Search clinical trials for: human study

Total 135110 results

Gilead Sciences

Recruiting

Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Patients With Hormone Receptor-positive/Human Epidermal Growth Factor Receptor 2 Negative (HR+/HER2-) Metastatic Breast Cancer Who Have Received Endocrine Therapy (ASCENT-07)

Stage IV Breast Cancer | Locally Advanced or Unresectable Metastatic Breast Cancer

Taiwan, Korea, Republic of, Australia, Greece, Spain, United States, United Kingdom, France, Israel, Malaysia, Japan, Belgium, Poland, China, Germany, Czechia, Singapore, Hungary, Brazil, Italy, South Africa, Portugal, Argentina, Hong... and more
Incyte Corporation

Recruiting

A Study to Evaluate the Safety of INCA33890 in Participants With Advanced or Metastatic Solid Tumors

Advanced Solid Tumors | Solid Tumors | Metastatic Solid Tumors

United States, Spain, United Kingdom, France, Italy, Denmark, Switzerland
Xuanzhu Biopharmaceutical Co., Ltd.

Not yet recruiting

A Study of the Absorption, Metabolism and Excretion of [14C]XZP-3621 in Human

Healthy Volunteers

China
Hoffmann-La Roche

Recruiting

A First-in-Human Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7507062 in Participants With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United Kingdom, Spain, Germany, Poland, South Africa, Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...
Princess Beatrix Muscle Foundation

Recruiting

Add-on Intravenous Immunoglobulins in Early Myositis (TIMEISMUSCLE)

Myositis | Dermatomyositis | Polymyositis | Antisynthetase Syndrome | Immune-Mediated Necrotizing Myopathy | Inflammatory Myopathy, Idiopathic

Netherlands
Shanghai Zhimeng Biopharma, Inc.

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CB06-036 in Subjects With Chronic Hepatitis B

Chronic Hepatitis b
Onward Therapeutics

Recruiting

First-in-human Study of OT-A201 in Patients With Selected Hematological Malignancies and Solid Tumors

Solid Tumor | Hematological Malignancy

France
Axoltis Pharma
Centre for Human Drug Research, Netherlands

Recruiting

MAD Study of NX210c (CHDR2235)

Healthy Elderly

Netherlands
Ascendis Pharma Endocrinology Division A/S

Recruiting

A US Non-interventional, Effectiveness and Safety Study of Patients Treated With SKYTROFA (SkybriGHt)

Growth Hormone Deficiency

United States
University of Wisconsin, Madison
National Institute of Dental and Craniofacial Research (NIDCR)

Recruiting

Study Transplanting Bone Marrow Cells Into Salivary Glands to Treat Dry Mouth Caused by Radiation Therapy

Head and Neck Cancer | Xerostomia

United States
Baylor College of Medicine
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

The Goodnight Screen Media Study

Sleep | Sleep Hygiene

United States
Boehringer Ingelheim

Recruiting

Lunsayil 1: A Study to Test Whether Spesolimab Helps People With a Skin Disease Called Hidradenitis Suppurativa

Hidradenitis Suppurativa

United States, Korea, Republic of, Israel, Spain, Australia, Japan, Italy, Germany, Denmark, Belgium, Lithuania, China, Canada, Malaysia, Singapore, New Zealand, France, Mexico, Netherlands, Greece, United Kingdom, Bulgaria, Philipp... and more
Memorial Sloan Kettering Cancer Center

Recruiting

A Study Using Human Papillomavirus (HPV) DNA Testing to Detect HPV-Related Oropharyngeal Cancer (OPC)

Oropharyngeal Cancer | HPV-Related Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma

United States
Weizmann Institute of Science

Recruiting

Human Phenotype Project Study Protocol

Adult Disease

Israel
Affimed GmbH

Recruiting

First-in-Human Dose Escalation Study of AFM28 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia

Spain, France, Denmark
Galapagos NV

Recruiting

Prospective Observational Study of Effectiveness and Safety of Filgotinib in Participants With Ulcerative Colitis (UC) (GALOCEAN)

Ulcerative Colitis

Belgium, Netherlands, France, Italy, Germany, Norway, United Kingdom, Ireland, Austria
Fondazione Italiana Linfomi - ETS

Recruiting

Multilayer Biological Characterization of Advanced Follicular Lymphoma: a Translational Study From FIL_FOLL12 Trial (FIL_FOLL-BIO)

Follicular Lymphoma

Italy
Vesteck, Inc.
Prince of Wales Hospital, Sydney

Recruiting

Suture-Tight™ First-in-Human Safety and Performance Study (Suture-Tight™)

Aortic Aneurysm, Abdominal

Australia
Fujian Shengdi Pharmaceutical Co., Ltd.

Recruiting

Clinical Study to Evaluate the Safety, Tolerance and Pharmacokinetic Characteristics of Single Administration of HRS-5635 Injection in Chinese Healthy Subjects and the Safety, Tolerance, Pharmacokinetics and Antiviral Effect of Multiple Administration in Patients With Chronic Hepatitis B

Chronic Hepatitis B

China
ImmuneMed, Inc.

Recruiting

A Study to Assess the Efficacy and Safety of Burfiralimab(hzVSF-v13) and OAD (Oral Antiviral Drug)

Chronic Hepatitis B

Korea, Republic of
Lee's Pharmaceutical Limited

Not yet recruiting

Non-inferiority Study of ZK-A03 in Treatment of Herpes Zoster Before and After the Alteration of the Active Ingredient Manufacturer

Herpes Zoster
Eli Lilly and Company

Recruiting

A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular Risk (ACHIEVE-4)

Cardiovascular Diseases | Obesity | Overweight | Type 2 Diabetes | Chronic Kidney Disease | Overweight or Obesity

United States, Italy, Spain, Korea, Republic of, India, Turkey, Austria, Puerto Rico, Romania, Brazil, Czechia, Germany, Mexico, Argentina, Greece, Slovakia
University Hospital of Limerick

Recruiting

The Biomechanical Study of Diseased Human Carotid, Femoral and Abdominal Aortic Tissue

Vascular Diseases

Ireland
Bayer

Recruiting

A Study to Compare Darolutamide Given With Androgen Deprivation Therapy (ADT) With ADT in Men With Hormone Sensitive Prostate Cancer and Raise of Prostate Specific Antigen (PSA) Levels After Local Therapies (ARASTEP)

Biochemically Recurrent Prostate Cancer

Austria, Spain, France, United States, Australia, Brazil, Germany, Taiwan, Denmark, China, Netherlands, Japan, Canada, Finland, Italy, Hungary, Portugal, United Kingdom, Poland, Israel, New Zealand, Sweden, Belgium, Czechia
West German Study Group
Agendia

Recruiting

PROOFS-Registry - Premenopausal Women With Breast Cancer Optimally Treated With OFS (PROOFS)

Female Breast Cancer

Germany
USDA, Western Human Nutrition Research Center

Recruiting

Postprandial Monocyte Study (PPMS)

Inflammation | Nutrition | Immune System

United States
Fang Wang

Recruiting

A Study on Antiviral Treatment of Chronic Hepatitis B in Children

Chronic HBV Infection

China
Beijing Ditan Hospital

Recruiting

Study of COVID-19 Infection and Its Clinical Prognosis in Chronic Hepatitis B Patients With Antiviral Therapy

Chronic Hepatitis B | COVID-19 Infection

China
Overseas Pharmaceuticals, Ltd.
Beijing Capton Pharmaceutical Technology Development Co., LTD

Not yet recruiting

An Open Label, Balanced, Randomized, Two-Treatment, Two-Period, Two-Sequence, Two-way Crossover, Oralcomparative Pharmacokinetic（PK）Study of Lacosamide Extended-Release Tablets , Adult, Human Subjects Under Fasting Conditions.

Epilepsy

China
Philogen S.p.A.

Recruiting

A Study to Evaluate the Safety and Dosimetry of 68Ga-labelled OncoFAP Derivatives in Solid Tumors (FAPrimo)

Breast Cancer | Colorectal Cancer | Pancreas Adenocarcinoma | Oesophageal Cancer

Italy
Landos Biopharma Inc.

Recruiting

Study to Evaluate the Clinical Activity and Safety of Oral NX-13 in Moderate to Severe Ulcerative Colitis

Ulcerative Colitis

United States, Belgium, Italy, Poland
Nordsjaellands Hospital
University of Copenhagen

Recruiting

Reduction of Metabolic Acidosis in Patients With Chronic Kidney Disease in Stage 4 and 5 (REMA-CKD)

Kidney Diseases | Renal Insufficiency | CKD | Metabolic Acidosis | Pre-dialysis

Denmark
Jnana Therapeutics

Recruiting

First-in-Human, Multiple Part Clinical Study of JNT-517 in Healthy Participants and in Participants With Phenylketonuria

Phenylketonuria

United States, Australia
Annexon, Inc.

Recruiting

A Study of ANX009 in Adult Participants With Lupus Nephritis

Lupus Nephritis

Philippines, Taiwan
Ascendis Pharma Endocrinology Division A/S

Recruiting

A Post-Authorisation Safety Study (PASS) of Patients Treated With Lonapegsomatropin (SkyPASS)

Growth Hormone Deficiency

United States
Celldex Therapeutics

Recruiting

A Study of CDX-0159 in Patients With Eosinophilic Esophagitis (EvolvE)

Eosinophilic Esophagitis

United States, Spain, Australia, United Kingdom, Canada, Italy, Poland, Germany
University of North Carolina, Charlotte
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

The SKyRoCKeT Study (SKyRoCKeT)

Healthy

United States
Boston Medical Center
National Institute on Drug Abuse (NIDA); Victory Programs Mobile Prevention...

Not yet recruiting

PrEP and MOUD Rapid Access for Persons Who Inject Drugs: The CHORUS+ Study (CHORUS+)

Opioid Use Disorder

United States
IRCCS SYNLAB SDN

Recruiting

Study of Brain Anatomo-functional Substrates Related to the Use of Human Tool by Means of Simultaneous Acquisition of Magnetic Resonance Imaging and Electroencephalogram

Patients With Frontal and Parietal Lobe Dysfunction

Italy
Scorpion Therapeutics, Inc.

Recruiting

First-in-Human Study of STX-478 as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

Breast Cancer | Gynecologic Cancer | HNSCC | Solid Tumors, Adult

United States, Spain, France, Italy
Eli Lilly and Company

Recruiting

A Study of Mirikizumab (LY3074828) in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT-URGE)

Ulcerative Colitis | Ulcerative Colitis Chronic

United States, United Kingdom, Poland, Czechia, Italy, Hungary, France, Germany, Slovakia, Belgium
Northeast Normal University

Recruiting

A Study of the Telerehabiliation Intervention Effect of the Tai Chi Exercise on Elderly With Sarcopenia

Sarcopenia

China
Gilead Sciences

Recruiting

Study of Bulevirtide in Participants Who Have Normal or Impaired Liver Function

Chronic Hepatitis D Infection

United States
Chantel Burkitt
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Chronic Postsurgical Pain (CPSP)

Cerebral Palsy | Chronic Post Surgical Pain

United States
Hoffmann-La Roche

Recruiting

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7565020 in Healthy Participants and in Participants With Chronic Hepatitis B Virus Infection

Chronic Hepatitis B

Korea, Republic of, United States, Thailand, Hong Kong, Spain, New Zealand, Bulgaria, Taiwan, France
Children's Oncology Group

Recruiting

A Study of SNDX-5613 in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia

Recurrent Acute Lymphoblastic Leukemia | Refractory Acute Lymphoblastic Leukemia | Recurrent Mixed Phenotype Acute Leukemia | Refractory Mixed Phenotype Acute Leukemia | Refractory Acute Leukemia of Ambiguous Lineage | Recurrent Acute Leukemia of Ambiguous Lineage | Recurrent Acute Myeloid Leukemia... and other conditions

United States
First Affiliated Hospital of Guangxi Medical University
Genmedicn Biopharma Ltd.

Recruiting

A Study Evaluating the Safety and Efficacy of LentiRed Drug Product in Transfusion-dependent β-Thalassemia [TDT]

Transfusion Dependent Beta-Thalassemia

China
Ipsen

Recruiting

A Study to Observe Demography and the Outcome of Prostate Cancer Patients Treated With 6-month Triptorelin Formulation in Italy (REAL6T)

Prostate Cancer

Italy
Gilead Sciences

Recruiting

A Multiple-Dose Study of Bulevirtide in Participants With Normal and Impaired Renal Function

Chronic Hepatitis D Infection

United States
First Affiliated Hospital of Guangxi Medical University
Genmedicn Biopharma Ltd.

Recruiting

A Study Evaluating the Safety and Efficacy of the GMCN-508A Drug Product in Transfusion-dependent α-Thalassemia Participants

Transfusion-dependent α-Thalassemia

China

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