinoma | Stage I Esophageal Squamous Cell Carcinoma

China
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0424 - Carcinogens in Lung Tissue From Smokers (Closed to Entry as of 7/15/07) and Non-Smokers With Newly Diagnosed Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer

Lung Cancer

United States
Chongqing Medical University

Completed

Pharmacokinetic and Pharmacodynamic Profile of Insulin Lispro Using Needle-Free Jet Injection Technology

Healthy

China
Assistance Publique Hopitaux De Marseille

Unknown

Efficacy of Lidocaine Versus Placebo in Palliative Care Patients With Opioid-refractory Cancer Pain With Neuropathic Component: a Multicenter, Prospective, Double-blind Randomized Placebo-controlled Study. (LIDOSP)

Cancer | Pain With Neuropathic Component

France
The Second Hospital of Anhui Medical University
The First Affiliated Hospital of Anhui Medical University

Unknown

One-layer Versus Two-layer Duct-to-mucosa Pancreaticojejunostomy After Pancreaticoduodenectomy

Pancreatic Fistula

China
University of California, Davis

Completed

The First Therapeutic Intervention in Malignant Pleural Effusion Trial (TIME-1)

Pleural Effusion | Malignant Pleural Effusion

United States
Gloucestershire Hospitals NHS Foundation Trust

Unknown

Time Interval Between TVT and First Void (TIBT) Study (TIBT)

Stress Urinary Incontinence
The First Affiliated Hospital of Dalian Medical...
Fudan University

Completed

Timing for Bone Marrow Mononuclear Cells After Acute Myocardial Infarction

Myocardial Infarction
The First Affiliated Hospital of Zhengzhou University

Unknown

The Effectiveness of Endometrial Injury in IVF

Infertility

China
Chengdu University of Traditional Chinese Medicine
Guang'anmen Hospital of China Academy of Chinese Medical Sciences

Completed

Acupuncture for Patients With Diarrhea-predominant IBS or Functional Diarrhea: a Randomized Controlled Trial

Diarrhea-predominant Irritable Bowel Syndrome | Functional Diarrhea

China
AstraZeneca

Completed

A First Time in Man Study to Asses the Safety and Tolerability of AZD7624 in Healthy Subjects

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
Boston Scientific Corporation

Completed

Safety Study to Assess the Feasibility of Use in Humans of the TAXUS Petal Bifurcation Coronary Stent System

Cardiovascular Diseases

New Zealand, France, Germany
Harvard School of Public Health (HSPH)
Bill and Melinda Gates Foundation; St. John's Research Institute; Karnataka Health... and other collaborators

Completed

A Skills and Drills Intervention for Emergency Obstetrics and Neonatal Care at First Referral Units of North Karnataka

Sepsis | Postpartum Hemorrhage | Birth Asphyxia | Preeclampsia/Eclampsia | Obstetric and Perinatal Complications | Obstructed/Prolonged Labor
Bioprojet

Terminated

First-time-in-man, to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BP1.5375

Healthy Male Volunteers

Netherlands
Washington University School of Medicine
Northwestern University; University of Oklahoma

Completed

Comparison of Double Wire Technique With Pancreatic Duct Stent Placement for Difficult Bile Duct Cannulation

Endoscopic Retrograde Cholangiopancreatography (ERCP) | Bile Duct Cannulation

United States
University of Aarhus
Aarhus University Hospital; University of Copenhagen; Lundbeck Foundation; Vejle... and other collaborators

Completed

Baseline Physiology Studies in Carriers of Gene Variant X Conferring Major Risk of CVD-prone Metabolic Disorders

Obesity | Diabetes Mellitus | Metabolic Syndrome | Hyperlipidemia | Arterial Hypertension

Denmark
Beijing Bio-Fortune Ltd.

Completed

Recombinant Human Serum Albumin/Interferon alpha2a Fusion Protein Phase Ib Study in Chronic Hepatitis B Patients

Chronic Hepatitis B

China

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