Search clinical trials for: exposure and response prevention

Total 476448 results

University of Oslo
Oslo Metropolitan University; Mills DA

Completed

Fat Quality on Blood Lipids and Immune Response (NoMa)

Dietary Prevention

Norway
University of Ottawa

Completed

Physiological Responses in Young and Older Adults During a Prolonged Simulated Heatwave (HW1)

Aging | Physiological Stress | Heat Stress

Canada
Emory University
Centers for Disease Control and Prevention

Completed

Body Compartment Pharmacokinetics of Anti-retroviral Agents That May be Considered for Future On-demand Peri-exposure HIV Prophylaxis Regimens

HIV/AIDS

United States
National Institute of Allergy and Infectious Diseases...

Completed

Dose, Safety, Tolerability, and Immunogenicity of an HIV-1 Vaccine, VRC-HIVRGP096-00-VP, With Alum in Healthy Adults

Human Immunodeficiency Virus (HIV) | Human Immunodeficiency Virus Prevention

United States
Centers for Disease Control and Prevention
Ministry of Health, Brazil; Evandro Chagas National Institute of Infectious...

Completed

Efficacy of 3 Regimens of Chloroquine and Primaquine for Treatment of P. Vivax Malaria, Cruzeiro do Sul, Acre, Brazil

Malaria, Vivax | P Vivax

Brazil
University of Missouri-Columbia
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Sex Differences in Reflex Responses to Intermittent Hypoxia

Healthy Participants

United States
Ontario Clinical Oncology Group (OCOG)
Aboca Spa Societa' Agricola

Completed

Investigation of the Anti-Cancer Activity of Artichoke Extract in an Asbestos-Exposed Population (ABOCA1)

Asbestos Exposure

Canada
Novartis Pharmaceuticals

Completed

β-RELIEVED - REsponse in Acute fLare and In prEVEntion of episoDes of Re-flare in Gout - Extension 3 (E3) (β-RELIEVED)

Acute Gouty Arthritis Flares

United States, Estonia, Lithuania, Germany, Russian Federation, Canada, Australia, Latvia, Ukraine
University of California, Los Angeles
University of California, San Diego; California HIV/AIDS Research Program; Los... and other collaborators

Completed

Pre-exposure Prophylaxis (PrEP) Adherence Enhancement Guided by iTAB and Drug Levels for Women (AEGiS)

HIV Prevention

United States
Guy's and St Thomas' NHS Foundation Trust
Merck Sharp & Dohme LLC

Completed

Study of the Golimumab Exposure-Response Relationship Using Serum Trough Levels (GO-LEVEL)

Ulcerative Colitis

United Kingdom
University of Southern Denmark
Odense University Hospital; Aarhus University Hospital; University of Copenhagen and other collaborators

Completed

Chronic Inflammatory Disease, Lifestyle and Treatment Response (BELIEVE)

Autoimmune Diseases | Inflammatory Bowel Diseases | Uveitis | Psoriasis | Spondylarthropathies | Crohn Disease (CD) | Arthritis, Rheumatoid (RA) | Arthritis, Psoriatic (PsA) | Hidradenitis Suppurativa (HS) | Colitis, Ulcerative (UC)

Denmark
Microbicide Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy...

Completed

EMBRACE (Evaluation of Maternal and Baby Outcome Registry After Chemoprophylactic Exposure) (EMBRACE)

Pregnancy Related

United States, South Africa, Uganda, Zimbabwe
Alyatec

Completed

Evaluation of the Nasal and Conjunctival Response in Subjects Allergic to Birch Pollen in the ALYATEC Environmental Exposure Chamber

Allergic Rhinitis | Rhinoconjunctivitis | Allergy to Pollen

France
University of North Carolina, Chapel Hill
Environmental Protection Agency (EPA)

Completed

Human Biological Responses to Low Level Ozone (SNOZ)

Environmental Exposure | Nasal Inflammation

United States
University of California, San Francisco
San Francisco AIDS Foundation; California HIV/AIDS Research Program

Completed

Study of Truvada for HIV Pre Exposure Prophylaxis Using Daily Directly Observed Therapy to Look at Potential Interactions Between Truvada and Hormone Therapy (I-BrEATHe)

HIV Prevention | Transgender Health

United States
National Jewish Health

Completed

Exposure in Epigenetic Regulation of Immune Response in Chronic Beryllium Disease (CBD) (BeEpiGen)

Chronic Beryllium Disease

United States
University of Aarhus
Lund University; University of Copenhagen; Danish Technological Institute; ASP-HOLMBLAD... and other collaborators

Completed

CANDLE - A Study of Acute Health Effects of Exposure to Particles Generated by Candles

Inflammatory Response | Symptoms and Signs

Denmark
Public Health Foundation Enterprises, Inc.
University of California, San Francisco; California HIV/AIDS Research Program; San Francisco Department of Public Health and other collaborators

Completed

The Stay Study: A Demonstration Project Advancing PrEP Delivery in the San Francisco Bay Area Transgender Community

Transgender Persons | Pre-Exposure Prophylaxis

United States
Public Health Foundation Enterprises, Inc.
National Institute of Mental Health (NIMH); Emory University; San Francisco Department... and other collaborators

Completed

DOT Diary Mobile App for Pre-Exposure Prophylaxis Adherence in Young Men

Risk Behavior | HIV Prevention | Adherence, Medication | Pre-Exposure Prophylaxis

United States
Public Health Foundation Enterprises, Inc.
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Completed

HOME Study: a Combination Support Package to Increase Uptake of PrEP and HIV/STI Testing

Sexually Transmitted Diseases | HIV Prevention | Pre-Exposure Prophylaxis

United States
Julio Ramirez
University of Louisville

Terminated

Patients Response to Early Switch To Oral:Osteomyelitis Study (PRESTO:Osteo)

Osteomyelitis

United States
Rutgers University

Completed

The Effect of Brown Adipose Tissue Activation on Insulin Sensitivity in Humans

Obesity | Insulin Sensitivity

United States
Instituto de Investigación Sanitaria Aragón

Completed

Lifestyle Modification Program in the Prevention and Treatment of Depression

Depression

Spain
Centers for Disease Control and Prevention
Ministry of Health, Thailand; Bangkok Metropolitan Administration Medical College...

Completed

Bangkok Tenofovir Study, an HIV Pre-exposure Prophylaxis Trial, Bangkok, Thailand

HIV Infections

Thailand
Duke Kunshan University
National Natural Science Foundation of China; Fudan University; Taizhou Municipal...

Completed

Reducing Second-hand Smoke Exposure Among Young Children in Rural China

Second Hand Tobacco Smoke

China
Henry Ford Health System

Withdrawn

Negative Pressure Wound Therapy for Surgical Site Infection Prevention in Common Femoral Artery Exposure

Surgical Site Infection | Groin Infections

United States
Istanbul University - Cerrahpasa (IUC)

Unknown

The Effect of BIS-guided Propofol Induction on Hemodynamic Response in Patients With Cardiac Risk.

Anesthesia, General
Medstar Health Research Institute
Merck Sharp & Dohme LLC

Completed

Does the HPV Vaccine Cause the Same Response in Adolescent Kidney and Liver Transplant Patients as in Healthy Controls?

Cervical Cancer | Warts | Hpv

United States
National Institute of Allergy and Infectious Diseases...

Terminated

Phase I Study to Evaluate a Human Monoclonal Antibody (MAb) 10E8VLS Administered Alone or Concurrently With MAb VRC07-523LS Via Subcutaneous Injection in Healthy Adults

Healthy Adult Immune Response

United States
Affiliated Cancer Hospital & Institute of Guangzhou...

Unknown

Comparison of Anesthesia Effects of Sevoflurane and Propofol Combined With Dexmedetomidine in Intraoperative Neuromonitoring During Thyroidectomy

Thyroid Nodule

China
Dr. Ruth K.M. Pfau Civil Hospital, Karachi

Unknown

Hemodynamic Stability of Dexmedetomidine in Hypertensive Patients Undergoing Laparoscopic Cholecystectomy

Hypertension | Laparoscopic Cholecystectomy

Pakistan
Cidara Therapeutics Inc.

Completed

CD101 Compared to Caspofungin Followed by Oral Step Down in Subjects With Candidemia and/or Invasive Candidiasis-Bridging Extension (STRIVE)

Mycoses | Candidemia | Fungemia | Fungal Infection | Invasive Candidiasis

United States, Spain, Belgium, Russian Federation, Greece, Bulgaria, Canada, Hungary, Italy, Romania
Philip Morris Products S.A.

Completed

A 26-week Extension of the ZRHR-ERS-09-US Study Evaluating Biological and Functional Changes in Healthy Smokers After Switching to THS 2.2

Smoking

United States
National Cancer Institute (NCI)
Boston University; Duke University; University of Southern California; University... and other collaborators

Completed

Study of Lung Health Among Workers Exposed to Diesel Exhaust

Inflammation Biomarkers | mRNA Expression | nitroPAH Adducts

China
University of Minnesota
National Cancer Institute (NCI)

Completed

Effects of Prior Exposure to Conflicting Health Information on Responses to Subsequent Unrelated Health Messages

Communication Research

United States
National Institute of Allergy and Infectious Diseases...

Completed

VRC 605: Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRC-HIVMAB075-00-AB (VRC07-523LS), Administered Intravenously or Subcutaneously to Healthy Adults

HIV Prevention

United States
Regional Center for Disease Control and Prevention...
Farhat Hached Hospital, Tunisia; Fattouma Bourguiba, Tunisia

Unknown

Chemoprevention Clinical Trial of COVID-19: Hydroxychloroquine Post Exposure Prophylaxis (APCC-19)

SARS-CoV Infection
University Hospital, Basel, Switzerland

Completed

Pain Response to Cannabidiol in Opioid-induced Hyperalgesia, Acute Nociceptive Pain and Allodynia By Using a Model Mimicking Acute Pain in Healthy Adults (CANAB II)

Hyperalgesia | Allodynia | Opioid-induced Hyperalgesia | Acute Nociceptive Pain

Switzerland
Albert Einstein College of Medicine

Completed

Association Between Body Size and Response to Hydromorphone in ED

Pain

United States
Teva Pharmaceuticals USA

Withdrawn

An Open-Label, Single-Center Study to Evaluate the Exposure-Response Relationship Between the Plasma Drug Concentrations and the Change From Baseline in QTc at Steady State Following Once-daily Administration of CASSIPA® in Opioid Dependent Subjects.

Evaluation of QTc Interval
UCB Biopharma S.P.R.L.

Completed

A Study to Evaluate the Antibody Response of Influenza Vaccination Following Concomitant Exposure to Bimekizumab in Healthy Subjects

Healthy Volunteers

United States
Centre of Postgraduate Medical Education

Unknown

Different Regimens in Influenza Postexposure Chemoprophylaxis in Children

Influenza | Prevention | Exposure

Poland
Kirby Institute
Government of Western Australia, Department of Health; Western Australia AIDS...

Completed

Western Australian Pre-exposure Prophylaxis for HIV Implementation Trial (PrEPIT-WA)

HIV Prevention

Australia
Laureate Institute for Brain Research, Inc.

Completed

Cerebellar Neuromodulation to Enhance Fear Extinction and Predict Response to Exposure Therapy

Anxiety Disorders | Social Phobia

United States
Emory University
Centers for Disease Control and Prevention

Completed

Body Compartment Pharmacokinetics of Anti- Retroviral Agents That May be Used for Future HIV Post- Exposure Prophylaxis. (PEP2)

HIV Infections

United States
Khon Kaen University

Completed

Comparison of Dexmedetomidine and Fentanyl to Prevent Hemodynamic Response to Skull Pins Application

Hemodynamic Response | Skull Pins Application

Thailand
Hamad Medical Corporation

Unknown

Post Exposure Prophylaxis in Healthcare Workers Exposed to COVID-19 Patients (HCQ-COVID19)

COVID 19
Postgraduate Institute of Medical Education and...

Completed

Efficacy of Hydroxychloroquine (HCQ) as Post Exposure Prophylaxis (PEP) for Prevention of COVID-19 (PEP-CQ)

CoVID-19

India
Pluristem Ltd.

Unknown

Open-label Phase I Study for PEP or Treatment of HS-ARS PLX-R18 for the Post-Exposure Prevention (PEP) or Treatment of Hematopoietic Syndrome of Acute Radiation Syndrome (HS-ARS) (HS-ARS)

Ionizing Radiation Exposure
Mansoura University

Unknown

Efficacy of Negative Pressure Wound Closure Therapy by PICO System in Prevention of Complications of Femoral Artery Exposure

Wound Infection | Wound Surgical

Egypt

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