Search clinical trials for: Programmed Cell Death 1

Total 90588 results

Merck Sharp & Dohme LLC

Active, not recruiting

Study of Pembrolizumab (MK-3475) Versus Placebo in Participants With Esophageal Carcinoma Who Are Receiving Chemotherapy and Radiation Therapy (MK-3475-975/KEYNOTE-975)

Esophageal Squamous Cell Carcinoma (ESCC) | Gastroesophageal Junction Carcinoma (GEJC) | Esophageal Adenocarcinoma (EAC)

China, Canada, United States, Argentina, Belgium, Brazil, Chile, Czechia, Denmark, Estonia, France, Germany, Guatemala, Hong Kong, Hungary, Italy, Japan, Korea, Republic of, Mexico, Peru, Philippines, Portugal, Romania, Russian Federation and more
Merck Sharp & Dohme LLC

Completed

Study of Pembrolizumab (MK-3475) vs Standard Therapy in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Carcinoma (MK-3475-177/KEYNOTE-177)

Colorectal Carcinoma
Centre Jean Perrin
Université d'Auvergne; Institut National de Recherche pour l'Agriculture, l... and other collaborators

Recruiting

Microbiota and the Lung Cancer (MICA)

Non Small Cell Lung Cancer

France
Ondokuz Mayıs University
Hacettepe University

Recruiting

Home-Based Action Observation Training for Chewing and Swallowing Function

Cerebral Palsy | Chewing Disease | Action Obervation Training

Turkey
Kirsehir Ahi Evran Universitesi

Not yet recruiting

The Effect of Gentle Human Touch and Kangaroo Care on Pain and Crying Physiological Parameters During Hepatitis-B Vaccination in a Newborn

Pain

Turkey
Southwest Hospital, China

Unknown

Clinical Application of Cholangiojejunostomy in the Surgical Treatment of Cholelithiasis With Moderate Dilatation of Common Bile Duct

Cholelithiasis | Cholangiojejunostomy

China
Incyte Corporation
Merck Sharp & Dohme LLC

Completed

Pembrolizumab Plus Epacadostat vs Pembrolizumab Plus Placebo in Metastatic Non-Small Cell Lung Cancer (KEYNOTE-654-05/ECHO-305-05)

Lung Cancer

Spain, Ireland, Canada, Denmark, Japan, Israel, Korea, Republic of, Malaysia, United States, Turkey, Italy, Ukraine, Switzerland, Russian Federation, Poland, Australia, Estonia, United Kingdom
Gazi University
Hacettepe University; Cukurova University; Marmara University; Istanbul University and other collaborators

Unknown

Evaluation of Status of Early Reached Target Enteral Nutrition and IFABP as Biomarker of Feeding Intolerance in Critically Ill Children (ERTENIFABPICU)

Enteral Nutrition | Feeding Intolerance | Intestinal Fatty Acid Binding Protein

Germany
Taiho Pharmaceutical Co., Ltd.

Completed

The Comparative Trial of UFT + TAM With CMF + TAM in Adjuvant Therapy for Breast Cancer (CUBC)

Breast Cancer

Japan
Merck Sharp & Dohme LLC

Terminated

Study of Preladenant (MK-3814) Alone and With Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3814A-062)

Neoplasm

United States, Canada, Israel
University of Bath
Arla Foods

Completed

The Dose Response of Calcium Co-ingested With Protein on GLP-1 Concentrations (PROCAL)

GLP-1 Concentration

United Kingdom
Stony Brook University

Completed

Trial With Deltex Cardio in Elective Bowel Resection Patients

1 Fluid Management

United States
Bristol-Myers Squibb

Completed

Study of the Safety & PK of INX-08189 in Chronically-infected HCV, Treatment-naïve Subjects

HCV (Genotype 1)

United States, Puerto Rico
Uwakwe Emmanuel Chijioke

Recruiting

Clonidine Versus Tranexamic Acid in Reduction of Blood Loss

Blood Loss

Nigeria
Merck Sharp & Dohme LLC

Withdrawn

Efficacy and Safety Study of Pembrolizumab (MK-3475) in Combination With Daratumumab in Participants With Relapsed Refractory Multiple Myeloma (MK-3475-668/KEYNOTE-668)

Multiple Myeloma

United States, Canada, France, Israel, Spain, Sweden
Haruhiko Fukuda
Ministry of Health, Labour and Welfare, Japan

Completed

A Phase II Study of Stereotactic Body Radiation Therapy in Patients With T1N0M0 Non-small Cell Lung Cancer (JCOG0403)

T1N0M0 Non-small Cell Lung Cancer

Japan
Merck Sharp & Dohme LLC

Recruiting

Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC) (MK-3475-676/KEYNOTE-676)

High-risk Non-muscle Invasive Bladder Cancer

Canada, Belgium, United States, Australia, Austria, France, Germany, Greece, Hungary, Italy, Japan, Korea, Republic of, Malaysia, Netherlands, Peru, Poland, Portugal, Spain, Switzerland, Turkey, United Kingdom, China, Brazil, Colombia, ... and more
Jingyuan,Xu

Unknown

Endothelial Cell Specific Molecule-1 (ESM-1): a Novel Biomarker for ARDS Endothelial Injury

Evaluate the Correlation Between the Level of ESM-1 and the Prognosis of the Patients With ARDS

China
Haruhiko Fukuda
Ministry of Health, Labour and Welfare, Japan

Completed

Trial of TP Versus TC Regimens for Stage IVb, Persistent, or Recurrent Cervical Cancer (JCOG0505, CC-TPTC-P3)

Uterine Cervical Neoplasms

Japan
Federal Research Institute of Pediatric Hematology...

Active, not recruiting

Preventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Calcineurin Inhibitor at Patients With Hemoblastosis

Myelodysplastic Syndromes | Juvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Myeloblastic Leukemia | Malignant Lymphoma | Biphenotypic Acute Leukemia

Russian Federation
Royal College of Surgeons, Ireland
Enterprise Ireland; Dublin City University

Unknown

F-Point Validation Study (F-Point)

Low Fibrinogen

Ireland
Bristol-Myers Squibb

Completed

A Study of Treatment Patterns and Outcomes in Participants With Stage IIIA Melanoma Receiving Adjuvant Systemic Therapy

Melanoma

United States
Pfizer

Recruiting

A Study of PF-07820435 as a Single Agent and in Combination in Participants With Advanced Solid Tumors

Melanoma | Neoplasms | Renal Cell Carcinoma | Non-small-cell Lung Cancer | Squamous Cell Carcinoma of the Head and Neck | Urothelial Carcinoma | Colorectal Carcinoma | Ovarian Carcinoma

Puerto Rico, Japan, United States
Daniela Matei, MD
Merck Sharp & Dohme LLC; Hoosier Cancer Research Network

Completed

Pembro/Carbo/Taxol in Endometrial Cancer

Endometrial Cancer | Endometrial Adenocarcinoma

United States
Peking University

Not yet recruiting

Pembrolizumab and Photodynamic Therapy in Previously Treated Metastatic Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma

China
Merck Sharp & Dohme LLC

Active, not recruiting

Substudy 03A: A Study of Immune and Targeted Combination Therapies in Participants With First Line (1L) Renal Cell Carcinoma (MK-3475-03A)

Carcinoma, Renal Cell

Spain, United States, Australia, Canada, Chile, Colombia, France, Hungary, Israel, Korea, Republic of, Netherlands, New Zealand, Poland, United Kingdom
Incyte Corporation
Merck Sharp & Dohme LLC

Active, not recruiting

Pembrolizumab (MK-3475) Plus Epacadostat vs Standard of Care in mRCC (KEYNOTE-679/ECHO-302)

Renal Cell Carcinoma (RCC)

Canada, France, United States, Spain, United Kingdom, Italy, Taiwan, Australia, Norway, Korea, Republic of, Germany, Russian Federation, Japan, Brazil, Turkey, Ukraine, Hungary, New Zealand, Chile, Ireland
Merck Sharp & Dohme LLC

Active, not recruiting

Substudy 03B: A Study of Immune and Targeted Combination Therapies in Participants With Second Line Plus (2L+) Renal Cell Carcinoma (MK-3475-03B)

Carcinoma, Renal Cell

United States, Australia, Canada, Chile, France, Hungary, Israel, Korea, Republic of, Netherlands, New Zealand, Poland, Spain, United Kingdom
Merck Sharp & Dohme LLC
Eisai Inc.

Active, not recruiting

Safety and Efficacy of Lenvatinib (E7080/MK-7902) With Pembrolizumab (MK-3475) in Combination With Transarterial Chemoembolization (TACE) in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma (MK-7902-012/E7080-G000-318/LEAP-012)

Carcinoma, Hepatocellular

Colombia, Israel, Taiwan, United States, Australia, Brazil, Chile, China, Denmark, France, Germany, Hong Kong, Hungary, Ireland, Italy, Japan, Korea, Republic of, Netherlands, New Zealand, Norway, Portugal, Puerto Rico, Spain, Thailand, Turke... and more
iOx Therapeutics
Merck Sharp & Dohme LLC

Terminated

IMM60 and Pembrolizumab in Melanoma and NSCLC

Melanoma | Non-small Cell Lung Cancer

Spain, United States, United Kingdom
Ningbo Cancer Hospital

Unknown

PD-1 Antibody Expressing CAR-T Cells for EGFR Family Member Positive Advanced Solid Tumor

Advanced Malignancies | PD-1 Antibody | CAR-T Cells

China
Merck Sharp & Dohme LLC

Active, not recruiting

Perioperative Pembrolizumab (MK-3475) Plus Neoadjuvant Chemotherapy Versus Perioperative Placebo Plus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle-invasive Bladder Cancer (MIBC) (MK-3475-866/KEYNOTE-866) (KEYNOTE-866)

Bladder Cancer

Canada, United States, Australia, Belgium, Denmark, France, Germany, Hungary, Ireland, Israel, Italy, Japan, Korea, Republic of, Mexico, Poland, Russian Federation, Spain, Sweden, Thailand, Turkey, Ukraine, United Kingdom
Merck Sharp & Dohme LLC

Active, not recruiting

Pembrolizumab (MK-3475) Versus Placebo Following Surgery and Radiation in Participants With Locally Advanced Cutaneous Squamous Cell Carcinoma (MK-3475-630/KEYNOTE-630)

Carcinoma, Squamous Cell

Ukraine, United States, Argentina, Australia, Brazil, Canada, Chile, Colombia, France, Germany, Greece, Hungary, Ireland, Israel, Italy, Mexico, New Zealand, Norway, Poland, Portugal, Romania, Russian Federation, Spain, United Kingdom
Merck Sharp & Dohme LLC
Eisai Inc.

Active, not recruiting

Study of First-line Pembrolizumab (MK-3475) With Lenvatinib (MK-7902/E7080) in Urothelial Carcinoma Cisplatin-ineligible Participants Whose Tumors Express Programmed Cell Death-Ligand 1 and in Participants Ineligible for Platinum-containing Chemotherapy (MK-7902-011/E7080-G000-317/ LEAP-011)

Urothelial Carcinoma

Hungary, United States, Argentina, Australia, Canada, China, Denmark, France, Germany, Israel, Italy, Japan, Korea, Republic of, Netherlands, Poland, Russian Federation, Spain, Taiwan, Turkey, United Kingdom
Merck Sharp & Dohme LLC

Completed

Study of Pemetrexed+Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Participants With First Line Metastatic Nonsquamous Non-small Cell Lung Cancer (MK-3475-189/KEYNOTE-189)-Japan Extension Study

Non-Small-Cell Lung Carcinoma

Japan
Ningbo No. 1 Hospital

Recruiting

Underwater Endoscopic Mucosal Resection Versus Metal Clips With Hot Snare Polypectomy for Resection of Big Pedunculated Colorectal Polyps：a Randomized Controlled Trial

Haemorrhage | Pedunculated Colorectal Polyps

China
Ningbo No. 1 Hospital

Recruiting

Cold Snare Polypectomy Versus Hot Snare Polypectomy for Resection of Small Pedunculated Colorectal Polyps：a Randomized Controlled Trial

Haemorrhage | Pedunculated Colorectal Polyps

China
Ningbo No. 1 Hospital

Not yet recruiting

Association Between Time in Range and In-hospital Outcomes in Type 2 Diabetic Patients With Acute Coronary Syndrome

Type 2 Diabetes Mellitus | Acute Coronary Syndrome

China
Ningbo No. 1 Hospital

Recruiting

Effect of Nutritional Supplements on Clinical Outcomes in Patients With Prediabetes and Obesity

Obesity | PreDiabetes

China
Ningbo No. 1 Hospital

Not yet recruiting

Position Changes in Cirrhosis Hemorrhagic Spot Detection

Emergency Hemostasis

China
Ningbo No. 1 Hospital

Recruiting

A New Ligation Using the Double-loop Clips Technique Versus Traditional Techniques in the Treatment of Large Wounds After Endoscopic Resection

Polyps | Closure; Delay

China
Ningbo No. 1 Hospital

Recruiting

The Influence of Education During Waiting Time of Vaccination on the Knowledge Towards COVID-19 Among Chinese Residents

Covid19 | Knowledge, Attitudes, Practice

China
Ningbo No. 1 Hospital

Not yet recruiting

UEMR for Medium-sized Pedunculated Colon Polyps

Colon Polyp

China
Ningbo No. 1 Hospital

Completed

Weight Gain After Smoking Cessation and NAFLD

Type 2 Diabetes | Nonalcoholic Fatty Liver Disease

China
Ningbo No. 1 Hospital

Completed

Minimal Water Exchange Versus Left Water Exchange in Unsedated Colonoscopy

Water Exchange Colonoscopy

China
Ningbo No. 1 Hospital

Completed

FFI and PR Could Improve Bowel Cleansing.

Bowel Preparation

China
Ningbo No. 1 Hospital

Completed

External Validation of Models for Predicting Inadequate Bowel Preparation

Colonoscopy | Predictive Model | External Validation

China
University of Oran 1

Unknown

Bile Leaks After Biliary Surgery

Bile Leak | Anastomotic Leak Biliary | Biliary Tract Fistula

Algeria
Ningbo No. 1 Hospital

Completed

Mizone vs Water for Bowel Preparation.

Bowel Preparation

China
Ningbo No. 1 Hospital

Completed

Novel Stent Placement Technique for Intestinal Stenosis Assisted by an Ultrafine Endoscope

Colorectal Carcinoma

China

Search clinical trials for: Programmed Cell Death 1

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