Clinical Trials Sponsored by Children's Center for Digestive Health Care

Total 673 results

University of Minnesota
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Washington... and other collaborators

Recruiting

Natural History and Structural Functional Relationships in Fabry Renal Disease Treatment Outcomes(Changes)in Fabry Renal Disease Study (LDN6702)

Fabry Disease

United States
Daping Hospital and the Research Institute of Surgery...
The First Affiliated Hospital of Anhui Medical University; LanZhou University; Beijing 302 Hospital and other collaborators

Withdrawn

Selective High Frequency Oscillatory Ventilation (HFOV) for Neonates

Acute Respiratory Distress Syndrome | Respiratory Distress Syndrome | High Frequency Oscillatory Ventilation

China
Menzies Institute for Medical Research
Yale University; University Medical Center Groningen; University of Southern... and other collaborators

Unknown

OPTIMIST-A Trial: Minimally-invasive Surfactant Therapy in Preterm Infants 25-28 Weeks Gestation on CPAP (OPTIMIST-A)

Bronchopulmonary Dysplasia

Australia, United States, New Zealand, Israel, Slovenia, Turkey
Public Health Foundation Enterprises, Inc.
National Institute on Drug Abuse (NIDA); Eunice Kennedy Shriver National Institute... and other collaborators

Completed

Comparison of Men's Prevention Apps to Research Efficacy (COMPARE)

Sexually Transmitted Diseases | HIV/AIDS | Risk Reduction | Pre-exposure Prophylaxis

United States
National Institute of Diabetes and Digestive and...
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

The Diabetes Prevention Trial of Type 1 Diabetes (DPT-1) (DPT-1)

Diabetes Mellitus, Type 1

United States, Canada
Memorial Sloan Kettering Cancer Center
Johns Hopkins University; Massachusetts General Hospital; Fox Chase Cancer Center and other collaborators

Active, not recruiting

Does Cefoxitin or Piperacillin-Tazobactam Prevent Postoperative Surgical Site Infections After Pancreatoduodenectomy?

Pancreatic Cancer | Pancreatic Diseases | Pancreas Cancer

United States, Canada
University of Pennsylvania
National Heart, Lung, and Blood Institute (NHLBI); National Institute of Arthritis... and other collaborators

Active, not recruiting

The Assessment of Prednisone In Remission Trial - Centers of Excellence Approach (TAPIR)

Granulomatosis With Polyangiitis

United States, Canada
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Completed

Action to Control Cardiovascular Risk in Diabetes (ACCORD) (ACCORD)

Cardiovascular Diseases | Coronary Disease | Hypertension | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Atherosclerosis | Hypercholesterolemia

United States, Canada
University Medical Center Groningen
Karolinska Institutet; National University Hospital, Singapore; Hospital Italiano... and other collaborators

Enrolling by invitation

Hepatic Artery Stenosis and Thrombosis After Liver Transplantation in Children (HEPATIC)

Pediatric ALL | Liver Transplant; Complications | Hepatic Artery Thrombosis | Hepatic Artery Stenosis

Netherlands
East Bay Institute for Research and Education
University of California, Davis; University of California, Irvine; Kaiser Permanente and other collaborators

Completed

Effect of ERCP Mechanical Simulator (EMS) Practice on Endoscopic Retrograde Cholangiopancreatography (ERCP) Training (ERCP)

Training

United States
University of Washington
University of Colorado, Denver; Massachusetts General Hospital; Mayo Clinic; Oregon... and other collaborators

Completed

Lumbar Epidural Steroid Injections for Spinal Stenosis Multicenter Randomized, Controlled Trial (LESS Trial) (LESS)

Low Back Pain | Spinal Stenosis

United States
Andrew Steer
National Health and Medical Research Council, Australia; Queen Fabiola Children... and other collaborators

Completed

Controlled Human Infection for Vaccination Against Streptococcus Pyogenes (CHIVAS)

Bacterial Infections | Gram-Positive Bacterial Infections | Strep Throat | Streptococcus Pharyngitis | Streptococcus Pyogenes Pharyngitis | Streptococcus Pyogenes Infection | Group A Streptococcus: B Hemolytic Pharyngitis | Group A Streptococcal Infection

Australia
Anne Katrine Pagsberg
Albert Einstein College of Medicine; The Research Council for Health and Disease... and other collaborators

Unknown

Tolerance and Effect of Antipsychotics in Children and Adolescents With Psychosis (TEA)

Psychosis

Denmark
Daping Hospital and the Research Institute of Surgery...
The First Affiliated Hospital of Anhui Medical University; LanZhou University; Beijing 302 Hospital and other collaborators

Completed

A Trial Comparing Noninvasive Ventilation Strategies in Preterm Infants Following Extubation

Intubated Infants Were Intend to Extubation Using Noninvasive Ventilation Strategies

China
Milton S. Hershey Medical Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University... and other collaborators

Not yet recruiting

Closed Loop and Education for Hypoglycemia Awareness Restoration (CLEAR)

Diabetes Mellitus, Type 1

United States, Australia, United Kingdom
University of Chicago
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Completed

Lysosomal Storage Disease: Health, Development, and Functional Outcome Surveillance in Preschool Children

Krabbe Disease | Mucopolysaccharidosis Type II (MPS II) | Mucopolysaccharidosis Type I (MPS I) | Mucopolysaccharidosis Type III (MPS III) | Mucopolysaccharidosis Type VI (MPS VI)

United States
Wits Health Consortium (Pty) Ltd
Fred Hutchinson Cancer Center; Janssen Vaccines & Prevention B.V.; National Institute... and other collaborators

Completed

Sisonke (Together): OPEN LABEL TRIAL COVID-19 (Sisonke)

SARS (Severe Acute Respiratory Syndrome)

South Africa
The Hospital for Sick Children
Baylor College of Medicine; Johns Hopkins Bloomberg School of Public Health; United... and other collaborators

Completed

Encapsulated Calcium Absorption in Pregnancy (ENCAP)

Pregnancy

Canada, United States, Bangladesh
Sharp HealthCare
University of Alabama at Birmingham; University of Pittsburgh; University of... and other collaborators

Recruiting

Two Year Developmental Follow-up for PREMOD2 Trial (Premature Infants Receiving Milking or Delayed Cord Clamping) (PREMOD2FU)

Neurodevelopmental Abnormality

United States, Ireland, Canada, Germany
Harvard Pilgrim Health Care
Duke University; Brigham and Women's Hospital; University of California, San... and other collaborators

Active, not recruiting

CLUSTER Trial for Outbreak Detection and Response (CLUSTER)

Cluster Detection

United States
Dana-Farber Cancer Institute
Johns Hopkins University; Baylor College of Medicine; Washington University School... and other collaborators

Completed

A Phase II Trial of Regadenoson in Sickle Cell Anemia

Sickle Cell Anemia

United States
Sharp HealthCare
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Premature Infants Receiving Milking or Delayed Cord Clamping: PREMOD2 (PREMOD2)

Death; Neonatal | Intraventricular Haemorrhage Neonatal

United States, Ireland, Canada, Germany
Foundation for Professional Development (Pty) Ltd
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Recruiting

Clinical Study of STI Screening to Prevent Adverse Birth and New-born Outcomes

HIV/AIDS | Pregnancy | Cost-effectiveness | Antenatal Care | Chlamydia Trachomatis | Vaginal Microbiome | Birth Outcomes | Sexually Transmitted Infection | Neisseria Gonorrhoeae | Trichomonas Vaginalis

South Africa
agnes chen
University of California, Los Angeles; National Institute of Neurological Disorders... and other collaborators

Terminated

Extension Study of Intrathecal Enzyme Replacement for Cognitive Decline in MPS I

Mucopolysaccharidosis I | Cognitive Decline

United States
James Dowling
Canadian Institutes of Health Research (CIHR); Cures Within Reach; The Joshua... and other collaborators

Recruiting

Tamoxifen Therapy for Myotubular Myopathy (TAM4MTM)

X Linked Myotubular Myopathy

United Kingdom, Canada, United States
FHI 360
University of Washington; University of North Carolina, Chapel Hill; World Health... and other collaborators

Completed

The Evidence for Contraceptive Options and HIV Outcomes Trial (ECHO)

HIV | Contraception

Kenya, South Africa, Swaziland, Zambia
State University of New York at Buffalo
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Krabbe Disease Global Patient Registry

Krabbe Disease

United States
University of Bern
University of Alabama at Birmingham; University of Southern California; Louisiana... and other collaborators

Active, not recruiting

Genital Tract Infections, the Vaginal Microbiome and Gestational Age at Birth Among Pregnant Women in South Africa

HIV Infections | Premature Birth | Microbial Colonization | Pregnancy; Infection | Bacterial Vaginosis | Trichomonas Vaginitis | Neisseria Gonorrheae Infection | Chlamydia Trachomatis Infection | Mycoplasma Genitalium Infection | Genital Mycoplasma Infection | Vaginal Candida | Sexually Transmitted Infections... and other conditions

South Africa
University of California, Irvine
Harvard Medical School (HMS and HSDM); National Institute of Allergy and Infectious... and other collaborators

Completed

Active Bathing to Eliminate Infection (ABATE Infection) Trial (ABATE)

Methicillin Resistant Staphylococcus Aureus | Multi Drug Resistant Organisms | Healthcare Associated Infections

United States
The Cooper Health System
Medical University of South Carolina; University of Colorado, Denver; Mayo Clinic and other collaborators

Enrolling by invitation

Cardiac Abnormalities in Stroke Prevention and Risk of Recurrence (CASPR)

Cryptogenic Stroke

United States
National Institute of Diabetes and Digestive and...
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Improving Metabolic Assessments in Type 1 Diabetes Mellitus Clinical Trials

Diabetes Mellitus, Type 1

United States, Australia, Canada, Finland, Italy, United Kingdom
NICHD Global Network for Women's and Children's...
University of Colorado, Denver; University of Alabama at Birmingham; University... and other collaborators

Completed

First Bites: Complementary Feeding - A Global Network Cluster Randomized Controlled Trial (First Bites)

Complementary Feeding | Infant Growth

Congo, Guatemala, Pakistan, Zambia
National Institute of Diabetes and Digestive and...
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

New Onset of Type 1 Diabetes Mycophenolate Mofetil-Daclizumab Clinical Trial (TN02)

Diabetes Mellitus, Type 1

United States, Canada
Ludwig-Maximilians - University of Munich
Bavarian State Ministry of Environment, Public Health and Consumer Protection and other collaborators

Completed

Population Based Intervention to Prevent Obesity in Kindergartens (TigerKids)

Obesity
Children's National Research Institute
Patient-Centered Outcomes Research Institute; Eunice Kennedy Shriver National... and other collaborators

Completed

PCORI Urea Cycle Disorder Study

Urea Cycle Disorders

United States
Mazonson & Santas Inc.
Icahn School of Medicine at Mount Sinai; ViiV Healthcare; AIDS Healthcare Foundation and other collaborators

Recruiting

Advancing Dignity, Health, and Optimism in Connection With Long Acting Injectables (ADHOC-LA)

HIV

United States
Radboud University Medical Center
Amsterdam UMC, location VUmc; ZonMw: The Netherlands Organisation for Health... and other collaborators

Recruiting

Effectiveness of Focal Therapy in Men With Prostate Cancer (ENFORCE)

Prostate Cancer | Prostate Neoplasm

Netherlands
West China Hospital
Beijing Friendship Hospital; Obstetrics and Gynecology Hospital of Zhejiang... and other collaborators

Completed

Epidemiological Study of Iron Deficiency and Iron Deficiency Anemia in Chinese Pregnant Women (EIDACPW)

Anemia, Iron-Deficiency

China
Boston Children's Hospital
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health... and other collaborators

Recruiting

A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202) (TransIT)

Severe Aplastic Anemia

United States
University Hospitals, Leicester
University of Leipzig; Technische Universität Dresden; University of Leicester; The Algarve Regional Health Administration and other collaborators

Completed

Prevention Strategies for Adolescents at Risk of Diabetes (PRE-STARt)

Type 2 Diabetes | Chronic Disease

United Kingdom
National Institute of Diabetes and Digestive and...
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Active, not recruiting

TEDDY - The Environmental Determinants of Diabetes in the Young

Type 1 Diabetes Mellitus

United States, Finland, Germany, Sweden
Gregory K. Friedman, MD
Memorial Sloan Kettering Cancer Center; United States Department of Defense; Food... and other collaborators

Completed

HSV G207 Alone or With a Single Radiation Dose in Children With Progressive or Recurrent Supratentorial Brain Tumors

Glioblastoma | Malignant Glioma | PNET | Anaplastic Astrocytoma | Embryonal Tumor | Supratentorial Neoplasms, Malignant | Cerebral Primitive Neuroectodermal Tumor

United States
University of Alabama at Birmingham
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Natural History of Rett Syndrome & Related Disorders

Rett Syndrome | CDKL5 Disorder | MECP2 Duplication dIsorder | FOXG1 Syndrome

United States
University of Alabama at Birmingham
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Biobanking of Rett Syndrome and Related Disorders

CDKL5 | Rett Syndrome | MECP2 Duplication | FOXG1 Disorders

United States
University of Manchester
Northern Care Alliance NHS Foundation Trust; Royal Free Hospital NHS Foundation... and other collaborators

Enrolling by invitation

Early Diagnosis of SSc in the General Rheumatology Clinic - Pilot

Systemic Sclerosis | Raynaud Phenomenon

United Kingdom
Sharp HealthCare
Children's Hospital of Philadelphia; University of South Florida; Yale University and other collaborators

Not yet recruiting

NICU Antibiotics and Outcomes (NANO) Follow-up Study (NANO-FU)

Premature Birth | Antibiotics | Neurodevelopment

United States, Canada
Royal College of Surgeons, Ireland
The Hospital for Sick Children; Massachusetts General Hospital; Belfast Health... and other collaborators

Not yet recruiting

ENHANCE- Establishing Natural History in an Advanced New CF Care Era

Cystic Fibrosis
Texas Cardiac Arrhythmia Research Foundation
Stanford University; University of Rome Tor Vergata; Case Western Reserve University and other collaborators

Completed

Ablation of Clinical Ventricular Tachycardia Versus Addition of Substrate Ablation on the Long Term Success Rate of VT Ablation (VISTA)

Ventricular Tachycardia

United States
National Institute of Diabetes and Digestive and...
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Effects of Recombinant Human Glutamic Acid Decarboxylase on the Progression of Type 1 Diabetes in New Onset Subjects (TN08)

Type 1 Diabetes Mellitus

United States, Canada
National Institute of Diabetes and Digestive and...
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Oral Insulin for Prevention of Diabetes in Relatives at Risk for Type 1 Diabetes Mellitus (TN07)

Diabetes Mellitus, Type 1

United States, Canada, Italy, Finland, Australia, United Kingdom

Clinical Trials Sponsored by Children's Center for Digestive Health Care

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