Search clinical trials for: Randomized Controlled Double-blind Study

Total 130619 results

Reata, a wholly owned subsidiary of Biogen

Withdrawn

A Double-Blind, Randomized, Placebo-Controlled Study Evaluating the Effects of Bardoxolone Methyl on Body Composition in Patients With Stage 4 Chronic Kidney Disease and Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2 | Renal Insufficiency, Chronic
Reata, a wholly owned subsidiary of Biogen

Withdrawn

A Double-Blind, Randomized, Placebo-Controlled Safety Study Evaluating the Effects of Residual Renal Function (RFF) in Patients With End-Stage Renal Disease and Type 2 Diabetes Mellitus on Peritoneal Dialysis

Type 2 Diabetes Mellitus | End-Stage Renal Disease
Sumitomo Pharma America, Inc.
BehaVR LLC

Completed

A Randomized, Controlled Study of Two At-Home Self-Guided Virtual Reality Interventions for Adults With Social Anxiety Disorder. (BVR-100-102)

Social Anxiety Disorder (SAD)

United States
Auerbach Hematology Oncology Associates P C
AMAG Pharmaceuticals, Inc.

Completed

Pilot Study: Randomized, Placebo-controlled Comparator Trial of IV vs Oral Iron Treatment of RLS With IDA. (IVOR-IDA)

Restless Legs Syndrome | Iron Deficiency Anemia

United States
Vastra Gotaland Region

Completed

A Randomized Controlled Study Comparing Priming Solution Containing Crystalloid or Packed Red Blood Cells in Patients Treated With Isolated Limb Perfusion. (ILP-Prime)

Melanoma | Sarcoma

Sweden
Sanofi
Regeneron Pharmaceuticals

Completed

A Phase 4, Randomized, Double-blind, Placebo-controlled,Multicenter, Parallel-group Study of the Effect of Dupilumab on Sleep Disturbance in Patients With Uncontrolled Persistent Asthma (MORPHEO)

Asthma

Spain, United States, Argentina, Canada, Germany, Italy, Netherlands, Portugal, Russian Federation, Ukraine, United Kingdom
Lykos Therapeutics

Terminated

Randomized Placebo-controlled Study of MDMA-assisted Therapy in People With PTSD - Israel

Posttraumatic Stress Disorder

Israel
Lykos Therapeutics

Completed

Randomized, Double-blind, Active Placebo-Controlled Pilot Study of MDMA-assisted Psychotherapy in People With Chronic PTSD

Posttraumatic Stress Disorder (PTSD)

Israel
Genzyme, a Sanofi Company

Active, not recruiting

A Multinational, Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy, Pharmacodynamics, Pharmacokinetics, and Safety of Venglustat in Late-onset GM2 (AMETHIST)

Tay-Sachs Disease | Sandhoff Disease

United States, Argentina, Czechia, Portugal, Russian Federation, Turkey, United Kingdom, Brazil, France, Germany, Italy, Japan, Spain
Sanofi

Completed

A Randomized Placebo- and Active Comparator-controlled Study to Evaluate the Photosafety of SAR441566

Rheumatoid Arthritis

United States
Yale University
Mayo Clinic; Duke University; National Evaluation System for health Technology...

Active, not recruiting

Heart Watch Study: a Pragmatic Randomized Controlled Trial

Atrial Fibrillation | Cardioversion

United States
University of New Mexico

Terminated

Scheduled Triple-lumen Central Venous Catheter Exchange: A Prospective Controlled Randomized Study

Cancer | Other Female Genital

United States
Assistance Publique - Hôpitaux de Paris

Completed

Efficacy of Corticosteroids to Treat Outpatients With Acute Exacerbations of COPD (BECOMEG)

Pulmonary Disease | Chronic Obstructive (MeSH)

France
Seattle Children's Hospital
University of Alabama at Birmingham; St. Jude Children's Research Hospital; Children...

Active, not recruiting

The Promoting Resilience in Stress Management (PRISM) Intervention: a Multi-site Randomized Controlled Trial for Adolescents and Young Adults Receiving Hematopoietic Cell Transplantation

Depression | Quality of Life | Cancer | Anxiety | Adherence, Medication | Coping Skills | Bone Marrow Neoplasms | Adolescent Behavior

United States
AbbVie

Completed

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of ABT-494 for the Induction of Symptomatic and Endoscopic Remission in Subjects With Moderately to Severely Active Crohn's Disease Who Have Inadequately Responded to or Are Intolerant to Immunomodulators or Anti-TNF Therapy

Crohn's Disease
The University of Hong Kong

Active, not recruiting

Full-scale Intervention Study: Genetic Risk Communication and Wearables

Physical Activity | Type 2 Diabetes | Genetic Predisposition to Disease | Exercise | Fitness Trackers

Hong Kong
University of Oxford
Bayer; Medical Research Council; Abbott; British Heart Foundation; Solvay Pharmaceuticals and other collaborators

Active, not recruiting

ASCEND: A Study of Cardiovascular Events iN Diabetes

Diabetes Mellitus

United Kingdom
Istanbul University - Cerrahpasa (IUC)

Completed

The Effect of Peer-Guided Pilates Exercise on Premenstrual Syndrome Symptoms and Healthy Lifestyle Behaviors: A Randomized Controlled Study

Premenstrual Syndrome

Turkey
Walter Reed Army Institute of Research (WRAIR)

Enrolling by invitation

A Comparison of the Physiological and Behavioral Effects of Suvorexant and Zolpidem in Healthy Volunteers: A Randomized, Double-blind, Placebo Controlled Study

Performance Enhancing Product Use

United States
University of Southern Denmark
Copenhagen University Hospital, Denmark; National Board of Health, Denmark; S... and other collaborators

Completed

Body Therapy for War Veterans With Post Traumatic Stress Disorder (PTSD)

Behavioral Symptoms | Depression | Quality of Life | Stress Disorders, Post-Traumatic | Trauma and Stressor Related Disorders

Denmark
Sunnaas Rehabilitation Hospital
Oslo University Hospital; The Research Council of Norway; Monash University; Children... and other collaborators

Completed

The Child in Context Intervention Study (CICI)

Brain Diseases | Brain Injuries | Rehabilitation | Parenting | Child Behavior | Family | Brain Injury, Chronic | Childhood Brain Tumor

Norway
Sanofi Pasteur, a Sanofi Company

Completed

A Phase I, Randomized, Modified Single-blind, Active-controlled (Infants Only), Four-stage, Step-down, Comparative, Multi-center Study

Meningococcal Immunization
MacroGenics
Eli Lilly and Company

Completed

The Protégé Study - Clinical Trial of MGA031 in Children and Adults With Recent-Onset Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

United States, Spain, Israel, Canada, India, Czechia, Ukraine, Sweden, Latvia, Mexico, Germany, Poland, Romania, Estonia, Netherlands, United Kingdom
Georgia Southern University
Indiana University; Weight Watchers International

Active, not recruiting

WW Improving Nutrition Study: A Randomized Controlled Trial (WINS)

Overweight and Obesity

United States
Chinese PLA General Hospital
Dalian Zhen-Ao Bio-Tech Co., Ltd.

Active, not recruiting

A Randomized, Single-blind, Controlled Clinical Study of Cardiomyopeptidin on Improving Ischemia-reperfusion Injury in Patients With Acute ST-segment Elevation Myocardial Infarction After Primary PCI

Cardiovascular Diseases

China
Ginekologija Dr. Franić, D.O.O.

Active, not recruiting

RF in the Treatment OAB in UUI- a Prospective Randomized Placebo Controlled Study (RFandOAB)

Urge Incontinence | Overactive Bladder Syndrome

Slovenia
Peking University
Sun Yat-sen University; Yangzhou University; Centers for Disease Control and... and other collaborators

Terminated

Chinese Heart Healthy Diet for People With High Cardiovascular Risk in China (DECIDE-Diet)

Cardiovascular Disease | Diet Modification | Randomized Controlled Trial

China
Satsuma Pharmaceuticals, Inc.

Completed

A Randomized, Double-Blind, Parallel Group, Placebo-Controlled Study to Assess STS101 in the Acute Treatment of Migraine (SUMMIT)

Migraine | Migraine Without Aura | Migraine With Aura

United States
Sheba Medical Center

Completed

Phase 3 Multicenter Randomized Double Blind Placebo Controlled Study With Antibacterial Prophylaxis in Azacitidine Treated MDS Patients

Prevention

Israel
Assistance Publique - Hôpitaux de Paris

Completed

The Evaluation of a CONSORT Based Online Writing Tool (COBWEB)

Focus of Study = Medical Writing

France
Raziel Therapeutics Ltd.

Completed

A Single Blind, Randomized, Placebo-controlled, Phase 2a, 2-cohort Study for the Evaluation of Safety and Efficacy of RZL-012 for Submental Fat Reduction in Healthy Volunteers.

Submental Fat

United States
Scynexis, Inc.

Suspended

A Phase 3, Randomized, Double-blind Study for Patients With Invasive Candidiasis Treated With IV Echinocandin Followed by Either Oral Ibrexafungerp or Oral Fluconazole (MARIO)

Candidemia | Candidiasis, Invasive

United States, Korea, Republic of, Greece, Canada, France, Belgium, Germany, Italy, Spain, South Africa, Bulgaria, Israel
University Ghent
Research Foundation Flanders

Completed

Voice Therapy With a Semi-occluded Vocal Tract

Voice Disorders

Belgium
PharmaTher Inc.

Suspended

Randomized, Double-Blind, Active Placebo-Controlled Study of Ketamine to Treat Levodopa-Induced Dyskinesia

Central Nervous System Diseases | Nervous System Diseases | Neurologic Manifestations | Movement Disorders | Dyskinesias

United States
University of Pittsburgh
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Active, not recruiting

The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes (TRIABETES)

Obesity | Type 2 Diabetes Mellitus

United States
University of Southern California
National Institute on Aging (NIA); Huntington Hospital

Completed

Social Work Intervention Focused on Transitions (SWIFT)

Depression | Stroke | Hypertension | Diabetes | Cancer | Chronic Obstructive Pulmonary Disease | Asthma | Chronic Heart Failure | Heart Disease | Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention

United States
Yung Sheng Optical Co., Ltd.

Completed

A Prospective, Randomized, Double-blind, Parallel, Active-controlled Clinical Study of Silicone Hydrogel Monthly Soft Contact Lens for the Safety and Effectiveness in Visual Correction.

Myopia

Taiwan
Oslo University Hospital
Helse Sor-Ost

Active, not recruiting

Testing the Effect of KnowMAP (Knowledge Management for Renal Transplant Recipients). A Randomized Controlled Study (KnowMAP)

Kidney Transplantation

Norway
Cinclus Pharma AG
Parexel

Completed

A Study in Patients With Erosive Esophagitis to Investigate Safety, Tolerability, and Healing Rates After 4 Weeks Treatment of X842 or Lansoprazole and Symptom Pattern During Subsequent 4 Weeks Treatment With Lansoprazole

Erosive Esophagitis

Poland, Bulgaria, Serbia, Georgia, United States, Czechia, Hungary, Ukraine
Novartis Pharmaceuticals

Completed

A Randomized, Open, Parallel, Controlled, Multi-center, Interventional, Cross-sectional Study to Evaluate the Detection Rate of Psoriatic Arthritis in Korean Moderate-to-severe Psoriasis Patients, With or Without Active Screening for Arthritis in Psoriasis (ASAP Study) (ASAP)

Psoriasis

Korea, Republic of
McMaster University
Purdue Pharma, Canada

Completed

A 14 Week, Randomized, Placebo-Controlled Cross-Over Study of Methylphenidate Hydrochloride Controlled Release Capsules in Adult ADHD With and Without Anxiety Disorder Comorbidity

Generalized Anxiety Disorder | Attention Deficit Hyperactivity Disorder | Social Anxiety Disorder | Panic Disorder | Agoraphobia

Canada
Occlutech International AB

Active, not recruiting

Flow Regulation by Opening the SepTum in Patients With Heart Failure; a Prospective, Randomized, Sham-controlled, Double-blind, Global Multicenter Study (FROST-HF)

Heart Failure With Preserved Ejection Fraction (HFpEF) | Heart Failure With Reduced Ejection Fraction (HFrEF)

United States
Sarepta Therapeutics, Inc.

Completed

A Randomized, Double-blind, Placebo-controlled Study of Delandistrogene Moxeparvovec (SRP-9001) for Duchenne Muscular Dystrophy (DMD)

Muscular Dystrophy, Duchenne

United States
Yuhan Corporation

Completed

A Randomized, Active-controlled, Parallel, Open-label, Multicenter, Phase 4 Study to Compare the Efficacy and Safety of Pregabalin Sustained Release Tablet and Pregabalin Immediate Release Capsule in Type II Diabetic Patients With Peripheral Neuropathic Pain

Diabetes Mellitus, Type 2 | Neuropathic Pain

Korea, Republic of
Poznan University of Physical Education

Completed

The Effect of a Multistrain Probiotic on Metformin Tolerance and Efficacy With Microbiota and Stool Metabolome in Insulin-resistant Women - a 12-week Randomized, Placebo-controlled, Double-blind Study

Insulin Resistance

Poland
AstraZeneca

Completed

A Study of the Safety, Tolerability and Pharmacokinetics of MEDI0618 in Healthy Volunteers

Chronic Pain

Germany
Centro de Investigación en Alimentación y Desarrollo...

Completed

Antihypertensive Effect of Fermented Milk With Lactococcus Lactis on Prehypertensive Subjects

Hypertension
Ankara University

Completed

Evaluation of the Effectiveness of Obstetric Lubricant Gel in Labor in Nulliparous and Primiparous Women: A Randomized Controlled Study

Parturition | Obstetric; Injury Pelvic Floor
Cairo University

Completed

Clinical and Radiographic Evaluation of Resin Endocrown as Long Term Interim Restoration Versus Stainless Steel Crown for Endodontically Treated First Permanent Molar in Children: Randomized Controlled Pilot Study.

Dental Caries in Children

Egypt
Universidad de Almeria

Completed

A Study Protocol Comparing a Home Rehabilitation Program Versus e-Health Program in Low Back Pain

Chronic Low-back Pain

Spain

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