Search clinical trials for: Immunologic response

Total 52665 results

National Center for Research Resources (NCRR)
Crohn's and Colitis Foundation

Completed

A Pharmacokinetic Study to Determine the Oral Bioavailability of Methotrexate in Patients With Inflammatory Bowel Disease

Inflammatory Bowel Disease

United States
National Institute of Allergy and Infectious Diseases...

Completed

Treatment of Acute HIV Infection to Preserve Immune Function

HIV Infections

United States
Gilead Sciences

Unknown

Tenofovir Disoproxil Fumarate in HIV-Infected Patients Who Have Not Had Success With Other Anti-HIV Drug Combinations

HIV Infections

United States
National Center for Research Resources (NCRR)
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Phase I/II Study of High-Dose Acyclovir for Central Nervous System or Disseminated Neonatal Herpes Simplex Virus Infection

Herpes Simplex
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

A Third-Party Blinded, Placebo Controlled Comparative Study of AS-101 Administered Intravenously in HIV Positive Patients With Advanced Disease

HIV Infections

Brazil
Hoechst Marion Roussel

Completed

A Study of MDL 28,574A in HIV-Infected Patients

HIV Infections

United States
R W Johnson Pharmaceutical Research Institute

Completed

A Double-Blind Study to Evaluate the Safety and Pharmacokinetics of L-Ofloxacin (RWJ 25213) in Subjects With HIV Infection

HIV Infections

United States
Columbia Research Laboratories

Completed

The Safety and Effectiveness of SPC3 in HIV-1 Infected Patients

HIV Infections

United States
Glaxo Wellcome

Completed

The Safety and Effectiveness of Zidovudine Plus Lamivudine, Used With and Without 1592U89, in HIV-1 Infected Children Who Have Taken Anti-HIV-1 Drugs

HIV Infections

United States
Fisons

Completed

The Safety and Effectiveness of Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS Who Have Had PCP Before

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Hoffmann-La Roche

Completed

A Study of Saquinavir Used Alone or in Combination With Other Anti-HIV Drugs in HIV-Infected Patients

HIV Infections

United States
Pfizer

Completed

A Comparison of the Safety and Effectiveness of Fluconazole or Clotrimazole in the Treatment of Fungal Infections of the Mouth and Throat in Patients With AIDS

HIV Infections | Candidiasis, Oral

United States
ViRx

Completed

ABT-378/Ritonavir and Efavirenz in HIV-Infected Patients Who Have Taken More Than One Protease Inhibitor in the Past

HIV Infections

United States
Glaxo Wellcome

Completed

A Phase III, Randomized, Double-Blind, Multicentre Study to Evaluate the Safety and Efficacy of 1592U89 in Patients With AIDS Dementia Complex

HIV Infections | AIDS Dementia Complex

United States, Canada
Glaxo Wellcome

Completed

Treatment of AIDS and AIDS Related Complex. Part-1- Treatment of Patients With ARC (AZT Vs. Placebo)

HIV Infections

United States
Fairview University Medical Center

Completed

Study of Allogeneic Bone Marrow Transplantation Using Matched, Related Donors in Patients With Nonmalignant Hematologic Disorders

Neutropenia | Sickle Cell Anemia | Red-Cell Aplasia, Pure | Thalassemia Major

United States
Sandoz

Completed

A Multicenter Placebo-Controlled Dose Titration Study to Evaluate the Efficacy and Safety of Sandostatin (SMS 201-995) in the Treatment of Patients With Acquired Immunodeficiency Related Diarrhea

HIV Infections | Diarrhea

United States
Gilead Sciences

Completed

A Study on the Safety and Effectiveness of Adefovir Dipivoxil in Combination With Anti-HIV Therapy (HAART) in HIV-Positive Patients

HIV Infections

United States, United Kingdom, Germany, Canada, France
Agouron Pharmaceuticals

Terminated

Safety and Effectiveness of 3 Anti-HIV Treatments in Patients Who Have Failed Previous Treatments Containing Nelfinavir

HIV Infections

United States
Chiron Corporation

Completed

A Phase I, Observer-Blind, Placebo-Controlled Study of the Chiron Vaccine HIV p24/MF59 Administered to Healthy HIV-Seronegative Adults

HIV Infections | HIV Seronegativity

United States
Rockefeller University

Completed

Immunomodulation of HIV-1 Infected Individuals With PEG-Interleukin-2

HIV Infections

United States
Glaxo Wellcome

Completed

Safety and Effectiveness of Giving Two Nucleoside Reverse Transcriptase Inhibitors Alone or in Combination With 141W94 to HIV-Infected Children Who Have Never Received Protease Inhibitors

HIV Infections

United States
Hoffmann-La Roche

Completed

A Study of ddC in Patients With AIDS or Advanced AIDS-Related Complex (ARC) Who Have Not Had Success With Zidovudine (AZT)

HIV Infections

United States
Community Research Initiative of New England

Completed

An Evaluation of Pentoxifylline in HIV-Positive Persons With Symptomatic HIV Infection and a Karnofsky Score > 40 Percent and < 100 Percent

HIV Infections

United States
National Center for Research Resources (NCRR)

Unknown

Effects of Home Visits on Medication Adherence in Children and Youth With HIV

HIV Infections

United States
Sandoz

Completed

A Phase I/II Pilot Study of Simultaneously Administered Rhu GM-CSF ( CHO Cell ) and Azidothymidine ( AZT ) in Patients With Severe HIV Infection and Leukopenia: Pharmacokinetics and Feasibility

HIV Infections | Cytopenias

United States
National Eye Institute (NEI)

Unknown

The Safety and Efficacy of a Tumor Necrosis Factor Receptor Fusion Protein on Uveitis Associated With Juvenile Rheumatoid Arthritis

Uveitis | Arthritis, Juvenile Rheumatoid

United States
Sandoz

Completed

A Phase I/II Trial to Assess the Safety and Tolerance of Escalating Doses of a Human Anti-Cytomegalovirus Monoclonal Antibody (SDZ MSL-109) in Patients With the Acquired Immunodeficiency Syndrome and CMV Retinitis

HIV Infections | Cytomegalovirus Retinitis

United States
Ortho Pharmaceuticals

Completed

A Double-Blind, Placebo-Controlled Study With Open-Label Follow-Up To Determine the Safety and Efficacy of r-HuEPO in AIDS Patients With Anemia Induced by Their Disease and AZT Therapy

HIV Infections | Cytopenias

United States
Lederle Laboratories

Completed

An Ascending, Single Oral Dose Pharmacokinetic Study of 3'-Deoxy-3'-Fluorothymidine (FLT) in Asymptomatic Human Immunodeficiency Virus (HIV)-Infected Subjects

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I Randomized Dose/Formulation Comparison Study of SC-52151

HIV Infections

United States
National Center for Research Resources (NCRR)
Tulane University School of Medicine

Completed

Phase III Randomized Study of High Vs Standard Dose of Interferon Alfa for Chronic Hepatitis C

Hepatitis C
Pfizer

Completed

Multicenter Comparison of Fluconazole (UK-49,858) and Amphotericin B as Maintenance Treatment for the Prevention of Relapse of Cryptococcal Meningitis in Patients With Acquired Immunodeficiency Syndrome

HIV Infections | Meningitis, Cryptococcal

United States, Canada
Otsuka America Pharmaceutical

Completed

A Study of Multiple Doses of Vesnarinone in Advanced HIV Disease

HIV Infections

United States
Astra USA

Completed

An Open Study of Foscarnet Treatment of Acyclovir-Resistant Herpes Simplex Virus in Patients With the Acquired Immunodeficiency Syndrome and Other Immunodeficiencies

HIV Infections | Herpes Simplex

United States
Rhone-Poulenc Rorer

Completed

Open-Label "Compassionate" Use Study of Spiramycin for the Treatment of Diarrhea Due to Chronic Cryptosporidiosis in Immunocompromised Patients

HIV Infections | Cryptosporidiosis

United States
NeurogesX

Terminated

An Open-Label Extension Study of NGX-4010 for the Treatment of Neuropathic Pain

HIV Infections | Pain | Diabetes Mellitus | Diabetic Neuropathies | Peripheral Nervous System Diseases | Neuralgia | Herpes Zoster | Polyneuropathies
Glaxo Wellcome

Completed

A Pilot Study of 566C80 for the Salvage Treatment of Toxoplasmic Encephalitis in Patients Infected With the Human Immunodeficiency Virus (HIV) Who Have Failed or Are Intolerant of Pyrimethamine-Sulfadiazine

HIV Infections | Toxoplasmosis, Cerebral

United States, Canada
Anderson Clinical Research
Hoechst Marion Roussel

Completed

Tolerance, Safety, and Activity of Rifapentine Alone and in Combination Therapy in AIDS Patients With Mycobacterium Avium Complex Bacteremia.

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Immunobiology Research Institute

Completed

A Study of Timunox (Thymopentin) in HIV-Infected Patients Receiving Other Anti-HIV Drugs

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Genentech, Inc.

Completed

A Phase I Study of the Safety and Pharmacokinetics of Recombinant CD4 (rCD4) in Infants and Children Infected With or at Risk for HIV Infection

HIV Infections

United States
Glaxo Wellcome

Completed

A Study of Azidothymidine (AZT) in the Treatment of HIV Infection in Patients Receiving a Bone Marrow Transplant

HIV Infections | Lymphoma, Non-Hodgkin

United States
National Institute of Allergy and Infectious Diseases...
Genentech, Inc.

Completed

A Phase I Multicenter Study of the Safety and Immunogenicity of MN rgp120/HIV-1 Vaccine Given Either Alone or in Combination With IIIB rgp120/HIV-1 Vaccine in Healthy Adult Subjects (NOTE: Original Study Extended ONLY for Patients Previously Enrolled on VEU 009)

HIV Infections

United States
Centaur Pharmaceuticals

Unknown

Safety and Effectiveness of Giving CPI-1189 to HIV-Infected Patients With AIDS Dementia

HIV Infections

United States
Gilead Sciences

Completed

Tenofovir Disoproxil Fumarate (TDF) in HIV-1 Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States
Merck Sharp & Dohme LLC

Completed

Safety and Effectiveness of an Anti-HIV Drug Combination in HIV-Positive Patients Who Have Failed Previous Treatment With Protease Inhibitors

HIV Infections

United States
PPD

Unknown

Differences Between Women and Men Taking a Combination of Indinavir, Ritonavir, Enteric-Coated Didanosine, and Stavudine Who Previously Took Anti-HIV Drugs

HIV Infections

United States, Puerto Rico
Glaxo Wellcome

Unknown

Comparison of GW433908 and Nelfinavir in HIV Patients Who Have Not Had Antiretroviral Therapy

HIV Infections

United States
Triangle Pharmaceuticals

Completed

A Randomized, Double-Blind Study of MKC-442 Combined With Viracept in Patients Who Are Epivir + Retrovir Experienced and Are Protease Inhibitor- and Non-Nucleoside Reverse Transcriptase Inhibitor-Naive

HIV Infections

United States
Unimed Pharmaceuticals

Completed

A Study of Nitazoxanide in the Treatment of AIDS-Related Diarrhea

HIV Infections

United States

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