Search clinical trials for: third-line therapy

Total 51955 results

Gilead Sciences

Completed

A Study on the Safety and Effectiveness of Adefovir Dipivoxil in Combination With Anti-HIV Therapy (HAART) in HIV-Positive Patients

HIV Infections

United States, United Kingdom, Germany, Canada, France
Agouron Pharmaceuticals

Terminated

Safety and Effectiveness of 3 Anti-HIV Treatments in Patients Who Have Failed Previous Treatments Containing Nelfinavir

HIV Infections

United States
Glaxo Wellcome

Completed

Safety and Effectiveness of Giving Two Nucleoside Reverse Transcriptase Inhibitors Alone or in Combination With 141W94 to HIV-Infected Children Who Have Never Received Protease Inhibitors

HIV Infections

United States
Eunice Kennedy Shriver National Institute of Child...

Unknown

Constraint-Based Therapy to Improve Motor Function in Children With Cerebral Palsy

Cerebral Palsy | Motor Deficits

United States
Merck Sharp & Dohme LLC

Completed

The Effectiveness of Indinavir Plus Zidovudine Plus Lamivudine in HIV-Infected Patients With No Symptoms of Infection

HIV Infections

United States, Canada
Ortho Pharmaceuticals

Completed

A Double-Blind, Placebo-Controlled Study With Open-Label Follow-Up To Determine the Safety and Efficacy of r-HuEPO in AIDS Patients With Anemia Induced by Their Disease and AZT Therapy

HIV Infections | Cytopenias

United States
Pfizer

Completed

An Open-Label Study of the Use of Azithromycin in Patients With Symptomatic Disseminated Mycobacterium Avium-Intracellulare Complex (MAC) Infection Failing Current Therapy

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Pfizer

Completed

A Randomized Study of Daily and Intermittent Prophylactic Regimens for the Prevention of Disseminated Mycobacterium Avium Complex (MAC) and Fungal Infections in HIV-Infected Patients

HIV Infections | Mycoses | Mycobacterium Avium-Intracellulare Infection

United States
Pharmacia and Upjohn

Completed

A Double-Blind, Randomized, Dose Response Study of Three Doses of Delavirdine Mesylate (U-90152S) in Combination With Zidovudine (ZDV) Versus ZDV Alone in HIV-1 Infected Individuals With CD4 Counts of 200-500mm3

HIV Infections

United States, Puerto Rico
Anderson Clinical Research
Hoechst Marion Roussel

Completed

Tolerance, Safety, and Activity of Rifapentine Alone and in Combination Therapy in AIDS Patients With Mycobacterium Avium Complex Bacteremia.

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
National Center for Research Resources (NCRR)
University of North Carolina

Completed

Phase I/II Study of Monoclonal Factor IX Concentrate for Factor IX Deficiency

Hemophilia B | Factor IX Deficiency
Glaxo Wellcome

Completed

A Study to Compare the Safety and Effectiveness of Two Dosing Schedules of Lamivudine in Combination With Two Other Anti-HIV Drugs

HIV Infections

United States
Merck Sharp & Dohme LLC

Completed

Safety and Effectiveness of an Anti-HIV Drug Combination in HIV-Positive Patients Who Have Failed Previous Treatment With Protease Inhibitors

HIV Infections

United States
PPD

Unknown

Differences Between Women and Men Taking a Combination of Indinavir, Ritonavir, Enteric-Coated Didanosine, and Stavudine Who Previously Took Anti-HIV Drugs

HIV Infections

United States, Puerto Rico
Gilead Sciences

Completed

The Safety and Effectiveness of Cidofovir in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States, United Kingdom
Glaxo Wellcome

Unknown

Comparison of GW433908 and Nelfinavir in HIV Patients Who Have Not Had Antiretroviral Therapy

HIV Infections

United States
U.S. Bioscience

Completed

A Compassionate Treatment Protocol for the Use of Trimetrexate Glucuronate (Neutrexin) With Leucovorin Protection for European Adult Patients (>= 13 Years Old) With Pneumocystis Carinii Pneumonia

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
National Institute on Alcohol Abuse and Alcoholism...

Completed

Drug Therapy for Alcohol Detoxification

Alcoholism

United States
Triangle Pharmaceuticals

Completed

A Randomized, Double-Blind Study of MKC-442 Combined With Viracept in Patients Who Are Epivir + Retrovir Experienced and Are Protease Inhibitor- and Non-Nucleoside Reverse Transcriptase Inhibitor-Naive

HIV Infections

United States
Glaxo Wellcome

Unknown

Safety and Effectiveness of Three Anti-HIV Drugs Combined in One Pill (Trizivir)

HIV Infections

United States
Genelabs Technologies

Completed

A Randomized Phase II Efficacy, Activity and Safety Study of GLQ223 Alone and in Combination With Zidovudine in Symptomatic HIV-Infected Patients Without Prior Treatment With GLQ223 or Trichosanthin

HIV Infections

United States
Schering-Plough

Completed

Phase III Ganciclovir +/- rGM-CSF for AIDS-Related CMV Retinitis

HIV Infections | Cytomegalovirus Retinitis

United States
Merck Sharp & Dohme LLC

Completed

Effect of Indinavir Plus Two Other Anti-HIV Drugs on Blood Clotting in HIV-Positive Males With Hemophilia

HIV Infections | Hemophilia A

Canada, United States
Dupont Merck

Completed

A Study of Three Different Anti-HIV Drug Combinations in HIV-Infected Patients

HIV Infections

United States, Puerto Rico
Triangle Pharmaceuticals

Completed

A Study of MKC-442 in Combination With Other Anti-HIV Drugs

HIV Infections

United States
Agouron Pharmaceuticals

Completed

Safety and Effectiveness of Treating HIV-Positive Patients With an HIV Vaccine (Remune)

HIV Infections

United States
Cellerix

Unknown

Autologous Stem Cells Derived From Lipoaspirates for the Non-Surgical Treatment of Complex Perianal Fistula

Anal Fistula

Spain
Pharmacia

Completed

Rifabutin Therapy for the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in AIDS Patients With CD4 Counts = or < 200: A Double-Blind, Placebo-Controlled Trial

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States, Canada
American National Red Cross

Completed

A Pilot Study to Obtain Preliminary Information Regarding the Efficacy and Safety of the Combination of Immune Globulin and Ganciclovir as Compared to Ganciclovir Alone in the Treatment of Sight-Threatening CMV Retinitis in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States
Pharmacia

Completed

A Three-Arm Comparative Trial for the Treatment of MAC Bacteremia in AIDS: A Clarithromycin/Ethambutol Regimen Containing Rifabutin (450 Mg) or Rifabutin (300 Mg) or Placebo

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Pharmacia and Upjohn

Completed

A Double-Blind, Randomized, Comparative Study of Delavirdine Mesylate (U-90152S) in Combination With Didanosine (ddI) Versus ddI Alone in HIV-1 Infected Individuals With CD4 Counts of <= 300/mm3

HIV Infections

United States, Puerto Rico
Gilead Sciences

Completed

A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Adefovir Dipivoxil When Added to Standard Antiretroviral Therapy for the Treatment of HIV-Infected Patients With CD4 Cell Counts >= 200/mm3

HIV Infections

United States
Glaxo Wellcome

Completed

A Comparison of Two Multi-Drug Therapies in HIV-Infected Patients Who Have Never Received Anti-HIV Treatment

HIV Infections

United States
Merck Sharp & Dohme LLC
Agouron Pharmaceuticals

Completed

A Study on the Safety and Effectiveness of Twice-Daily Nelfinavir Plus Twice-Daily Indinavir Plus Efavirenz in HIV-Positive Patients Who Have Never Taken Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) or Protease Inhibitors

HIV Infections

United States
Pharmacia and Upjohn

Completed

A Study to Find the Best Dosing Schedule for Delavirdine, Zidovudine, and Indinavir in HIV-Positive Patients

HIV Infections

United States
Hoechst Marion Roussel

Completed

The Safety and Effectiveness of HBY 097 Used With or Without AZT in HIV-Infected Patients Who Have Mild or No Symptoms

HIV Infections

United States
Triangle Pharmaceuticals

Suspended

A Comparison of Emtricitabine and Abacavir Used in a Three-Drug Combination in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States
Hoffmann-La Roche

Completed

A Comparison of Three Anti-HIV Drug Combinations Containing Saquinavir Soft Gelatin Capsules Used in HIV-1 Infected Patients

HIV Infections

United States, Puerto Rico, Spain, Germany, Italy, United Kingdom
Glaxo Wellcome

Completed

Safety and Effectiveness of a Combination Anti-HIV Drug Treatment

HIV Infections

United States
National Center for Research Resources (NCRR)

Unknown

Hormone Replacement Therapy and Insulin Action: A Double-Blind, Parallel, Placebo-Controlled Hormone Intervention Study in Postmenopausal Women

Menopause

United States
Hoffmann-La Roche
Trimeris

Completed

T-20 With Anti-HIV Combination Therapy for Patients With Prior Anti-HIV Drug Treatment and/or Drug Resistance to Each of the Three Classes of Approved Anti-HIV Drugs

HIV Infections

United States, Canada
Triangle Pharmaceuticals

Completed

Comparing FTC and Lamivudine in HIV-Infected Patients on a Stable Anti-HIV Drug Combination

HIV Infections

United States
Boehringer Ingelheim

Completed

The Safety and Effectiveness of Nevirapine Plus Lamivudine Plus Other Anti-HIV Drugs

HIV Infections

United States
Merck Sharp & Dohme LLC

Completed

A Study of Indinavir Sulfate Given Together With Stavudine to HIV-Positive Patients

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Study to Evaluate the Effect of Anti-HIV Therapy on Lean Tissue (Muscle) in HIV-Positive Patients

HIV Infections

United States, Puerto Rico
Hoffmann-La Roche

Completed

A Phase IIIB Open-Label, Comparative Study to Evaluate Saquinavir Soft Gel Capsule (SGC) Treatment in Combination With Other Antiretrovirals in HIV-1 Infected Antiretroviral-Naive Patients

HIV Infections

United States
Glaxo Wellcome

Completed

The Safety and Effectiveness of 524W91

HIV Infections

United States
National Institute of Dental and Craniofacial Research...
Washington University School of Medicine

Completed

Phase III Randomized Study of the Effect of Postmenopausal Estrogen Replacement Therapy on Alveolar Bone Loss

Osteoporosis
Glaxo Wellcome

Completed

A Study of 1592U89 in Combination With Protease Inhibitors in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States
Boehringer Ingelheim

Completed

The Safety and Effectiveness of Nevirapine Plus Nelfinavir in HIV-1 Infected Patients Who Have Taken Stavudine

HIV Infections

United States

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