Search clinical trials for: Middle Aged Adults

Total 18421 results

University of Witwatersrand, South Africa
GlaxoSmithKline; University of Oxford; Medical Research Council, South Africa; University...

Completed

Determinants of Type 2 Diabetes Risk in Middle-aged Black South African Men and Women

Diabetes Mellitus, Type 2 | Insulin Resistance | Menopause | Hiv

South Africa
Sanofi

Completed

Immunogenicity and Safety of Three Formulations of Dengue Vaccines in Healthy Adults Aged 18 to 45 Years in the US

Dengue Fever | Dengue Hemorrhagic Fever | Dengue Virus

United States
Lund University
Skane University Hospital

Completed

The Swedish Spinal Cord Injury Study on Cardiopulmonary and Autonomic Impairment (SPICA)

Cardiovascular Diseases | Spinal Cord Injuries | Pulmonary Disease | Autonomic Dysfunction

Sweden
University of Nottingham
University of Birmingham

Unknown

The Effect of Very Low Calorie Diet With and Without Exercise on Muscle Synthesis in Middle-aged Overweight Male. (VLCDex)

Overweight and Obesity

United Kingdom
University of Alabama at Birmingham

Completed

A Resilience Building Intervention to Promote Successful Aging (RISE)

Community Dwelling Adults Aged 50 and Older

United States
University of Sao Paulo General Hospital

Unknown

Electroacupuncture Frequency-related Effects on Non-specific Low Back Pain in Older Adults.

Low Back Pain

Brazil
Pfizer

Completed

Evaluation of a Single Vaccination With One of Three Ascending Dose Levels of a 4-Antigen Staphylococcus Aureus Vaccine (SA4Ag) in Healthy Adults Aged 18 to <65 Years

Staphylococcal Infections

United States
Pfizer

Completed

Evaluation of a Single Vaccination of One of Three Ascending Dose Levels of a 4-Antigen Staphylococcus Aureus Vaccine (SA4Ag) and a Single Dose Level of a 3-Antigen Staphylococcus Aureus Vaccine (SA3Ag) in Healthy Adults Aged 65 to <86 Years

Staphylococcal Infections

United States
Janssen Vaccines & Prevention B.V.

Completed

A Study to Evaluate the Safety, Tolerability and Immunogenicity of Two Vaccinations of Ad26.RSV.preF One Year Apart in Adults Aged 60 Years and Older in Stable Health

Healthy

United States
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Use of Oseltamivir for the Treatment of Influenza in Adults

Influenza, Human

United States, Thailand, Argentina
National Institute of Allergy and Infectious Diseases...

Completed

Comparing the Efficacy, Safety, and Tolerability of Combination Antivirals (Amantadine, Ribavirin, Oseltamivir) Versus Oseltamivir for the Treatment of Influenza in Adults at Risk for Complications (IRC003)

Influenza

United States, Australia, Argentina, Mexico, Thailand
Northumbria University
Mibelle AG

Completed

Cognitive and Cerebral Blood Flow Effects of Zanthozylum Armatum Fruit Extract in Healthy Adults Aged 30 - 55

Cognitive Change

United Kingdom
Tehran University of Medical Sciences
University of Birmingham; Golestan University of Medical Science

Completed

Prevention of Cardiovascular Disease in Middle-aged and Elderly Iranians Using a Single PolyPill (PolyIran)

Cardiovascular Diseases

Iran, Islamic Republic of
AHMED ABDULQADER HAMMOUDA ABOU SHALL
Assiut University; Kuwait University

Unknown

Study of The Association of Mutations in The NPHS2 Gene and Nephrotic Syndrome in Children and Adults in Middle East

Nephrotic Syndrome

Kuwait
Genentech, Inc.

Completed

A Study of MHAA4549A as Monotherapy for Acute Uncomplicated Seasonal Influenza A in Otherwise Healthy Adults

Influenza A

United States, Spain, Korea, Republic of, United Kingdom, Canada, New Zealand, South Africa
Hoffmann-La Roche

Terminated

A Study to Evaluate the Safety and Efficacy of Basmisanil in Adults With Severe Motor Impairment Following an Ischemic Stroke

Stroke

Spain, France
Pfizer

Completed

A Study To Investigate A Clostridium Difficile Vaccine In Healthy Adults Aged 50 To 85 Years, Who Will Each Receive 3 Doses Of Vaccine.

Clostridium Difficile

United States, Canada
University of Colorado, Denver
Centers for Disease Control and Prevention; University of Utah; Colorado Department... and other collaborators

Completed

Marketing Fall Prevention Classes to Older Adults in Faith-Based Congregations

Accidental Falls

United States
Gilead Sciences

Terminated

Efficacy and Safety of Idelalisib in Combination With Bendamustine and Rituximab in Adults With Previously Untreated Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

United States, Canada, Spain, Australia, Italy, United Kingdom, Belgium, Croatia, France, Hungary, Poland, Romania, Czechia
GlaxoSmithKline

Completed

Safety and Immunogenicity Study of GSK Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine GSK1437173A When Administered Subcutaneously Intramuscularly in Adults Aged ≥50 Years

Herpes Zoster

Japan
Central South University

Unknown

'Mindfulness-Based Joyful Sleep' Intervention in Young and Middle-aged Individuals With Insomnia

Insomnia

China
Gilead Sciences

Completed

Efficacy, Pharmacokinetics, and Safety of Presatovir in Hospitalized Adults With Respiratory Syncytial Virus (RSV) Infection

Respiratory Syncytial Virus Infection

Korea, Republic of, Australia, Israel, New Zealand, Netherlands, United States, France, United Kingdom, Italy, Belgium, Poland
GlaxoSmithKline

Completed

Immunogenicity & Safety of GSK's Avian Flu Vaccine 1557484A Given to Adults Aged 18-64 Years

Influenza

United States, Canada
Otsuka Pharmaceutical Development & Commercialization...

Completed

Safety and Tolerability of Oral OPC-34712 as Adjunctive Therapy in Adults With Major Depressive Disorder (the Orion Trial) (Orion)

Mental Disorders | Depressive Disorder | Depression | Mood Disorders | Depressive Disorder, Major

United States, France, Poland, Russian Federation, Romania, Ukraine, Germany, Hungary, Slovakia, Serbia, Canada
Pfizer

Completed

A Phase 1, Randomized, Controlled, Observer-blinded Trial to Evaluate the Safety and Immunogenicity of a Multivalent Pneumococcal Conjugate Vaccine in Healthy Adults Aged 18 to 49 Years

Pneumococcal Infections

United States
GlaxoSmithKline

Completed

A Study of Immunogenicity and Safety of GSK Biologicals' Influenza Vaccine FLU-Q-QIV in Adults Aged 18 Years and Older

Influenza

Canada
GlaxoSmithKline

Completed

Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Trivalent Split Virion Influenza Vaccine Fluviral™ (2013-2014 Season) in Adults Aged 18 Years and Older

Influenza

Canada
GlaxoSmithKline

Completed

A Study for Evaluation of Immunogenicity and Reactogenicity of Fluarix/Influsplit SSW 2012/2013 in People Aged 18 Years and Above

Influenza

Germany
VA Office of Research and Development
Duke University

Completed

Physical Activity for Older Adults Chronic Low Back Pain (PACe-LBP)

Low Back Pain

United States
LHL Helse

Completed

Cardiac Screening of Middle Aged and Older Women and Men (Master Athletes) (MASTERSCREEN)

Heart Disease

Norway
AstraZeneca

Completed

A Phase 3 Study to Evaluate the Efficacy and Safety of Tralokinumab in Adults and Adolescents With Uncontrolled Asthma (STRATOS1)

Uncontrolled Asthma

United States, Belgium, Poland, Taiwan, Vietnam, Korea, Republic of, Peru, Slovakia, Argentina, Germany, Ukraine, Bulgaria, Hungary, Spain, Colombia
Örebro University, Sweden
Fibebiotics consortium (EU)

Completed

Prebiotic Supplementation and Intestinal Barrier Function in Elderly: a RCT

Aged | Prebiotics

Sweden
University of Copenhagen
Rigshospitalet, Denmark; Glostrup University Hospital, Copenhagen

Completed

Effects of Exercise Training on Cardiovascular Health in Middle-aged Women

Cardiovascular Diseases | Metabolic Diseases | Blood Platelet Disorders | Menopause | Cardiac Function Impaired

Denmark
GlaxoSmithKline

Completed

Safety and Immunogenicity of GSK's Tdap Vaccine (Boostrix) in Adults Aged 19 to 64 Years

Tetanus | Diphtheria | Acellular Pertussis

United States
Anabela Correia Martins
Sensing Future Technologies; Fraunhofer Portugal Research Center for Assistive...

Completed

FallSensing, a Multifactorial Screening Tool for Fall-risk in Community-dwelling Adults Aged 50 Years or Over

Accidental Falls
GlaxoSmithKline

Completed

An Efficacy and Safety Study of Fluticasone Furoate/Vilanterol 100/25 Microgram (mcg) Inhalation Powder, Fluticasone Propionate/Salmeterol 250/50 mcg Inhalation Powder, and Fluticasone Propionate 250 mcg Inhalation Powder in Adults and Adolescents With Persistent Asthma

Asthma

United States, Argentina, Germany, Korea, Republic of, Romania, Russian Federation, Spain, Netherlands, Mexico, Brazil, Chile, Czechia
GlaxoSmithKline
Parexel

Completed

SAS115359: A 6-month Study to Assess the Safety and Benefit of Inhaled Fluticasone Propionate/Salmeterol Combination Compared With Inhaled Fluticasone Propionate in the Treatment of Adolescents and Adults (12 Years of Age and Older) With Asthma. (AUSTRI)

Asthma

United States, Australia, Poland, Russian Federation, Spain, Ukraine, Germany, Bulgaria, Argentina, Peru, South Africa, Taiwan, Belgium, Italy, Hungary, Korea, Republic of, Austria, Romania, Colombia, Slovakia, United Kingdom, Mexico and more
Cerebos Pacific Limited

Unknown

CMI-168 on Cognitive Function in Healthy Middle-aged Men and Women

Cognitive Change

Taiwan
UCB Pharma

Completed

A Multi-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Certolizumab Pegol in Combination With Methotrexate in the Treatment of Disease Modifying Antirheumatic Drugs (DMARD)-naïve Adults With Early Active Rheumatoid Arthritis (C-early)

Rheumatoid Arthritis

Germany, United States, Argentina, Australia, Austria, Belgium, Canada, Colombia, Czechia, France, Hungary, Ireland, Italy, Mexico, Monaco, Netherlands, Poland, Romania, Spain, Sweden, Switzerland, United Kingdom
UCB Pharma SA

Completed

A Multi-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Certolizumab Pegol in Combination With Methotrexate in the Treatment of Disease Modifying Antirheumatic Drugs (DMARD)-naïve Adults With Early Active Rheumatoid Arthritis (C-early)

Rheumatoid Arthritis

Germany, United States, Argentina, Australia, Austria, Belgium, Canada, Colombia, Czechia, France, Hungary, Ireland, Italy, Mexico, Monaco, Netherlands, Poland, Romania, Spain, Sweden, Switzerland, United Kingdom
GlaxoSmithKline

Completed

A Trial to Test the Response to Different Vaccination Regimens With an H5N1 Vaccine With AS03 in Adults Aged 18-64

Influenza

Canada
GlaxoSmithKline

Completed

Study to Evaluate the Safety and Immunogenicity of a Pandemic Influenza Vaccine in Adults Aged 18 Years and Above

Influenza

France, Spain, Germany, Russian Federation, Estonia, Sweden, Netherlands
Anabela Correia Martins
Sensing Future Technologies; Fraunhofer Portugal Research Center for Assistive...

Unknown

FallSensing Clinical Tool for Fall Risk Prevention in Community-dwelling Adults Aged 50 Years or Over

Accidental Falls

Portugal
GlaxoSmithKline

Completed

Immunogenicity & Safety of GSK's Avian Flu Vaccine 1557484A Given to Adults Aged ≥18 Years

Influenza

United States, Canada
National Institute of Allergy and Infectious Diseases...
Naval Medical Research Center; SAb Biotherapeutics, Inc.

Completed

Safety, Tolerability, and Pharmacokinetics of SAB-301 in Healthy Adults

Middle East Respiratory Syndrome Coronavirus

United States
GlaxoSmithKline

Completed

Non-Inferiority of Various GSK Bio's Influenza Vaccine Presentations in Adults Aged 65 Years and Over

Influenza

Norway, Estonia, Denmark
GlaxoSmithKline

Completed

Immunogenicity & Safety of GSK's Influenza Vaccine 1557484A Given to Adults Aged ≥18 Years

Influenza

United States, Canada
GlaxoSmithKline

Completed

Immunogenicity & Safety Study of Fluviral® (2010 - 2011 Season) in Adults Aged 18 to 60 Years and Over 60 Years

Influenza

Canada
GlaxoSmithKline

Completed

Immunogenicity and Safety of Meningococcal Vaccine GSK134612 vs. Menactra® in Healthy Adolescent/Adults Aged 10-25 Years.

Infections, Meningococcal

United States
GlaxoSmithKline

Completed

Study to Assess the Safety and Immunogenicity of GlaxoSmithKline (GSK) Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine in Adults Aged 18 Years and Older With Blood Cancers

Herpes Zoster

France, Spain, Taiwan, Belgium, Singapore, United States, Hong Kong, Russian Federation, Finland, Korea, Republic of, Czechia, Australia, Canada, Sweden, Poland, United Kingdom, Panama, Italy, Turkey, Pakistan, New Zealand

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