Clinical Trials Sponsored by National Eye Institute (NEI)

Total 16187 results

State University of New York College of Optometry
National Eye Institute (NEI); Nova Southeastern University; University of Maryland...

Unknown

Light-deprivation Utilized to Mitigate Amblyopia (LUMA)

Amblyopia

United States
University of California, San Francisco
National Eye Institute (NEI); Emory University; The Carter Center; Amhara Public...

Recruiting

Sanitation, Water, and Instruction in Face-washing for Trachoma I/II (SWIFT I/II)

Trachoma

Ethiopia
Icahn School of Medicine at Mount Sinai
University of California, Los Angeles; National Eye Institute (NEI)

Recruiting

Snapshot Camera for AMD

Age Related Macular Degeneration

United States
Singapore National Eye Centre
National Medical Research Council (NMRC), Singapore; Singapore Eye Research... and other collaborators

Completed

Autologous ex Vivo Conjunctival Epithelial Cell Expansion for Ocular Surface Transplantation

Pterygium | Ocular Surface Disease | Chemical Injury | Stevens Johnson Syndrome

Singapore
New York University Cancer Institute
National Cancer Institute (NCI)

Completed

Thalidomide in Treating Patients With Gynecologic Sarcomas

Sarcoma | Endometrial Cancer

United States
National Eye Institute (NEI)
Bausch & Lomb Incorporated; Eye Bank Association of America; Midwest Eye Banks; Tissue Banks International and other collaborators

Completed

Cornea Donor Study (CDS)

Corneal Disease | Fuch's Dystrophy | Pseudophakic Corneal Edema

United States
Istituto Nazionale per lo Studio e la Cura dei...

Unknown

Docetaxel in Treating Patients With Non-Small Cell Lung Cancer

Lung Cancer

Italy
Singapore Eye Research Institute
National Medical Research Council (NMRC), Singapore

Unknown

The Asia Primary Tube Versus Trab (TVT) Study (TVT)

Glaucoma

Singapore
National Eye Institute (NEI)
National Heart, Lung, and Blood Institute (NHLBI); National Center for Complementary... and other collaborators

Completed

Age-Related Eye Disease Study 2 (AREDS2) (AREDS2)

Age-related Macular Degeneration | Cataract

United States
Istituto Nazionale per lo Studio e la Cura dei...

Unknown

Vinorelbine and/or Gemcitabine in Treating Older Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer

Lung Cancer

Italy
University of New Mexico
National Cancer Institute (NCI)

Completed

Move For Your Health for Older Cancer Survivors

Cancer Survivors

United States
University of New Mexico
National Cancer Institute (NCI)

Active, not recruiting

Remote Assessment of Physical Function

Cancer Survivors

United States
University of New Mexico
National Cancer Institute (NCI)

Completed

Mediators and Moderators of Exercise Behavior Change (COSTRIDE)

Validate STRIDE Exercise Intervention in Sedentary Individuals | Increase Positive Attitudes, Perceived Normative Support, Self-efficacy, and Intentions | Increase Self-reported Physical Activity

United States
Duke University
University of Pennsylvania; Washington University School of Medicine; National... and other collaborators

Completed

Analyzing Retinal Microanatomy in ROP (BabySTEPS)

Macular Edema | Neurodevelopmental Disorders | Retinopathy of Prematurity

United States
The Emmes Company, LLC
National Eye Institute (NEI); University of Wisconsin, Madison; Milton S. Hershey...

Completed

Study of Comparative Treatments for Retinal Vein Occlusion 2 (SCORE2) (SCORE2)

Central Retinal Vein Occlusion

United States
Institut Paoli-Calmettes

Unknown

Gemcitabine With or Without Sorafenib in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer

Pancreatic Cancer

France
University of New Mexico
National Cancer Institute (NCI)

Completed

Biological Therapy Plus Chemotherapy in Treating Patients With Metastatic or Recurrent Kidney Cancer

Kidney Cancer

United States
Institut Paoli-Calmettes

Completed

Fludarabine, Busulfan, and Antilymphocyte Globulin Followed by Donor Stem Cell Transplant in Treating Older Patients With Hematological Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

France
Institut Paoli-Calmettes

Completed

Natural Killer Cells in Older Patients With Acute Myeloid Leukemia

Leukemia

France
Institut Paoli-Calmettes

Completed

Fludarabine, Busulfan, Antithymocyte Globulin, and Donor Stem Cell Transplant in Treating Patients With Multiple Myeloma That Has Not Responded to Treatment

Multiple Myeloma and Plasma Cell Neoplasm

France
Institut Paoli-Calmettes

Completed

Laromustine, Daunorubicin, and Cytarabine in Treating Patients With Acute Myeloid Leukemia

Leukemia

France
Institut Paoli-Calmettes

Unknown

Stem Cell Transplant in Treating Patients With Hematological Cancer or Other Disorders

Lymphoma | Leukemia | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Graft Versus Host Disease

France
University of New Mexico
National Cancer Institute (NCI)

Active, not recruiting

Enhancing Prevention Pathways Toward Tribal Colorectal Health

Colorectal Neoplasm

United States
University of New Mexico
National Cancer Institute (NCI)

Withdrawn

A Novel Magnetic Needle Using Iron Oxide Nanoparticles for the Detection of Leukemia

Leukemia

United States
Institut Català d'Oncologia

Unknown

Study of Information Received About Fertility and Infertility in Patients Who Have Finished Treatment for Cancer

Cancer

Spain
Institut Català d'Oncologia

Unknown

Sunitinib Malate and Exemestane in Treating Postmenopausal Women With Breast Cancer

Breast Cancer

Spain
Institut Paoli-Calmettes

Completed

Vaccine Therapy in Treating Patients With Acute Myeloid Leukemia in Complete Remission

Leukemia

France
Singapore Eye Research Institute
University of Melbourne; Curtin University; Singapore National Eye Centre; Ministry...

Unknown

Living Successfully With Chronic Eye Diseases (ADAPT-LAH)

Glaucoma | Diabetic Retinopathy | Age-related Macular Degeneration | Low Vision | Chronic Diseases

Singapore
National Cancer Institute (NCI)
National Institutes of Health (NIH)

Completed

Defined Green Tea Catechin Extract in Treating Women With Hormone Receptor Negative Stage I-III Breast Cancer

Stage I Breast Cancer | Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Estrogen Receptor-negative Breast Cancer | Progesterone Receptor-negative Breast Cancer

United States
University of California, San Francisco
Northwestern University; National Eye Institute (NEI); Oregon Health and Science... and other collaborators

Completed

Methotrexate and Mycophenolate Mofetil for UVEITIS (FAST)

Uveitis

United States, India, Australia, Mexico, Saudi Arabia
National Cancer Institute (NCI)
Rutgers Cancer Institute of New Jersey

Completed

Study of Bacillus Calmette-Guerin (BCG) Combined With PANVAC Versus BCG Alone in Adults With High Grade Non-Muscle Invasive Bladder Cancer Who Failed At Least 1 Course of BCG

Bladder Cancer

United States
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Completed

Action to Control Cardiovascular Risk in Diabetes (ACCORD) (ACCORD)

Cardiovascular Diseases | Coronary Disease | Hypertension | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Atherosclerosis | Hypercholesterolemia

United States, Canada
National Cancer Institute (NCI)

Not yet recruiting

Venetoclax for the Treatment of Patients With Relapsed Hairy Cell Leukemia

Recurrent Hairy Cell Leukemia | Recurrent Hairy Cell Leukemia Variant
National Cancer Institute (NCI)

Recruiting

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Neuroblastoma | Ganglioneuroblastoma

United States
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal Cancer

Metastatic Colorectal Adenocarcinoma | Refractory Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8

United States
National Cancer Institute (NCI)

Recruiting

Chemotherapy Combined With Immunotherapy vs Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

Stage IV Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Stage IIIC Lung Cancer AJCC v8 | Advanced Lung Non-Small Cell Carcinoma

United States
National Cancer Institute (NCI)

Recruiting

A Study Using a New Drug, Nivolumab, in Combination With Chemotherapy Drugs to Treat a Type of Cancer Called Nasopharyngeal Carcinoma (NPC)

Stage IV Nasopharyngeal Carcinoma AJCC v8 | Stage II Nasopharyngeal Carcinoma AJCC v8 | Stage III Nasopharyngeal Carcinoma AJCC v8

United States
National Cancer Institute (NCI)

Not yet recruiting

Testing RG1-VLP Vaccine to Prevent HPV-related Cancers

Human Papillomavirus-Related Carcinoma

United States, Austria
National Cancer Institute (NCI)

Recruiting

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder for Bladder Cancer Treatment, MODERN Study

Stage III Bladder Urothelial Carcinoma AJCC v6 and v7 | Stage IV Bladder Urothelial Carcinoma AJCC v7 | Stage II Bladder Urothelial Carcinoma AJCC v6 and v7 | Muscle Invasive Bladder Urothelial Carcinoma

United States
National Cancer Institute (NCI)

Recruiting

Testing the Combination of Two Anticancer Drugs M1774 (Tuvusertib) and Avelumab to Evaluate Their Safety and Effectiveness in Treating Merkel Cell Skin Cancer, MATRiX Trial

Metastatic Merkel Cell Carcinoma | Refractory Merkel Cell Carcinoma | Locally Advanced Merkel Cell Carcinoma | Unresectable Merkel Cell Carcinoma | Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8 | Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8

United States
National Cancer Institute (NCI)

Recruiting

Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

Metastatic Melanoma | Unresectable Melanoma | Clinical Stage III Cutaneous Melanoma AJCC v8 | Metastatic Merkel Cell Carcinoma | Metastatic Skin Squamous Cell Carcinoma | Clinical Stage IV Cutaneous Melanoma AJCC v8 | Metastatic Basal Cell Carcinoma | Unresectable Merkel Cell Carcinoma | Unresectable... and other conditions

United States
National Cancer Institute (NCI)

Recruiting

Testing the Addition of an Anti-cancer Drug, SNDX-5613, to the Standard Chemotherapy Treatment (Daunorubicin and Cytarabine) for Newly Diagnosed Patients With Acute Myeloid Leukemia That Has Changes in NPM1 or MLL/KMT2A Gene

Acute Myeloid Leukemia With KMT2A Rearrangement | Acute Myeloid Leukemia With NPM1 Mutation

United States
National Cancer Institute (NCI)

Recruiting

Testing the Anti-cancer Drug Erdafitinib for Brain Cancers That Have Returned or Progressed Following Treatment

Recurrent WHO Grade 2 Glioma | Recurrent Glioblastoma, IDH-Wildtype | Recurrent WHO Grade 3 Glioma

United States
National Cancer Institute (NCI)

Recruiting

A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis

Recurrent Langerhans Cell Histiocytosis | Refractory Langerhans Cell Histiocytosis

United States, Canada
National Cancer Institute (NCI)

Recruiting

Testing the Efficacy of Topical Calcipotriene Plus 5-Fluorouracil Combination to Activate the Immune System Against Precancerous Skin Lesions in Organ Transplant Recipients

Actinic Keratosis

United States
National Cancer Institute (NCI)

Recruiting

Testing How the Body Responds to the Drug CBX-12 in Patients With Advanced Solid Cancers

Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
National Cancer Institute (NCI)

Recruiting

Testing the Use of AMG 510 (Sotorasib) and Panitumumab as a Targeted Treatment for KRAS G12C Mutant Solid Tumor Cancers (A ComboMATCH Treatment Trial)

Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
National Cancer Institute (NCI)

Recruiting

Testing the Safety of the Anti-cancer Drugs Tazemetostat and Belinostat in Patients With Lymphomas That Have Resisted Treatment

Refractory B-Cell Non-Hodgkin Lymphoma | Refractory T-Cell Non-Hodgkin Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Transformed Non-Hodgkin Lymphoma | Recurrent Non-Hodgkin Lymphoma | Refractory Non-Hodgkin Lymphoma | Recurrent T-Cell Non-Hodgkin Lymphoma | Recurrent Primary Cutaneous... and other conditions

United States
National Cancer Institute (NCI)

Recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Anatomic Stage III Breast Cancer AJCC v8 | Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Anatomic Stage IV Breast Cancer AJCC v8 | Advanced Malignant Solid Neoplasm | Locally Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid... and other conditions

United States, Puerto Rico
National Cancer Institute (NCI)

Not yet recruiting

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

Acute Myeloid Leukemia

Clinical Trials Sponsored by National Eye Institute (NEI)

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