Search clinical trials for: Switch

Total 1023 results

Pfizer
Hospira, now a wholly owned subsidiary of Pfizer

Completed

Post-Marketing Use Of CT-P13 (Infliximab) For Standard Of Care Treatment Of Rheumatoid Diseases Who Are Naïve To Biologics Or Switched From Remicade (PERSIST)

Rheumatoid Arthritis | Psoriatic Arthritis | Ankylosing Spondylitis | Rheumatoid Diseases

Spain, Canada, Greece, United Kingdom, Germany, Bulgaria, Czechia
Kasr El Aini Hospital

Completed

Treatment of Melasma Using Q-switched Nd: YAG Laser and Fractional CO2 Laser Separately and in Combination

Melasma

Egypt
Aziende Chimiche Riunite Angelini Francesco S.p.A
Mediolanum Cardio Research

Terminated

SALT Study (Switching to the Administration of Lithium Slow -Release Treatment)

Bipolar Disorder

Italy
Gilead Sciences

Completed

Study to Evaluate Switching From a Regimen Consisting of Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate (EFV/FTC/TDF) Fixed Dose Combination (FDC) to Emtricitabine/Rilpivirine/Tenofovir Alafenamide (FTC/RPV/TAF) FDC in Virologically-Suppressed, HIV-1 Infected Adults

HIV-1 Infection

Spain, United States, United Kingdom, Switzerland, Germany, Canada, France, Belgium, Puerto Rico
Gilead Sciences

Completed

Switch Study to Evaluate the Safety and Efficacy of Emtricitabine/Rilpivirine/Tenofovir Alafenamide (FTC/RPV/TAF) Fixed Dose Combination (FDC) in HIV-1 Positive Adults Who Are Virologically Suppressed on Emtricitabine/Rilpivirine/Tenofovir Disoproxil Fumarate (FTC/RPV/TDF)

HIV-1 Infection

United States, Spain, United Kingdom, Netherlands, Germany, Canada, Sweden, Switzerland, Italy, Belgium, Puerto Rico, France
Rabin Medical Center
Juvenile Diabetes Research Foundation; University of Padova; Jaeb Center for... and other collaborators

Completed

Personalized Automated Determination of Insulin Pump Setting for Subjects With Type 1 Diabetes Switching From MDI to Pump Therapy and Vice Versa- Safety and Efficacy Feasibility Study

Type1diabetes

Israel
Saskatchewan Health Authority - Regina Area
Gilead Sciences

Unknown

Switch to Genvoya Followed by HCV Therapy With Epclusa Followed by Simplification of HIV Therapy With Biktarvy in Patients With HIV-HCV Co-Infected Subjects on Opioid Substitution Therapy

Hepatitis C, Chronic | HIV/AIDS | Bone Diseases, Metabolic | Opioid Dependence | HIV-1-infection | HCV Coinfection | Buprenorphine Dependence | Methadone Dependence | Co-infection

Canada
IlDong Pharmaceutical Co Ltd

Unknown

Switching From Tenofovir Disoproxil Fumarate to Besifovir Dipivoxil Maleate

Hepatitis B | Besifovir Dipivoxil Maleate | Tenofovir Disoproxil Fumarate

Korea, Republic of
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Hydroxyurea for the Treatment of Patients With Sickle Cell Anemia

Sickle Cell Anemia

United States
Novartis Pharmaceuticals

Terminated

Trial to Evaluate the Improvement of Chronic Low-grade AEs in Patients With Ph+ CML With Optimal Response to Imatinib When Switched to Nilotinib (MACS1532)

Philadelphia Positive (Ph+) Chronic Myeloid Leukemia

Russian Federation
Novo Nordisk A/S

Completed

A Canadian Study of the Effectiveness of Tresiba® (Insulin Degludec) After Switching Basal Insulin in a Population With Type 1 or Type 2 Diabetes Mellitus (CAN-TREAT)

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1

Canada
University of Mogi das Cruzes

Completed

System for Quantifying the Functional Strength of the Grip and Pinch Movements

Hand Injuries and Disorders

Brazil
Philip Morris Products S.A.

Completed

Investigate the Exposure to Selected Smoke Constituents in Smokers Switching to Distillation Based Smoking Article

Smoking

Poland
Medical Centre Leeuwarden

Withdrawn

Effect of Atrial Pacing on Right Ventricular Function After Cardiac Surgery (Outpace)

Right Ventricular Ejection Fraction
University of Minnesota

Completed

Location of GLP-1 Release

Obesity

United States
Gilead Sciences

Completed

Switch Study to Evaluate F/TAF in HIV-1 Infected Adults Who Are Virologically Suppressed on Regimens Containing ABC/3TC

HIV-1 Infection

Spain, United Kingdom, Sweden, Germany, United States, France, Belgium, Ireland, Italy, Denmark, Puerto Rico, Canada
Vancouver Infectious Diseases Centre

Unknown

Switching to a Fixed Dose Combination of Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) in HIV-1 Infected Marginalized Populations Who Are Virologically Suppressed

Drug Use | Human Immunodeficiency Virus I Infection

Canada
Vanderbilt University Medical Center

Completed

Switching Medications From Intravenous to Oral

Administration, Oral | Physician's Role

United States
University Hospital, Grenoble
Hôpital Raymond Poincaré; Association Française contre les Myopathies (AFM)...

Completed

Impact of the Type of Interface in Neuromuscular Patients Treated With Nocturnal Noninvasive Ventilation (InterfaceNMD)

Neuromuscular Diseases | Alveolar Hypoventilation

France
Biogen
AbbVie

Terminated

Efficacy and Safety of Daclizumab in Participants With RRMS Switching From Natalizumab (SUSTAIN)

Relapsing-Remitting Multiple Sclerosis (RRMS)

Italy, United States, Canada, Germany, Puerto Rico
Seng Gee Lim
Merck Sharp & Dohme LLC; Singapore General Hospital; Tan Tock Seng Hospital; Changi... and other collaborators

Completed

Efficacy of Switching or Adding Pegylated Interferon in Chronic Hepatitis B Patients on Long Term Oral Antiviral Therapy (SWAP)

Chronic Hepatitis B

Singapore
Thomas Jefferson University

Completed

Assessing Virologic Success and Metabolic Changes in Patients Switching From a TDF to TAF Containing Antiretroviral Therapy Regimen

Hyperglycemia | Cardiovascular Diseases | Metabolic Syndrome | Weight Gain | HIV-1-infection | Renal Function Abnormal

United States
Novartis Pharmaceuticals

Completed

A Randomized, Multicenter, Open-label, Parallel-group, 12-week Study to Assess the Efficacy and Safety of Switching From Tiotropium to QVA149 (Indacaterol Maleate/Glycopyrronium Bromide) in Symptomatic Mild to Moderate COPD Patients

COPD

Korea, Republic of
University of Ulm
Sanofi; Assign Data Management and Biostatistics GmbH; Hubertus-Wald-Cancer Center...

Unknown

PERMAD: Personalized Marker-driven Early Switch to Aflibercept in Patients With Metastatic Colorectal Cancer (PERMAD)

Metastatic Colorectal Cancer

Germany
Medtronic Diabetes

Completed

SWITCH - Sensing With Insulin Pump Therapy to Control HbA1c (SWITCH)

Diabetes Mellitus, Type 1

Netherlands, Slovenia, Denmark, Austria, Italy, Luxembourg, Spain
Imperial College London
Mater Misericordiae University Hospital

Terminated

The St. Marys and The Mater Switch Study (SMASH)

HIV Infections

Ireland, United Kingdom
Calmy Alexandra

Completed

Evaluation of a Simplified Strategy for the Long-term Management of HIV Infection (Simpl'HIV) (Simpl'HIV)

Antiretroviral Therapy | HIV-1-infection | Maintenance Therapy

Switzerland
A.O. Ospedale Papa Giovanni XXIII
San Raffaele University Hospital, Italy

Unknown

RPV+DRV/Cobi Dual Therapy in Subjects With HIV Controlled Infection (PROBE2)

HIV Infection

Italy
GlaxoSmithKline

Completed

Omalizumab to Mepolizumab Switch Study in Severe Eosinophilic Asthma Patients

Asthma

United States, Argentina, France, Germany, Spain, Canada, Sweden, Netherlands, Belgium
Cristina Mussini

Unknown

Evaluating Inflammatory and Immunological Changes of HIV-positive Patients Switching to DTG Dual Regimen Compared to Those Switching to a Triple Drugs Regimen (B/F/TAF)

HIV Infections
Iowa State University
Kansas State University; Louisiana State University Health Sciences Center... and other collaborators

Completed

SWITCH Implementation Effectiveness Trial

Health Promotion | Overweight and Obesity | Sedentary Behavior | Diet, Healthy | Healthy Lifestyle

United States
University of California, San Diego

Withdrawn

Pilot Study of Continuing Aspirin Versus Switching to Clopidogrel After Stroke or Transient Ischemic Attack

Stroke | Transient Ischemic Attack | Aspirin | Clopidogrel

United States
AstraZeneca
Quintiles, Inc.

Completed

Immune-Modulated Study of Selected Small Molecules (Gefitinib, AZD9291, or Selumetinib + Docetaxel) or a 1st Immune-Mediated Therapy (IMT; Tremelimumab) With a Sequential Switch to a 2nd IMT (MEDI4736) in Patients With Locally Advanced or Metastatic Non-Small-Cell Lung Cancer

Locally Advanced or Metastatic Non-Small-Cell Lung Cancer (Stage IIIB-IV)

United States
Janssen-Cilag International NV

Completed

A Survey to Collect Treatment Experience Feedback From Patients, Physicians, Nurses and Carers After Switching to Paliperidone Palmitate 3-monthly

Schizophrenia

Germany, Spain, Belgium, Hungary, France, Italy, United Kingdom
The First Hospital of Jilin University

Unknown

A Perspective Study of the Antiviral Efficacy and Safety of Switching to TAF Treatment in CHB Adults With Suboptimal Response (SOR) and Intolerant to Entecavir

HBV
Chiang Mai University

Unknown

Neurocognitive Function Improvement After Switching From Efavirenz to Rilpivirine

HIV-1-infection | Neurocognitive Dysfunction

Thailand
Bernardete Pessoa MD

Completed

Intravitreal Ranibizumab or Aflibercept After Bevacizumab in Diabetic Macular Edema (SWITCH)

Diabetic Retinopathy | Diabetic Macular Edema
Nestlé

Completed

Retrospective Tube Feeding Tolerance in Adults With Intolerance After Switch to a Peptide-Based Formula (RAP)

Enteral Feeding Intolerance

Canada
University Hospital, Lille
Shire

Completed

IgG Level in Primary Immunodeficiency Switching From Standard SCIG to Every Other Week HyQvia

Primary Immunodeficiency

France
Sanofi

Terminated

Cabazitaxel Versus the Switch to Alternative AR Targeted Therapy Enzalutamide or Abiraterone in Metastatic Castration-Resistant Prostate Cancer (mCRPC) Primary Resistant Patients to Abiraterone or Enzalutamide (PRIMCAB)

Prostate Cancer Metastatic

Canada, United States
Fundación Pública Andaluza Progreso y Salud

Unknown

Antiplatelet Therapy in Acute Coronary Syndrome(ACS). Safety and Efficacy of Switching Antiplatelet

Acute Coronary Syndrome

Spain
University of Southern California

Completed

Switch to Ticagrelor in Critical Limb Ischemia Anti-platelet Study (STT-CLIPS)

Critical Limb Ischemia

United States
Moens Maarten

Completed

HRV in Patients Treated With Spinal Cord Stimulation

Failed Back Surgery Syndrome

Belgium
University of Alexandria

Completed

One Year Results of Switching to Aflibercept for Persistent Diabetic Macular Edema Resistant to Bevacizumab

Diabetic Macular Edema
University Hospital, Limoges

Unknown

PK Assessment of Tacrolimus Exposure Before and After a Switch From Twice Daily Immediate-release (Prograf®) to Once-daily Prolonged Release Tacrolimus (Envarsus®) (ENVARSWITCH)

Allograft

France
Actelion

Completed

Safety Study of the Switch From Oral Selexipag to Intravenous Selexipag in Subjects With Stable Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

United States, Germany
Novo Nordisk A/S

Completed

A Trial Comparing the Safety and Efficacy of Insulin Degludec and Insulin Glargine, With or Without OADs in Subjects With Type 2 Diabetes (SWITCH 2)

Diabetes Mellitus, Type 2 | Diabetes

United States, Puerto Rico
Mahidol University

Completed

Switching TDF/FTC/EFV to TDF/FTC/RPV VS Continuing TDF/FTC/EFV in HIV Patients With Complete Virological Suppression (STEREOS)

Dyslipidemias | HIV-1-infection | Sustained Virologic Response | Anti-Retroviral Agents | Efavirenz | Rilpivirine
Novo Nordisk A/S

Completed

Investigating the Effectiveness of Tresiba® (Insulin Degludec) After Switching Basal Insulin in a Population With Type 1 or Type 2 Diabetes Mellitus (EU-TREAT)

Diabetes Mellitus, Type 2 | Diabetes | Diabetes Mellitus, Type 1

Austria, Denmark, Greece, Germany, Switzerland, Italy
Kaohsiung Medical University Chung-Ho Memorial...

Unknown

TAF Switch in F3/4 CHB pt With Partial Response to NUC (ESTAB-AFPVR)

Hepatitis B | Fibrosis and Cirrhosis of Liver

Taiwan

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