Search clinical trials for: Wnt pathway

Total 1441 results

NuCana plc

Completed

A Safety, Pharmacokinetic and Efficacy Study of NUC-3373 in Combination With Standard Agents Used in Colorectal Cancer Treatment

Colorectal Neoplasms | Colorectal Cancer | Colorectal Tumors | Colorectal Carcinoma | Neoplasms, Colorectal

United States, France, United Kingdom
University of Michigan
Wayne State University; The University of Texas at Arlington

Enrolling by invitation

Evaluating a School-based Social and Material Needs Identification System to Prevent Youth Violence Involvement

Violence, Physical | Maltreatment, Child

United States
Centre Hospitalier Intercommunal de Toulon La Seyne...
French Cardiology Society

Completed

Evaluation and Support Care Process Within the Care Pathway of Heart Failure Patients (FIL-EAS)

Heart Failure Acute

France
Pfizer

Active, not recruiting

Study of the Efficacy and Safety PF-06741086 in Adult and Teenage Participants With Severe Hemophilia A or Moderately Severe to Severe Hemophilia B

Hemophilia A | Hemophilia B

United States, Spain, Canada, China, Korea, Republic of, Hong Kong, Serbia, Taiwan, Turkey, France, Oman, Saudi Arabia, Japan, India, South Africa, Mexico, Croatia, Italy, Bulgaria, Russian Federation
NHS Greater Glasgow and Clyde
University of Glasgow

Completed

Optimising a Digital Diagnostic Pathway for Heart Failure in the Community (OPERA)

Heart Failure

United Kingdom
IRCCS Eugenio Medea

Active, not recruiting

Evaluation of Brain Waste Clearance Pathways Using Magnetic Resonance Imaging in Pediatric Patients With White Matter Diseases

Pediatric Disorder | Glymphatic System | White Matter Disease | Perivascular Disease

Italy
St. Jude Children's Research Hospital
Eli Lilly and Company

Active, not recruiting

Evaluation of LY2606368 Therapy in Combination With Cyclophosphamide or Gemcitabine for Children and Adolescents With Refractory or Recurrent Group 3/Group 4 or SHH Medulloblastoma Brain Tumors

Brain Cancer | Brain Tumor | Medulloblastoma | Brain Tumor, Recurrent | CNS Tumor | Medulloblastoma Recurrent | CNS Cancer | Medulloblastoma, Non-WNT/Non-SHH | Brain Tumor, Pediatric | CNS Neoplasm | Brain Tumor, Refractory | Medulloblastoma, Non-WNT/Non-SHH, Group 3 | Medulloblastoma, Non-WNT/Non-SHH, Group 4

United States
Odense University Hospital
Manchester Metropolitan University; University of Southern Denmark; Curtin University

Completed

COgNitive FuncTional Therapy+ for Chronic Low Back paIn (CONFeTTI)

Chronic Low-back Pain

Denmark
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Active, not recruiting

Bariatric Surgery Versus Diet Alone in the Bile Acid Pathway and Weight Loss

Obesity

United States
National Cancer Center, Japan
Pfizer; Korean Cancer Study Group

Active, not recruiting

PAlbociclib Plus Tamoxifen for the Treatment of Hormone Receptor-positive, HER2-negative Advanced Breast Cancer Women - Asian studY (PATHWAY)

Breast Neoplasms

Korea, Republic of, Singapore, Japan, Taiwan
Novartis Pharmaceuticals

Active, not recruiting

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Dosimetry of [177Lu]Lu-PSMA-617 in Chinese Adult Male Patients With Progressive PSMA-Positive mCRPC

Metastatic Castration-Resistant Prostate Cancer (mCRPC)

China
Memorial Sloan Kettering Cancer Center
Weill Medical College of Cornell University; Broad Institute

Completed

Clinical and Molecular Correlates of Positron Emission Tomography (PET) With 89Zr-DFO-huJ591 in Metastatic Prostate Cancer

Prostate Cancer

United States
Novartis Pharmaceuticals

Completed

Study of Oral cMET Inhibitor INC280 in Patients With EGFR Wild-type (wt), Advanced Non-small Cell Lung Cancer (NSCLC) (Geometry Mono-1)

Carcinoma, Non-Small-Cell Lung

Italy, Spain, Germany, Japan, Taiwan, Belgium, Netherlands, Singapore, Argentina, France, Israel, Sweden, Korea, Republic of, Lebanon, United Kingdom, United States, Austria, Mexico, Norway, Russian Federation
Andrew Meltzer
BioMérieux

Completed

Urgent Care Management of Respiratory Illness Enabled With Novel Testing Pathway (URGENT)

Acute Respiratory Infection | Viral Infection | Upper Resp Tract Infection

United States
Dana-Farber Cancer Institute

Enrolling by invitation

Pathways to Advance Targeted and Helpful Serious Illness Conversations (PATH-SIC) ((PATH-SIC))

Breast Cancer | Gynecologic Cancer | Thoracic Cancer | Gastrointestinal Cancer | Genitourinary Cancer

United States
City of Hope Medical Center

Active, not recruiting

Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor

Unspecified Childhood Solid Tumor, Protocol Specific | Solid Tumor | Ewing Sarcoma | Unspecified Adult Solid Tumor, Protocol Specific | Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Recurrent Neuroblastoma | Recurrent Adult Soft Tissue Sarcoma | Recurrent Adult Brain Tumor | Recurrent... and other conditions

United States
Navire Pharma Inc., a BridgeBio company

Active, not recruiting

First-in-Human Study of the SHP2 Inhibitor BBP-398 in Patients With Advanced Solid Tumors

Tumor, Solid

United States
University of Washington
National Institute of Allergy and Infectious Diseases (NIAID); National Institute... and other collaborators

Completed

Pharmacy Delivery to Expand the Reach of PrEP in Kenya

HIV Prevention

Kenya
New Mexico Cancer Care Alliance
National Institute of General Medical Sciences (NIGMS)

Active, not recruiting

Enhancing Cancer Prevention and Control Pathways-Native Health Initiative

Cancer, Breast | Cancer, Colon | Cancer, Cervix

United States
SpringWorks Therapeutics, Inc.

Available

Individual Patient Compassionate Use of Mirdametinib

Neurofibromatosis Type 1-Associated Plexiform Neurofibromas | Histiocytic Neoplasm | Other MAP-K Pathway Driven Diseases
Hospices Civils de Lyon

Completed

Elderly Patient at Risk of Loss of Mobility, Exercise - Primary Care, Prevention, Care Pathways (PRISME-3P)

Elderly Patient (>70 Years) | Loss of Mobility

France
Anna Martling
Skane University Hospital; Uppsala University Hospital

Active, not recruiting

Adjuvant Low Dose Aspirin in Colorectal Cancer (ALASCCA)

Colorectal Cancer

Sweden, Denmark, Norway, Finland
Kent State University
The Cleveland Clinic

Completed

Transcranial Magnetic Stimulation in Smokers: an Examination of Mediating Neural Pathways.

Smoking

United States
Yale University
National Institute on Aging (NIA)

Completed

Pathway to Detection & Differentiation of Delirium & Dementia in the Emergency Department (IMPACT)

Delirium | Cognitive Impairment | Dementia | Emergency Care

United States
OnKure, Inc.

Active, not recruiting

NAUTILUS: OKI-179 Plus Binimetinib in Patients With Advanced Solid Tumors in the RAS Pathway (Phase 1b) and NRAS-mutated Melanoma (Phase 2)

Melanoma | NRAS Gene Mutation | RAS Mutation

United States
Rennes University Hospital

Active, not recruiting

Evaluation of the Impact of Lesions of the Motor and Proprioceptive Brain and Pan-medullary Pathways on Their Clinically and Electrophysiologically Assessed Function in Multiple Sclerosis (MS-TRACTS)

Multiple Sclerosis, Relapsing-Remitting

France
Centre for Addiction and Mental Health
York University

Terminated

A Remote Electronically Delivered Integrated Care Pathway: A Feasibility Study (eCARIBOU)

Major Depressive Disorder

Canada
National Cancer Institute (NCI)

Active, not recruiting

Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell Cancers

Uterine Cervical Neoplasms | Small Cell Lung Carcinoma | Ovarian Neoplasms | Carcinoma, Neuroendocrine | Extrapulmonary Small Cell Cancer | Carcinoma, Non-Small -Cell Lung

United States
National Cancer Institute (NCI)

Completed

Liposomal Doxorubicin in Treating Children With Refractory Solid Tumors

Bone Cancer | Brain Tumor | Kidney Tumor | Childhood Soft Tissue Sarcoma | Childhood Liver Cancer

United States
Centre Hospitalier Universitaire de Nīmes

Completed

Multidisciplinary Care Pathway With Electronic Patient Reported Outcomes (ePRO) Post-operative Follow-up of Breast Cancer Surgery Complications to Optimize Patient Quality of Life (BEAUTIFY-3)

Breast Cancer

France
Azienda Ospedaliero, Universitaria Pisana

Completed

Maternal and Fetal Metabolic Changes (MoMM-FET)

Pregnancy Related | Maternal-Fetal Relations | Metabolism Disorder, Glucose

Italy
University of North Carolina, Chapel Hill
National Institutes of Health (NIH); National Institute on Aging (NIA)

Completed

Physical Activity Pathway for Patients With Osteoarthritis in Primary Care (OA-PCP) (R33) (OA-PCP)

Osteoarthritis

United States
Oslo University Hospital
The Dam Foundation

Active, not recruiting

The Caregiver Pathway - An Intervention to Support Caregivers of Critically Ill Patients

Caregiver Stress Syndrome

Norway
Elsan
Cemka-Eval

Withdrawn

Medical and Medico-economic Evaluation Comparing the Follow-up of Patients Undergoing Bariatric Surgery (SPOC)

Bariatric Surgery Candidate

France
University of Miami
National Eye Institute (NEI)

Completed

BCI and Evaluation of Visual and Task Performance in Subjects With Eye Diseases

Glaucoma | Macular Degeneration | Retinal Degeneration | Optic Neuropathy | Glaucoma Suspect | Visual Pathway Disorder

United States
Carnegie Mellon University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Understanding Shared Psychobiological Pathways

Breast Neoplasms
European Organisation for Research and Treatment...

Terminated

Dissecting the Pathways of Therapy Resistance in Early Breast Cancer (MINDACTRelapse)

Breast Cancer

Belgium, Netherlands
Northwell Health

Completed

Using a Transcutaneous Electrical Auricular Stimulator to Harness the Cholinergic Anti-Inflammatory Pathway (TEACAP)

Healthy Volunteers

United States
Genentech, Inc.

Completed

My Pathway: A Study Evaluating Herceptin/Perjeta, Tarceva, Zelboraf/Cotellic, Erivedge, Alecensa, and Tecentriq Treatment Targeted Against Certain Molecular Alterations in Participants With Advanced Solid Tumors

Neoplasms | Bladder Cancer | Solid Tumors | Biliary Cancer | Salivary Cancer

United States
AstraZeneca

Completed

Study to Understand Clinical Characteristics, Treatment Pathway in Chronic Lymphocytic Leukemia (CREEK)

Chronic Lymphocytic Leukemia

Malaysia, Saudi Arabia, India, Mexico, Brazil, Singapore, Egypt, Taiwan, Argentina, Chile, Colombia, Costa Rica, Dominican Republic, Kuwait, Panama, Turkey, United Arab Emirates
Institut Curie

Active, not recruiting

The Integrated Support and Palliative in Cancer Day-care Hospital for Patients With Advanced Cancers: Impact on Quality of Life, Care Pathways and Support for Caregivers (HDJ-SPI)

Cancer, Advanced

France
Johns Hopkins University
National Institute of Mental Health (NIMH); PAIDEK/Promotion de la Famille... and other collaborators

Active, not recruiting

Pathways to Improved Adolescent Mental Health in Conflict Affected Families

Mental Health Issue | Gender Equality

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Characterization of Apolipoprotein A-I Pathways in Idiopathic Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis

United States
Haukeland University Hospital
Helse Stavanger HF; Helse Fonna; Helse Forde; Haraldsplass Deaconess Hospital

Completed

Penicillin Allergy Delabeling Project (PenProv)

Penicillin Allergy

Norway
European Pathway Association
KU Leuven; University of Eastern Piedmont

Completed

European Quality of Care Pathways Study on Proximal Femur Fracture (EQCP-PFF) (EQCP-PFF)

Femoral Fractures
National Cancer Institute (NCI)

Completed

Phase II Trial of the Gamma-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors/Aggressive Fibromatosis

Desmoid Tumors | Aggressive Fibromatosis

United States
Yale University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Investigating the Role of the Polyol Pathway in the Central Nervous System Production of Fructose

Hyperglycaemia (Diabetic)

United States
JS InnoPharm, LLC

Suspended

JSI-1187-01 Monotherapy and in Combination With Dabrafenib for Advanced Solid Tumors With MAPK Pathway Mutations

Solid Tumors

United States
Jules Bordet Institute

Completed

Inferior Epigastric Lymp Node (IELN) Basin as a Possible Systemic Metastatic Pathway of Ovarian Peritoneal Metastases (OvEpiLyPath)

Carcinomatosis, Peritoneal

Belgium
Ascendis Pharma Bone Diseases A/S

Active, not recruiting

A Trial Investigating the Safety, Tolerability and Efficacy of TransCon PTH Administered Daily in Adults With Hypoparathyroidism (PaTHway)

Endocrine System Diseases | Parathyroid Diseases | Hypoparathyroidism

United States, Canada, Norway, Denmark, Germany, Hungary, Italy

Search clinical trials for: Wnt pathway

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