Search clinical trials for: dose adjustments

Total 20979 results

Instituto Bernabeu

Not yet recruiting

TRAP Study: Testosterone for Androgen Receptor Polymorphism (TRAP)

Fertility Disorders

Spain
Bayer
Merck Sharp & Dohme LLC

Recruiting

A Study to Learn How Safe Starting Vericiguat at a Dose of 5 Milligrams is in Participants With Chronic Heart Failure With Reduced Ejection Fraction

Chronic Heart Failure With Reduced Ejection Fraction

Spain, United States, Argentina, Italy, Hungary, Poland, Sweden
National Cancer Centre, Singapore

Recruiting

Impacts of Durian Consumption on Human Microbiome and Metabolome in Healthy Staff Volunteers (DURIOME)

Diet, Food and Nutrition

Singapore
Second Affiliated Hospital of Soochow University
Shanghai Regenelead Therapies Co., Ltd.

Recruiting

A Study on the Safety and Tolerability of RGL-193 in Patients With Advanced Parkinson's Disease

Advanced Parkinson's Disease

China
Agyany Pharma LTD

Recruiting

High-Dose Ambroxol in GBA1-Related Parkinson

Parkinson Disease | GBA Gene Mutation

Israel
Hunazine Biotech S.L.

Recruiting

Assessment of a Novel Fixed-dose Combination (FDC) Drug VR-AD-1005 for the Treatment of Acute Watery Diarrhea in Cholera

Cholera

Bangladesh
Northern Ontario School of Medicine

Recruiting

Evaluation of a Direct Oral Penicillin Challenge in a Rural Community (DOC)

Allergy Penicillin

Canada
Stichting European Myeloma Network
Janssen Pharmaceutica

Recruiting

Phase 2 Study Applying MRD Techniques for Participants With Previously Untreated Multiple Myeloma Treated With D-VRd Prior To and After High-dose Therapy Followed by ASCT - TAURUS (TAURUS)

Multiple Myeloma

Austria, Greece, Italy, Netherlands, Germany
Morten Hostrup, PhD

Not yet recruiting

Testosterone-induced Muscle Memory and Underlying Mechanisms

Skeletal Muscle Physiology
National Research Center for Hematology, Russia

Recruiting

Multicenter Study of Safety and Efficacy Nivolumab at the Fixed Dose 40 mg (Nivo40) in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed PMBL

Primary Mediastinal Lymphoma

Russian Federation
AstraZeneca

Recruiting

A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced or Metastatic Solid Tumors (CYCAD-1)

ER+ HER2- Advanced Breast Cancer | High-grade Serous Ovarian Cancer (HGSOC)

United States, United Kingdom, Korea, Republic of, Australia, Spain
Kyowa Kirin Korea Co., Ltd.

Recruiting

Post Marketing Surveillance Study to Observe Safety and Effectiveness of NEPHOXIL ® in S. Korea Patients

Hyperphosphatemia

Korea, Republic of
Saint Vincent's Hospital, Korea

Recruiting

Clinical Comparison of Low-dose Rosuvastatin Plus Ezetimibe Combination Therapy and High-dose Rosuvastatin Monotherapy in Patients With Minimal to Intermediate Coronary Artery Disease Without Percutaneous Coronary Intervention (ALMIGHTY)

Coronary Artery Disease | Dyslipidemias | Primary Prevention

Korea, Republic of
Biocad

Recruiting

A Trial of the Safety and Efficacy of Single-Dose Administration of ANB-010 in Subjects With Hemophilia A (EDELWEISS)

Hemophilia A

Russian Federation
Benitec Biopharma, Inc.

Recruiting

A Study to Evaluate the Safety and Clinical Activity of Intramuscular Doses of BB-301 Administered to Subjects With Oculopharyngeal Muscular Dystrophy With Dysphagia

Oculopharyngeal Muscular Dystrophy

United States
San Diego State University

Recruiting

Elucidating the Minimal Effective Dose of Prunes for Bone Health in Postmenopausal Women

Bone Disease, Metabolic

United States
Spago Nanomedical AB

Recruiting

A Dose Escalation and Expansion Study of [177Lu]Lu-SN201 in Participants With Advanced Cancer (Tumorad)

Solid Tumor | Metastatic Cancer | Refractory Cancer | Locally Advanced Solid Tumor | Unresectable Solid Tumor | Recurrent Solid Tumor

Australia
National Cancer Institute (NCI)

Not yet recruiting

Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial

Breast Carcinoma | Breast Ductal Carcinoma In Situ | Breast Lobular Carcinoma In Situ | Estrogen Receptor-Positive Breast Carcinoma

United States
Institute of Medical Biology, Chinese Academy of...
Sichuan Center for Disease Control and Prevention

Recruiting

Phase I Clinical Trial of Diphtheria-Tetanus-acellular Pertussis Component Combined Vaccine

Pertussis | Tetanus | Diphtheria

China
The First Affiliated Hospital of Xinxiang Medical...

Not yet recruiting

Adebrelimab Combined With Bevacizumab and Docetaxel for Advanced Non-Squamous Non-small Cell Lung Cancer After Progression on First-line Immunotherapy

Non-small Cell Lung Cancer
University Hospital, Strasbourg, France

Recruiting

Interest of High-dose Gentamicin Cement Associated With Clindamycin in Changes of Hip and Knee Prostheses (HKP)

Hip or Knee Replacement

France
Sang-Won Um

Not yet recruiting

A Prospective Study for the Early Diagnosis of Lung Cancer in Korean Females

Health Risk Behaviors
Beijing Tiantan Hospital

Not yet recruiting

Safety and Preliminary Efficacy of Aleeto in Amyotrophic Lateral Sclerosis (SPECIALS)

Amyotrophic Lateral Sclerosis

China
ProDa BioTech, LLC
University of Alabama at Birmingham; Georgia State University

Recruiting

ProAgio in Pancreatic Ductal Adenocarcinoma (PDAC)

Pancreatic Ductal Carcinoma

United States
AstraZeneca

Recruiting

Study of AZD9829 in CD123+ Hematological Malignancies

Hematological Malignancies

United States, Spain, Korea, Republic of, Italy, China, Japan, Taiwan, Australia, Germany
Augusta University
Georgia Rehabilitation Institute

Recruiting

Chronic Remote Ischemic Conditioning in Vascular Cognitive Impairment: A Dose Escalation Study

Cognition Disorder | Age-related Cerebral White Matter Changes

United States
Centre Hospitalier Universitaire de Saint Etienne
Takeda France

Not yet recruiting

Comparison of Vedolizumab Treatment to Adalimumab Dose Intensification in Crohn's Disease Patients With Loss of Response or Biomarker Activity to Adalimumab on First Line With Therapeutic Drug Concentration. (VEDIAN)

Crohn's Disease

France
Sunnybrook Health Sciences Centre

Recruiting

De-escalated Dose SBRT in Localized Prostate Cancer (DESTINATION-MRL)

Prostate Cancer

Canada
Pamela Munster
National Cancer Institute (NCI)

Recruiting

Olaparib and ASTX727 in BRCA1/2- and Homologous Recombination Deficient (HRD)-Mutated Tumors

BRCA1 Mutation | BRCA2 Mutation | PALB2 Gene Mutation | ATM Gene Mutation | BRCA Mutation | Checkpoint Kinase 2 Gene Mutation

United States
Kyoto Drug Discovery and Development Co., Ltd.

Recruiting

A Study of the Efficacy and Safety of KUS121 in Participants With Acute Non-Arthritic Central Retinal Artery Occlusion (CRAO) (GION)

Central Retinal Artery Occlusion

United States
Pfizer

Recruiting

A Study to Understand the Effect of Multiple Ascending Doses of PF-07293893 in Healthy Adult Participants

Healthy Participants

Belgium, United States
Peking University People's Hospital
Peking University First Hospital; Beijing Friendship Hospital; Chinese PLA General... and other collaborators

Recruiting

Teriflunomide Plus High-dose Dexamethasone as First-line Treatment in Newly Diagnosed Primary Immune Thrombocytopenia

Immune Thrombocytopenia

China
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

A Randomized, Double-Blind, Dose-Escalation, Placebo-Controlled Phase I Clinical Trial Investigating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Oral Doses of HRS-7085 Tablets in Healthy Subjects, With Assessment of Food Effects

Inflammatory Bowel Disease
Daiichi Sankyo
AstraZeneca

Recruiting

A Study to Provide Continued Access to and Assess Long-Term Safety of the Study Drug(s)

Metastatic Cancer | Advanced Cancer

Spain, Korea, Republic of, Belgium, Italy, France, United States, Australia, Japan, Taiwan, United Kingdom
Clinical Nutrition Research Center, Illinois Institute...

Recruiting

Understanding Dose Related Effects of Strawberry (STRW)

Inflammation | Insulin Resistance | Insulin Sensitivity | Pre-diabetes

United States
University Hospital, Strasbourg, France

Recruiting

Monitoring of Fluoroscopy Time on the Dose Delivered to the Patient During Vertebral Cementoplasty Procedures (CIMVER)

Vertebra Compression Fracture

France
Jeanette Du

Not yet recruiting

Low Dose Atropine for Symptomatic Vitreous Floaters

Vitreous Floaters

United States
Ferring Pharmaceuticals

Recruiting

A Randomised Trial Comparing the Ovarian Response of a Starting Dose of Either 10 μg or 15 μg Follitropin Delta (FE 999049) to a Starting Dose of Either 150 IU or 225 IU Follitropin Alfa (GONAL-F) in Conventional Regimens in China (COCO)

Infertility, Female

China
Ifakara Health Institute
University of Oxford

Not yet recruiting

In-vivo Transmission Model in Semi-immune Adults

Controlled Human Malaria Infection | Malaria Transmission | Induced Blood Stage Malaria Infection | Malaria Challenge

Tanzania
AstraZeneca
AstraZeneca K.K.

Recruiting

A Study to Assess the Efficacy, Safety and Tolerability of Different Doses of AZD0780 in Patients With Dyslipidemia (PURSUIT)

Dyslipidemia

Denmark, Hungary, Spain, United States, Japan, Czechia, Slovakia, Canada
National Cancer Institute (NCI)

Recruiting

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Neuroblastoma | Ganglioneuroblastoma, Nodular

United States
King's College Hospital NHS Trust

Recruiting

Low-dose Tolvaptan for Inpatient Hyponatraemia.

Hyponatremia | SIADH

United Kingdom
Celgene

Recruiting

A Study to Assess the Effects of Itraconazole, Food, and pH on the Drug Levels of BMS-986368 in Healthy Participants

Healthy Participants

United States
Zhihong LU

Not yet recruiting

Dose of Remimazolam in Children for Intubation (DRIP)

Anesthesia
University of Chicago

Not yet recruiting

Using MRI to Identify Areas to Receive Lower Doses of Radiation Treatment in Men With Prostate Cancerdose Mapping to Preserve Quality of Life

Prostate Cancer

United States
Enanta Pharmaceuticals, Inc
hVIVO Services Limited

Recruiting

A Controlled Phase 2a Study to Evaluate the Efficacy of EDP-323 Against Respiratory Syncytial Virus Infection in a Virus Challenge Model

RSV Infection

United Kingdom
Tomsk National Research Medical Center of the Russian...

Recruiting

High-dose Inhalations of Nitric Oxide in the Treatment of Pneumonia

Nosocomial Pneumonia | Community-acquired Pneumonia

Russian Federation
GlaxoSmithKline
Medicines for Malaria Venture

Recruiting

A Study to Investigate the Safety of GSK4024484 in Healthy Adult Participants

Malaria, Falciparum

United Kingdom
University of Illinois at Chicago

Recruiting

Abemaciclib Dose Escalation to Maintain Intensity (ADE-MI) (BRE-09)

Breast Cancer

United States
Guangzhou Patronus Biotech Co., Ltd.
Yantai Patronus Biotech Co., Ltd.

Not yet recruiting

Safety and Immunogenicity of Recombinant COVID-19 Trivalent Protein Vaccine （CHO Cell）LYB002V14 in Booster Vaccination

SARS-CoV-2 | COVID-19 Vaccine

China

Search clinical trials for: dose adjustments

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