Search clinical trials for: Intravitreal (IVT)

Total 1020 results

Xinhua Hospital, Shanghai Jiao Tong University...

Completed

Serum Vascular Endothelial Growth Factor in Infants With Intravitreal Ranibizumab

Infant, Premature, Diseases

China
Bayer

Completed

Investigation of the Change of Vision-related Quality of Life in Subjects Treated With Aflibercept According to EU Label for DME. (AQUA)

Macular Edema

Spain, Canada, Switzerland, Portugal, Austria, Poland, Slovakia, United Kingdom, France, Czechia, Germany, Hungary, Italy, Lithuania
J. Fernando Arevalo, MD FACS
Pan American Collaborative Retina Study Group

Completed

Pre-Operative Intravitreal Bevacizumab for Tractional Retinal Detachment Secondary to Proliferative Diabetic Retinopathy

Tractional Retinal Detachment Secondary to Proliferative Diabetic Retinopathy

Saudi Arabia
David M. Brown, M.D.
Genentech, Inc.

Completed

Efficacy & Safety Trial of Intravitreal Injections Combined With PRP for CSME Secondary to Diabetes Mellitus (DAVE) (DAVE)

Diabetic Macular Edema

United States
Regeneron Pharmaceuticals
Bayer

Completed

Anti-vasculaR Endothelial Growth Factor plUs Anti-angiopoietin 2 in Fixed comBination therapY: Evaluation for the Treatment of Diabetic Macular Edema (RUBY)

Diabetic Macular Edema

United States
Wills Eye
Mid Atlantic Retina

Terminated

Intravitreal Dexamethasone Implant for Persistent Macular Thickening and Edema After Vitrectomy for Epiretinal Membrane (DEMO)

Macular Edema | Epiretinal Membrane | Vitrectomy

United States
Jaeb Center for Health Research
National Eye Institute (NEI); Genentech, Inc.; Allergan

Completed

Phase II Combination Steroid and Anti-VEGF for Persistent DME

Diabetic Macular Edema

United States
Retinal Consultants of Arizona
Ophthotech Corporation

Completed

An Open-Label Investigator Sponsored Trial to Investigate the Safety, Tolerability and Development of Subfoveal Fibrosis By Intravitreal Administration of Altering Regimens of Fovista and Anti-VEGF Therapy in Subjects With Neovascular Age-Related Macular Degeneration

Neovascular Age-Related Macular Degeneration

United States
Hospital Hietzing

Completed

Intravitreal Anti-vascular Endothelial Growth Factor Administration and Its Influence on Vitreomacular Interface- and Retinal Morphology in Eyes With Neovascular Age-related Macular Degeneration

Vitreomacular Interface
Soll Eye
Genentech, Inc.

Completed

Acute Pseudophakic Cystoid Macular Edema Treatment Trial: Intravitreal Ranibizumab Versus Triamcinolone Acetonide

CYSTOID MACULAR EDEMA

United States
Vitreous -Retina- Macula Consultants of New York

Completed

To Evaluate The Role of Intravitreal Aflibercept Injection (2.0 mg) in the Management of Previously Treated Patients With Exudative AMD

AMD (With Persistent or Recurrent Fluid Despite Monthly Intravitreal Anti-VEGF Therapy)

United States
Shinshu University

Completed

Combination Treatment of Intravitreal Ranibizumab, Focal/Grid Laser and Panretinal Photocoagulation in Patients With Diabetic Macula Edema

Diabetic Macula Edema

Japan
Samsung Medical Center
Bayer; Seoul National University Bundang Hospital; Kim's Eye Hospital

Completed

Efficacy and Safety of Intravitreal Vascular Endothelial Growth Factor Trap-eye in Patients With Polyploidal Choroidal Vasculopathy

Polypoidal Choroidal Vasculopathy Without Active Polyp

Korea, Republic of
Retina Research Institute, LLC

Completed

Intravitreal Aflibercept Injection (IAI) for Presumed Ocular Histoplasmosis Syndrome

Choroidal Neovascularization | Presumed Ocular Histoplasmosis

United States
Federal University of São Paulo
Novartis

Withdrawn

Retinal Ganglion Cell Function After Intravitreous Ranibizumab in Patients With Diabetic Macular Edema

Diabetic Macular Edema

Brazil
Allergan

Completed

Safety and Efficacy of Brimonidine Intravitreal Implant in Patients With Geographic Atrophy Due to Age-related Macular Degeneration (AMD)

Macular Degeneration

Korea, Republic of, Australia, Portugal, Germany, United States, Philippines, Italy
Centre Hospitalier Universitaire Dijon

Completed

Endophthalmitis After Intravitreal Injection of Antiangiogenic Agents or Corticosteroids, a Cohort Study of the French Population of Patients Who Received Injections Over 9 Years (ENIVAC)

Intravitreal Injection
Shanghai Zhongshan Hospital

Unknown

The Effect of Rifaximin on Portal Vein Thrombosis (ERPVT)

Cirrhosis | Portal Vein Thrombosis

China
Wolfson Medical Center

Completed

Reduction of Post Intravitreal Injection Bleeding and Pain by Ice

Pain

Israel
Shahid Beheshti University of Medical Sciences

Unknown

Comparison of Treatment Response to Intravitreal Injection of Combined Propranolol and Bevacizumab Versus Bevacizumab Monotherapy in Patients With Wet Age Related Macular Degeneration :A Clinical Trial

Age Related Macular Degeneration

Iran, Islamic Republic of
National Institutes of Health Clinical Center (CC)
National Eye Institute (NEI)

Terminated

Microplasmin Intravitreal Administration in Participants With Uveitic Macular Edema (MIME)

Uveitis

United States
King's College Hospital NHS Trust
Novartis

Completed

Preoperative Intravitreal Ranibizumab for Persistent Diabetic Vitreous Haemorrhage:

Diabetes Complications

United Kingdom
Aier School of Ophthalmology, Central South University

Completed

High-dose Intravitreal Injection of Ganciclovir for the Treatment of CMVR in HIV-negative Patients

Uveitis, Posterior | Infection Viral
Changhua Christian Hospital

Completed

Real World Outcomes of Intravitreal Anti-vascular Endothelial Growth Factors for Neovascular Age Related Macular Degeneration in Taiwan (OIVAEGFFAMDIT)

AMD

Taiwan
Indonesia University
Bayer

Completed

Early Anatomical, Physiological, and Clinical Changes in Diabetic Macular Edema After Intravitreal Aflibercept Injection

Diabetic Retinopathy | Diabetic Macular Edema | Clinically Significant Macular Edema

Indonesia
The Emmes Company, LLC
National Eye Institute (NEI); Allergan

Completed

The Standard Care vs. COrticosteroid for REtinal Vein Occlusion (SCORE) Study (SCORE)

Retinal Vein Occlusion | Macular Edema, Cystoid

United States
MidAtlantic Retina

Unknown

Comfort and Antimicrobial Efficacy of Chlorhexidine vs Betadine for Intravitreal Injections

Age-related Macular Degeneration | Retina Vein Occlusion | Diabetic Vascular Diseases | Proliferative Retinopathy

United States
Sun Yat-sen University

Unknown

Safety and Effectiveness of Intravitreal Conbercept for Exudative Circumscribed Choroidal Haemangioma

Circumscribed Choroidal Haemangioma

China
Università degli Studi dell'Insubria

Completed

Dexamethasone Intravitreal Implant in Retinal Vein Occlusion

Macular Edema, Cystoid
Southeast Clinical Research Associates, LLC
Regeneron Pharmaceuticals

Withdrawn

Intravitreal Alfibercept for Center Involved DME Previously Managed With Intravitreal Ranibizumab

Diabetic Macular Edema

United States
Shahid Beheshti University of Medical Sciences

Unknown

Comparison of Therapeutic Effects Between Intravitreal Injection of Bevacizumab With Intravitreal Injection of Bevacizumab and Targeted Laser Photocoagulation of Non Perfused Areas of Retina in Patients With Acute Retinal Vein Occlusion (bevacizumab)

Retinal Vein Occlusion With Macular Edema

Iran, Islamic Republic of
Second Affiliated Hospital of Xi'an Jiaotong University

Completed

The Effect of Conbercept Injection Through Different Routes for Neovascular Glaucoma

Neovascular Glaucoma

China
Association for Innovation and Biomedical Research...
European Vision Institute Clinical Research Network

Completed

Retrospective Trial on the Efficacy and Safety of Intravitreal Ozurdex in Patients With Diabetic Macular Edema. (ARTES)

Diabetic Macular Edema

Spain, Portugal, Finland, France, Israel, Italy, Sweden, United Kingdom
Association for Innovation and Biomedical Research...
European Vision Institute Clinical Research Network

Completed

Prospective, Randomized, Multicentre, Open-label, Phase II / III Study to Assess Efficacy and Safety of Ranibizumab 0.5 mg Intravitreal Injections Plus Panretinal Photocoagulation (PRP) Versus PRP in Monotherapy in the Treatment of Subjects With High Risk Proliferative Diabetic Retinopathy. (PROTEUS)

High Risk Proliferative Diabetic Retinopathy

Portugal, Italy, United Kingdom, France
University Hospital of Patras

Completed

Blood Coagulation Parameters in Patients Receiving Intravitreal Aflibercept for Age-related Macular Degeneration

Neovascular Age-related Macular Degeneration

Greece
Vitreous -Retina- Macula Consultants of New York
Genentech, Inc.

Completed

A Pilot Study to Evaluate the Role of High-dose Ranibizumab (2.0mg) in the Management of AMD in Patients With Persistent/Recurrent Macular Fluid Less Than 30 Days Following Treatment With Intravitreal Anti-VEGF Therapy (the LAST Study) (LAST)

Age Related Macular Degeneration

United States
MidAtlantic Retina
Regeneron Pharmaceuticals

Completed

Repeated Eye Injections of Aflibercept for Treatment of Wet Age Related Macular Degeneration (ATLAS)

Age-Related Macular Degeneration | Macular Degeneration

United States
University of Toronto
Dr. Efrem Mandelcorn

Completed

Pre-Administration of Brimonidine in Intravitreal Anti-VEGF Therapy

Post-Injection Intraocular Pressure Spikes
Unity Health Toronto

Terminated

Intravitreal Aflibercept in Wet Age Related Macular Degeneration Patients With an Incomplete Response to Routine Ranibizumab Injections (SHIFT-2)

Age Related Macular Degeneration

Canada
Tennessee Retina
Regeneron Pharmaceuticals

Unknown

Two-week Retreatment Interval Study for Treated Age-related Macular Degeneration Refractory to Monthly Aflibercept (TRISTAR)

Neovascular Age-related Macular Degeneration

United States
Marsden Eye Specialists

Completed

To Evaluate the Comparative Efficacy of Lucentis (Ranibizumab) 0.5mg Intravitreal Injection in Patients With Diabetic Macular Oedema (DME) With Well Controlled and Poorly Controlled Diabetes Mellitus (CONTROL)

Diabetic Macular Oedema

Australia
Pfizer

Completed

A Study to Assess Immune Response Following Zoster Vaccination to Subjects With Rheumatoid Arthritis Receiving Tofacitinib or Placebo With Background Methotrexate

Rheumatoid Arthritis

United States
University Hospital of Patras

Completed

Comparison of the Efficacy of Nepafenac 0.1% and Nepafenac 0.3 % on Pain Associated With Intravitreal Injections

Pain

Greece
Nune Eye Hospital, Seoul, Korea

Unknown

The Effects of Intravitreal Ozurdex Implant in DME

Diabetic Macular Edema

Korea, Republic of
Federal University of São Paulo

Completed

Efficacy Study of Triamcinolone Associated With Nepafenac for Treatment of Diabetic Macular Edema (NEVANAC)

Diabetic Macular Edema

Brazil
Kagawa University
Novartis Pharmaceuticals

Completed

Change Oxygen Consumption Following Intravitreal Treatment of Lucentis (Ranibizumab) in Eyes With Diabetic Macular Edema

Diabetic Macular Edema

Japan
Cairo University

Unknown

Intravitreal Diclofenac Versus Intravitreal Ranibizumab for the Treatment of Diabetic Macular Edema.

Diabetic Macular Edema

Egypt
Sun Yat-sen University

Completed

Comparison of PDT, Intravitreal Ranibizumab and Combination for Polypoidal Choroidal Vasculopathy Under 1+PRN Regimen

Polypoidal Choroidal Vasculopathy

China
Jiangsu T-Mab Biopharma Co.,Ltd

Unknown

A Study of Multiple Intravitreal Injection TK001 in Patients With Neovascular Age-related Macular Degeneration

Neovascular Age-Related Macular Degeneration

China
Allergan

Completed

Safety and Pharmacokinetics of Abicipar Pegol Intravitreal Injections in Patients With Neovascular AMD

Macular Degeneration

United States

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