Search clinical trials for: Checkpoint Inhibition

Total 6019 results

University of Patras

Completed

Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Reactivity in Patients With ST-elevation Myocardial Infarction (STEMI) (PRO-GR-4)

Myocardial Infarction

Greece
Changhai Hospital

Unknown

The Prophylactic Effect of Stilamin on Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis

Post-ERCP Acute Pancreatitis

China
University of Florida
Pfizer

Completed

Effect of Celecoxib on Markers of Vascular Inflammation

Hypertension and Coronary Artery Disease

United States
Frank A. Bucci, Jr., M.D.
Allergan

Completed

A Comparison of Prostaglandin E2 (PGE2) Inhibition of Acuvail(Ketorolac 0.45%), Xibrom (Bromfenac 0.09%)and Nevanac (Nepafenac)in Patients Undergoing Phacoemulsification

Cataracts
University Hospital, Ghent

Completed

Reciprocal Influence of Sex Steroid Environment and Adipocyte Function in Men

Healthy

Belgium
Assaf-Harofeh Medical Center

Completed

"Swallow my Urine Back" : Inhibition of Detrusor Overactivity by Swallowing Maneuver

Overactive Detrusor
University of Milan

Completed

Exercise Oscillatory Breathing and Sildenafil in Heart Failure

Heart Failure
Medical University of Vienna

Temporarily not available

Improvement of Myocardial Blood Flow by PhosphoDiesterase 5 Inhibition in Coronary Artery Disease (SYDNEY)

Coronary Artery Disease | Therapy Refractory Myocardial Ischemia | Unsuitable for Surgical or Percutaneous Revascularisation

Austria
Manhattan Psychiatric Center
Pfizer

Completed

Effect of Ziprasidone on Glucose & Plasma Lipids in Diabetes (II) and Schizophrenia or Schizoaffective Disorder

Schizophrenia | Schizoaffective Disorder

United States
Bayer

Completed

Ovulation Inhibition of Two 4-phasic Oral Contraceptive Regimens

Ovulation Inhibition

Germany, Netherlands
Bristol-Myers Squibb

Completed

MDX-010 Antibody, MDX-1379 Melanoma Vaccine, or MDX-010/MDX-1379 Combination Treatment for Patients With Unresectable or Metastatic Melanoma

Melanoma | Metastases

United States, Canada, Netherlands, United Kingdom, Germany, Chile, Belgium, France, South Africa, Argentina, Brazil, Hungary, Switzerland
China Medical University Hospital

Completed

D-amino Acid Oxidase Inhibition (DAAOI-1) add-on Treatment for Chronic Schizophrenia

Psychotic Disorders | Schizophrenic Disorders | Schizophrenias | Psychoses

Taiwan
Oslo University Hospital

Terminated

Coxib-inhibition of Duodenal Polyp Growth in FAP

Duodenal Polyposis

Norway
Bristol-Myers Squibb

Completed

Comparison Study of MDX-010 (CTLA-4) Alone and Combined With Docetaxel in the Treatment of Patients With Hormone Refractory Prostate Cancer

Prostate Cancer

United States
vTv Therapeutics

Completed

Safety Study of the Inhibition of Agouti-related Protein (AgRP) for the Management of Obesity and Weight Loss

Obesity

United States, Canada
Bristol-Myers Squibb

Completed

Substudy - Low Dose of Abatacept in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis
Dart NeuroScience, LLC

Terminated

Study of the Inhibition of [11C]R-rolipram Binding to Brain Phosphodiesterase - 4 (PDE-4) by HT-0712

Healthy Elderly Volunteers

United States
Bristol-Myers Squibb

Completed

A Study of Abatacept in Japanese Patients With Active Rheumatoid Arthritis While Receiving Methotrexate

Rheumatoid Arthritis

Japan
Bristol-Myers Squibb

Completed

Phase II Randomized, Double-Blind, Placebo-Controlled Study of BMS-188667 (CTLA4Ig) in Patients With Psoriasis Vulgaris

Psoriasis Vulgaris

United States
Heidelberg University
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Unknown

Prasugrel Versus Clopidogrel in Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI)

Patients With Acute Coronary Syndrome

Germany
Bristol-Myers Squibb

Completed

Comparability DE vs CD-CHO1

Healthy Subjects

United Kingdom
Bristol-Myers Squibb

Completed

A Study to Assess the Pharmacokinetics, Immunogenicity and Safety of Escalating Doses of BMS-188667 Given as a Single Intravenous Infusion to Patients With Psoriasis Vulgaris

Psoriasis Vulgaris

United States
Bristol-Myers Squibb

Completed

Phase I Study of BMS-188667 (CTLA4Ig) in Patients With Psoriasis Vulgaris

Psoriasis Vulgaris

United States
Bristol-Myers Squibb

Completed

Vaccination Study of Abatacept (BMS-188667) for Normal Healthy Volunteers

Rheumatoid Arthritis

United States
University Hospital, Angers

Unknown

Study of Cognitive Inhibition Disorders in Depressed Older Suicide Attempters (ETIC)

Suicide, Attempted | Cognitive Symptoms

France
Kyunghee University Medical Center

Completed

Effect of Platelet Inhibition According to Clopidogrel Dose in Patients With Chronic Kidney Disease (CKD)

Chronic Kidney Disease | Stable Angina

Korea, Republic of
Bristol-Myers Squibb

Completed

Comparison Study of MDX-010 (CTLA-4) Alone and Combined With DTIC in the Treatment of Metastatic Melanoma

Melanoma

United States
AstraZeneca
POZEN

Completed

A Study Assessing Inhibition of Serum Thromboxane B2 Levels With PN400 and Low Dose Aspirin

Platelet Inhibition

United States
Bristol-Myers Squibb

Terminated

A Study to Evaluate the Preliminary Efficacy Pharmacokinetics and Immunogenicity of BMS-188667 Administered to Subjects With Relapsing-remitting Multiple Sclerosis

Multiple Sclerosis

United States
Bristol-Myers Squibb

Completed

The Study of Abatacept in Combination With Etanercept

Rheumatoid Arthritis

United States
Austin Health
Royal North Shore Hospital; Ballarat Health Services; Queen Elizabeth Hospital...

Unknown

Dual Inhibition of EGFR Signalling Using the Combination of Cetuximab and Erlotinib (Dux)

Metastatic Colorectal Cancer

Australia
Bristol-Myers Squibb

Completed

Remission and Joint Damage Progression in Early Rheumatoid Arthritis

Rheumatoid Arthritis

Korea, Republic of, United States, Spain, Puerto Rico, Belgium, Australia, Canada, Mexico, France, Germany, Netherlands, Russian Federation, South Africa, United Kingdom, Brazil, Czech Republic, Italy, Poland
National Eye Institute (NEI)

Completed

Vascular Remodeling and the Effects of Angiogenic Inhibition in Diabetic Retinopathy

Diabetic Retinopathy

United States
China Medical University Hospital

Unknown

The Variation of Movement Related Cortical Potential, Cortico-cortical Inhibition, and Motor Evoked Potential in Intracerebral Implantation of Antologous Peripheral Blood Stem Cells(CD34)in Old Ischemic Stroke

Stroke

Taiwan
Rijnstate Hospital

Completed

Short-term Effects of Aromatase Inhibition in Obese Men

Obesity | Hypogonadotrophic Hypogonadism

Netherlands
Massachusetts General Hospital
National Institute of Mental Health (NIMH)

Completed

Early Intervention for Children at Risk for Anxiety

Anxiety Disorder

United States
Assaf-Harofeh Medical Center

Unknown

Correlation Between CYP2C19 Genotype, Level Of Clopidogrel Metabolite And Platelet Inhibition Status

PRIMARY FOCUS:PATIENT THAT TAKE CLOPIDOGREL

Israel
National Heart, Lung, and Blood Institute (NHLBI)
Pediatric Heart Network

Completed

Trial of Angiotensin Converting Enzyme Inhibition in Infants With Single Ventricle--Pediatric Heart Network (ISV)

Heart Defects, Congenital | Heart Failure, Congestive

United States, Canada
AstraZeneca

Terminated

Oral AZD8165 After Single Oral Ascending Doses in Healthy Male Subjects

Thrombin Inhibition

United States
Bristol-Myers Squibb

Terminated

A Study of Abatacept in Patients With Active Crohn's Disease

Crohn's Disease

Australia, India, United States, Canada, Brazil, Mexico, Puerto Rico, Switzerland, Italy, Belgium, Netherlands, Denmark, France, Germany, South Africa, Czech Republic, Poland
Hanmi Pharmaceutical Company Limited

Completed

Duration of P-glycoprotein Inhibition After Oral Administration of HM30181AK Tablet (PGP inhibitor)

Healthy

Korea, Republic of
Vrije Universiteit Brussel
Research Foundation Flanders

Unknown

Diffuse Noxious Inhibitory Controls (DNIC): Nociceptive Modulation and Interaction With Neurocognitive Performance in Chronic Pain

Chronic Pain | Fibromyalgia | Whiplash

Belgium
Shriners Hospitals for Children
United Cerebral Palsy Foundation

Completed

The Effect of Botox on Children With Cerebral Palsy

Cerebral Palsy

United States
Vrije Universiteit Brussel

Completed

Influence of Painphysiolgy Education on the Pain Inhibition in Fibromyalgia

Fibromyalgia

Belgium
Vrije Universiteit Brussel
University Hospital, Antwerp; Universiteit Antwerpen; Research Foundation Flanders and other collaborators

Unknown

Pain Inhibition in Patients With Rheumatoid Arthritis and Central Sensitivity Syndromes

Arthritis, Rheumatoid | Fibromyalgia | Fatigue Syndrome, Chronic

Belgium
R&D Cardiologie

Completed

Platelet Inhibition and Transcranial Doppler (TCD)-Detected Microemboli During and After Carotid Artery Stenting (CAS) in Asymptomatic Patients Prior to Cardiac Surgery (IMPACT)

Carotid Stenosis

Netherlands
Centers for Disease Control and Prevention
PATH; World Health Organization; MCM Vaccines B.V.; Pan American Health Organization and other collaborators

Completed

Needle-free Jet Injection of Reduced-dose, Intradermal, Influenza Vaccine in >= 6 to < 24-month-old Children

Influenza

Dominican Republic
Bristol-Myers Squibb

Completed

Study of MDX-010 in Subjects With Unresectable Stage III or Stage IV Malignant Melanoma

Malignant Melanoma

United States
Bristol-Myers Squibb

Completed

A Study of MDX-1106 to Treat Patients With Hepatitis C Infection (MDX1106-02)

Hepatitis C

United States
Uppsala University

Completed

Tailoring Of Platelet Inhibition to Avoid Stent Thrombosis (TOPAS-1)

Myocardial Infarction | Heart Diseases | Coronary Artery Disease | Acute Coronary Syndrome | Stent Thrombosis

Sweden

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