Search clinical trials for: LDL cholesterol treatment

Total 66898 results

University of Kansas Medical Center
Eli Lilly and Company; Kowa Pharmaceuticals America, Inc.

Completed

A Study Comparing CoQ10 Levels While Taking 3 Different Statins (SPARQ)

Hypercholesterolemia

United States
National Institute on Aging (NIA)

Completed

The Effects of Metformin on Blood Vessel Structure and Function

Hyperglycemia | Hypertension | Obesity | Hypercholesterolemia

United States
Leiden University Medical Center
Netherlands Heart Foundation

Completed

Rosuvastatin Use to Improve the Coagulation Profile in Patients With Venous Thrombosis (START)

Deep Vein Thrombosis | Pulmonary Embolism

Netherlands
Hospital Universitari Vall d'Hebron Research Institute

Completed

Stroke Treatment With Acute Reperfusion and Simvastatin

Stroke, Acute

Spain
UCSF Benioff Children's Hospital Oakland
University of California, Los Angeles

Completed

Effect of Simvastatin Treatment on Vaso-occlusive Pain in Sickle Cell Disease

Sickle Cell Disease

United States
Danone Research

Completed

Effect of the Consumption of a Fermented Milk Enriched With Plant Sterols (France)

Mildly Hypercholesterolemic Subjects

France
Unity Health Toronto

Unknown

Effect of Viscous Soluble Fibers on Serum Cholesterol Levels (CHOL-META)

LDL Cholesterol

Canada
Danone Japan

Completed

"A Clinical Study for Evaluating the Effect of a Plant Sterol-enriched Fermented Dairy Product on Blood Lipoprotein Profile in Japanese Adults"

Subjects With High LDL-Cholesterol

Japan
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Measure Liver Fat Content After ISIS 301012 (Mipomersen) Administration

Metabolic Diseases | Congenital Abnormalities | Infant, Newborn, Diseases | Genetic Diseases, Inborn | Dyslipidemias | Metabolism, Inborn Errors | Lipid Metabolism Disorders | Hypercholesterolemia | Hyperlipidemias | Lipid Metabolism, Inborn Errors | Hypobetalipoproteinemias | Hypolipoproteinemias | Hypolipopro... and other conditions

Netherlands
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Study to Assess the Safety and Efficacy of ISIS 301012 (Mipomersen) in Homozygous Familial Hypercholesterolemia (RADICHOL 1)

Metabolic Diseases | Congenital Abnormalities | Infant, Newborn, Diseases | Genetic Diseases, Inborn | Dyslipidemias | Metabolism, Inborn Errors | Lipid Metabolism Disorders | Hypercholesterolemia | Hyperlipidemias | Hyperlipoproteinemias | Lipid Metabolism, Inborn Errors | Hyperlipoproteinemia Type II | Metabolic... and other conditions

United States, Taiwan, Brazil, Canada, South Africa, United Kingdom, Singapore
Poznan University of Medical Sciences
University of California, San Diego

Unknown

Effects of Simvastatin and Micronized Trans-resveratrol Treatment on Polycystic Ovary Syndrome (PCOS) Patients

PCOS, Insulin Resistance

Poland
Arisaph Pharmaceuticals Inc

Unknown

Evaluation of ARI-3037MO, to Suppress LDL Cholesterol in Patients With Dyslipidemia (REASCEND)

Hyperlipidemia

United States
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Dose-escalating Safety Study of ISIS 301012 in Homozygous Familial Hypercholesterolemia Subjects on Lipid Lowering Therapy

Hypercholesterolemia, Familial

United States, Netherlands
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Study to Assess the Effects of Mipomersen on Lipid and Lipoprotein Metabolism in Healthy Subjects

Healthy Volunteer

United States
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Study of ISIS 301012 (Mipomersen) in Heterozygous Familial Hypercholesterolemia Subjects on Lipid Lowering Therapy

Hypercholesterolemia, Familial

United States, Netherlands
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

A Study to Determine the Effects of Multiple Doses of Mipomersen (200 mg SC) on the Pharmacodynamics and Pharmacokinetics of Single-dose Warfarin

Healthy

United States
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

A Study to Evaluate 3 Different Dosing Regimens of Mipomersen Administered Via Subcutaneous Injections to Healthy Volunteers

Healthy Volunteer

Canada
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Safety and Tolerability of Varying Load and Dose of ISIS 301012 in People With Elevated LDL-cholesterol Levels

Hypercholesterolemia

Germany
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Effect of Mipomersen on Cardiac Repolarization Conducted in Healthy Subjects

Healthy

United States
Kastle Therapeutics, LLC
Ionis Pharmaceuticals, Inc.

Completed

Dose-escalating Safety Study in Subjects on Stable Statin Therapy

Hypercholesterolemia

Netherlands, United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)

Myocardial Infarction | Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Heart Failure | Coronary Disease | Hypertension | Diabetes Mellitus | Hypercholesterolemia
Yonsei University

Completed

COmparison and Modification in Neointimal Pattern Assessed by Optical Coherence Tomography With High Versus Moderate Efficacy Statin Treatment After Drug Eluting Stent Implantation: COMPASS Trial

Coronary Artery Disease

Korea, Republic of
Yonsei University

Completed

Neointimal Coverage After Implantation of Biolimus Eluting Stent With Biodegradable Polymer: Optical Coherence Tomographic Assessment According to the Treatment of Dyslipidemia and Hypertension and the Types of Implanted Drug-eluting Stents

Stable Angina or Acute Coronary Syndrome Considered for Percutaneous Coronary Intervention With Dyslipidemia or Hypertension

Korea, Republic of
Marmara University

Completed

Is There a Relationship Between Hyperlipidemia and Periodontitis?

Hyperlipidemia, Periodontal Disease
AstraZeneca

Completed

A Study to Evaluate the Efficacy and Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hypercholesterolemia (HYDRA)

Homozygous Familial Hypercholesterolemia (HoFH)

Malaysia, Canada, Israel, Netherlands, Taiwan, Belgium, Denmark
Government Dental College and Research Institute...

Completed

Locally Delivered Atorvastatin & Rosuvastatin for Treatment of Furcation Defects in Chronic Periodontitis

Chronic Periodontitis

India
Yonsei University

Completed

The Effectiveness of Plant Stanols as Ester on Change in Blood Cholesterol Level

LDL-cholesterol Level 130-159mg/dL
John Sievenpiper
Canadian Institutes of Health Research (CIHR); Canadian Diabetes Association; The Physicians' Services Incorporated Foundation and other collaborators

Unknown

Meta-analyses of the Effect of Liquid Meal Replacements on Cardiometabolic Risk

Obesity | Overweight | Type 2 Diabetes

Canada
University of Manitoba
Canola Council of Canada; Alberta Innovates Bio Solutions; Alberta Canola Producers...

Completed

Effects of Canola Oil on Vascular and Metabolic Parameters in Individuals With Metabolic Syndrome (METCO-2013)

Metabolic Syndrome

Canada
Translational Research Center for Medical Innovation...
National Cerebral and Cardiovascular Center; Ministry of Health, Labour and... and other collaborators

Completed

Carotid Intima-media Thickness in Japan Statin Treatment Against Recurrent Stroke(J-STARS Echo)

Ischemic Stroke

Japan
Translational Research Center for Medical Innovation...
Osaka University; Ministry of Health, Labour and Welfare, Japan; Hiroshima University

Completed

hsCRP in Japan Statin Treatment Against Recurrent Stroke (J-STARS hsCRP)

Ischemic Stroke

Japan
International Maternal Pediatric Adolescent AIDS...
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy...

Terminated

IMPAACT P1063: Safety and Effectiveness of Atorvastatin in HIV Infected Children and Adolescents With Hyperlipidemia

HIV Infections | Hyperlipidemia

United States
Queen's University

Completed

Atorvastatin Versus Ezetimibe and Fenofibrate as a Lipid-lowering Strategy

Dyslipidemia | Vascular Disease

Canada
Pfizer

Completed

Single Dose Manufacturing Site (Pfizer vs. BIP) And Device (Prefilled Syringe vs. Prefilled Pen) Comparability Study For Bococizumab In Healthy Volunteers

Healthy

United States
University of Pennsylvania
Abbott

Completed

Combined Effects of Non-statin Treatments on Apolipoprotein A-I Up-Regulation (CENTAUR): A Feasibility Study (CENTAUR)

Dyslipidemia

United States
AstraZeneca

Completed

Observational Prospective Study OPTIMA II - Follow-up (OPTIMAII)

Major Adverse Cardiovascular and Cerebrovascular Events (MACCE)

Russian Federation
University of Washington
National Heart, Lung, and Blood Institute (NHLBI)

Completed

HDL-Atherosclerosis Treatment Study (HATS)

Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Coronary Disease
Xin Gao
Pfizer

Unknown

Atorvastatin Versus Vitamin E in Treatment of Non-alcoholic Fatty Liver Disease

Diabetes Mellitus | Fatty Liver | Dyslipidemias

China
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Withdrawn

Effect of HAART Vs. Statin Treatment on Endothelial Function and Inflammation/Coagulation

HIV-1 Infection

United States
Government Dental College and Research Institute...

Completed

Platelet-rich Fibrin With 1.2% Rosuvastatin in Chronic Periodontitis Treatment

Chronic Periodontitis

India
RenJi Hospital

Unknown

Exploratory Study on the Effects of Early Rosuvastatin Treatment in Patients With Acute Ischemic Stroke (AIS)

Ischemic
Amgen

Completed

Study of Low-Density Lipoprotein Cholesterol (LDL-C) Reduction Using Evolocumab (AMG 145) in Japanese Patients With Advanced Cardiovascular Risk (AMG145)

Hyperlipidemia or Mixed Dyslipidemia at High Risk for Cardiovascular Events

Japan
Alnylam Pharmaceuticals
The Medicines Company

Completed

A Phase 1 Study of an Investigational Drug, ALN-PCSSC, in Subjects With Elevated Low Density Lipoprotein Cholesterol (LDL-C)

Hypercholesterolemia

United Kingdom
Shenyang Northern Hospital

Completed

Study of Policosanol to Improve Platelet Reactivity After Percutaneous Coronary Stent Implantation (PCI) (spirit)

Coronary Artery Disease

China
Nordic Pharma, USA
Nutrasource Pharmaceutical and Nutraceutical Services, Inc.

Withdrawn

Efficacy Study of Daily Pro-Omega LDL for Low-Density Lipoprotein Cholesterol and Triglyceride Reduction (PrOteCT)

Mixed Hyperlipoproteinemia
Nordic Pharma, USA
Nutrasource Pharmaceutical and Nutraceutical Services, Inc.

Completed

Safety and Efficacy of a Natural Health Product in Reducing Cholesterol and Triglyceride Levels.

Triglycerides | LDL Cholesterol

Canada
University of Washington
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Familial Atherosclerosis Treatment Study (FATS)

Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Coronary Disease | Coronary Arteriosclerosis
Nazarbayev University
Institute Of Cardiology & Internal Diseases, Kazakhstan

Completed

Development of Rational Ways of Medical and Non-medical Treatment Methods for Metabolic Syndrome (DRWMNTMS)

Metabolic Syndrome

Kazakhstan
HealthPartners Institute

Completed

Assessment of Non-Fasting vs. Fasting Lipid Measures in Diabetes Patients

Diabetes Mellitus | Hyperlipidemia | Normal Glucose Metabolism

United States
Government Dental College and Research Institute...

Completed

Platelet Rich Fibrin+1.2% Atorvastatin in Treatment of Mandibular Degree II Furcation Defects

Furcation Defects

India

Search clinical trials for: LDL cholesterol treatment

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