Search clinical trials for: oropharyngeal colonization

Total 1259 results

Sanford Health

Active, not recruiting

EValuating the Safety Of De-escaLated Head and Neck Irradiation in HPV positivE Oropharynx Cancer in Non-smokers/Minimal Smokers

Oropharyngeal Cancer

United States
Dana-Farber Cancer Institute
Stand Up To Cancer

Completed

Trial To Test Safety And Efficacy Of Vaccination For Incurable HPV 16-Related Oropharyngeal, Cervical And Anal Cancer

Cancer of Head and Neck | Cancer of Cervix | Cancer of Anus

United States
VA Office of Research and Development
Edward Hines Jr. VA Hospital

Completed

Clinical Impact of Respiratory-Swallow Training on Refractory Dysphagia in Oropharyngeal Head and Neck Cancer

Head and Neck Cancer | Dysphagia

United States
VU University of Amsterdam
Wageningen University and Research; Maag Lever Darm Stichting; Cidrani; WholeFiber and other collaborators

Active, not recruiting

Gut Health Enhancement by Eating Favourable Food (GEEFomjebuik)

Microbial Colonization

Netherlands
Hacettepe University

Completed

The Turkish Oropharyngeal Dysphagia Screening Test for Patients and Professionals

Swallowing Disorder

Turkey
Tufts Medical Center

Terminated

Probiotic Lactobacillus GG to Eliminate VRE Colonization (VRE)

Vancomycin Resistant Enterococcal Colonization

United States
Canadian Cancer Trials Group
AstraZeneca

Active, not recruiting

Cisplatin + Radiotherapy vs Durvalumab + Radiotherapy Followed by Durvalumab vs Durvalumab + Radiotherapy Followed by Tremelimumab + Durvalumab in Intermediate-Risk HPV-Positive Oropharyngeal SCC

Oropharyngeal Squamous Cell Carcinoma

Canada, Spain, Belgium, Italy
Tata Medical Center

Completed

Dose Escalation Versus Standard in Laryngopharyngeal Cancers (INTELHOPE)

Malignant Neoplasm of Oropharynx Stage III | Malignant Neoplasm of Larynx Stage III | Malignant Neoplasm of Hypopharynx Stage III | Malignant Neoplasm of Oropharynx Stage IVa | Malignant Neoplasm of Oropharynx Stage IVb | Malignant Neoplasm of Larynx Stage IV | Malignant Neoplasm of Hypopharynx... and other conditions

India
University of Alabama at Birmingham

Active, not recruiting

Oxalobacter Formigenes Colonization and Urinary Oxalate Excretion

Calcium Oxalate Urolithiasis

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Active, not recruiting

HPV-16/18 E6/E7-Specific T Lymphocytes, Relapsed HPV-Associated Cancers, HESTIA (HESTIA)

Human Papillomavirus-Related Carcinoma | Human Papillomavirus Positive Oropharyngeal Carcinoma | Human Papillomavirus Positive Cervical Carcinoma | Human Papillomavirus Positive Anal Carcinoma | Human Papillomavirus Positive Vulvar Carcinoma | Human Papillomavirus Positive Penile Carcinoma

United States
Abramson Cancer Center at Penn Medicine

Active, not recruiting

TORS De-Intensification Protocol Version 2.0: Dose and Volume Reduction in the Neck

Oropharyngeal Cancer | Human Papilloma Virus | Squamous Cell Carcinoma

United States
Endeavor Biomedicines, Inc.

Active, not recruiting

A Study Evaluating the Safety and Efficacy of ENV-101 (Taladegib) in Patients With Advanced Solid Tumors Harboring PTCH1 Loss of Function Mutations

Solid Tumors With PTCH1 Loss-of-function Mutations

United States
Shanghai Ninth People's Hospital Affiliated to...

Completed

Early Enteral Nutritional Supplementation on Patients With Oral and Oropharyngeal Cancer Undergoing Radio(Chemo)Therapy After Surgical

Malnutrition

China
Leiden University Medical Center
Spaarne Gasthuis

Completed

Studying Respiratory Infections and Colonisation in Children Using Daily Minimally-invasive Nasal Sampling (SAMSAM)

Respiratory Tract; Infection, Upper (Acute) | Colonization, Asymptomatic

Netherlands
St. Jude Children's Research Hospital

Completed

A Pilot Study of Influenza Viruses Isolated From Immunocompromised Children and Adolescents

Influenza, Human

United States
Robert L. Ferris, MD, PhD
Bristol-Myers Squibb

Active, not recruiting

Adjuvant De-Escalated Radiation + Adjuvant Nivolumab for Intermediate-High Risk P16+ Oropharynx Cancer

Oropharynx Squamous Cell Carcinoma | Carcinoma, Squamous Cell of Head and Neck

United States
Thomas Jefferson University

Completed

Exercise Training and Behavioral Modification for the Improvement of Physical Activity in Head and Neck Cancer Patients Undergoing Cancer Treatment

Head and Neck Carcinoma | Lung Carcinoma | Oral Cavity Carcinoma | Paranasal Sinus Carcinoma | Stage III Laryngeal Cancer AJCC v8 | Stage IV Laryngeal Cancer AJCC v8 | Hypopharyngeal Carcinoma | Laryngeal Carcinoma | Stage IVA Laryngeal Cancer AJCC v8 | Stage IVB Laryngeal Cancer AJCC v8 | Stage IVC Laryngeal... and other conditions

United States
Jennifer Choe
Arcus Biosciences, Inc.

Withdrawn

A Study of Concurrent Chemoradiation in Combination With or Without PD1 Inhibitor AB122 Adenosine 2a Receptor / Adenosine 2b Receptor Inhibitor AB928 Therapies in Locally Advanced Head and Neck Cancers (PANTHEoN)

Head and Neck Cancer | Squamous Cell Carcinoma of Head and Neck | Oropharynx Cancer | Oral Cavity Cancer | Oropharynx Squamous Cell Carcinoma | Pharynx Cancer | Larynx Cancer | Hypopharynx Cancer | Oral Cavity Squamous Cell Carcinoma | Hypopharynx Squamous Cell Carcinoma

United States
National Cancer Institute (NCI)

Active, not recruiting

HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers

Cervical Cancer | Anal Cancer | Oropharyngeal Cancer | Vulvar, Vaginal, Penile, Rectal Cancer | HPV Positive Cancer

United States
Turnstone Biologics, Corp.
Takeda

Terminated

Study of TBio-6517 Given Alone or in Combination With Pembrolizumab in Solid Tumors (RAPTOR)

Renal Cell Carcinoma | Cervical Cancer | Solid Tumor | Mesothelioma | Melanoma (Skin) | Oropharynx Cancer | HPV Positive Oropharyngeal Squamous Cell Carcinoma | Microsatellite Stable Colorectal Cancer | Cutaneous Squamous Cell Carcinoma

United States, Canada, Korea, Republic of
Rochester General Hospital

Active, not recruiting

Evaluate Pathogens and Immunity to Acute Otitis Media in Healthy Children. (AOM)

Nasopharyngeal Colonization and Acute Otitis Media

United States
IRCCS Policlinico S. Donato

Withdrawn

Central Venous Catheter Insertion Site and Colonization in Pediatric Cardiac Surgery (PRECiSE)

Congenital Heart Disease | Heart; Surgery, Heart, Functional Disturbance as Result | Central Venous Catheter Associated Bloodstream Infection | Newborn; Infection | Central Line-associated Bloodstream Infection (CLABSI)

Italy
Jonsson Comprehensive Cancer Center
AstraZeneca

Terminated

Stereotactic Body Radiation Therapy and Durvalumab With or Without Tremelimumab Before Surgery in Treating Participants With Human Papillomavirus Positive Oropharyngeal Squamous Cell Caner

Oropharyngeal Squamous Cell Carcinoma | Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Pathologic... and other conditions

United States
BLIS Technologies Limited

Active, not recruiting

Colonization of Skin by M. Luteus Q24 Probiotic

Microbial Colonization

New Zealand
National Cancer Institute (NCI)

Active, not recruiting

Combination Immunotherapy in Subjects With Advanced HPV Associated Malignancies

Cervical Cancer | Anal Cancer | Oropharyngeal Cancer | HPV Cancers | Vulvar, Vaginal, Penile, Rectal Cancer

United States
Emory University
Cepheid

Terminated

FMT for MDRO Colonization After Infection in Renal Transplant Recipients (PREMIX)

Infection Due to Resistant Organism

United States
University of Bern
University of Alabama at Birmingham; University of Southern California; Louisiana... and other collaborators

Active, not recruiting

Genital Tract Infections, the Vaginal Microbiome and Gestational Age at Birth Among Pregnant Women in South Africa

HIV Infections | Premature Birth | Microbial Colonization | Pregnancy; Infection | Bacterial Vaginosis | Trichomonas Vaginitis | Neisseria Gonorrheae Infection | Chlamydia Trachomatis Infection | Mycoplasma Genitalium Infection | Genital Mycoplasma Infection | Vaginal Candida | Sexually Transmitted Infections... and other conditions

South Africa
University of Florida

Active, not recruiting

Frequent Standardized Oral Care to Improve Health Outcomes in Premature Infants in the Neonatal Intensive Care Unit

Microbial Colonization | Ventilator Associated Pneumonia

United States
Nebraska Methodist Health System

Active, not recruiting

De-Escalation Protocol Of HPV Mediated Oropharyngeal Squamous Cell Carcinoma

Oropharynx Cancer | HPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Clinical Stage

United States
Northern State Medical University

Completed

The Effect of Supraglottic and Oropharyngeal Decontamination on the Incidence of Ventilator-associated Pneumonia (SGDC-VAP)

Brain Injuries | Encephalitis | Seizures | Trauma Injury | Meningitis | Pancreatitis | Acute Respiratory Distress Syndrome | Abdominal Sepsis

Russian Federation
The Netherlands Cancer Institute
AstraZeneca

Active, not recruiting

Olaparib and Radiotherapy in Head and Neck Cancer

Head and Neck Neoplasms | Carcinoma, Squamous Cell | Laryngeal Cancer Stage II | Laryngeal Cancer Stage III

Netherlands
Rutgers, The State University of New Jersey
National Cancer Institute (NCI)

Active, not recruiting

Swallowing Outcomes and Circulating Tumor DNA in Patients With HPV Related Oropharyngeal Cancer Treated With Transoral Surgery and Reduced Intensity Adjuvant Therapy

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Oropharyngeal Human Papillomavirus-Positive Squamous...

United States
Linkoeping University

Completed

Impact of Postoperative Skin Disinfection With Chlorhexidine on Bacterial Colonization

Surgical Site Infection

Sweden
University of Novi Sad
Merck Sharp & Dohme LLC

Completed

Pneumococcal Nasopharyngeal and Oropharyngeal Carriage in Adults

Preference, Patient

Serbia
Shanghai General Hospital, Shanghai Jiao Tong University...

Completed

Study of Microbiota in Bile From Patients With Common Bile Duct Stone During ERCP

Microbial Colonization | Common Bile Duct Calculi | Cholangiopancreatography, Endoscopic Retrograde

China
University of Michigan Rogel Cancer Center
National Cancer Institute (NCI); VA Ann Arbor Healthcare System

Active, not recruiting

Individualized Adaptive De-escalated Radiotherapy for HPV-related Oropharynx Cancer

Oropharynx Cancer

United States
Maastricht Radiation Oncology
Brigham and Women's Hospital; Princess Margaret Hospital, Canada

Active, not recruiting

Predicting Radiological Extranodal Extension in Oropharyngeal Carcinoma Patients Using AI (AI4rENE)

Head and Neck Carcinoma

Canada, Netherlands, United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Erlotinib Hydrochloride in Treating Patients With Metastatic or Recurrent Squamous Cell Carcinoma of the Head and Neck

Metastatic Squamous Cell Carcinoma of the Hypopharynx | Metastatic Squamous Cell Carcinoma of the Larynx | Metastatic Squamous Cell Carcinoma of the Oral Cavity | Metastatic Squamous Cell Carcinoma of the Oropharynx | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous... and other conditions

United States
Washington University School of Medicine

Active, not recruiting

Surgery Followed by Risk-Directed Post-Operative Adjuvant Therapy for HPV-Related Oropharynx Squamous Cell Carcinoma: "The Minimalist Trial (MINT)" (MINT)

HPV Related Oropharyngeal Squamous Cell Carcinoma

United States
Walter Reed National Military Medical Center
US Army Medical Research Institute of Infectious Diseases

Active, not recruiting

The Female Microbiome in Patients Undergoing Bladder Instillation Therapy

Microbial Colonization | Interstitial Cystitis | Bladder Pain Syndrome

United States
University of Alberta

Completed

Staying Connected: a Mobile Health Study With the Noona® and Mobili-T® Systems

Oropharynx Cancer

Canada
Lawson Health Research Institute

Active, not recruiting

Primary Radiotherapy Versus Primary Surgery for HPV-Associated Oropharyngeal Cancer (ORATOR2)

Oropharyngeal Cancer

Canada, Australia
Hvidovre University Hospital
Chr Hansen

Completed

Probiotic Efficacy in VRE Eradication (PROVE)

VRE Colonization

Denmark
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Active, not recruiting

Radiation Therapy With Cisplatin or Cetuximab in Treating Patients With Oropharyngeal Cancer

Head and Neck Cancer | Precancerous Condition

United States, Canada
Hospital General de México Dr. Eduardo Liceaga

Completed

Non-caloric Sweeteners Levels in Breast Milk and Newborn's Blood and Effect on Microbiota's Composition.

Microbial Colonization

Mexico
Mayo Clinic
National Cancer Institute (NCI)

Completed

Radiation Therapy and Docetaxel in Treating Patients With HPV-Related Oropharyngeal Cancer

Human Papillomavirus Infection | Stage IVA Oropharyngeal Squamous Cell Carcinoma | Stage IVB Oropharyngeal Squamous Cell Carcinoma | Stage I Oropharyngeal Squamous Cell Carcinoma | Stage II Oropharyngeal Squamous Cell Carcinoma | Stage III Oropharyngeal Squamous Cell Carcinoma

United States
University of Chicago
National Cancer Institute (NCI)

Active, not recruiting

Nab-paclitaxel and Carboplatin Followed by Response-Based Local Therapy in Treating Patients With Stage III or IV HPV-Related Oropharyngeal Cancer (OPTIMA)

Human Papilloma Virus Infection | Stage III Squamous Cell Carcinoma of the Oropharynx | Stage IVA Squamous Cell Carcinoma of the Oropharynx | Stage IVB Squamous Cell Carcinoma of the Oropharynx

United States
M.D. Anderson Cancer Center
Sanofi

Withdrawn

Phase 2 Study of Neoadjuvant SAR444245 Plus Cemiplimab in HPV Related Oropharynx Squamous Cell Carcinoma

Head and Neck Cancer | Oropharynx Cancer | Squamous Cell Carcinoma

United States
University Medical Center Groningen

Completed

Timing of Maternal Antibiotic Prophylaxis During a Cesarean Section and the Early Infant Gut Microbiome (CSBabyBiome)

Microbial Colonization | Cesarean Section Complications | Antibiotic Side Effect

Netherlands
University of British Columbia
Dublin City University

Active, not recruiting

Oral Probiotic Supplementation in Pregnancy to Reduce Group B Streptococcus Colonization (OPSiP)

Group B Streptococcus Carrier in Childbirth

Canada

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