Search clinical trials for: Malignant Transformation

Total 5761 results

Cancer Research UK
Royal Marsden NHS Foundation Trust; Hoffmann-La Roche; University of Manchester; University of Birmingham

Recruiting

DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial) - Master Screening Protocol (DETERMINE)

Solid Tumor | Haematological Malignancy

United Kingdom
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Time-Restricted Eating Versus Nutritional Counseling for the Reduction of Radiation or Chemoradiation Tx Side Effects in Patients With Prostate, Cervical, or Rectal Cancers

Malignant Solid Neoplasm | Recurrent Prostate Carcinoma | Localized Prostate Carcinoma | Stage I Prostate Cancer AJCC v8 | Stage II Prostate Cancer AJCC v8 | Stage IIA Cervical Cancer FIGO 2018 | Stage IIB Cervical Cancer FIGO 2018 | Stage IIIA Cervical Cancer FIGO 2018 | Stage IIIB Cervical Cancer... and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Not yet recruiting

Pharmacodynamic Analyses of Metabolic Agents Following Brain Radiation

Malignant Central Nervous System Neoplasm

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Intratumoral Extracellular Metabolic Impact of DFMO and AMXT 1501 in Patients With Diffuse or High Grade Glioma

Malignant Glioma | Diffuse Glioma

United States
Mayo Clinic

Not yet recruiting

Aerosolized Sargramostim Added to Immunotherapy for the Treatment of Patients With Metastatic Melanoma to the Lung

Metastatic Melanoma | Recurrent Melanoma | Unresectable Melanoma | Clinical Stage IV Cutaneous Melanoma AJCC v8 | Metastatic Malignant Neoplasm in the Lung

United States
National Cancer Institute (NCI)

Recruiting

Testing the Combination of Anti-cancer Drugs Atezolizumab and Tiragolumab in People With Advanced Stage Rare Cancers, RARE3 Trial

Advanced Rare Malignant Solid Neoplasm | Rare Malignant Solid Neoplasm | Refractory Rare Malignant Solid Neoplasm

United States
West China Hospital

Recruiting

Application of mRNA Immunotherapy Technology in Epstein-Barr Virus-related Refractory Malignant Tumors

Malignant Tumors

China
NuCana plc

Recruiting

NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours

Melanoma | Renal Cell Carcinoma | Gastric Cancer | Non Small Cell Lung Cancer | Metastatic Cancer | Triple Negative Breast Cancer | Advanced Solid Tumor | Advanced Cancer | Head and Neck Squamous Cell Carcinoma | Endometrial Carcinoma | Urothelial Carcinoma | Classical Hodgkin Lymphoma | Neoplasm Malignant | Pleural... and other conditions

United Kingdom
Children's Oncology Group

Recruiting

A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm

United States
University Hospital, Basel, Switzerland

Recruiting

Effect of Glyceroltrinitrate on Human Energy Expenditure and Brown Adipose Tissue Thermogenesis (NEXT)

Brown Adipose Tissue

Switzerland
West China Hospital

Recruiting

Clinical Study of Therapeutic Immunological Agent for EBV-positive Advanced Malignant Tumors

Malignant Tumor

China
M.D. Anderson Cancer Center

Recruiting

Study of CAR.70-engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Renal Cell Carcinoma, Mesothelioma and Osteosarcoma

Advanced Renal Cell Carcinoma | Advanced Mesothelioma | Advanced Osteosarcoma

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI); Oregon Health and Science University

Recruiting

Olanzapine for the Management of Cancer Associated Appetite Loss in Patients With Advanced and Incurable Solid Tumors

Advanced Malignant Solid Neoplasm

United States
Children's National Research Institute

Recruiting

International Rare Brain Tumor Registry (IRBTR)

Astroblastoma | BCOR ITD Sarcoma | CNS Sarcoma | Unclassified Tumor, Malignant

United States
Mabpro, a.s.

Not yet recruiting

Clinical Study to Evaluate Safety and Dosing of CA9hu-1 in Patients With Advanced Solid Tumours (CAMP1)

Head and Neck Cancer | Mesothelioma, Malignant | TNBC - Triple-Negative Breast Cancer | Non-small-cell Lung Carcinoma | Clear Cell Renal Cell Carcinoma Metastatic
Duke University
Personalis Inc.

Recruiting

GRETeL: Tumor Response to Standard Radiotherapy and TMZ Patients With GBM

Glioblastoma | Glioma, Malignant

United States
Assiut University

Not yet recruiting

Cancer Ratio,Pleural Fluid Adenosine Deaminase,Lactate Dehydrogenase, interferonY, Tumor Necrosis Factor,and Interleukins{2,12,18}for Differentiation Between Malignant and Non Malignant Pleural Effusion

Pleural Effusion, Malignant
National Cancer Institute (NCI)

Recruiting

Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Stage IV Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Metastatic Microsatellite Stable Colorectal Carcinoma | Advanced Microsatellite Stable Colorectal Carcinoma | Hematopoietic and Lymphatic System...

United States
Assiut University

Not yet recruiting

The Value of Ultrasound Elastography for Differentiating Benign and Malignant Superficial Soft Tissue Masses

Ultrasound Therapy; Complications
University of British Columbia

Recruiting

Polyomic Biomarker Verification in Adult Chronic Graft-Versus-Host Disease (ABLE3.0/CTTC2201)

Leukemia | Allogeneic Hematopoietic Stem Cell Transplantation | Blood Cancer | Chronic Graft-versus-Host-Disease | Non-Malignant Hematologic and Lymphocytic Disorder

United States, Canada
National Cancer Institute (NCI)

Recruiting

Testing How the Body Responds to the Drug CBX-12 in Patients With Advanced Solid Cancers

Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
National Cancer Institute (NCI)

Recruiting

Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes

Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
National Cancer Institute (NCI)

Recruiting

Testing the Combination of Two Anti-cancer Drugs, Peposertib (M3814) and M1774 for Advanced Solid Tumors

Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
National Cancer Institute (NCI)

Recruiting

Defining the Natural History of Squamous Cell Carcinoma in Fanconi Anemia

Fanconi Anemia | Inherited Bone Marrow Failure Syndrome

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Evaluation of the Quality of Life Induced by the Cinnamon Anti-odor Dressing in Patients With Malodorous Wounds (CINNAMON)

Malodorous Wounds (Chronic, Malignant or Infected Wounds)

France
Henry Ford Health System

Recruiting

Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.

Glioma | Glioblastoma | Astrocytoma | Malignant Glioma of Brain | Brain Cancer | Brain Tumor | Glioblastoma Multiforme | GBM | Malignant Astrocytoma

United States
Johns Hopkins University

Recruiting

Multi-parametric Biomarker Development to Predict Malignant Conversion in Patients With Neurofibromatosis Type 1

Neurofibromatosis 1 | Atypical Neurofibroma | Malignant Peripheral Nerve Sheath Tumor (MPNST) of Soft Tissue (Diagnosis)

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Lisocabtagene Maraleucel, Nivolumab and Ibrutinib for the Treatment of Richter's Transformation

Richter Syndrome | Recurrent Transformed Chronic Lymphocytic Leukemia | Refractory Transformed Chronic Lymphocytic Leukemia

United States
Beijing Tiantan Hospital

Recruiting

Genetic and Molecular Risk Profiles of Pediatric Malignant Brain Tumors in China (GRIPP)

Glioma | Ependymoma | Medulloblastoma | Central Nervous System Tumor, Pediatric | Germ Cell Tumor | Brain Tumor, Pediatric

China
Beijing Tiantan Hospital

Not yet recruiting

Cerebral Autoregulation Guiding Blood Pressure Management After Revascularization (RESCUE-CA)

Ischemic Stroke | Blood Pressure | Cerebral Autoregulation | Revascularization | Cerebrovascular Insufficiency | Individuation | Hemorrhagic Transformation Due to Acute Stroke
GCS Ramsay Santé pour l'Enseignement et la Recherche

Not yet recruiting

Evaluation of the Contribution of NODDI Protocol Tractography in Brain Tumor Surgery (NODDI-TRACT)

Malignant Brain Tumor

France
Verastem, Inc.

Recruiting

Study of Avutometinib (VS-6766) +Defactinib With Gemcitabine and Nab-paclitaxel in Patients With Pancreatic Cancer (RAMP205)

Metastatic Cancer | Pancreas Cancer | Neoplasms Pancreatic | KRAS Activating Mutation | Malignant Neoplasm of Pancreas

United States
Letolab

Not yet recruiting

Study of LTC004 in Subjects With Advanced Malignant Tumors

Adult Solid Tumor
Instituto Brasileiro de Controle do Cancer

Recruiting

Efficacy and Safety of Ultra_HYPofractionated RadiotHerapy in Women With BrEast CaNcer Receiving Regional Nodal Radiation vs Nodal Moderate Hypofractionated Radiotherapy (HYPHEN)

Malignant Breast Neoplasm

Brazil
Fujian Cancer Hospital
Jiangsu Hengrui Pharmaceutical Co., Ltd.; SunWay Biotech Co., LTD.

Not yet recruiting

Recombinant Human Adenovirus Type 5 Injection Combined With PD-1 Monoclonal Antibody and Nab-paclitaxel in the Treatment of Patients With Liver Metastases From Malignant Melanoma

Liver Metastases | Malignant Melanoma
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Recruiting

Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers

HIV Infection | Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Lymphoma | Multicentric Castleman Disease | Plasmablastic Lymphoma | Kaposi Sarcoma | Recurrent Lymphoma | Anal Carcinoma | Recurrent Kaposi Sarcoma | Recurrent Plasmablastic Lymphoma | Transplant-Related Kaposi Sarcoma

United States
Ain Shams University

Recruiting

Switch-Maintenance Gemcitabine After First-Line Chemotherapy In Patients With Malignant Pleural Mesothelioma

Malignant Pleural Mesothelioma

Egypt
Marcela V. Maus, M.D.,Ph.D.

Recruiting

CARv3-TEAM-E T Cells in Glioblastoma

Glioblastoma | Malignant Glioma | Recurrent Glioblastoma | Recurrent Glioma

United States
Douglas Johnson
Incyte Corporation

Recruiting

Itacitinib for the Treatment Steroid Refractory Immune Related Adverse Events Arising From Immune Checkpoint Inhibitors

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm

United States
University College, London
University of Sheffield; Asthma + Lung UK; Mesothelioma UK

Recruiting

Hemithoracic Irradiation With Proton Therapy in Malignant Pleural Mesothelioma (HIT-Meso)

Malignant Pleural Mesothelioma

United Kingdom
Assistance Publique - Hôpitaux de Paris
VR 4 GOOD

Recruiting

Use of VIrtual REAlity to Reduce Postoperative Anxiety and Pain After Surgery for Colorectal Cancer (VIREA)

Pain, Postoperative | Colon Tumor, Malignant | Rectum Tumor

France
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Nab-Paclitaxel/STI-3031 Complex (AP160-Complex) for the Treatment of Advanced or Metastatic Solid Tumors

Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Unresectable Melanoma

United States
Akeso

Not yet recruiting

A Study of AK130 in Patients With Advanced Malignant Tumors

Advanced Malignant Tumors
Tasly Biopharmaceuticals Co., Ltd.

Not yet recruiting

A Study of B1962, a PD-L1/VEGF Bispecific Antibody Fusion Protein, for Advanced Solid Tumors

Neoplasms Malignant

China
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Immunotherapy Before Surgery for Patients With Sarcomatoid Mesothelioma

Pleural Biphasic Mesothelioma | Pleural Sarcomatoid Mesothelioma

United States
Russian Society of Colorectal Surgeons

Recruiting

Self-expandable Metal Stent (SEMS) Endoscopic Placement for Malignant Colonic Obstruction Therapy (PATENCY)

Neoplasms,Colorectal

Russian Federation
Akeso

Recruiting

A Study of AK129 in Patients With Advanced Malignant Tumors

Advanced Malignant Tumors(Stage IA-IB)

China
The Affiliated Hospital of Xuzhou Medical University

Not yet recruiting

Study on the Treatment of Advanced Malignant Solid Tumor With Revottack and PD-1 Inhibitor

Advanced Solid Tumor

China
Chengjun Sui,MD

Not yet recruiting

Clinical Transformation of Organoid Model to Predict the Efficacy of GC in the Treatment of Intrahepatic Cholangiocarcinoma

Intrahepatic Cholangiocarcinoma | Organoids
Wuhan Union Hospital, China

Recruiting

The Prognostic Value of 18F-PFPN PET Imaging in Patients With Malignant Melanoma

Melanoma

China

Search clinical trials for: Malignant Transformation

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