Search clinical trials for: HIV Protease Inhibitors

Total 73037 results

Cantonal Hospital of St. Gallen
Swiss National Science Foundation; Swiss HIV Cohort Study

Terminated

HIV - Monotherapy in Switzerland (MOST-ch) (MOST)

HIV Infections

Switzerland
Radboud University Medical Center
Kilimanjaro Christian Medical Centre, Tanzania; Kilimanjaro Clinical Research...

Completed

Neuropsychiatric Side Effects of Efavirenz in Children Living With HIV

Medication Adherence | Drug-Related Side Effects and Adverse Reactions | Child Behavior | Cognitive Symptom | Efavirenz

Tanzania
Janssen Scientific Affairs, LLC

Completed

A Single-arm, Open-label, Study to Assess the Pharmacokinetics of Darunavir and Ritonavir, Darunavir and Cobicistat, Etravirine, and Rilpivirine in HIV-1 Infected Pregnant Women

HIV Infections | Pregnancy | HIV

United States, Puerto Rico
AbbVie (prior sponsor, Abbott)

Completed

Study to Assess the Safety, Tolerability, Pharmacokinetics and Antiviral Activity of ABT-267 in HCV Infected Subjects

Chronic Hepatitis C Infection

United States
Ascletis Pharmaceuticals Co., Ltd.

Completed

Pharmacokinetics and Safety of Ravidasvir and Danoprevir/r in Healthy Volunteers China

Healthy
Willem Daniel Francois Venter
Medical Research Council, South Africa

Completed

Evaluation of Low-dose Darunavir in a Switch Study (DRV)

HIV Infections

South Africa
AbbVie (prior sponsor, Abbott)

Completed

A Study to Evaluate the Safety and Effect of Treatment With Experimental Antiviral Drugs in Combination With Peginterferon Alpha-2a and Ribavirin in People With Hepatitis C Virus Who Did Not Respond to Treatment in a Previous AbbVie/Abbott Combination Study

Chronic Hepatitis C
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Sitagliptin for Reducing Inflammation and Immune Activation

HIV-1 Infection

United States
Janssen Pharmaceutical K.K.

Completed

A Study to Evaluate the Pharmacokinetics (PK) of Darunavir (DRV) and Cobicistat (COBI) After a Single Oral Administration of Darunavir/Cobicistat Fixed-Dose Combination in Healthy Japanese Adult Participants

Healthy

Japan
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Evaluating Pharmacokinetic Interactions With Vaginal Ring Contraceptives and ART

HIV-1 Infection

United States, Peru, Puerto Rico, Brazil, Botswana, Kenya, South Africa, Thailand
AbbVie

Completed

Study to Evaluate the Efficacy and Safety of ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) in Japanese Adults With Subgenotype 1b Chronic Hepatitis C Virus (HCV) Infection (GIFT I)

Chronic Hepatitis C Infection
AbbVie (prior sponsor, Abbott)

Completed

A Study to Evaluate ABT-450 With Ritonavir (ABT-450/r) and ABT-267 in Japanese Adults With Chronic Hepatitis C Virus Infection

Chronic Hepatitis C Infection
Bristol-Myers Squibb

Completed

PRINCE: Study of Atazanavir (ATV)/Ritonavir (RTV) (PRINCE1)

HIV Infections

Thailand, Chile, Peru, Brazil, Mexico, South Africa
American Society of Hematology

Active, not recruiting

The American Society of Hematology (ASH) Research Registry: A Multicenter Research Registry of Patients With Hematologic Disease

Benign and Malignant Hematologic Diseases

United States
St Stephens Aids Trust
ViiV Healthcare

Completed

The Pharmacokinetics of Dolutegravir, Darunavir/Cobocistat When Co-administered in Healthy Volunteers (SSAT073)

HIV

United Kingdom
Assiut University

Completed

Evaluation of Treatment of Chronic HCV Patients in Chronic Kidney Disease Versus End Stage Renal Disease Patients

Hepatitis C

Egypt
Parc de Salut Mar

Completed

Impact of Antiviral Therapy on Gastroesophageal Varices.

Cirrhosis | Chronic Hepatitis C
Hepa C

Completed

Effectiveness, Safety and Clinical Outcomes of Paritaprevir/Ombitasvir/r+Dasabuvir 8 Weeks (3D8)

Hepatitis C Infection

Spain
Washington University School of Medicine

Completed

Effectiveness of Sitagliptin for HIV Insulin Resistance and Inflammation

Inflammation | Cardiovascular Disease | Macrophage Infiltration

United States
Bristol-Myers Squibb

Completed

Safety Sudy of Atazanavir Boosted With Ritonavir in the Treatment of HIV Infection in Pediatric Patients

HIV, Pediatric

United States, Brazil, Chile, Mexico, Peru, South Africa, Argentina, Russian Federation
Yongtao Sun, MD, PhD
China Medical University, China; Beijing YouAn Hospital; Zhejiang University; Tang-Du... and other collaborators

Unknown

Early cART and cART in Combination With Autologous HIV-1 Specific Cytotoxic T Lymphocyte (CTL) Infusion in The Treatment of Acute HIV-1 Infected Adults

Acute HIV Infection

China
Janssen-Cilag S.p.A.

Completed

Study in HIV1-Positive, Virosuppressed Patients Currently inTreatment With Ritonavir-Boosted Protease Inhibitors (PI/r) Starting Cobicistat-Boosted Darunavir (DRV/c - Rezolsta) (STORE)

Human Immunodeficiency Virus
ViiV Healthcare
GlaxoSmithKline

Completed

Fosamprenavir Versus Other Protease Inhibitors

Infection, Human Immunodeficiency Virus I

United States, Puerto Rico
St Stephens Aids Trust

Completed

Cardiovascular Risk in HIV Patients Switching From a Boosted Protease Inhibitor (PI) to Dolutegravir (DTG)

HIV

Germany, Spain, France, United Kingdom, Belgium, Italy
Hoffmann-La Roche

Completed

A Study of Saquinavir/Ritonavir in Liver-Impaired Patients With HIV Infection.

HIV Infections

Canada, United States, Puerto Rico
First Affiliated Hospital of Zhejiang University
Ascletis Pharmaceuticals Co., Ltd.

Completed

Bioequivalence Study of Ritonavir Versus NORVIR in Healthy Chinese Subjects (RTV)

Healthy Volunteer

China
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Safety and Effectiveness of Lopinavir/Ritonavir in Individuals Who Have Failed Prior HIV Therapy

HIV Infections

Malawi, South Africa, India, Tanzania, Thailand
Fundación FLS de Lucha Contra el Sida, las Enfermedades...

Completed

Clinical Trial to Evaluate Drug-drug Interactions Between Darunavir/Cobicistat and Etravirine in Hiv- Infected Patients

HIV-1 Infection

Spain
AbbVie

Completed

A Study to Evaluate the Safety and Antiviral Effect of ABT-450/Ritonavir and ABT-530 Coadministered With and Without Ribavirin in Adults With Genotype 3 Hepatitis C (HCV) Infection

Chronic Hepatitis C | Hepatitis C Virus
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

Rifampin-Based Tuberculosis Treatment Versus Rifabutin-Based Tuberculosis Treatment in Persons With HIV

HIV Infection | Tuberculosis

Peru, Brazil, South Africa, Haiti, Kenya
Dartmouth-Hitchcock Medical Center

Withdrawn

Dose Escalation Study of Nelfinavir Plus MLN9708 in Patients With Advanced Solid Tumors or Lymphoma

Neoplasms | Lymphoma

United States
AbbVie (prior sponsor, Abbott)

Completed

Real-life Effectiveness of the Kaletra Adherence Support Assistance (KASA) Program

Human Immunodeficiency Virus Infection
ViiV Healthcare
GlaxoSmithKline

Completed

A Phase 1 Antiretroviral Drug-Drug Interaction Study in Healthy Volunteers (DDI)

Infection, Human Immunodeficiency Virus

United States
Ain Shams University

Unknown

Efficacy and Safety of Qurevo Plus Ribavirin Based Therapy for Hepatitis C With or Without Cirrhosis in Haemodialysis Patients

Chronic Hepatitis c

Egypt
Ascletis Pharmaceuticals Co., Ltd.

Completed

Pharmacokinetics and Safety of ASC16 Tablets in Healthy Volunteers in China

HCV

China
ViiV Healthcare
GlaxoSmithKline

Completed

Dolutegravir Compared to Darunavir/Ritonavir , Each in Combination With Dual Nucleoside Reverse Transcriptase Inhibitors (NRTIs) in ART-naive Subjects (FLAMINGO)

Infection, Human Immunodeficiency Virus

Spain, France, Germany, United States, Italy, Romania, Russian Federation, Switzerland, Puerto Rico
Institut de Médecine et d'Epidémiologie Appliquée...

Completed

Evaluation of the Efficacy and Safety Between Two Antiretroviral Regimens, in HIV-1-infected Treatment-naïve Subjects With Low CD4 Counts (DATA)

HIV-1 Infection | Immunosuppression-related Infectious Disease

France
St Stephens Aids Trust
Bristol-Myers Squibb

Terminated

Pharmacokinetic Effect of Evotaz/Microgynon Co-administration

HIV

United Kingdom
AbbVie

Completed

A Study of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir With or Without Sofosbuvir and Ribavirin in Direct-Acting Antiviral Agent Treatment-Experienced Adults With Chronic Hepatitis C Virus Infection

Chronic Hepatitis C Infection
University of California, Los Angeles
Los Angeles County Department of Public Health; Los Angeles LGBT Center; The... and other collaborators

Completed

Interventions for HIV Negative Men and Women Who Have High-risk Suspected Exposure to HIV

HIV Infections | HIV Prevention

United States
Washington University School of Medicine

Completed

LAAM-HAART PET Imaging

Healthy Volunteers

United States
AbbVie

Terminated

A Study to Evaluate the Safety and Efficacy of Ombitasvir/Paritaprevir/r With or Without Dasabuvir and With or Without Ribavirin in Chronic Hepatitis C Virus Genotype 1 or 4 Infected Adults With Successfully Treated Early Stage Hepatocellular Carcinoma (GEODE - I)

Chronic Hepatitis C Infection
Bayer

Completed

Interaction With HIV Antiretroviral Agents

HIV-DDI

United States
AbbVie (prior sponsor, Abbott)

Completed

A Follow up Study Designed to Obtain Long Term Data on Participants Who Either Achieved a Sustained Virologic Response or Did Not Achieve a Sustained Virologic Response in an AbbVie Sponsored Hepatitis C Study

Hepatitis C
Masonic Cancer Center, University of Minnesota
Susan G. Komen Breast Cancer Foundation

Completed

Ritonavir and Its Effects on Biomarkers in Women Undergoing Surgery for Newly Diagnosed Breast Cancer

Breast Cancer

United States
AbbVie

Completed

Ombitasvir/Paritaprevir/Ritonavir With or Without Dasabuvir in Adults With Genotype 1a or Genotype 4 Chronic Hepatitis C Virus (HCV) Infection, With Severe Kidney Impairment or End Stage Kidney Disease

Hepatitis C Virus (HCV)
Janssen-Cilag International NV

Completed

A Clinical Trial Comparing the Efficacy of Darunavir/Ritonavir Monotherapy Versus a Triple Combination Therapy Containing Darunavir/Ritonavir and 2 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors in Patients With Undetectable Plasma HIV-1 RNA on Current Treatment (PROTEA)

Human Immunodeficiency Virus (HIV) Infections | Acquired Immunodeficiency Syndrome (AIDS) Virus

France, United Kingdom, Belgium, Germany, Spain, Switzerland, Denmark, Israel, Austria, Poland, Hungary, Sweden, Ireland
Hennepin Healthcare Research Institute
American Heart Association

Completed

Cardiovascular Prevention for Persons With HIV

HIV Infection | Cardiovascular Disease Risk

United States
Indonesia University

Completed

The Effect of Zinc, β-carotene, and Vitamin D3 in Preterm Delivery Through Placental MyD88, TRIF, NFkB, and IL-1β

PreTerm Birth
AbbVie

Completed

Safety, Tolerability and PK Study of Single Doses of ABT-450 With and Without Ritonavir to Treat Hepatitis C Virus (HCV) Genotype 1

HCV Infection

United States

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