Clinical Trials Sponsored by Duke University

Total 222172 results

Duke University

Completed

Markers of Alzheimers Disease After Propofol or Isoflurane Anesthesia (MAD-PIA)

General Anesthesia

United States
Duke University

Terminated

Incisional Negative Pressure Wound Therapy

Spinal Deformity

United States
Duke University

Terminated

Effects of Sildenafil on Choroidal Thickness in AMD

Age-related Macular Degeneration

United States
Duke University

Terminated

Mechanistic Assessment of the Properties of Saxagliptin in Subjects Undergoing Coronary Artery Bypass Graft Surgery (MAPSS)

Cardiovascular Disease | Type 2 Diabetes Mellitus

United States
Duke University

Completed

Standard Percutaneous Nephrolithotomy Percutaneous Nephrolithotomy (PNL) Versus Tubeless PNL Versus Tubeless Stentless PNL

Nephrolithotomy

United States
Duke University

Completed

Cognitive Behavioral Treatments for Depression in Chronic Illness

Major Depression

United States
Duke University

Completed

Efficacy and Safety of Temazepam in HIV Seropositive Patients With Insomnia

Insomnia
Duke University

Completed

Ehealth: Second Life Impacts Diabetes Education & Self-Management (SLIDES)

Type 2 Diabetes

United States
Duke University

Completed

Efficacy of Percussive Ventilation Therapy (MetaNeb ®) Compared With Mucolytic Agents for Atelectasis in the Mechanically Ventilated Pediatric Patient

Atelectasis
Duke University

Completed

Vasospasm in Pediatric Traumatic Brain Injury (PTBI)

Brain Injury

United States
Duke University

Completed

Supplemental Nicotine Administration for Smoking Cessation in Posttraumatic Stress Disorder (PTSD)

Smoking Cessation

United States
Duke University

Terminated

Automated MEdical Record Driven Implantable CArdioverter-defibrillator Heart Failure Trial (AMERICA-HF) (AMERICA-HF)

Heart Failure

United States
Duke University

Completed

GENErating Behavior Change, An Integrative Health Coaching and Genetic Risk Testing Pilot

Coronary Heart Disease Risk
Duke University

Completed

Efficacy and Safety of the DASH Diet in Adults With Moderate Chronic Kidney Disease: Pilot Study

Hypertension | Chronic Kidney Disease

United States
Duke University

Completed

Topical Bimatoprost Effect on Androgen Dependent Hair Follicles

Androgenetic Alopecia | Male Pattern Hair Loss
Duke University

Completed

Retisert and Cataract Surgery in Patients With Severe Uveitis

Posterior Uveitis | Intermediate Uveitis

United States
Duke University

Terminated

Inhaled Aerosolized Prostacyclin for Pulmonary Hypertension Requiring Inhaled Nitric Oxide

Pulmonary Hypertension
Duke University

Completed

An Evaluation of the Effectiveness of Local Anesthetics Used During Intravenous Catheter Insertion

IV Insertion Pain
Duke University

Completed

Reduced Intensity Conditioning for Umbilical Cord Blood Transplant in Pediatric Patients With Non-Malignant Disorders

Hemoglobinopathies | Thalassemia | Lysosomal Storage Disease | Immunodeficiencies | Inborn Errors of Metabolism | Sickle Cell | Non Malignant Disorders | Congenital Marrow Failures

United States
Duke University

Terminated

Pilot Study of Interferon Alfa for Patients Who Have Received Cancer Vaccines

Cancer
Duke University

Completed

Intensive Induction Therapy Followed by High Dose Chemo and BM Transplant for Mantle Cell Lymphoma

Mantle Cell Lymphoma
Duke University

Withdrawn

Effect of Dexmedetomidine Upon Sleep Postoperatively

Sleep

United States
Duke University

Terminated

A Research Pilot Study in Healthy Volunteers to Evaluate Biomarkers for Novel Anticancer Treatments

Healthy

United States
Duke University

Completed

Pilot Study of Duloxetine in Psychological Resilience

Major Depressive Disorder

United States
Duke University

Completed

Hydroxyurea to Prevent Stroke in Children With Sickle Cell Anemia and Elevated TCD Flow Velocity

Stroke

United States
Duke University

Terminated

Computerized Cognitive Training for Childhood Cancer Survivors

Primary Brain Tumor

United States
Duke University

Completed

The Effect of Depth of Anesthesia as Measured by Bispectral Index (BIS) on Emergence Agitation in Children

Emergence Agitation

United States
Duke University

Completed

Infection Rates of Myeloablative Allo SCT Recipients Receiving Neutropenic Diets Versus Non-Neutropenic Diets

Hematologic Malignancies

United States
Duke University

Completed

Erythropoietin Resistance in Anemia of Chronic Kidney Disease

Anemia | Kidney Failure | Erythropoietin

United States
Duke University

Completed

Diagnostic Yield of Vitreous Biopsy in Sarcoid Uveitis

Sarcoidosis-associated Ocular Inflammation

United States
Duke University

Completed

Monoclonal Antibody Therapy in Treating Patients With Recurrent Gliomas

Brain and Central Nervous System Tumors

United States
Duke University

Terminated

Polycystic Ovarian Syndrome: Impact of Flaxseed Supplementation

Polycystic Ovarian Syndrome

United States
Duke University

Completed

Wheeled Mobility in Everyday Life (RERC-4a)

Arthritis | Lung Disorder | Chronic Heart Disorder

United States
Duke University

Terminated

Functional Imaging of Tumor and Normal Tissue (FITT)

Head and Neck Cancer

United States
Duke University

Completed

PARTNER Recruitment and Brief Intervention Pilot Study (PARTNER)

Alcohol Abuse

United States
Duke University

Not yet recruiting

Prospective Registry of Ocular Melanoma Eye Plaque brachyTherapy Patients (PROMPT)

Ocular Melanoma
Duke University

Not yet recruiting

RECOVER-SLEEP: Platform Protocol, Appendix_B (CPSD)

Sleep Disturbance | Long COVID | Long COVID-19
Duke University

Not yet recruiting

RECOVER-SLEEP: Platform Protocol, Appendix_A (Hypersomnia)

Long COVID | Long COVID-19 | Hypersomnia
Duke University

Not yet recruiting

A Feasibility Study of Supplemental Oxygen to Improve Pulmonary Hypertension in People With Intradialytic Hypoxemia (SOPHIE)

Pulmonary Hypertension

United States
Duke University

Recruiting

Preventing Failed Extubations (PreFIX)

Mechanical Ventilation Complication | Weaning Failure

United States
Duke University

Not yet recruiting

Biobanking Upper Gastrointestinal Tumors to Evaluate Response (BURGER With BACON)

GastroEsophageal Cancer

United States
Duke University

Recruiting

A Multicenter Trial to Identify Optimal Atezolizumab Biomarkers in the Setting of Recurrent Glioblastoma. The MOAB Trial (MOAB)

Recurrent Glioblastoma

United States
Duke University

Not yet recruiting

Project HOPES: Healthy Options for Pain and Ending Smoking. A Program for Cancer Survivors.

Smoking Cessation | Pain

United States
Duke University

Recruiting

Medication Adherence in Rheumatic Diseases

Chronic Rheumatic Diseases

United States
Duke University

Recruiting

Directed Topical Drug Delivery for Treatment for PASC Hyposmia

Post Acute Sequelae Covid-19 Hyposmia

United States
Duke University

Recruiting

Eat Well Produce Benefit for Diabetes and Food Insecurity

Diabetes Mellitus | Food Insecurity

United States
Duke University

Recruiting

External Body Pressure in Heart Failure With Preserved Ejection Fraction

Heart Failure, Diastolic

United States
Duke University

Recruiting

A Feasibility Trial of OCM Supplements for the Treatment of NAFLD

NAFLD

United States
Duke University

Recruiting

Generating Evidence in ECMO Ventilation Strategies (GENIE-Vent)

ARDS | Acute Respiratory Failure

United States
Duke University

Recruiting

Effectiveness of Outpatient Intravenous Diuretic Therapy for Treatment of Worsening Heart Failure (OUTPATIENT-WHF)

Heart Failure

United States

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