Search clinical trials for: FGFR Mutations
Total 1396 results
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UNICANCERCompletedLetrozole in Preventing Breast Cancer in Postmenopausal Women With a BRCA1 or BRCA2 Mutation (LIBER)Breast Cancer | Hereditary Breast/Ovarian Cancer (brca1, brca2) | brca1 Mutation Carrier | brca2 Mutation CarrierFrance
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Academic and Community Cancer Research UnitedNational Cancer Institute (NCI)Active, not recruitingMetastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Stage IIIA Colorectal Cancer AJCC v8 | Stage IIIB Colorectal Cancer AJCC v8 | Stage IIIC Colorectal Cancer AJCC v8 and other conditionsUnited States
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Atsena Therapeutics Inc.Active, not recruitingLeber Congenital Amaurosis | LCA | LCA1United States
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MedSIRGlaxoSmithKlineCompletedBreast Cancer | Breast Cancer MetastaticSpain
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European Organisation for Research and Treatment...Active, not recruitingNon Small Cell Lung CancerNetherlands, Spain, France, United Kingdom, Norway, Jordan, Belgium
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University of CologneCompletedBronchial NeoplasmsSpain, Germany
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Spectrum Pharmaceuticals, IncSuspended
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Faeth TherapeuticsActive, not recruitingAdvanced Solid Tumor | PIK3CA Mutation | PTEN Loss of Function MutationUnited States
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Sidney Kimmel Comprehensive Cancer Center at Johns...Clovis Oncology, Inc.Active, not recruitingProstate Cancer MetastaticUnited States
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Sidney Kimmel Comprehensive Cancer Center at Johns...National Cancer Institute (NCI); BeiGeneCompletedRecurrent Glioblastoma | Recurrent WHO Grade III Glioma | Recurrent WHO Grade II Glioma | IDH1 Mutation | IDH2 MutationUnited States
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Debiopharm International SACaris Life Sciences; Optimal Research (Just In Time sites)TerminatedSolid TumorUnited States, Spain, Austria, Czechia, Denmark, Russian Federation, United Kingdom, Greece, Norway, Korea, Republic of, France, Taiwan, Netherlands, Bulgaria, Finland, Ukraine, Australia, Brazil, Croatia, Philippines, Poland, Rom... and more
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Centre Hospitalier Universitaire de NīmesActive, not recruitingMyeloproliferative DisorderFrance
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Avidity Biosciences, Inc.Enrolling by invitationDuchenne Muscular Dystrophy | DMD | Exon 44 | DuchenneUnited States
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Novartis PharmaceuticalsTerminatedCarcinoma, Non-Small-Cell LungBelgium, Germany, United States, Canada, France, Italy, Japan, Korea, Republic of, Spain
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University of VirginiaActive, not recruitingReal-Time Monitoring of Symptoms in Lung Cancer Patients Receiving Oral Targeted Therapies (Lung001)Lung Cancer | ALK Gene Mutation | MET Gene Mutation | KRAS Mutation-Related Tumors | RET Gene Mutation | EGFR Gene Mutation | EGFR | ROS1 Gene Mutation | BRAFUnited States
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JS InnoPharm, LLCSuspended
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Arog Pharmaceuticals, Inc.CompletedNewly Diagnosed AML With FLT3 Activating MutationsUnited States
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ImmVira Pharma Co. LtdSuspendedMelanoma | Malignant MelanomaUnited States
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Vanderbilt-Ingram Cancer CenterNational Cancer Institute (NCI)Active, not recruitingMetastatic Breast CancerUnited States
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Ambrx, Inc.CompletedBreast Neoplasms | Solid Tumors | Gastric NeoplasmUnited States, Australia
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Ayala Pharmaceuticals, Inc,CompletedAdenoid Cystic CarcinomaUnited States, Canada, France, United Kingdom, Israel, Netherlands
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University of Michigan Rogel Cancer CenterMemorial Sloan Kettering Cancer Center; University of California, San FranciscoActive, not recruitingSolid Tumor | Metastatic Cancer | Metastatic Castration Resistant Prostate CancerUnited States
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Arog Pharmaceuticals, Inc.CompletedPhase II Study of Crenolanib in Subjects With Relapsed/Refractory AML With FLT3 Activating MutationsRelapsed or Refractory Acute Myeloid Leukemia With FLT3 Activating MutationsUnited States
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CelgeneActive, not recruitingLeukemia, Myeloid, AcuteUnited States, France, Italy, Korea, Republic of, Spain, United Kingdom, Australia, Canada, Germany, Netherlands, Portugal, Switzerland, Belgium, Sweden
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Spark TherapeuticsCompletedChoroideremia | CHM (Choroideremia) Gene MutationsUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)CompletedAcute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Therapy-Related Acute Myeloid Leukemia and other conditionsUnited States
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Spark TherapeuticsActive, not recruitingConfirmed Biallelic RPE65 Mutation-associated Retinal DystrophyUnited States
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M.D. Anderson Cancer CenterAstraZeneca; Mirati Therapeutics Inc.WithdrawnLung Cancer | Gastro-intestinal CancerUnited States
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Incyte CorporationActive, not recruitingGlioblastoma | Adult-type Diffuse GliomasUnited States, Spain, Italy, United Kingdom, Germany, Japan, France, Netherlands, Denmark
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Medical University of South CarolinaRain Oncology IncTerminated
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Blueprint Medicines CorporationActive, not recruitingNeoplasms | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Carcinoma, Non-Small-Cell Lung | Respiratory Tract Neoplasms | Carcinoma, Bronchogenic | Bronchial Neoplasms | Metastatic Lung Cancer | Antineoplastic Agents | Brain Metastases | Lung Neoplasm Malignant | EGFR... and other conditionsUnited States, Canada, Korea, Republic of, Japan, Taiwan
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI); National Comprehensive Cancer NetworkActive, not recruitingStage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Lung Non-Small Cell Carcinoma | Stage IV Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Recurrent Lung Non-Small Cell CarcinomaUnited States
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UNICANCERAstraZeneca; National Cancer Institute, France; Pierre Fabre LaboratoriesActive, not recruitingBreast Cancer | Head and Neck Cancer | Prostate Cancer | Cervix Cancer | Advanced Solid TumoursFrance
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Taiho Oncology, Inc.Active, not recruitingAdvanced Cholangiocarcinoma | FGFR2 Gene RearrangementsUnited States, Spain, United Kingdom, Australia, Taiwan, Italy, France, Korea, Republic of, Belgium, Japan, Thailand, Germany, Brazil, Peru, Portugal, Argentina, Hong Kong, Mexico, Netherlands, Poland
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Innostellar Biotherapeutics Co.,LtdActive, not recruitingInherited Retinal Dystrophy Associated With RPE65 MutationsChina
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University Health Network, TorontoActive, not recruitingSalivary Gland Cancer | Metastatic | Recurrent | AdvancedCanada
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National Cancer Center, JapanEisai Co., Ltd.Active, not recruitingAdvanced or Recurrent Solid Tumors | FGFR Gene AlterationsJapan
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)CompletedHigh-Frequency Microsatellite Instability | Mismatch Repair Gene Mutation | Mutation-Negative Lynch Syndrome | Mutation-Positive Lynch SyndromeUnited States
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Fusion Pharmaceuticals Inc.TerminatedBreast Cancer | Gastric Cancer | Colorectal Cancer | Ovarian Cancer | Lung Cancer | Advanced Solid Tumor | Head and Neck Squamous Cell Carcinoma | Liver Cancer | Bladder Carcinoma | Susceptible FGFR3 Genetic Alterations | FGFR3 | FGFR3 Overexpression | FGFR3 Receptor | FGFR3 Protein OverexpressionUnited States, Australia
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Basilea PharmaceuticaCompletedIntrahepatic Cholangiocarcinoma | Combined Hepatocellular and CholangiocarcinomaCanada, United States, Spain, Belgium, Italy, Korea, Republic of, Germany, Switzerland, France, United Kingdom, Ireland
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Endeavor Biomedicines, Inc.Active, not recruitingSolid Tumors With PTCH1 Loss-of-function MutationsUnited States
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University of Alabama at BirminghamNational Institutes of Health (NIH); Mereo BioPharmaCompletedEmphysema or COPD | Alpha-1 Antitrypsin Deficiency (AATD) | Pi*ZZ, Pi*SZ, Pi*Null, Another Rare Phenotype/Genotype Known to be Associated With Either Low or Functionally Impaired AAT Including F or I MutationsUnited States
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Stealth BioTherapeutics Inc.Active, not recruitingMitochondrial Diseases | Mitochondrial Myopathies | Mitochondrial Complex I Deficiency | Mitochondrial Pathology | Mitochondrial DNA Depletion | Mitochondrial DNA Mutation | Mitochondrial DNA Deletion | Mitochondrial Metabolism DefectSpain, United States, Italy, Netherlands, Australia, Germany, Hungary, New Zealand, Norway, United Kingdom
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St. Jude Children's Research HospitalCompletedInfluenza, HumanUnited States
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AstraZenecaCompletedNon Small Cell Lung CancerItaly, United States, Canada, Korea, Republic of, Japan, Taiwan, Hong Kong, Spain
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Wake Forest University Health SciencesNational Cancer Institute (NCI)TerminatedLymphoma | Multiple Myeloma | Solid Tumor | Malignant Neoplasm | Mutation AbnormalityUnited States
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University Children's Hospital TuebingenGerman Cancer Research Center; University Hospital Tuebingen; Universität TübingenCompletedPrimary/Relapsed Acute Lymphoblastic Leukemia (ALL) of Childhood, Adolescents and Young AdultsGermany
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University Hospital, ToursBiogenCompletedAmyotrophic Lateral SclerosisFrance
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Arog Pharmaceuticals, Inc.CompletedAcute Myeloid Leukemia With FLT3 Activating Mutations That Has Relapsed or Been Refractory After One or More Prior TherapiesUnited States