Search clinical trials for: complement system

Total 249090 results

University of Massachusetts, Worcester
National Cancer Institute (NCI)

Completed

Take a Break (TAB): mHealth-assisted Skills Building Challenge for Unmotivated Smokers

Smoking Cessation

United States
Jaseng Medical Foundation

Completed

Long Term Follow-up of Cervical Myelopathy Inpatients Treated With Integrated Complementary and Alternative Medicine

Cervical Myelopathy

Korea, Republic of
University Hospital Freiburg

Withdrawn

Aripiprazole Augmentation Therapy in Treatment-resistant Depression

Therapy-resistant Depression

Germany
University Hospital Freiburg

Withdrawn

Olanzapine Augmentation Therapy in Treatment-resistant Depression: a Double-blind Placebo-controlled Trial

Therapy-resistant Depression

Germany
Andres J. M. Ferreri

Completed

Intralesional Rituximab for the Treatment of Conjunctival Indolent Lymphoma (IRIS)

Ocular Adnexal Mucosa-Associated Lymphoid Tissue Lymphoma

Italy
Sebastian Videla

Completed

Investigating the Efficacy and Safety ICATIBANT For The Treatment of Patients With SARS-CoV-2 (COVID-19) Infection (ICAT·COVID)

COVID-19 Pneumonia

Spain
Wake Forest University Health Sciences
National Center for Complementary and Integrative Health (NCCIH)

Completed

Improvisational Movement for People With Memory Loss and Their Caregivers (IMOVE)

Dementia | Mild Cognitive Impairment | Alzheimer's Disease (Incl Subtypes)

United States
Vanderbilt University Medical Center

Withdrawn

Here's the Buzz: Evaluating Pediatric Post Op Pain and Nausea Following Tonsillectomy Surgery

Tonsillectomy

United States
Hospital Israelita Albert Einstein

Terminated

e-Nature VR: Evaluation of the Impact of Virtual Reality During Breast Biopsy (e-Nature VR)

Pain | Breast Pain

Brazil
InflaRx GmbH
Iqvia Pty Ltd

Terminated

Safety and Efficacy Study of IFX-1 in add-on to Standard of Care in GPA and MPA

Granulomatosis With Polyangiitis (GPA) | Microscopic Polyangiitis (MPA)

United States, Canada
Shire

Completed

A Study of Lanadelumab to Prevent Hereditary Angioedema (HAE) Attacks in Children (SPRING)

Hereditary Angioedema

United States, Canada, Germany, Hungary, Spain
Alexion Pharmaceuticals

Terminated

Efficacy and Safety Study of IV Ravulizumab in Patients With COVID-19 Severe Pneumonia

Pneumonia, Viral | Acute Respiratory Distress Syndrome | Acute Lung Injury | COVID-19 Severe Pneumonia

United States, Spain, United Kingdom, France, Japan
University of Massachusetts, Worcester
The Miriam Hospital; National Center for Complementary and Integrative Health...

Completed

Asthma Symptom Management Through Mindfulness Training

Asthma

United States
University of the Basque Country (UPV/EHU)

Completed

Effects of Complementary Therapies in People With Mild to Moderate Parkinson's Disease

Parkinson Disease

Spain
Massachusetts General Hospital
National Center for Complementary and Integrative Health (NCCIH)

Completed

The BRIgHT Program: Building Resilience in HIV Together

Resilience, Psychological

United States
Icahn School of Medicine at Mount Sinai
National Center for Complementary and Integrative Health (NCCIH)

Completed

Effects of Mindfulness Training on Chronic Inflammation in HIV-Infected Adults

HIV

United States
Baylor College of Medicine

Completed

Complementary Combination Therapy for Cocaine Dependence

Cocaine Dependence

United States
CENTOGENE GmbH Rostock

Completed

Epidemiological Analysis for Hereditary Angioedema Disease (EHA)

Abdominal Pain | Functional Abdominal Pain

United Kingdom, Germany, Turkey, Poland, Italy, Japan
Bioverativ, a Sanofi company
Assign Data Management and Biostatistics GmbH; Quest Diagnostics-Nichols Insitute and other collaborators

Completed

Safety, Tolerability and Activity of BIVV009 in Healthy Volunteers and Patients With Complement Mediated Disorders (BIVV009-01)

End-stage Renal Disease (ESRD) | Cold Agglutinin Disease (CAD) | Bullous Pemphigoid (BP) | Warm Autoimmune Hemolytic Anemia (WAIHA)

Austria
International Centre for Diarrhoeal Disease Research...
University of California, Berkeley; Emory University; University of California... and other collaborators

Active, not recruiting

WASH Benefits Bangladesh

Diarrhea | Malnutrition | Child Development

Bangladesh
Catalyst Biosciences

Terminated

A Natural History Study to Assess the Clinical Outcomes of Patients With Complement Factor I Deficiency-Mediated Disease

Recurrent Bacterial Infection, Autoimmune Disorder

United States
Yale University
National Alliance for Research on Schizophrenia and Depression

Completed

Effects of Salvinorin A in Healthy Controls

Healthy

United States
Takeda

Completed

A Study of Icatibant (TAK-667) in Japanese Children and Teenagers With Acute Attacks of Hereditary Angioedema

Hereditary Angioedema

Japan
CENTOGENE GmbH Rostock

Completed

Biomarker for Hereditary AngioEdema Disease (BioHAE)

Hereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | C1 Esterase Inhibitor Deficiency | HAE | Angio Edema | C4 Deficiency | Hereditary Angioedema Type III

Turkey, Armenia, Georgia, India, Peru, Poland, Romania
University of Sao Paulo General Hospital

Completed

Meditation as Complementary Treatment for Chronic Hypertension in Pregnancy

Hypertension | Hypertension, Pregnancy-Induced | Hypertension in Pregnancy

Brazil
Karen Derefinko, PhD
National Center for Complementary and Integrative Health (NCCIH)

Completed

SMART Trial: Community Stigma Reduction

Opioid-use Disorder | Stigma, Social

United States
University of Maryland, Baltimore
Chinese University of Hong Kong; National Center for Complementary and Integrative...

Completed

Dose Escalation Trial of Traditional Chinese Medicine for Irritable Bowel Syndrome (TCM- IBS) (TCM-IBS)

Irritable Bowel Syndrome

Hong Kong
CENTOGENE GmbH Rostock

Terminated

Hereditary Angioedema Kininogen Assay (HAEKA)

Hereditary Angioedema

Germany
University of Massachusetts, Worcester
National Center for Complementary and Integrative Health (NCCIH); BrightOutcome...

Completed

Group intEgrative MINdfulness Over the Internet Using an Online Platform (GEMINI)

Pain, Chronic

United States
Technological Centre of Nutrition and Health, Spain
University Rovira i Virgili; Hospital Universitari Sant Joan de Reus; Fundació... and other collaborators

Completed

Study of the Bioavailability of a Food Supplement Rich in Melatonin Administered Sublingually and Orally (MELATONIN) (MELATONIN)

Biological Availability

Spain
KalVista Pharmaceuticals, Ltd.

Completed

A Single and Multiple Doses Safety, Tolerability, Pharmacokinetics and Food Effect Study of KVD824 in Healthy Volunteers

Hereditary Angioedema

United Kingdom
The First Affiliated Hospital of Soochow University

Completed

A Safety and Efficacy Study of NAC in Patients With TA-TMA

Hematologic Diseases | Thrombotic Microangiopathies

China
Organon and Co

Completed

SINGULAIR (R) as Complementary Therapy to Fixed Association Regimen (0476-363) (STAR)

Asthma
University of Washington
Mayo Clinic; National Institute of Arthritis and Musculoskeletal and Skin Diseases... and other collaborators

Completed

Trial of Inserting Prevalence Information Into Lumbar Spine Imaging Reports (LIRE)

Back Pain | Low Back Pain | Lumbar Pain | Backache

United States
Grace McComsey
National Center for Complementary and Integrative Health (NCCIH)

Completed

Zinc Supplementation and Cardiovascular Risk in HIV

Inflammation | HIV

United States
Jaseng Medical Foundation

Completed

Long Term Follow-Up of Post Neck Pain Patients Accompanying Ossification of Posterior Longitudinal Ligament Treated With Integrated Complementary and Alternative Medicine: Observational Study

Medicine, Korean Traditional | OPLL

Korea, Republic of
AO GENERIUM

Withdrawn

Efficacy and Safety of GNR-038 vs Berinert® in Patients With Hereditary Angioedema

Hereditary Angioedema

Russian Federation
Hoffmann-La Roche

Completed

A Study to Provide Complementary Efficacy, Safety and Patient Reported Outcomes Data in Participants With Active Relapsing Forms of Multiple Sclerosis (MS) in a Pragmatic Setting (PRO-MSACTIVE)

Multiple Sclerosis

France
University of North Carolina, Chapel Hill
National Center for Complementary and Integrative Health (NCCIH); University... and other collaborators

Completed

FARE Peanut SLIT and Early Tolerance Induction (FARE/SLIT)

Food Hypersensitivity | Peanut Hypersensitivity | Peanut Allergy | Food Allergy

United States
NHS National Waiting Times Centre Board
British Heart Foundation; University of Glasgow; NHS Greater Clyde and Glasgow; Chief Scientist Office of the Scottish Government

Active, not recruiting

Coronary Microvascular Function and CT Coronary Angiography (CorCTCA) (CorCTCA)

Angina, Stable | Angina Pectoris, Variant | Microvascular Angina

United Kingdom
Ohio State University

Completed

Reiki Intervention for Seriously Ill Elders Intensive Care Unit (RISE-ICU) (RISE-ICU)

Mechanical Ventilation Complication | Complementary Health Approach

United States
Immunogenics, LLC
National Institutes of Health (NIH); National Center for Complementary and...

Completed

Latiglutenase as a Treatment for Celiac Disease

Celiac Disease

United States
Lund University

Withdrawn

Physical Activity as a Complementary Treatment in POTS (POTS)

POTS

Sweden
KalVista Pharmaceuticals, Ltd.

Completed

Phase 1 Crossover Study in Healthy Subjects to Evaluate the PK Profile of KVD824 Following Single and Multiple Doses of Modified Release (MR) Formulations

Hereditary Angioedema

United Kingdom
University Hospital, Basel, Switzerland
Pharming Technologies B.V.

Terminated

Conestat Alfa in the Prevention of Severe SARS-CoV-2 Infection in Hospitalized Patients With COVID-19

Coronavirus Infections

Switzerland, Brazil, Mexico
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

A Proof-of-Mechanism Study to Determine the Effect of Danicopan on C3 Levels in Participants With C3G or IC-MPGN

C3 Glomerulopathy | C3 Glomerulonephritis | Dense Deposit Disease | Immune Complex Mediated Membranoproliferative Glomerulonephritis | Membranoproliferative Glomerulonephritis Types I, II, and III

Netherlands, Australia, Belgium
Kjeld Andersen
University of New Mexico; Addiction Research Unit, Technische Universität,... and other collaborators

Completed

Treatment of Alcohol Problems in the Elderly

Alcohol Use Disorders

Denmark
Ensysce Biosciences
National Institute on Drug Abuse (NIDA)

Completed

Oral Nafamostat in Healthy Volunteers

Pharmacokinetics

United States
Clinica Luganese Moncucco

Completed

Elderly Demented Patients: Aromatherapy Complementary to Psychopharmacotherapy Psychological Disorders and BPSD Behavior

BPSD (Behavioral and Psycological Symptoms of Dementia)

Switzerland
Francis Corazza

Completed

Evaluation of Interleukine 6 (and Other Cytokines and Inflammatory Markers) in COVID-19 Patients With a Systemic Inflammatory Response Syndrome

COVID-19

Belgium

Search clinical trials for: complement system

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