Search clinical trials for: Ophthalmology

Total 1399 results

Rigshospitalet, Denmark

Active, not recruiting

Steroids and/ or Non-steroidal Anti-inflammatory Drugs in the Postoperative Regime After Trabeculectomy. (SNAP)

Glaucoma

Denmark
InnFocus Inc.

Completed

InnFocus MicroShunt Versus Trabeculectomy Study (IMS)

Primary Open Angle Glaucoma

Spain, United States, United Kingdom, France, Netherlands, Italy
Noveome Biotherapeutics, formerly Stemnion
IQVIA Biotech

Terminated

ST266 Eyedrops for the Treatment of Persistent Corneal Epithelial Defects

Persistent Corneal Epithelial Defect

United States
Loma Linda University

Completed

Use of Ocular Point of Care Ultrasound in Diagnosing Retinal Detachment in the Emergency Department (RDOcularUS)

Retinal Detachment

United States
Vienna Institute for Research in Ocular Surgery

Completed

Predicting the Lens Capsular Bag Size Using Pre-operative Biometry

Cataract Senile

Austria
Research Institute of Ophthalmology, Egypt

Completed

Assessing the Atraumatic Technique in Ophthalmic Patients

Intravenous Cannula Regional Ophthalmic Anesthesia

Egypt
Hoffmann-La Roche

Completed

A Phase III Study to Evaluate the Port Delivery System With Ranibizumab Compared With Monthly Ranibizumab Injections in Participants With Wet Age-Related Macular Degeneration (Archway)

Neovascular Age-Related Macular Degeneration

United States
Optos, PLC

Completed

Study Comparing the P200TE and the P200TxE in Glaucoma Patients

Glaucoma

United States
Wuerzburg University Hospital

Completed

Outflow Facility AIT vs Microshunt

Glaucoma

Germany
Immunovant Sciences GmbH

Terminated

ASCEND GO-2: Study of RVT-1401 for the Treatment of Participants With Active, Moderate to Severe Graves' Ophthalmopathy ( GO )

Graves' Ophthalmopathy (GO)

United States, Germany, Spain, Canada, Italy
Jaeb Center for Health Research
National Eye Institute (NEI); National Institutes of Health (NIH)

Completed

Effects of Pneumatic Vitreolysis on Vitreomacular Traction (AG)

Vitreomacular Traction

United States
Jaeb Center for Health Research
National Eye Institute (NEI); National Institutes of Health (NIH)

Completed

Effects of Pneumatic Vitreolysis on Macular Hole (Protocol AH)

Vitreomacular Traction (VMT) | Full-thickness Macular Holes (MH)

United States
Jaeb Center for Health Research
Juvenile Diabetes Research Foundation; National Eye Institute (NEI); National... and other collaborators

Completed

A Pilot Study Evaluating Photobiomodulation Therapy for Diabetic Macular Edema (AE)

Diabetic Macular Edema

United States
Research Institute of Ophthalmology, Egypt

Completed

Lidocaine Gel 2% and Muscle Traction Pain During Squint Surgery in Pediatrics

Squint

Egypt
Hoffmann-La Roche

Completed

A Study to Evaluate the Efficacy and Safety of Faricimab (RO6867461) in Participants With Diabetic Macular Edema (YOSEMITE)

Diabetic Macular Edema

United States, Japan, Israel, Austria, France, Germany, Hungary, Italy, Mexico, Poland, Slovakia, Spain, Russian Federation, Bulgaria, Turkey, Peru
Aerie Pharmaceuticals

Completed

A Phase 2 Study Evaluating the Safety and Efficacy of Netarsudil Ophthalmic Solution in Patients With Corneal Edema Due to Fuchs Corneal Dystrophy (Fuchs)

Corneal Edema

United States
Sight Sciences, Inc.

Active, not recruiting

Prospective, Randomized, Masked, Controlled Trial To Evaluate The Safety And Effectiveness Of The TearCare® System In The Treatment Of The Signs And Symptoms Of Dry Eye Disease (SAHARA)

Dry Eye | Meibomian Gland Dysfunction

United States
Research Institute of Ophthalmology, Egypt

Completed

Bupivacaine vs Oxybuprocaine Topical Anesthesia in IVI

Pain, Acute

Egypt
Glaukos Corporation

Terminated

iStent Inject in OAG Subjects on 2 Pre-op Topical Ocular Hypotensive Medications

Primary Open Angle Glaucoma (POAG)

Brazil
Glaukos Corporation

Completed

Prospective Evaluation of Open-angle Glaucoma Subjects on Two Topical Hypotensive Medication Treated With Two iStents

Subjects With Primary Open-angle Glaucoma (POAG)

Armenia
Nantes University Hospital

Completed

Efficacy and Tolerance Comparison Between Subconjunctival Injection of Triamcinolone and Intravitreal Implant of Dexamethasone for the Treatment of Inflammatory Macular Edema (TRIOZ)

Inflammatory Macular Edema

France
Glaukos Corporation

Completed

A Prospective Evaluation of Open-Angle Glaucoma Subjects on Two Topical Hypotensive Medications Treated With One Suprachoroidal Stent

Subject With Primary Open-angle Glaucoma (POAG)

Armenia
Universitaire Ziekenhuizen KU Leuven

Active, not recruiting

Confounding Factors in Ocular Surface Microbiome Research (CoFa)

Ocular Surface Microbiome

Belgium
Silk Technologies, Ltd.

Completed

Study to Evaluate the Safety and Efficacy of SDP-4 in Subjects With Dry Eye Disease (DED) (SDP-4-CS201)

Dry Eye

United States
Silk Technologies, Ltd.

Completed

Study to Evaluate the Efficacy of SDP-4 in Subjects With Dry Eye Disease (DED) (SDP-4-CS202)

Dry Eye

United States
Glaukos Corporation

Completed

Purpose of This Study is to Evaluate the Safety and Efficacy of One, Two, or Three iStents for the Reduction of Intraocular Pressure in Open-angle Glaucoma Subjects

Primary Open Angle Glaucoma (POAG)

Armenia
Glaukos Corporation

Completed

One, Two, or Three iStents for the Reduction of Intraocular Pressure in Open-angle Glaucoma Subjects

Primary Open Angle Glaucoma (POAG)

Armenia
Wenzhou Medical University

Completed

Color Doppler Ultrasound in Lacrimal Sac Space-occupying Lesions

Computed Tomography | Dacryocystitis; Chronic | Lacrimal Sac Space-occupying Lesions | Color Doppler Ultrasound

China
Technische Universität Dresden
Fraunhofer Institute for Ceramic Technologies and Systems IKTS

Completed

Computer-aided Diagnosis of Ocular Diseases Based on Corneal Biomechanics (EyeTwin)

Glaucoma | Corneal Astigmatism | Keratoconus | Open Angle Glaucoma | Corneal Ectasia | Corneal Disease | Normal Tension Glaucoma

Germany
Faculty Hospital Kralovske Vinohrady

Withdrawn

Brolucizumab vs. Aflibercept for Retinal Angiomatous Proliferation (BEY-RAP)

Wet Macular Degeneration

Czechia
GenSight Biologics

Completed

Efficacy Study of GS010 for the Treatment of Vision Loss up to 6 Months From Onset in LHON Due to the ND4 Mutation (RESCUE)

Optic, Atrophy, Hereditary, Leber

United Kingdom, United States, France, Germany, Italy
Universitaire Ziekenhuizen KU Leuven

Completed

Optimization of Sampling and Processing of Samples for Molecular Microbial Research on Ocular Surface Samples (EPSO)

Microbiota | Ocular Surface

Belgium
Aristotle University Of Thessaloniki

Completed

From Preserved, to Preservative-free Cyclosporine 0.1% Enhanced Triple Glaucoma Therapy

Glaucoma | Ocular Surface Disease

Greece
Neurotech Pharmaceuticals

Terminated

Study of the Intravitreal Implantation of NT-503-3 Encapsulated Cell Technology (ECT) for the Treatment of Recurrent Choroidal Neovascularization (CNV) Secondary to Age-related Macular Degeneration (AMD)

Macular Degeneration

United States, Israel
Ocugen

Completed

Study of Brimonidine Tartrate Nanoemulsion Eye Drop Solution in the Treatment of Dry Eye Disease (DED)

Dry Eye

United States
Stanford University
National Eye Institute (NEI); Bausch & Lomb Incorporated; Alcon Research; BSN-JOBST... and other collaborators

Completed

Infant Aphakia Treatment Study (IATS) (IATS)

Congenital Cataract

United States
Ocugen

Terminated

Study of Brimonidine Tartrate Nanoemulsion Eye Drops in Patients With Ocular Graft-vs-Host Disease (oGVHD)

Graft vs Host Disease | Ocular Surface Disease | Graft Versus Host Disease | Ocular Graft vs Host Disease | Ophthalmic Solutions | oGVHD | Brimonidine Tartrate | Lubricant Eye Drops

United States
Semmelweis University

Completed

Semi-manual Vessel Density Analysis on Optical Coherence Tomography Angiography Images of Healthy Adults

Healthy

Hungary
Sight Sciences, Inc.

Terminated

A Prospective, Multicenter Study of the OMNI® Surgical System in Pseudophakic Eyes With Open Angle Glaucoma (ORION)

Glaucoma, Open-Angle

United States
Jaeb Center for Health Research
Icahn School of Medicine at Mount Sinai; National Eye Institute (NEI); University...

Terminated

Surgical Idiopathic Intracranial Hypertension Treatment Trial (SIGHT)

Idiopathic Intracranial Hypertension

United States, Canada, Puerto Rico
Massachusetts General Hospital
Patient-Centered Outcomes Research Institute

Completed

An Online Health Tool About Down Syndrome: Down Syndrome Clinic to You (DSC2U)

Down Syndrome

United States
Allergan

Completed

Efficacy and Safety of a New Artificial Tear Formulation Compared With Systane Ultra Multidose in Participants With Dry Eye Disease

Dry Eye Disease (DED)

United States
Kodiak Sciences Inc

Terminated

A Study to Evaluate the Efficacy and Safety of KSI-301, an Anti-VEGF Antibody Biopolymer Conjugate, Versus Aflibercept in Patients With Neovascular (Wet) Age-Related Macular Degeneration. (DAZZLE)

Wet Macular Degeneration

Germany, United States, Latvia, Spain, Czechia, Poland, Slovakia
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Completed

Trial of Overminus Spectacle Therapy for Intermittent Exotropia (IXT5)

Intermittent Exotropia

United States, Canada
TearClear Corp

Active, not recruiting

Prospective, Double-masked, Randomized, Multi-center, Active-controlled, Parallel-group, 3-month Study Assessing the Safety & Ocular Hypotensive Efficacy of TC-002 Ophthalmic Solution Compared to Latanoprost Ophthalmic Solution 0.005% in Subjects With Elevated Intraocular Pressure (TC-002-301)

Elevated Intraocular Pressure

United States
Frank G. Holz
Radboud University Medical Center; Bayer; Hoffmann-La Roche; Novartis Pharmaceuticals and other collaborators

Active, not recruiting

Development of Novel Clinical Endpoints in Intermediate AMD (MACUSTAR)

Age Related Macular Degeneration (AMD)

Germany, Italy, Netherlands, United Kingdom, France, Portugal, Denmark
Second Affiliated Hospital, School of Medicine,...

Enrolling by invitation

Study on the Effect of Eye-covering Pretreatment on Acute Delirium After General Anesthesia in Pre-school Aged Children

Ophthalmology

China
Ada Health GmbH
Muhimbili University of Health and Allied Sciences

Active, not recruiting

Clinic Waiting Room-based Study of Swahili Language Artificial Intelligence-driven Symptom Assessments in Tanzanian Primary Health Care Facilities (AFYA)

Neurological Conditions | Mental Health Conditions | Abdominal Pain/Gastrointestinal Issues | Lower Respiratory System Conditions | Upper Respiratory System Conditions | Ophthalmology Conditions | Orthopedic Conditions | Cardiovascular System Conditions | Genitourinary System Conditions | ENT Conditions | Dermatology Conditions and other conditions

Tanzania
AcuFocus, Inc.

Completed

Evaluation of Long-Term Clinical Acceptability and Satisfaction With the IC-8 Intraocular Lens

Cataract | Presbyopia

Germany, Italy, Norway, Spain
ProQR Therapeutics

Active, not recruiting

A Study to Evaluate the Safety and Tolerability of QR-1123 in Subjects With Autosomal Dominant Retinitis Pigmentosa Due to the P23H Mutation in the RHO Gene (AURORA)

Eye Diseases | Retinitis | Eye Diseases, Hereditary | Retinal Dystrophies | Vision Disorders | Retinal Disease | Autosomal Dominant Retinitis Pigmentosa | Vision Tunnel

United States

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