Clinical Trials Sponsored by UNC Lineberger Comprehensive Cancer Center

Total 5675 results

Case Comprehensive Cancer Center

Completed

Music Therapy and Hematopoietic Stem Cell Transplant

Hematopoietic Stem Cell Transplant

United States
Case Comprehensive Cancer Center

Completed

A Pilot Study of Structured Palliative Care for Patients Enrolled on Phase I Clinical Trials

Cancer

United States
Case Comprehensive Cancer Center

Terminated

Lapatinib With Carboplatin and Paclitaxel in Esophagus and Gastroesophageal Junction (GEJ)

Adenocarcinoma of the Gastroesophageal Junction | Adenocarcinoma of the Esophagus

United States
Case Comprehensive Cancer Center

Completed

Differentiation Therapy With Decitabine in Treating Patients With Myelodysplastic Syndrome

Myelodysplastic Syndromes | Thrombocytopenia | Chronic Myelomonocytic Leukemia | de Novo Myelodysplastic Syndromes | Refractory Anemia | Refractory Anemia With Excess Blasts | Refractory Cytopenia With Multilineage Dysplasia | Refractory Anemia With Ringed Sideroblasts

United States
Case Comprehensive Cancer Center

Completed

Sunitinib Malate in Treating Patients With Previously Untreated Metastatic Kidney Cancer

Clear Cell Renal Cell Carcinoma | Stage IV Renal Cell Cancer

United States
Case Comprehensive Cancer Center

Completed

Pazopanib Hydrochloride Before Surgery in Treating Patients With Kidney Cancer

Clear Cell Renal Cell Carcinoma | Stage III Renal Cell Cancer | Stage I Renal Cell Cancer | Stage II Renal Cell Cancer

United States
Case Comprehensive Cancer Center

Terminated

Radiosurgery Plus Bevacizumab in Glioblastoma

Glioblastoma | Brain Tumor | Gliosarcoma

United States
Case Comprehensive Cancer Center

Completed

PSA TOOL for Prostate Cancer Screening Discussions

Prostate Cancer

United States
Case Comprehensive Cancer Center

Withdrawn

Optimization of Ureterolysis During Hysterectomy

Hysterectomy
Case Comprehensive Cancer Center

Completed

Enhanced Recovery After Surgery: A RCT of Perioperative Management of Gynecologic Patients

Laparotomy | Gynecologic Diseases

United States
Case Comprehensive Cancer Center

Withdrawn

A Trial of CDX-1401 in Combination With Poly-ICLC and Pembrolizumab, in Previously Treated Advanced Solid Tumor Patients

Small Cell Lung Cancer | Non Small Cell Lung Cancer | Mesothelioma | Urothelial Cancer | Malignant Melanoma | Advanced Triple Negative Breast Cancer
Jonsson Comprehensive Cancer Center

Withdrawn

Compassionate Single Subject Use of FG-3019 (FibroGen) in Locally Advanced, Unresectable Pancreatic Cancer

Pancreatic Cancer
Jonsson Comprehensive Cancer Center

Completed

Aromatase Inhibitor-Associated Musculoskeletal Symptoms in Non-Metastatic, Post Menopausal Breast Cancer Patients

Breast Cancer

United States
Jonsson Comprehensive Cancer Center

Completed

Breast Cancer Screening Intervention

Breast Cancer
Jonsson Comprehensive Cancer Center

Completed

A Study Of the Effectiveness Of Pomegranate Pills in Men With Prostate Cancer Before Prostatectomy

Prostate Cancer

United States
Case Comprehensive Cancer Center

Completed

Bortezomib, Mitoxantrone, Etoposide, and Cytarabine in Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute... and other conditions

United States
Case Comprehensive Cancer Center

Terminated

Biofeedback Training in Patients With Advanced Lung Cancer - A Pilot Study

Advanced (Stage IV) Non-small Cell Lung Cancer (NSCLC)

United States
Case Comprehensive Cancer Center

Terminated

Ritonavir and Lopinavir in Treating Patients With Progressive or Recurrent High-Grade Glioma

Glioblastoma | Brain Tumor | Gliosarcoma | Anaplastic Astrocytoma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Giant Cell Glioblastoma | Mixed Glioma | Brain Stem Glioma

United States
Case Comprehensive Cancer Center

Completed

Cryotherapy for Barrett's Esophagus and Early Esophageal Cancers

Esophageal Cancer | Barretts Esophagus

United States
Jonsson Comprehensive Cancer Center

Completed

Combination Chemotherapy With or Without Amifostine in Treating Patients With Recurrent or Refractory Non-Hodgkin's Lymphoma or Hodgkin's Disease Undergoing Stem Cell Transplantation

Lymphoma

United States
Jonsson Comprehensive Cancer Center

Completed

The Biodistribution of 1-[2 Deoxy-2, -18 Fluroarabinfuranosyl]Cytosine [18FAC] in Healthy Subjects and Patients With Cancer, Autoimmune/Inflammatory Diseases

Inflammation | Cancer

United States
Case Comprehensive Cancer Center

Withdrawn

Stereotactic Body Radiation Therapy in Liver Cancer That Cannot be Removed by Surgery or Transplant

Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Adult Primary Hepatocellular Carcinoma
Case Comprehensive Cancer Center

Withdrawn

Breast-Conserving Surgery Followed by Radiation Therapy With MRI-Detected Stage I or Stage II Breast Cancer

Stage I Breast Cancer | HER2-positive Breast Cancer | Male Breast Cancer | Stage II Breast Cancer | Estrogen Receptor-negative Breast Cancer | Estrogen Receptor-positive Breast Cancer | Progesterone Receptor-negative Breast Cancer | Progesterone Receptor-positive Breast Cancer | HER2-negative Breast... and other conditions

United States
Case Comprehensive Cancer Center

Completed

High-Dose Busulfan and High-Dose Cyclophosphamide Followed By Donor Bone Marrow Transplant in Treating Patients With Leukemia, Myelodysplastic Syndrome, Multiple Myeloma, or Recurrent Hodgkin or Non-Hodgkin Lymphoma

Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent... and other conditions

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI); National Institute of Allergy and Infectious...

Completed

The Families Addressing Cancer Together Intervention for Parents With Cancer (FACT)

Neoplasms | Cancer | Communication | Parent-Child Relations | Parenting | Parents

United States
Jonsson Comprehensive Cancer Center
Genentech, Inc.

Completed

Bevacizumab and Temozolomide in Treating Older Patients With Newly-Diagnosed Glioblastoma Multiforme or Gliosarcoma

Glioblastoma | Gliosarcoma | Giant Cell Glioblastoma

United States
Jonsson Comprehensive Cancer Center

Recruiting

Study of Magnetic Resonance Image and Computed Tomography-Guided Stereotactic Body Radiation Therapy for Abdominopelvic Sarcomas (MARS Trial)

Abdominopelvic Sarcomas

United States
Case Comprehensive Cancer Center

Not yet recruiting

Developing Inclusive Support and Intervention for Spanish-speaking Latiné Prostate Cancer Survivors

Prostate Cancer

United States
Case Comprehensive Cancer Center

Not yet recruiting

Brain MRF in Children, Adolescents and Young Adults With Acute Leukemia

Acute Leukemia | Acute Lymphoblastic Leukemia, Pediatric | Myeloproliferative Neoplasm | Acute Myeloid Leukemia in Children

United States
Case Comprehensive Cancer Center

Not yet recruiting

Reiki Therapy to Improve Key Symptoms in Integrative Oncology Clinic (REIKI)

Cancer Pain | Oncology Pain

United States
Case Comprehensive Cancer Center

Not yet recruiting

Abbreviated MBCT for Depression in Older African American/Black Breast Cancer Survivors

Breast Cancer | Breast Cancer Stage I | Breast Cancer Stage II | Breast Cancer Female | Breast Cancer Stage III | Moderate Depression | Mild Depression

United States
Jonsson Comprehensive Cancer Center

Not yet recruiting

Fluoxetine for the Modification of Colorectal Tumor Immune Cells Before Surgery in Patients With Colorectal Cancer

Colorectal Adenocarcinoma

United States
Jonsson Comprehensive Cancer Center

Not yet recruiting

Phase 2 Randomized Trial of Flexible Dosing Schedule of 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer (FLEX-MRT)

Prostate Carcinoma | Stage IVB Prostate Cancer American Joint Committee on Cancer (AJCC) v8

United States
Jonsson Comprehensive Cancer Center

Recruiting

An Organoid-based Functional Precision Medicine Trial in Osteosarcoma (PREMOST)

Osteosarcoma

United States
Jonsson Comprehensive Cancer Center

Recruiting

Utilizing Advocates and Supporters to Increase Lung Cancer Screening Rates in Eligible Participants

Breast Carcinoma | Lung Carcinoma

United States
Jonsson Comprehensive Cancer Center

Recruiting

Red Blood Cell Transfusion Thresholds for Improved Quality of Life for Patients Undergoing a Pancreatectomy for Pancreatic Cancer

Resectable Pancreatic Carcinoma

United States
Case Comprehensive Cancer Center

Recruiting

eXtended Antibiotic Prophylaxis for Intermediate- and High-risk Glands After Pancreatoduodenectomy to Reduce CR-POPF

Pancreatic Fistula

United States
Case Comprehensive Cancer Center

Recruiting

Methimazole in Patients With Progressive Glioblastoma

Glioma | Glioblastoma

United States
Case Comprehensive Cancer Center

Not yet recruiting

Metabolic Impact of Prospective Controlled Mediterranean Type Diets on Prostate Cancer

Prostate Cancer
Case Comprehensive Cancer Center

Recruiting

Cleveland African American Prostate Cancer Project

Prostate Cancer

United States
Case Comprehensive Cancer Center

Recruiting

Disulfiram With Copper Gluconate and Liposomal Doxorubicin in Treatment-Refractory Sarcomas

Relapsed Sarcomas

United States
Case Comprehensive Cancer Center

Recruiting

Detection of Barrett s Esophagus in Patients Without GERD Symptoms

Barrett's Esophagus

United States
Case Comprehensive Cancer Center

Recruiting

Low-Dose-Rate Brachytherapy Combined With Immune Checkpoint Inhibition in Cancer

Renal Cell Cancer | Urothelial Cancer of Renal Pelvis | Cutaneous Malignant Melanoma

United States
Case Comprehensive Cancer Center

Recruiting

Exercise Therapy and Radiation Therapy (EXERT) for Metastatic Prostate Cancer

Metastatic Prostate Cancer

United States
Case Comprehensive Cancer Center

Recruiting

Teach-back Method on Patient Satisfaction and Adherence to Wound Care Regimen

Keratinocyte Carcinoma

United States
Case Comprehensive Cancer Center

Recruiting

Evaluating the Effectiveness of an Individualized Nutrition and Physical Activity Counseling Program

Breast Cancer

United States
Case Comprehensive Cancer Center

Not yet recruiting

Study to Investigate Efficacy of a Novel Probiotic on the Bacteriome and Mycobiome of Breast Cancer

Breast Cancer

United States
Case Comprehensive Cancer Center

Recruiting

Building Family Caregiver Skills Using a Simulation-Based Intervention for Care of Cancer Patients

Cancer

United States
Case Comprehensive Cancer Center

Recruiting

CPX-351 Therapy for MDS After Hypomethylating Agent Failure

Myelodysplastic Syndrome (MDS)

United States
Case Comprehensive Cancer Center

Recruiting

Educate, Assess Risk and Overcoming Barriers to Colorectal Screening Among African Americans

Colorectal Cancer

United States

Clinical Trials Sponsored by UNC Lineberger Comprehensive Cancer Center

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