Clinical Trials Sponsored by Aptevo Therapeutics

Total 6345 results

University Hospital, Bordeaux
APTES 100 rue boileau 69006 Lyon

Completed

Thalamic LFPs and VIM DBS in Essential Tremor: Correlation, Evolution, and Therapeutic Perspectives (VIM-CLT)

Essential Tremor

France
Melinta Therapeutics, LLC

Recruiting

Study to Evaluate the Safety and Tolerability of Single-Dose Intravenous (IV) Oritavancin

Acute Bacterial Skin and Skin Structure Infection

United States, Spain, Greece, Portugal, Bulgaria, Latvia, Romania, Lithuania, Poland
Windtree Therapeutics
CVie Therapeutics Co. Ltd.

Completed

The Clinical Study of the Safety and Efficacy of Istaroxime in Treatment of Acute Decompensated Heart Failure

Acute Decompensated Heart Failure

China, Italy
Millendo Therapeutics SAS

Terminated

Effects of Livoletide (AZP-531) on Food-related Behaviors in Patients With Prader-Willi Syndrome (ZEPHYR)

Hyperphagia | Prader-Willi Syndrome

United States, Belgium, Spain, France, Italy, United Kingdom, Australia, Netherlands
United Therapeutics
CVie Therapeutics Co. Ltd.

Withdrawn

An Open Label Extension Study to Evaluate the Safety of Continued Therapy of Subcutanous Remodulin® in Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

China
United Therapeutics
CVie Therapeutics Co. Ltd.

Withdrawn

Safety, Tolerability, Pharmacokinetics and Efficacy of Two Different Rates of Subcutanous Remodulin® Dose Titration in Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

China
Celldex Therapeutics

Not yet recruiting

A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU) (EMBARQ-CSU2)

Chronic Spontaneous Urticaria
PYC Therapeutics

Not yet recruiting

MAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects (Wallaby)

Eye Diseases | Retinal Degeneration | Retinal Dystrophies | Retinal Disease | Retinitis Pigmentosa 11

United States
SURGE Therapeutics

Not yet recruiting

Study of STM-416p Administered to Patients Undergoing Radical Prostatectomy

Prostate Cancer
Celldex Therapeutics

Not yet recruiting

A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (EMBARQ-CSU1)

Chronic Spontaneous Urticaria
Primoris Therapeutics

Not yet recruiting

A Study to Evaluate the Safety, Tolerability and Efficacy in Patients With Burn(s)

Burns | Burn Degree Second
Verismo Therapeutics

Recruiting

Long-Term Follow-Up Safety Study of Subjects Treated With SynKIR-110 in Cancer Studies

Cancer

United States
Adicet Therapeutics

Not yet recruiting

A Phase 1 Study of ADI-001 in Lupus Nephritis

Autoimmune Diseases | Lupus Nephritis
Ractigen Therapeutics.

Recruiting

A Study of RAG-01 in Patients With Non-muscle-invasive Bladder Cancer (NMIBC) Who Have Failed Bacillus Calmette Guérin (BCG) Therapy

Non-Muscle-Invasive Bladder Cancer (NMIBC)

Australia
NeuShen Therapeutics

Recruiting

First-into-human Study of NS-136 in Healthy Subjects

Healthy Subjects

Australia
Monopar Therapeutics

Recruiting

Diagnostic Efficacy and Dosimetry of MNPR-101-DFO*-89Zr in Patients With Solid Tumors

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Lung Cancer | Bladder Cancer | Urothelial Carcinoma | Triple-negative Breast Cancer | Solid Tumor, Adult

Australia
vTv Therapeutics

Not yet recruiting

Cadisegliatin as Adjunctive Therapy in Type 1 Diabetes (CATT1)

Diabetes Mellitus, Type 1
Enliven Therapeutics

Recruiting

ELVN-002 With Trastuzumab +/- Chemotherapy in HER2+ Solid Tumors, Colorectal and Breast Cancer

Colorectal Cancer | HER2-positive Breast Cancer | HER2-positive Gastric Cancer | HER2 Amplification | HER2 Positive Solid Tumors

United States
OX2 Therapeutics

Recruiting

CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young Adults

Diffuse Midline Glioma, H3 K27M-Mutant | Recurrent High Grade Glioma

United States
Transcend Therapeutics

Recruiting

A Single, Ascending Dose Evaluation of the Safety, Pharmacokinetics of Methylone in Healthy Subjects

Post Traumatic Stress Disorder

Australia
Remix Therapeutics

Recruiting

Study of REM-422 in Patients With AML or Higher Risk MDS

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Acute Myeloid Leukemia Refractory | Higher Risk Myelodysplastic Syndromes

United States
Dianthus Therapeutics

Recruiting

A Phase 2 Study to Evaluate DNTH103 in Adults With Generalized Myasthenia Gravis (MAGIC) (MAGIC)

Myasthenia Gravis, Generalized

United States
Encoded Therapeutics

Recruiting

A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome (UK Only)

Dravet Syndrome

United Kingdom
Aprea Therapeutics

Recruiting

Study of APR-1051 in Patients With Advanced Solid Tumors (ACESOT-1051)

Advanced Solid Tumor

United States
ReCode Therapeutics

Recruiting

A Phase 1 Study Evaluating Safety and Tolerability of RCT2100 in Healthy Participants

Cystic Fibrosis

New Zealand
Repare Therapeutics

Recruiting

LIONS (PLK4 Inhibitor in Advanced Solid Tumors)

Advanced Solid Tumor

United States
NovelMed Therapeutics

Not yet recruiting

Study of NM8074 in Patients With Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis (AAV)

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Quanta Therapeutics

Recruiting

QTX3034 in Patients With KRAS G12D Mutation

Solid Tumors

United States
Transcend Therapeutics

Not yet recruiting

An Evaluation of the Safety and Efficacy of Methylone for the Treatment of PTSD (IMPACT-2)

Post Traumatic Stress Disorder

Australia
Atamyo Therapeutics

Not yet recruiting

Natural History Study in Patients With LGMDR5/2c

Gamma-sarcoglycanopathy

France, Tunisia
Odyssey Therapeutics

Recruiting

Phase 1 Study to Investigate OD-07656 in Healthy Adult Participants

Inflammatory Bowel Diseases | Crohn Disease | Ulcerative Colitis | Spondyloarthritis | Blau Syndrome

Australia
Orchard Therapeutics

Recruiting

A Study to Investigate the Efficacy and Safety of OTL-203 in Subjects With MPS-IH Compared With Standard of Care With Allogeneic HSCT (HURCULES)

MPS-IH (Hurler Syndrome)

Netherlands, United States, Italy, United Kingdom
Nektar Therapeutics

Recruiting

A Phase 2b Study to Evaluate Rezpegaldesleukin (Rezpeg) in the Treatment of Adult Patients With Moderate-to-Severe Atopic Dermatitis (REZOLVE-AD)

Moderate to Severe Atopic Dermatitis

Spain, Czechia, United States, Australia, Croatia, Bulgaria, Poland, Canada, Germany, Hungary
Karuna Therapeutics

Recruiting

A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)

Psychosis Associated With Alzheimer's Disease

United States, Korea, Republic of, Chile, Greece, Poland
Lexeo Therapeutics

Recruiting

Gene Therapy for ACM Due to a PKP2 Pathogenic Variant

Arrhythmogenic Cardiomyopathy | PKP2-ACM | PKP2-ARVC

United States
Corcept Therapeutics

Recruiting

A Phase 2b, Study Evaluating Miricorilant in Adult Patients With Nonalcoholic Steatohepatitis/Metabolic Dysfunction-Associated Steatohepatitis (MONARCH)

Nonalcoholic Steatohepatitis (NASH) | Metabolic Dysfunction-associated Steatohepatitis (MASH)

United States, Puerto Rico
Epion Therapeutics

Recruiting

Epithelium-On Corneal Cross-linking in Subjects 8 to 45 Years of Age With Keratoconus (Apricity-A)

Keratoconus

United States
Dermata Therapeutics

Recruiting

DMT310-009 Topical in the Treatment of Acne Vulgaris

Acne Vulgaris

United States
MBrace Therapeutics

Recruiting

Safety & PK of MBRC-101 in Advanced Refractory Solid Tumors

Cancer

United States
Atamyo Therapeutics

Not yet recruiting

ATA-200 Dose-escalation Gene Therapy Trial in Patients With LGMDR5

LGMD2C

France, Italy
CARGO Therapeutics

Recruiting

A Phase 2 Study of Firi-cel in Patients With Relapsed/Refractory Large B-cell Lymphoma (FIRCE-1)

Cancer | Relapsed/Refractory Large B-cell Lymphoma (LBCL)

United States
Trevi Therapeutics

Recruiting

Refractory Chronic Cough Improvement Via NAL ER (RIVER) (RIVER)

Refractory Chronic Cough

Canada, United Kingdom
Trevi Therapeutics

Recruiting

Cough Reduction in IPF With Nalbuphine ER (CORAL)

Idiopathic Pulmonary Fibrosis

United Kingdom, Australia, Netherlands, Spain, Italy, Turkey, Poland, Chile, Canada, Germany
United Therapeutics

Recruiting

Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)

Interstitial Lung Disease | Progressive Pulmonary Fibrosis

United States, Canada
Cingulate Therapeutics

Recruiting

Phase 3 Efficacy and Safety Laboratory Classroom Study in Pediatrics (6-12) With ADHD Using CTx-1301

ADHD | Attention Deficit Hyperactivity Disorder | Attention Deficit Disorder With Hyperactivity | ADHD - Combined Type | Attention Deficit Hyperactivity Disorder Combined | Attention Deficit Hyper Activity | Attention-deficit Hyperactivity

United States
Stemirna Therapeutics

Not yet recruiting

A Phase II/III Study to Evaluate the Immunogenicity and Safety and Efficacy of SWIM816 Vaccines for SARS-CoV-2

Safety | Immunogenicity
Vaxiion Therapeutics

Recruiting

Phase 1 Study of Intratumoral Administration of VAX014 in Subjects With Advanced Solid Tumors

Advanced Solid Tumor

United States
Otovia Therapeutics

Recruiting

An Investigator Initiated Study for OTOV101N+OTOV101C Injection

DFNB9

China
Aligos Therapeutics

Recruiting

A Study in Healthy Volunteers to Evaluate the Safety, Tolerability, Pharmacokinetics, and Drug-Drug Interaction Potential of Single and Multiple Doses of ALG-097558

COVID-19

United Kingdom
Areteia Therapeutics

Recruiting

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma (EXHALE-3) (EXHALE-3)

Asthma | Eosinophilic Asthma | Asthma; Eosinophilic

United States, South Africa, United Kingdom, Korea, Republic of

Clinical Trials Sponsored by Aptevo Therapeutics

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Argentina

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations