Search clinical trials for: Gene modified T cels

Total 497453 results

Eli Lilly and Company

Completed

A Study of Mirikizumab (LY3074828) in Participants With Crohn's Disease (VIVID-1)

Crohn's Disease

China, United States, Spain, Australia, Austria, Belgium, India, Japan, Korea, Republic of, Israel, Russian Federation, Canada, Hungary, Poland, Italy, Turkey, Switzerland, Germany, Brazil, Argentina, Latvia, Romania, Slovakia, Ukraine, Denmar... and more
National Institute of Allergy and Infectious Diseases...
London School of Hygiene and Tropical Medicine; Institut National de la Santé... and other collaborators

Active, not recruiting

Partnership for Research on Ebola VACcinations (PREVAC)

Ebola Virus Disease

Guinea, Liberia, Mali, Sierra Leone
Minneapolis Veterans Affairs Medical Center
United States Department of Defense

Completed

Gulf War Illness Inflammation Reduction Trial (GWIIRT)

Fatigue | Chronic Pain | Cognitive Impairment | Chronic Inflammation

United States
Huashan Hospital
Shanghai 10th People's Hospital; Shanghai East Hospital; Zhejiang University; The... and other collaborators

Completed

CHinese Acute Tissue-Based Imaging Selection for Lysis In Stroke -Tenecteplase II (CHABLIS-T II)

Stroke

China
Memorial Sloan Kettering Cancer Center

Active, not recruiting

In Vitro Expanded Allogeneic Epstein-Barr Virus Specific Cytotoxic T-Lymphocytes (EBV-CTLs) Genetically Targeted to the CD19 Antigen in B-cell Malignancies

Lymphoma | Acute Lymphocytic Leukemia

United States
Dr. Lutfi Kirdar Kartal Training and Research Hospital

Enrolling by invitation

Efficacy of Modified Thoracoabdominal Nerves Block Through Perichondrial Approach in Total Laparoscopic Hysterectomies

Postoperative Pain

Turkey
University Health Network, Toronto
Pancreatic Cancer Canada

Active, not recruiting

GATA6 Expression as a Predictor of Response to Peri-Operative Chemotherapy in Resectable Pancreatic Adenocarcinoma (NeoPancOne)

Resectable Pancreatic Cancer

Canada
Rajavithi Hospital

Completed

The Effect of Postoperative Modified Trendelenburg Position to Decrease Shoulder Pain After Laparoscopic Hysterectomy: A Randomized Controlled Trial

Shoulder Pain | Post Operative Pain | Gynecologic Disease

Thailand
Odense University Hospital
Danish Cancer Society; University of Southern Denmark; Academy of Geriatric Cancer...

Completed

Geriatric Oncology Screening of Older Patients With Solid Cancers (PROGNOSIS-G8)

Cancer | Frailty | Geriatrics | Solid Carcinoma | Age | Screening

Denmark
Riphah International University

Completed

Comparative Effects of Modified Cervical Retraction and Motor Control Therapeutics Exercises in Cervical Spondylosis

Cervical Spondylosis

Pakistan
University of Naples

Completed

Efficacy of Riboflavin-Enhanced Hyaluronic Acid Eye Drops in Treating Dry Eye Disease

Dry Eye Disease

Italy
Huazhong University of Science and Technology

Withdrawn

QLESP Block in Hip Surgery

Postoperative Pain

China
Octapharma

Completed

Study to Monitor Subcutaneous Human Immunoglobulin Administered at Modified Dosing Regimens in Patients With Primary Immunodeficiency Diseases

Primary Immune Deficiency Disorder

United States
University Hospital of North Norway

Completed

Laparoscopic High-Ligation Repair of Indirect Inguinal Hernias in Adults

Recurrence | Postoperative Pain | Surgery | Inguinal Hernia, Indirect
Mansoura University

Completed

Comparing a Modified Mini-incision Approach Versus the Conventional Approach for Carpal Tunnel Release

Carpal Tunnel Syndrome | Incision

Egypt
Ottawa Hospital Research Institute
The Hospital for Sick Children; Hopital Montfort; Unity Health Toronto; The Ottawa... and other collaborators

Enrolling by invitation

Clinical Surveillance Tool to Screen for Unmet Palliative Needs Among Patients in the Final Year of Life (HOMR)

Implementation Science | Screening | Terminal Care | Palliative Therapy

Canada
UNION therapeutics

Active, not recruiting

Study to Assess the Efficacy and Safety of Orismilast in Atopic Dermatitis (ADESOS)

Skin Diseases | Atopic Dermatitis

Poland, United States, Hungary, Germany
Riphah International University

Completed

Effects of Short-intensity Modified Constraint-induced Movement Therapy on Hand Function in Stroke Patients.

Ischemic Stroke | Rehabilitation | Hemorrhagic Stroke

Pakistan
Assistance Publique - Hôpitaux de Paris

Active, not recruiting

Follow-up of People at Risk of Monkeypox Infection: a Prospective Cohort Study (MonkeyVax)

Monkey Pox | Monkey Diseases

France
Zuhal Şevval Gökdere
Tokat State Hospital

Completed

Different Treatment Methods Effect on Upper Extremity Spasticity and Decreased Functionality After Stroke

Stroke | Limitation, Mobility | Spasticity as Sequela of Stroke

Turkey
M.D. Anderson Cancer Center

Completed

Modified T Cells, Chemotherapy, and Aldesleukin With or Without LV305 and CMB305 in Treating Participants With Advanced or Recurrent Sarcoma

Recurrent Synovial Sarcoma | HLA-A*0201 Positive Cells Present | NY-ESO-1 Positive Tumor Cells Present | Recurrent Myxoid Liposarcoma

United States
Janssen Vaccines & Prevention B.V.
London School of Hygiene and Tropical Medicine; Institut National de la Santé... and other collaborators

Completed

A Study of 2-dose Vaccination Regimen of Ad26.ZEBOV and MVA-BN-Filo in Infants

Ebola Virus Disease

Guinea, Sierra Leone
Federal University of São Paulo
Universidade Federal do Amazonas; PPSUS (Programa Pesquisa para o SUS: gestão... and other collaborators

Completed

Low Dose Calcium to Prevent Preeclampsia (AMCAL)

Pre-Eclampsia | Hypertension, Pregnancy-Induced | Dietary Calcium Deficiency

Brazil
University of Montana

Completed

Dynamic Assessment of Phonological Disorders

Speech Sound Disorder
Affiliated Hospital of Guangdong Medical University

Enrolling by invitation

Modified vs Conventional Blumgart Anastomosis of LPD for the Effects of Pancreatic Fistula of Periampullary Carcinoma

Bile Duct Cancer | Pancreas Cancer | Ampullary Cancer | Duodenum Cancer

China
Mansoura University

Enrolling by invitation

Comparing Two Different Tunneling Technique for Gingival Recession Treatment Using Two Different Matertial

Gingival Recession, Localized

Egypt
Kocaeli University

Completed

Evaluation of the Modified Early Warning Scoring System

Postoperative Complications | Nurse's Role | Clinical Deterioration

Turkey
Sanofi Pasteur, a Sanofi Company

Completed

Study of a Quadrivalent High-Dose Influenza Vaccine and a Moderna COVID-19 Vaccine Administered Either Concomitantly or Singly in Participants 65 Years of Age and Older Previously Vaccinated With a 2-dose Schedule of Moderna COVID-19 Vaccine

Healthy Volunteers | Influenza Immunization

United States
Bellicum Pharmaceuticals

Terminated

Safety Study of Gene Modified Donor T-cells Following TCRαβ+ Depleted Stem Cell Transplant

Lymphoma, Non-Hodgkin | Acute Lymphoblastic Leukemia | Primary Immunodeficiency | Anemia, Sickle Cell | Hemoglobinopathies | Fanconi Anemia | Anemia, Aplastic | Myelodysplastic Syndrome | Thalassemia | Cytopenia | Diamond Blackfan Anemia | Osteopetrosis | Leukemia, Acute Myeloid (AML), Child

United Kingdom, Italy
Johns Hopkins University

Completed

The Effect of Cold Storage Solutions on Ischemic Injury in Lung Transplantation

Lung Transplant Recipients
Benskin, Linda, PhD, RN, SRN (Ghana), CWCN, CWS...
The University of The West Indies; University Hospital of the West Indies; Wound... and other collaborators

Completed

Test of the Safety, Effectiveness, & Acceptability of An Improvised Dressing for Sickle Cell Leg Ulcers in the Tropics (SCLUJamaica)

Sickle Cell Leg Ulcer

Jamaica
Bavarian Nordic

Completed

MVA-BN-RSV Vaccine Trial

Respiratory Syncytial Virus Infections

United States, Germany
Bellicum Pharmaceuticals

Terminated

Long Term Follow-up Study for Patients Enrolled on the BP-004 Clinical Study

Lymphoma, Non-Hodgkin | Myelodysplastic Syndromes | Acute Lymphoblastic Leukemia | Primary Immunodeficiency | Anemia, Sickle Cell | Hemoglobinopathies | Fanconi Anemia | Anemia, Aplastic | Thalassemia | Cytopenia | Diamond Blackfan Anemia | Leukemia, Acute Myeloid (AML), Child

Italy
Daniel Benjamin
National Center for Advancing Translational Sciences (NCATS); Biomedical Advanced...

Completed

Immune Modulators for Treating COVID-19 (ACTIV-1 IM)

Covid19

United States, Brazil, Argentina, Mexico, Peru
University of California, Los Angeles

Withdrawn

Nanodiamond-Gutta Percha Composite Biomaterials for Root Canal Therapy (NDGX)

Dental Pulp Diseases | Dental Pulp Necrosis | Nerve Root Pain Nec

United States
Janssen Research & Development, LLC

Terminated

Study to Evaluate Safety and Antiviral Activity of Doses of JNJ-53718678 in Children (>=28 Days to <=3 Years) With Respiratory Syncytial Virus Infection

Respiratory Syncytial Virus Infections

United States, Taiwan, Belgium, Hungary, Thailand, United Kingdom, Germany, Korea, Republic of, Bulgaria, Turkey, France, Italy, Poland, Spain, Brazil, Russian Federation, Japan, Argentina, Malaysia, Mexico, Sweden, South Africa
Guy's and St Thomas' NHS Foundation Trust

Completed

Mindfulness Based Cognitive Therapy Modified for Visual Symptoms (MBCT-vision) (MBCT-vision)

Visual Snow Syndrome | Photophobia | Trailing Phenomenon | Visual Aura

United Kingdom
Gulhane Training and Research Hospital

Enrolling by invitation

Modified Thoracoabdominal Nerve Block(M-TAPA) in Pediatric Laparoscopic Appendectomies (M-TAPA)

Laparoscopic Surgery | Post Operative Pain | Pediatrics | Regional Anesthesia | Local Anesthetic

Turkey
Aseer Central Hospital
Armed Force Hospital Southern Region-Khamis Mushayt (AFHSR-KM); King Khalid...

Completed

Prognostic Accuracy of qSOFA, SIRS, and EWSs for In-hospital Mortality in Emergency Department (PASSEM)

Sepsis | Septic Shock

Qatar, United Arab Emirates, Turkey, Bahrain, Kuwait, Oman, Saudi Arabia
Odense University Hospital

Active, not recruiting

Optimal Predilatation Treatment Before Implantation of a Magmaris Bioresorbable Scaffold in Coronary Artery Stenosis (OPTIMIS)

Myocardial Infarction | Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Coronary Artery Disease | Coronary Disease | Arterial Occlusive Diseases | Stable Angina | Coronary Artery Stenosis | Atherosclerosis of Artery

Denmark
Nektar Therapeutics
Eli Lilly and Company

Terminated

A Study of LY3471851 in Adult Participants With Moderately to Severely Active Ulcerative Colitis (UC) (INSTRUCT-UC)

Colitis, Ulcerative

Australia, India, United States, Korea, Republic of, Hungary, United Kingdom, Japan, Argentina, Belgium, Brazil, Canada, China, Czechia, France, Georgia, Israel, Latvia, Poland, Romania, Russian Federation, Slovakia, Ukraine
Memorial Sloan Kettering Cancer Center
Stanford University; Juno Therapeutics, Inc.

Active, not recruiting

Cyclophosphamide Followed by Intravenous and Intraperitoneal Infusion of Autologous T Cells Genetically Engineered to Secrete IL-12 and to Target the MUC16ecto Antigen in Patients With Recurrent MUC16ecto+ Solid Tumors

Solid Tumors

United States
Health Education Research Foundation (HERF)

Completed

Effects of Classic and Modified CIMT on Quality of Life of Children With Hemiplegic CP (CIMT)

Hemiplegic Cerebral Palsy

Pakistan
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Genetically Modified Therapeutic Autologous Lymphocytes Followed by Aldesleukin in Treating Patients With Stage III or Metastatic Melanoma

Metastatic Melanoma | Stage III Cutaneous Melanoma AJCC v7 | Stage IV Cutaneous Melanoma AJCC v6 and v7

United States
Guna S.p.a

Terminated

Evaluation of the Efficacy of the Use MD Tissue Collagen Medical Device in the Infiltrative Treatment of Greater Trochanter Pain Syndrome (GTPS) (MEDANTRO)

Greater Trochanteric Pain Syndrome | Pertrochanteric Fracture | Gluteal Tendinitis | GTPS - Greater Trochanteric Pain Syndrome | Tendon Disorder | Gluteal Muscles

Italy
Chang Gung Memorial Hospital
National Science Council, Taiwan

Completed

A Randomized Controlled Trial of ride-on Car Training and Locomotor Experience in Toddlers With Different Motor Delays

Mobility Limitation

Taiwan
University of Sao Paulo General Hospital

Completed

Aerobic and Respiratory Exercises on Asthma

Asthma

Brazil
Biokosmes Srl
Opera CRO, a TIGERMED Group Company

Completed

Open-label Trial Evaluating Four Oral Hygiene Regimens Using a Manual Toothbrush, Toothpaste, and Mouthwash

Oral Hygiene | Dental Plaque | Toothbrushing

Italy
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Modified Immune Cells (CD19-CD22 CAR T Cells) in Treating Patients With Recurrent or Refractory CD19 Positive, CD22 Positive Leukemia or Lymphoma

Progressive Disease | Recurrent B Acute Lymphoblastic Leukemia | Refractory B Acute Lymphoblastic Leukemia | Refractory Chronic Lymphocytic Leukemia | Recurrent Non-Hodgkin Lymphoma | Refractory Non-Hodgkin Lymphoma | Minimal Residual Disease | Recurrent Chronic Lymphocytic Leukemia | CD19 Positive | CD22...

United States
St. Jude Children's Research Hospital

Active, not recruiting

Haploidentical HCT for Severe Aplastic Anemia

Aplastic Anemia | Bone Marrow Failure Syndrome

United States

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