Clinical Trials Sponsored by Semafore Pharmaceuticals

Total 19663 results

Karos Pharmaceuticals

Completed

Single and Multiple Ascending Doses Clinical Pharmacology Study With KAR5585

Pulmonary Arterial Hypertension

United States
Merrimack Pharmaceuticals

Completed

A Study of MM-121 Combination Therapy in Patients With Advanced Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

Spain, Taiwan, United States, Canada, Korea, Republic of, Germany
Jazz Pharmaceuticals

Withdrawn

Phase 3, 28-week, Randomized, Double-blind, Placebo-controlled Safety and Efficacy Study of Nabiximols as an add-on Therapy in Subjects With Spasticity Due to Multiple Sclerosis.

Multiple Sclerosis | Spasticity
Progen Pharmaceuticals

Completed

Study of CGC-11047 When Used in Individual Combinations With 1) Gemcitabine or 2) Docetaxel or 3) Bevacizumab or 4) Erlotinib or 5) Cisplatin or 6) 5-Flurouracil or 7) Sunitinib in Patients With Advanced Solid Tumors or Lymphoma

Cancer

United States
Avanir Pharmaceuticals

Completed

Safety/Efficacy of AVP-923 in the Treatment of Emotional Lability (Uncontrolled Crying & Laughing) in Patients With ALS

Amyotrophic Lateral Sclerosis

United States
Alexion Pharmaceuticals

Completed

Evaluation of Blood Brain Barrier Integrity and Structural Abnormalities in MPS IIIB Patients Using Multimodal Magnetic Resonance Imaging

MPS IIIB (Sanfilippo B Syndrome)

United Kingdom
Alexion Pharmaceuticals

No longer available

An Expanded Access Protocol for Sebelipase Alfa for Patients With Lysosomal Acid Lipase Deficiency

Lysosomal Acid Lipase Deficiency
TetraLogic Pharmaceuticals

Completed

Dose Escalation, Combination Chemotherapy Safety Study of Birinapant (TL32711), in Subjects With Advanced or Metastatic Solid Tumors

Cancer

United States
Regeneron Pharmaceuticals

Completed

Study to Assess the Safety and Tolerability of Single Doses of REGN1500

Hypertriglyceridemia

United States
Regeneron Pharmaceuticals

Completed

Study of Fasinumab (REGN475) in Healthy Japanese and Caucasian Subjects

Healthy Volunteers

United States
Regeneron Pharmaceuticals

Terminated

Study of REGN1193 in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States
Merrimack Pharmaceuticals

Completed

Trial of Exemestane +/- MM-121 in Postmenopausal Women With Locally Advanced or Metastatic Estrogen Receptor Positive and/or Progesterone Receptor Positive Her2 Negative Breast Cancer

Her2 Negative Breast Cancer Patients

United States, Spain, Canada, Germany, Russian Federation
Concert Pharmaceuticals

Completed

Food Effect Study of CTP-656 in Healthy Male Volunteers

Healthy

Australia
SymBio Pharmaceuticals

Completed

Efficacy and Safety Study of SyB L-0501 in Combination With Rituximab in Patients With Untreated, Low-grade B Cell Non-Hodgkin's Lymphoma and Mantle Cell Lymphoma

Low-grade B Cell Non-Hodgkin's Lymphoma | Mantle Cell Lymphoma Where Hematopoietic Stem Cell Transplantation is Not Indicated

Japan
Cumberland Pharmaceuticals

Completed

Efficacy of Intravenous Ibuprofen Compared to Intravenous Ketorolac for Pain Control Following Arthroscopic Knee Surgery

Pain

United States
Lexicon Pharmaceuticals

Unknown

Oral Contraceptive DDI Study

Healthy

United States
BioCryst Pharmaceuticals

Terminated

Open-label, Long-term Safety Study of Avoralstat in Subjects With Hereditary Angioedema (OPuS-4)

Hereditary Angioedema | HAE

France, Belgium
TetraLogic Pharmaceuticals

Completed

Study of Birinapant in Combination With Conatumumab in Subjects With Relapsed Ovarian Cancer

Relapsed Epithelial Ovarian Cancer | Relapsed Primary Peritoneal Cancer | Relapsed Fallopian Tube Cancer

United States
Elan Pharmaceuticals

Completed

Ziconotide Effectiveness and Safety Trial in Patients With Chronic Severe Pain

Pain

United States
Elan Pharmaceuticals

Terminated

A Safety and Efficacy Study of ELND002 in Patients With Relapsing Forms of Multiple Sclerosis

Multiple Sclerosis

United States, Canada
Elan Pharmaceuticals

Completed

A Study to Measure the Safety and Effectiveness of Zonisamide in Subjects With Migraine Headache

Migraine Headache

United States
Elan Pharmaceuticals

Completed

Prialt (Ziconotide) In Severe Chronic Pain

Pain

United States
Elan Pharmaceuticals

Completed

Comparison of Safety and Efficacy of Tizanidine Hydrochloride Capsules Versus Zanaflex® (Tizanidine Hydrochloride Tablets) Taken While in the Fed State (Just After a Meal) and in the Fasted State (Before a Meal) in Patients With Moderate to Severe Spasticity.

Stroke | Multiple Sclerosis | Muscle Spasticity | Spinal Cord Injury

United States
Elan Pharmaceuticals

Terminated

Open-label Adjunctive Zonisamide for Bipolar Disorder

Bipolar Disorders
Primus Pharmaceuticals

Completed

Study of Flavocoxid (Limbrel) vs Naproxen in Subjects With Mod-Severe Osteoarthritis of the Knee

Osteoarthritis

United States
Primus Pharmaceuticals

Completed

Safety, Efficacy and Acceptability of Flavocoxid (Limbrel)A Pilot Study

Osteoarthritis

United States
Santhera Pharmaceuticals

Completed

Phase III Study of Idebenone in Duchenne Muscular Dystrophy (DMD) (DELOS)

Muscular Dystrophy, Duchenne | Ambulatory Care

United States, Spain, Austria, Belgium, France, Germany, Italy, Netherlands, Sweden, Switzerland
Veloxis Pharmaceuticals

Completed

Switching Study of Kidney Transplant Patients With Tremor to LCP-Tacro (STRATO) (STRATO)

Renal Failure | Tremors

United States
Regeneron Pharmaceuticals

Completed

Study to Assess the Safety and Tolerability of Multiple Ascending Doses of REGN1500

Metabolic Disorders

United States
Sideris Pharmaceuticals

Terminated

Safety and Pharmacokinetic Study of Escalating Doses of SP-420, an Iron Chelator, in Patients With β-Thalassemia

Iron Overload | Beta-Thalassemia

United States, Canada, Lebanon, Thailand, Turkey
Concert Pharmaceuticals

Completed

Study to Evaluate Safety, Tolerability and PK of C-10355 and C-10358 in Healthy Subjects

Healthy

Australia
Ferring Pharmaceuticals

Completed

REgistry of MisOprostol 200 µg Vaginal dElivery System (REMOVE)

Induction of Labour

Netherlands
Ferring Pharmaceuticals

Completed

Study to Assess the Efficacy and Safety of Three Dosage Strengths of Pulsatile GnRH Delivered From a Iontophoretic Patch Compared to Oral Treatment With Clomiphene or Placebo in Infertile Females

Infertility

United States
Ferring Pharmaceuticals

Completed

A Study Into the Effectivity and Safety of Firmagon, Prescribed for Treatment of Patients With Advanced Prostate Cancer (FAST-NL)

Prostate Cancer

Netherlands
Arrowhead Pharmaceuticals

Withdrawn

Study of ARC-520 in Patient With Chronic Hepatitis B Virus

Chronic Hepatitis B

Australia
Anthera Pharmaceuticals

Withdrawn

CHABLIS-SC2: A Study of the Efficacy and Safety of Subcutaneous Blisibimod in Subjects With Systemic Lupus Erythematosus With or Without Nephritis

Systemic Lupus Erythematosus
Anthera Pharmaceuticals

Withdrawn

BIANCA-SC: A Study of the Efficacy, Safety, and Tolerability of Blisibimod in Addition to Methotrexate During Induction of Remission in Subjects With ANCA-Associated Small Vessel Vasculitis (BIANCA-SC)

Microscopic Polyangiitis | Granulomatosis With Polyangiitis
Anthera Pharmaceuticals

Withdrawn

BRILLIANT-SC: A Study of the Efficacy and Safety of Blisibimod Administration in Subjects With IgA Nephropathy

IgA Nephropathy
Alexion Pharmaceuticals

Completed

Open Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-Resistant aHUS (aHUS)

Atypical Hemolytic Uremic Syndrome

France, United States, Austria, Germany, United Kingdom
Alexion Pharmaceuticals

Completed

Open Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-sensitive Atypical Hemolytic Uremic Syndrome (aHUS) (aHUS)

Atypical Hemolytic Uremic Syndrome

Canada, United Kingdom, France, Germany, Sweden, Netherlands, Italy
Ferring Pharmaceuticals

Completed

One Month Degarelix/Comparator Treatment for Prostate Cancer in Chinese Population (PANDA)

Prostate Cancer

China
Vanda Pharmaceuticals

Completed

Melatonin Agonist Effects of Tasimelteon Versus Placebo in Patients With Major Depressive Disorder (MAGELLAN)

Major Depressive Disorder

United States
Endo Pharmaceuticals

Completed

CORRECT: COmmunity RegistRy Study Evaluating Dupuytren's Contracture Treatment (CORRECT)

Dupuytren's Contracture

United States
Endo Pharmaceuticals

Completed

Longterm Observational Study in Subjects Treated With AA4500 in AUX-CC-854, 856, 857, 858 & 859

Dupuytren's Disease

United States, Denmark, Australia, Finland, Sweden, United Kingdom
Ferring Pharmaceuticals

Completed

Barusiban Subcutaneously for Reducing Implantation Failure Due to Uterine Contractions (BASIC)

Infertility

Belgium, Spain, Australia, Canada, Czech Republic, Poland
Ferring Pharmaceuticals

Completed

A Trial of Degarelix in Men With Lower Urinary Tract Symptoms (LUTS) Associated With Benign Prostatic Hyperplasia (BPH) (DELUTS)

Lower Urinary Tract Symptoms (LUTS)

United States, Canada, Belgium, Czech Republic, Italy, Poland
Cumberland Pharmaceuticals

Completed

2 Regimens of Lactulose for Colonoscopy Preparation in Adults

Colonoscopy Preparation

United States
Concert Pharmaceuticals

Completed

A Safety and Tolerability Study of CTP-730 in Healthy Volunteers

Healthy

Australia
Concert Pharmaceuticals

Completed

A Phase 1, Single Dose Study of JZP-386 to Evaluate Safety, Pharmacokinetics and Pharmacodynamics

Narcolepsy, Excessive Daytime Sleepiness

United Kingdom
Ferring Pharmaceuticals

Completed

Efficacy and Safety of XP12B in Women With Menorrhagia

Menorrhagia | Heavy Menstrual Bleeding

United States

3

Subscribe