Clinical Trials Sponsored by Decibel Therapeutics

Total 6425 results

VA Office of Research and Development
Helsinn Therapeutics (U.S.), Inc

Terminated

The Role of Ghrelin in Cancer Cachexia

Cancer Cachexia

United States
Johns Hopkins University
Juvenile Diabetes Research Foundation; iCo Therapeutics Inc.

Terminated

A Randomized, Multi-center, Phase II Study of the Safety, Tolerability and Bioactivity of Repeated Intravitreal Injections of iCo-007 as Monotherapy or in Combination With Ranibizumab or Laser Photocoagulation in the Treatment of Diabetic Macular Edema (the iDEAL Study) (iDEAL)

Diabetic Macular Edema

United States
Galera Therapeutics, Inc.
INC Research Australia Pty Ltd; Nucleous Network

Completed

A Study of the Safety, Tolerability and Pharmacokinetics of Orally-administered GC4702 in Healthy Volunteers

Healthy Volunteer

Australia
Schön Klinik Berchtesgadener Land
Grifols Therapeutics LLC; Alpha-1 Foundation

Completed

Effects of Exercise Training in Chronic Obstructive Pulmonary Disease Versus Alpha-1-Antitrypsin-deficiency-patients

Chronic Obstructive Pulmonary Disease | Alpha-1-antitrypsin-deficiency

Germany
Radboud University Medical Center
Dutch Heart Foundation; Synvista Therapeutics, Inc

Completed

Effects of Exercise Training and AGE-crosslink Breaker on Cardiovascular Structure and Function

Cardiovascular Disease | Physical Activity | Aging | Endothelial Dysfunction

Netherlands
University of Washington
National Institute on Aging (NIA); ASCEND Therapeutics

Completed

Effect of Dihydrotestosterone (DHT) on Prostate Tissue [Short Title: DHT-3] (DHT-3)

Healthy

United States
Rheumatology Therapeutics Medical Center
Kochan Institute for Healing Arts Research

Unknown

Safety and Efficacy Study of Bee Venom to Treat Knee Osteoarthritis

Persons With Mild to Moderate Knee Osteoarthritis

United States
Hepatitis Resource Network
Integrated Therapeutics Group; Subsidiary of Schering-Plough

Completed

PEG-Interferon a-2b + Ribavirin for Treatment of Chronic HRN 005 Hepatitis C Infection in HIV-Infected Persons Not Previously Treated With Interferon

HIV Infections | Chronic Hepatitis C Infection in HIV-Infected Persons

United States
Intira Sriprasert
TherapeuticsMD

Completed

Effect of Oral Estradiol and Progesterone Therapy on Vaginal Cytokines in Postmenopausal Women

Menopause

United States
Sight Medical Doctors PLLC
Ocular Therapeutix, Inc.

Completed

Intracanalicular Dexamethasone Insert for Post-Corneal Cross-Linking Inflammation and Pain- The LINK Study

Postoperative Pain | Keratoconus, Unstable | Collagen Crosslinking

United States
Lambda Therapeutic Research Ltd.
Intas Pharmaceutical Limited (Biopharma Division)

Recruiting

Denosumab Biosimilar Injection in Post Menopausal Women With Osteoporosis

Osteoporosis, Postmenopausal

India
Colorado State University
Hearts and Horses Therapeutic Riding Center

Completed

Piloting an Enhanced Protocol of Occupational Therapy in an Equine Environment for Youth With Autism

Autism Spectrum Disorder

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI); Karyopharm Therapeutics Inc

Not yet recruiting

Eltanexor and Venetoclax in Relapsed or Refractory Myelodysplastic Syndrome and Acute Myeloid Leukemia

Acute Myeloid Leukemia | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Refractory Myelodysplastic Syndrome | Relapsed Myelodysplastic Syndrome

United States
YANRU WANG
Rui Therapeutics Co., Ltd

Recruiting

A Clinical Study of CD19 CAR NK Cells for the Treatment of Relapsed/Refractory B-cell Related Autoimmune Diseases

Autoimmune Diseases

China
China Medical University, China
Beijing Bio-Targeting Therapeutics Technology Co., Ltd

Not yet recruiting

A Clinical Study of BioTTT001 in Combination With Toripalimab and Regorafenib in Patients With Colorectal Cancer

Colorectal Cancer Metastatic
Regend Therapeutics
Peking Union Medical College Hospital; RenJi Hospital; Ruijin Hospital

Recruiting

A Clinical Study to Evaluate the Efficacy and Safety of REGEND001 Cell Therapy on Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis

China
Cognition Therapeutics
National Institute on Aging (NIA); Alzheimer's Clinical Trials Consortium

Recruiting

A Study to Evaluate the Safety and Efficacy of CT1812 in Early Alzheimer's Disease

Early Alzheimer's Disease

United States
Second Affiliated Hospital, School of Medicine,...
TCRx Therapeutics Co.Ltd

Not yet recruiting

TCRx_T Cells for Advanced or Recurrent Gastric/Gastroesophageal Junction Cancer After Failure of First Chemotherapy

Gastric Cancer | Gastroesophageal-junction Cancer
Force Therapeutics
OSI Orthopedics and Sports Medicine; Rehab 360 Knee Glider

Not yet recruiting

Does an Active Range of Motion Monitor Improve Outcomes/Decrease Cost for Patients Undergoing Total Knee Arthroplasty?

Total Knee Arthroplasty (TKA)
Institut Bergonié
Roche Pharma AG; National Cancer Institute, France; Eikon Therapeutics

Recruiting

Atezolizumab Combined With BDB001 AnD Immunogenic Radiotherapy in Patients With Advanced Solid Tumors (AGADIR)

Melanoma | Pancreatic Cancer | Non Small Cell Lung Cancer | Bladder Cancer | Triple Negative Breast Cancer | Solid Tumor, Adult | Virus-associated Tumors

France
M.D. Anderson Cancer Center
National Cancer Institute (NCI); ADC Therapeutics S.A.

Recruiting

ADCT-602 in Treating Patients With Recurrent or Refractory B-cell Acute Lymphoblastic Leukemia

Recurrent B Acute Lymphoblastic Leukemia | Refractory B Acute Lymphoblastic Leukemia | Philadelphia Chromosome Positive | Blasts 5 Percent or More of Bone Marrow Nucleated Cells | CD22 Positive

United States
City of Hope Medical Center
National Cancer Institute (NCI); CytoImmune Therapeutics

Active, not recruiting

Genetically Engineered Natural Killer (NK) Cells With or Without Atezolizumab for the Treatment of Non-small Cell Lung Cancer Previously Treated With PD-1 and/or PD-L1 Immune Checkpoint Inhibitors

Metastatic Lung Non-Small Cell Carcinoma | Refractory Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Stage IIIC Lung Cancer... and other conditions

United States
CorrectSequence Therapeutics Co., Ltd
First Affiliated Hospital of Guangxi Medical University

Active, not recruiting

A Clinical Study Evaluating the Safety and Efficacy of CS-101 in Treating Subjects With β-thalassemia

Beta-Thalassemia

China
New Approaches to Neuroblastoma Therapy Consortium
Nationwide Children's Hospital; United Therapeutics

Active, not recruiting

Immunotherapy of Relapsed Refractory Neuroblastoma With Expanded NK Cells

Neuroblastoma

United States
Hunter College of City University of New York
Arcade Therapeutics Inc.

Completed

Effects of Therapeutic Mobile Game on Anxiety

Social Anxiety Disorder

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); Juno Therapeutics, Inc.

Completed

Immunotherapy With BCMA CAR-T Cells in Treating Patients With BCMA Positive Relapsed or Refractory Multiple Myeloma

Refractory Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma

United States
NCIC Clinical Trials Group
Cascadian Therapeutics Inc.

Completed

A Study of PX-866 in Patients With Glioblastoma Multiforme at Time of First Relapse or Progression

Glioblastoma

Canada
Canadian Medical and Surgical Knowledge Translation...
HLS Therapeutics, Inc

Completed

Generalizability of REDUCE-IT Results to People of South Asian Descent With Atherosclerotic Cardiovascular Disease in Canada (REDUCE-IT Canada SA)

Myocardial Infarction | Cardiovascular Diseases | Coronary Heart Disease | Atherosclerotic Cardiovascular Disease

Canada
H. Lee Moffitt Cancer Center and Research Institute
TG Therapeutics, Inc.

Terminated

TGR-1202 (Umbralisib) in Treatment Naïve Patients With Chronic Lymphocytic Leukemia (CLL)

Chronic Lymphocytic Leukemia

United States
Roger Williams Medical Center
University of Colorado, Denver; Sorrento Therapeutics, Inc.

Completed

CAR-T Hepatic Artery Infusions or Pancreatic Venous Infusions for CEA-Expressing Liver Metastases or Pancreas Cancer (HITM-SURE)

Liver Metastases

United States
Resolve Therapeutics
Newcastle-upon-Tyne Hospitals NHS Trust; University Hospital Birmingham

Completed

A Study of RSLV-132 in Subjects With Primary Sjogren's Syndrome (RSLV-132)

Sjogren's Syndrome

United Kingdom
Lisata Therapeutics, Inc.
California Institute for Regenerative Medicine (CIRM); Sanford Health

Completed

Safety and Efficacy of CLBS03 in Adolescents With Recent Onset Type 1 Diabetes (The Sanford Project T-Rex Study)

Diabetes Mellitus

United States
NeuroEM Therapeutics, Inc.
University of South Florida Health / Byrd Alzheimer's Institute

Unknown

Transcranial Electromagnetic Treatment Against Alzheimer's Disease

Alzheimer Disease | Alzheimer Disease, Late Onset

United States
Michael Vogelbaum, MD, PhD
Infuseon Therapeutics, Inc.

Terminated

Topotecan in Glioma Undergoing A Clinically-Indicated Surgical Resection

Brain Tumor | High Grade Glioma

United States
Dana-Farber Cancer Institute
Novartis; Pediatric Oncology Experimental Therapeutics Investigators' Consortium

Completed

Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas

Glioma | Astrocytoma | Low-grade Glioma

United States
Melinta Therapeutics, Inc.
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Efficacy and Safety Study of Oral Solithromycin Compared to Intramuscular Ceftriaxone Plus Oral Azithromycin in the Treatment of Patients With Gonorrhea (SOLITAIRE-U)

Uncomplicated Urogenital Gonorrhea

United States, Australia
Transdermal Therapeutics, Inc.
Albert Einstein College of Medicine; Montefiore Medical Center

Unknown

The Analgesic Activity of a Topical Formulation in Patients With Osteoarthritis of the Hands

Osteoarthritis of the Hands
PTC Therapeutics
Cystic Fibrosis Foundation; FDA Office of Orphan Products Development

Completed

PTC124 for Cystic Fibrosis

Cystic Fibrosis

United States
Sight Medical Doctors PLLC
Ocular Therapeutix, Inc.

Recruiting

Evaluation Of Vision Recovery And Comfort Index In Patients With Borderline/Mild Dry Eyes Undergoing FLACS With Premium IOL (ENHANCE)

Dry Eye Syndromes

United States
Eye Surgeons of Indiana
Ocular Therapeutix, Inc.

Completed

Lipiflow Treatment Alone vs. Lipiflow + Dextenza Treatment for Dry Eye Disease

Dry Eye Syndromes

United States
Eye Surgeons of Indiana
Ocular Therapeutix, Inc.

Terminated

Xiidra vs. Xiidra + Dextenza Treatment for Dry Eye Disease

Dry Eye Syndromes

United States
Therapeutic Advances in Childhood Leukemia Consortium
Bristol-Myers Squibb

Active, not recruiting

Nivolumab in Combination With 5-azacytidine in Childhood Relapsed/Refractory AML

AML, Childhood

United States
China Medical University, China
Beijing Bio-Targeting Therapeutics Technology Co., Ltd

Not yet recruiting

A Clinical Study of BioTTT001 in Combination With SOX and Toripalimab in Patients With Gastric Cancer

Gastric Cancer, Metastatic
The First Affiliated Hospital of Soochow University
CARsgen Therapeutics Co., Ltd.

Recruiting

CT0594CP CAR-T Cells in Patients With Relapsed/Refractory Multiple Myeloma or Plasma Cell Leukemia

Multiple Myeloma | Plasma Cell Leukemia

China
Modulation Therapeutics, Inc.
H. Lee Moffitt Cancer Center and Research Institute

Recruiting

Targeted Alpha Particle Radiotherapy for Metastatic Uveal Melanoma

Uveal Melanoma | Metastatic

United States
Karen Reckamp, MD, MS
Enviro Therapeutics, Inc.

Recruiting

Study of Osimertinib With Carotuximab in Advanced, EGFR-mutated Non-Small Cell Lung Cancer

Lung Cancer | Non Small Cell Lung Cancer

United States
The First Affiliated Hospital of Soochow University
CARsgen Therapeutics Co., Ltd.

Recruiting

A Study to Access the Safety and Efficacy of CT0590 in Patients With Relapsed and/or Refractory Multiple Myeloma

Relapsed and/or Refractory Multiple Myeloma

China
The First Affiliated Hospital of Soochow University
CARsgen Therapeutics Co., Ltd.

Recruiting

PBMC Collection for Production of UCAR T Cells

Peripheral Blood Mononuclear Cell

China
IVI Vigo
Instituto Valenciano de Infertilidad, IVI VALENCIA; Juno Therapeutics, Inc.

Not yet recruiting

Embryos With Preimplantation Genetic Testing for Aneuploidies (PGT-A) Inconclusive Result: Clinical Implications

Embryo Disorder
CorrectSequence Therapeutics Co., Ltd
First Affiliated Hospital of Guangxi Medical University

Enrolling by invitation

CS-101 in Patients With β-thalassemia

Beta-Thalassemia

China

Clinical Trials Sponsored by Decibel Therapeutics

Sponsors and Collaborators

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Drug Interventions

CROs by country

CROs in Slovenia

Conditions

Rare Diseases

Drug Interventions

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