Search clinical trials for: Metabolic responses

Total 57439 results

The George Institute
Peking University

Completed

China Plant Sterol Trial

Cardiovascular Diseases | Hypercholesterolemia

China
Mylan Bertek Pharmaceuticals

Completed

A Sub-Study With Patients in APO401 to Evaluate Adverse Events During Dose Introduction in Apomorphine-naïve Patients.

Parkinson Disease
Hospital de Sabadell
Bristol-Myers Squibb

Unknown

Multifactorial Intervention on Cardiovascular Risk Factors in Subjects With Peripheral Arterial Disease

Smoking | Hypertension | Diabetes Mellitus | Peripheral Arterial Disease | Hypercholesterolemia

Spain
Mylan Bertek Pharmaceuticals

Completed

Long Term Safety and Efficacy of SC Apomorphine in Treatment of "Off" Episodes in Late-Stage Parkinson's Disease

Parkinson Disease

United States
Stanford University
The Health Trust of Santa Clara County

Completed

Heart Disease on the Mend

Stroke | Hypertension | Coronary Heart Disease | Hyperlipidemia

United States
National Heart and Lung Institute
Wexham Park Hospital; 4th Military Hospital

Unknown

Effect of Intravenous Ferrous Sucrose on Exercise Capacity in Chronic Heart Failure

Heart Diseases | Anemia, Iron-Deficiency | Chronic Heart Failure

Poland, United Kingdom
Repligen Corporation

Terminated

RG2133 (2',3',5'-Tri-O-Acetyluridine) in Mitochondrial Disease

Mitochondrial Diseases
University of Southern Denmark
Pfizer

Completed

Atorvastatin and Endothelial Function in Type 2 Diabetes Mellitus (ATTEND-Study)

Type 2 Diabetes Mellitus

Denmark
Royal Brompton & Harefield NHS Foundation Trust
GlaxoSmithKline; CORDA, The Heart Charity

Unknown

Rosiglitazone Plaque Study

Vascular Diseases | Hypertension | Diabetes Mellitus, Type 2

United Kingdom
National Center for Research Resources (NCRR)
Oregon Health and Science University

Unknown

Phase II Study of Cholesterol- and Cholestanol-Free Diet, Lovastatin, and Chenodeoxycholic Acid for Cerebrotendinous Xanthomatosis

Cerebrotendinous Xanthomatosis

United States
Eunice Kennedy Shriver National Institute of Child...

Unknown

Evaluating the Effectiveness of a Dichloroacetate in MELAS Syndrome

MELAS Syndrome

United States
National Center for Research Resources (NCRR)
James Whitcomb Riley Hospital for Children

Completed

Phase II Pilot Study of Granulocyte Colony-Stimulating Factor for Inherited Bone Marrow Failure Syndromes

Thrombocytopenia | Dyskeratosis Congenita | Fanconi's Anemia | Shwachman Syndrome
National Center for Research Resources (NCRR)
Indiana University School of Medicine

Completed

Randomized Study of Pancrelipase With Bicarbonate (PANCRECARB) Capsules in Reducing Steatorrhea in Patients With Cystic Fibrosis

Cystic Fibrosis
National Center for Research Resources (NCRR)
University of Pennsylvania

Completed

Phase I Study of Ex Vivo Liver-Directed Gene Therapy for Familial Hypercholesterolemia

Familial Hypercholesterolemia
National Center for Research Resources (NCRR)

Completed

A Clinical Trial to Prevent the Complications of Insulin Resistance (Including Type-2 Diabetes)

Diabetes Mellitus | Insulin Resistance

United States
Glaxo Wellcome

Completed

A Study of Amprenavir in Patients With Protease Inhibitor-Related Complications

HIV Infections

United States
National Center for Research Resources (NCRR)
University of Pittsburgh

Unknown

Phase II Study of Glucocerebrosidase in Patients With Gaucher Disease

Gaucher's Disease

United States
National Center for Research Resources (NCRR)
Elizabeth Glaser Pediatric AIDS Foundation

Completed

The Metabolic Effects of Protease Inhibitors in HIV Infected Children

HIV Infections

United States
National Center for Research Resources (NCRR)
University of California, San Diego

Completed

Phase II Study of Ribose, Uridine, and Thymidine for a Complex Syndrome Involving Excessive 5'-Nucleotidase Activity

5'-Nucleotidase Syndrome
National Center for Research Resources (NCRR)

Completed

Continuously Infused Intracerebral (IC) Recombinant-Methionyl Human Glial Cell Line-Derived Neurotrophic Factor (r-metHuGDNF) for the Treatment of Idiopathic Parkinson's Disease

Parkinson Disease

United States
National Institute of Neurological Disorders and...
Baylor College of Medicine

Completed

Study of Phenotype and Genotype Correlations in Patients With Contiguous Gene Deletion Syndromes

Prader-Willi Syndrome | DiGeorge Syndrome | Williams Syndrome | Angelman Syndrome | Smith-Magenis Syndrome | Chromosome Abnormalities | Shprintzen Syndrome

United States
National Eye Institute (NEI)

Completed

Krypton-Argon Regression of Neovascularization Study (KARNS)

Diabetes Mellitus | Diabetic Retinopathy | Retinal Neovascularization
National Center for Research Resources (NCRR)
University of Texas

Completed

Phase I Study of Heme Arginate With or Without Tin Mesoporphyrin in Patients With Acute Attacks of Porphyria

Porphyria
University of Minnesota

Unknown

Phase I Pilot Study of CD34 Enriched, Fanconi's Anemia Complementation Group C Gene Transduced Autologous Peripheral Blood Stem Cell Transplantation in Patients With Fanconi's Anemia

Fanconi's Anemia
Glaxo Wellcome

Completed

A Study of the Effects of Amprenavir, a Protease Inhibitor, on Carbohydrate and Fat Metabolism in HIV-Infected Patients

HIV Infections

United States
National Center for Research Resources (NCRR)
University of California, Los Angeles

Completed

Stem Cell Transplantation (SCT) for Genetic Diseases

Thrombocytopenia | Inborn Errors of Metabolism | Metachromatic Leukodystrophy | Fanconi's Anemia | Thalassemia Major | Pure Red-Cell Aplasia

United States
Eunice Kennedy Shriver National Institute of Child...
University of Minnesota

Completed

Phase I/II Study of Retroviral-Mediated Transfer of Iduronate-2-Sulfatase Gene Into Lymphocytes of Patients With Mucopolysaccharidosis II (Mild Hunter Syndrome)

Mucopolysaccharidosis II

United States
National Center for Research Resources (NCRR)
Northwestern University

Completed

Randomized Placebo-Controlled Study of Aerobic Exercise and Resistance Training Plus Megestrol Acetate for HIV-Wasting

HIV Infections | Acquired Immunodeficiency Syndrome | HIV Wasting Syndrome
Duke University

Completed

Study of Axial Mobility Exercises in Parkinson Disease

Parkinson Disease
National Center for Research Resources (NCRR)
Northwestern University

Completed

Phase II Study of Lactulose and Circadian Rhythms in Patients With Cirrhosis

Hepatic Encephalopathy | Cirrhosis | Portal Hypertension
National Center for Research Resources (NCRR)
University of Virginia

Completed

Randomized Study of the Effect of Decreased Hyperinsulinemia on the Ovulatory Response to Clomiphene Citrate in Obese Women With Polycystic Ovary Syndrome

Polycystic Ovary Syndrome | Hyperinsulinism
Rockefeller University

Completed

A Study of Thalidomide in HIV-Infected Patients Who Are Receiving HAART

HIV Infections

United States
National Center for Research Resources (NCRR)

Unknown

Identification and Therapy Efficacy of Type 2 Diabetes in Hispanic Patients

Diabetes Mellitus, Non-Insulin-Dependent
Eunice Kennedy Shriver National Institute of Child...

Unknown

Preventing Osteoporosis in Adolescent Girls

Osteoporosis

United States
National Center for Research Resources (NCRR)
Duke University; Diabetes Trust Fund

Unknown

Screening Adolescents for Type 2 Diabetes Mellitus in a Community Clinic

Diabetes Mellitus

United States
Medical Research Laboratories International

Terminated

Implitapide in Patients With Hypertriglyceridemia (HTG) on Maximal, Concurrent Triglyceride-Lowering Therapy

Hypertriglyceridemia

United States, Netherlands, Norway
National Center for Research Resources (NCRR)
University of Texas

Completed

Study of Alpha-2 Adrenergic Receptor Dysfunction in Regional Lipoatrophy

Lipodystrophy

United States
National Center for Research Resources (NCRR)
Muscular Dystrophy Association

Completed

Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis [ALS]

Amyotrophic Lateral Sclerosis

United States
Medical Research Laboratories International

Terminated

Implitapide in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) on Maximal Concurrent Lipid-Lowering Therapy

Familial Hypercholesterolemia

Netherlands, United States, Norway
National Center for Research Resources (NCRR)

Completed

NNC 90-1170 Mechanism of Action: A Double-Blind, Randomized, Single-Center, Placebo-Controlled, Crossover Study to Examine Beta-Cell Responsiveness to Graded Glucose Infusion in Subjects With Type 2 Diabetes

Diabetes Mellitus, Non-Insulin-Dependent

United States
National Center for Research Resources (NCRR)
Indiana University School of Medicine

Unknown

Study of Systemic Amyloidosis Presentation and Prognosis

Amyloidosis

United States
University Hospital, Saarland

Unknown

Primary Prevention Study: Study on Obesity, Cardiovascular and Psycho-Social Characteristics in the City of Merzig

Depression | Obesity | Cardiovascular Disease | Stress

Germany
National Center for Research Resources (NCRR)

Unknown

Osteoporosis in Children and Adults Following Liver Transplantation

Liver Transplantation | Osteoporosis

United States
National Center for Research Resources (NCRR)

Unknown

The Inhibition of Platelet Antiaggregating Activity of Clopidogrel by Atorvastatin Detected by Erythromycin Breath Test: a Metabolic Inhibition of Hepatic Cytochrome P450-3A

Thrombosis | Hypercholesterolemia

United States
National Center for Research Resources (NCRR)
University of California, Los Angeles

Completed

Study of the Regulation of Parathyroid Hormone Secretion in Pseudohypoparathyroidism

Pseudohypoparathyroidism
National Center for Research Resources (NCRR)
Emory University

Completed

Phase II Study of Pallidotomy for Parkinson Disease

Parkinson Disease
National Center for Research Resources (NCRR)
University of Michigan

Completed

Phase II Study of the Enzyme Inhibitor NTBC for Tyrosinemia Type I

Tyrosinemia, Type I
Melbourne Health

Completed

Using the Drug Spironolactone to Test If It Reduces Protein Leakage From the Kidney

Diabetic Nephropathy | Proteinuria | Glomerulonephritis | Kidney Disease

Australia
National Center for Research Resources (NCRR)
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Establishment of a Database for Long-Term Monitoring of Patients With Nephropathic Cystinosis

Cystinosis

United States
National Center for Research Resources (NCRR)
University of Utah

Terminated

Study of Metabolic Effects of Pregnancy in Women With Cystic Fibrosis

Cystic Fibrosis

United States

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