Search clinical trials for: Second line therapy

Total 70743 results

Peking Union Medical College Hospital

Recruiting

Efficacy of Thyroid Hormone Replacement for Secondary Hypothyroidism Following Intracerebral Hemorrhage

Hormone Replacement Therapy | Intracerebral Hemorrhage | Low T3 Syndrome | Neurocritical Care

China
Mayo Clinic
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Recruiting

Biomarkers to Predict Cancer Therapy-related Cardiotoxicity

Malignant Solid Neoplasm | Hematopoietic and Lymphatic System Neoplasm

United States
Qilu Hospital of Shandong University

Not yet recruiting

Efficacy and Safety of Bismuth Quadruple Therapy Containing Cefuroxime and Tetracycline as First-line Therapy for Eradicating Helicobacter Pylori in Patients Allergic to Penicillin

Helicobacter Pylori Infection

China
West China Hospital

Not yet recruiting

Nab-paclitaxel Combined With Cadonilimab (AK104) for the Second-line Treatment of Advanced Gastric Cancer

Gastric Cancer
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Cytoreductive Prostatectomy Combined With Triple or Dual Systemic Therapy in mHSPC Patients

Metastatic Prostate Cancer | Therapy, Directly Observed

China
West Virginia University

Not yet recruiting

Emergency Department Management of Tobacco Use Disorder

Tobacco Use Disorder | Tobacco Use Cessation

United States
Zhejiang Cancer Hospital

Recruiting

A Randomized, Multicenter Phase II Basket Study of Hypofractionated Radiotherapy/Stereotactic Body Radiotherapy Followed by Immunotherapy-Based Systemic Therapy +/- L. Rhamnosus M9 for the First-Line Treatment of Advanced Digestive System Malignancies.

Gastric Cancer | Colorectal Cancer | Pancreatic Adenocarcinoma | Biliary Tract Cancer | Gastroesophageal Junction Adenocarcinoma | Liver Cancer Stage IV

China
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Study of the Food Effects of Herombopag Olamine Tablets in Healthy Subjects.

Adult Patients With Chronic Primary ITP | Adult Patients With SAA Who do Not Respond Well to Immunosuppressive Therapy

China
UNC Lineberger Comprehensive Cancer Center
Bellicum Pharmaceuticals

Not yet recruiting

Study of Autologous CAR-T Cells Targeting B7-H3 in TNBC iC9-CAR.B7-H3 T Cells

Breast Cancer | Triple Negative Breast Cancer | Relapse | Resistant Cancer

United States
Second Affiliated Hospital of Soochow University

Not yet recruiting

PRaG Therapy in Combination With Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC) (NeoPRAG Study)

Pancreatic Ductal Adenocarcinoma
Fudan University

Recruiting

Abemaciclib, Palbociclib or Dalpiciclib Combined With Endocrine Therapy as First-line Treatment in HR Positive, HER2 Negative Unresectable or Metastatic Breast Cancer

Breast Cancer

China
Bristol-Myers Squibb

Recruiting

Real-World Outcomes of Nivolumab+Ipilimumab and Pembrolizumab+Lenvatinib Among US Advanced Renal Cell Carcinoma (aRCC) Patients

Advanced Renal Cell Carcinoma (aRCC)

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
Yale University; AstraZeneca

Not yet recruiting

PRagmatic Study Of Messaging to Providers of Patients With Heart Failure in Amsterdam UMC (PROMPT-HF-AUMC)

Heart Failure With Reduced Ejection Fraction
Fondazione IRCCS Policlinico San Matteo di Pavia

Recruiting

Potential Protective Role of SGLT-2 Inhibitors for Chemotherapy-induced Cardiotoxicity (PROTECT)

Breast Cancer

Italy
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Combination Immunotherapy of Adebrelimab With Apatinib and Tegafur for Immune Rechallenge Therapy in Esophageal Squamous Cell Carcinoma

Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma

China
Chinese PLA General Hospital

Not yet recruiting

A Clinical Study of Adebrelimab Combined With Apatinib and Paclitaxel in Patients With Advanced Gastric Cancer.

Gastric Cancer
Fudan University

Recruiting

HAIC Combined With Cadonilimab and Regorafenib as 2nd-line Treatment for ICC

Intrahepatic Cholangiocarcinoma

China
Abramson Cancer Center at Penn Medicine

Not yet recruiting

Effects of Immune Checkpoint Inhibitors on Coronary Microvasculature

Melanoma | Cardiotoxicity | Coronary Microvascular Dysfunction

United States
Rui-hua Xu, MD, PhD

Not yet recruiting

A Phase II Study of Surufatinib Combined With Camrelizumab and mFOLFOX6 as Second-line Treatment for Advanced PRAD

Advanced Pancreatic Cancer

China
Hunan Cancer Hospital

Not yet recruiting

Cadonilimab in Combination With Anlotinib in the Treatment of Locally Progressive or Metastatic Melanoma With First-Line Therapy Failure

Melanoma
University Hospital of Ferrara

Recruiting

ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing (TREEBEARD)

Atrial Fibrillation | Arrhythmias, Cardiac | Left Bundle-Branch Block | Bundle-Branch Block | Ventricular Fibrillation | Ventricular Tachycardia | Ventricular Dysfunction | Atrioventricular Block | Heart Failure, Systolic | Ventricular Arrythmia | Heart Failure，Congestive | Bradyarrhythmia | Heart Arrhythmia | Reduced... and other conditions

Italy
Riphah International University

Recruiting

Muscle Energy Technique of Lower Limb Muscles in Forward Head Posture

Forward Head Posture

Pakistan
Nantes University Hospital

Recruiting

Prospective Multicenter Randomized and Controlled Study Evaluating the Benefit of Early Pulmonary Vein Isolation Compared to Usual Treatment in Patients Aged Over 75 Years and Presenting With Atrial Fibrillation (EDearly AF)

Atrial Fibrillation

France
Peking University First Hospital

Recruiting

Fruquintinib Plus Everolimus as 2nd Line Therapy of ccRCC Patients Progressed Post IO and TKI Therapy

Renal Cell Carcinoma, Clear Cell, Somatic

China
Feixue Song

Recruiting

Electroacupuncture Plus Antiemetic Therapy for Chemotherapy-Induced Nausea and Vomiting in Patients With Breast Cancer

Electroacupuncture | Nausea and Vomiting | Olanzapine-contained Four-drug Antiemetic

China
Washington University School of Medicine
The Foundation for Barnes-Jewish Hospital

Recruiting

Online Proton Adaptive Radiotherapy (PARTy)

Solid Tumor

United States
The University of Hong Kong-Shenzhen Hospital

Not yet recruiting

iTAPVR Study - Phase II Randomized Study

Advanced Tumors
Jian Chen

Recruiting

Carbon Ion Radiotherapy for Locally Advanced Lung Cancer in Elderly Patients

Older People | Non-small Cell Lung Cancer | Radiotherapy Side Effect | Carbon Ion Radiotherapy

China
Fundación Oftalmológica de Santander Clínica Carlos...
Instituto Distrital de Ciencia, Biotecnología e Innovación en Salud - IDCBIS

Not yet recruiting

Sequential Administration of WJ-MSCs for the Treatment of GvHD Refractory to Second Line Treatment (GvHD)

Graft Versus Host Disease
UNC Lineberger Comprehensive Cancer Center

Not yet recruiting

Autologous CAR-T Cells Targeting B7H3 in Ovarian Cancer iC9-CAR.B7-H3 T Cells

Ovarian Cancer | Epithelial Ovarian Cancer | Ovary Neoplasm | Recurrent

United States
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

D-1553 Tablet Versus Docetaxel Injection for KRAS G12C Mutation-positive Locally Advanced or Metastatic Non-small Cell Lung Cancer After Prior Standard Therapy Failure

Non Small Cell Lung Cancer

China
Tor Biering-Sørensen

Not yet recruiting

Nationwide Utilization of Danish Government Electronic Letter System for Increasing Guideline-directed Medical Therapy in Chronic Kidney Disease (NUDGE-CKD)

Chronic Kidney Diseases | Behavior and Behavior Mechanisms

Denmark
Servier Affaires Médicales

Recruiting

Effectiveness of a Combination of Trimetazidine With One Hemodynamic Agent in Patients Recently Diagnosed With Stable Angina and Still Symptomatic Despite First Line Hemodynamic Therapy

Stable Angina

Romania
Karolinska Institutet
Karolinska University Hospital

Recruiting

Internet-based Behavioral Intervention Following ACS (ACS-CBT)

Acute Coronary Syndrome | Online CBT Targeting Cardiac Anxiety

Sweden
Zeng Changhao

Not yet recruiting

Intermittent Oro-esophageal Tube on Rehabilitation Therapy Compliance in Stroke Patients

Stroke

China
Juno Therapeutics, Inc., a Bristol-Myers Squibb...

Recruiting

Study of BMS-986393 a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma (QUINTESSENTIAL)

Multiple Myeloma

United States, Canada
Henan Cancer Hospital

Recruiting

TAS-102 Combined With Bevacizumab for Second-line Maintenance Treatment of Advanced Colorectal Cancer

Colorectal Cancer

China
Second Affiliated Hospital of Soochow University

Not yet recruiting

Plasma cfDNA Testing Guiding the Treatment Decisions of DLBCL

Lymphoma, Large B-Cell, Diffuse

China
University of Virginia
American Heart Association

Recruiting

Implementation of Onsite Rapid CYP2C19 Assay for Genotype Guided Dual Antiplatelet Therapy After Acute Ischemic Stroke (ORCA-AIS)

Ischemic Stroke | CYP2C19 Polymorphism

United States
Tongji Hospital
Zhejiang Cancer Hospital; Xiangya Hospital of Central South University; Beijing... and other collaborators

Not yet recruiting

Neoadjuvant Chemoimmunotherapy Versus Concurrent Chemoradiotherapy for LACC

Cervical Cancer | Locally Advanced Cervical Cancer | Concurrent Chemoradiotherapy | Neoadjuvant Chemoimmunotherapy

China
University of Patras

Recruiting

Rehabilitation of Abdominal Diastasis After Childbirth: Trunk and Inspiratory Muscle Training (DR-TIME)

Diastasis, Muscle | Diastasis Recti And Weakness Of The Linea Alba

Greece
Milton S. Hershey Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Cognitive Behavioral Therapy and Trazodone Effects on Sleep and Blood Pressure in Insomnia

Insomnia | Blood Pressure | Insomnia Chronic | Insomnia, Primary | Blood Pressure, High

United States, Canada
Chengdu New Radiomedicine Technology Co. LTD.

Not yet recruiting

Safety and Efficacy of NRT6008 in Patients With Unresectable Locally Advanced Pancreatic Cancer (LAPC)

Unresectable Pancreatic Cancer

China
Universitat Jaume I

Recruiting

Physical Exercise Benefits for Cancer Patients

Sports Physical Therapy | Cancer, Breast

Spain
Inova Fairfax Hospital
Eastern Virginia Medical School

Recruiting

Erythromycin Versus Azithromycin for Preterm Prelabor Rupture of Membranes (PRACET)

Premature Rupture of Membrane

United States
Alnylam Pharmaceuticals

Recruiting

Zilebesiran as Add-on Therapy in Patients With High Cardiovascular Risk and Hypertension Not Adequately Controlled by Standard of Care Antihypertensive Medications (KARDIA-3) (KARDIA-3)

Hypertension | High Cardiovascular Risk

United States, Canada, Switzerland, United Kingdom
Poznan University of Medical Sciences
MagForce USA

Recruiting

NanoTherm In Adjuvant Therapy of Glioblastoma Multiforme (ANCHIALE)

Glioblastoma Multiforme

Poland
IRCCS San Raffaele

Recruiting

RRMS: Disease PROgression and Myeloid Profiling After Bone Marrow TRANSPLANTation and Second Line Therapies (TRANSPLANTPRO)

Multiple Sclerosis

Italy
Bristol-Myers Squibb

Recruiting

Study to Evaluate the Efficacy, Safety, and Tolerability of an Anti-MTBR Tau Monoclonal Antibody (BMS-986446) in Participants With Early Alzheimer's Disease (TargetTau-1)

Alzheimer Disease, Early Onset

United States, Australia, Belgium, Canada, France, Japan, Korea, Republic of, Netherlands, Singapore, Spain, Sweden, United Kingdom
King's College London

Not yet recruiting

Emotional Support for Women Experiencing PPROM

Fetal Membranes, Premature Rupture | Preterm Birth Complication

United Kingdom

Search clinical trials for: Second line therapy

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