Search clinical trials for: RBC transfusions

Total 615 results

St. Jude Children's Research Hospital
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Stroke With Transfusions Changing to Hydroxyurea

Hematologic Diseases | Anemia, Sickle Cell | Cerebrovascular Accident | Hemochromatosis

United States
Jack Yanovski
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Safety and Efficacy of Xenical in Children and Adolescents With Obesity-Related Diseases

Hypertension | Obesity | Diabetes Mellitus | Metabolic Disease | Sleep Apnea Syndrome

United States
St. Olavs Hospital

Completed

Tranexamic Acid, Hemorrhage and Transfusions After Combined Aortic Valve Replacement and Coronary Artery Bypass Surgery.

Hemorrhage

Norway
Martina Hansen's Hospital
Oslo University Hospital

Completed

Preoperative Versus Postoperative Start With Thromboprophylaxis in THA (Total Hip Arthroplasty)

Infection | Arthritis of the Hip | Transfusion Related Complications | Wound Discharge

Norway
Instituto do Cancer do Estado de São Paulo

Unknown

Transfusion Requirements in Critically Ill Oncologic Patient (TRICCOP)

Anemia

Brazil
Paul Stricker
Children's Anesthesiology Associates, Ltd.; Thomas B. and Jeannette E. Laws...

Completed

Amicar Pharmacokinetics of Children Having Craniofacial Surgery

Craniosynostosis

United States
M.D. Anderson Cancer Center
Celgene Corporation

Terminated

Lenalidomide and Darbepoetin in Low-Intermediate Risk Myelodysplastic Syndrome (MDS)

Leukemia

United States
Federico II University

Completed

Tolerance to a New Free Amino Acid-based Formula in Children With IgE or Non-IgE-mediated Cow's Milk Allergy

Cow's Milk Allergy

Italy
Cephalon

Terminated

Safety and Efficacy of SDX-101 (R-Etodolac) in Combination With Chlorambucil, and That of Chlorambucil Alone, in Patients With Chronic Lymphocytic Leukemia (CLL)

Chronic Lymphocytic Leukemia

France, Germany, Poland, Sweden, United Kingdom
Salient Surgical Technologies

Terminated

Salient Aquamantys Spine Trial

Blood Loss

United States
Università Politecnica delle Marche
Azienda Ospedaliero, Universitaria Ospedali Riuniti

Completed

Effects on Septic Patient's Microcirculation of the Transfusion of Different Types of Concentrated RBCs.

Septic Patients

Italy
Federico II University

Unknown

Nutrition in Children With Food Allergy

Food Allergy

Italy
Joint Implant Surgeons, Inc.
Medtronic; Mount Carmel Health System

Completed

Efficacy of Aquamantys for Reducing Transfusions With Anterior Supine Intermuscular Approach Total Hip Arthroplasty (Aquamantys)

Arthritis, Rheumatoid | Osteonecrosis | Hip Dislocation, Congenital | Osteoarthritis, Hip | Joint Deformities, Acquired

United States
Novartis Pharmaceuticals

Completed

Safety & Efficacy of ICL670 vs. Deferoxamine in Beta-thalassemia Patients With Iron Overload Due to Blood Transfusions

Beta-Thalassemia

United States
Cardiochirurgia E.H.

Terminated

Blood Sparing Strategies: Omni-stat Routinary Use in Cardiac Surgery. A Prospective Randomized Study.

Hemostasis

Italy
FerroKin BioSciences, Inc.

Completed

Safety and Pharmacokinetic Study of Escalating Multiple Doses of an Iron Chelator in Patients With Iron Overload

Beta-thalassemia | Transfusional Iron Overload

United States, Australia, Thailand
Takeda

Completed

Efficacy and Safety of Azilsartan Medoxomil and Chlorthalidone in Participants With Moderate to Severe Hypertension

Essential Hypertension

United States, Russian Federation
Ain Shams University

Unknown

Study Of Efficacy,Safety of Combined Deferasirox and Deferiprone Versus Combined Deferiprone and Desferal In Conditions of Iron Overload

Sickle Cell Disease | Beta-thalassemia Major | Iron Hemosiderosis

Egypt
Mayo Clinic

Completed

Transfusion-Induced Alterations of Pulmonary and Immune Function in Mechanically Ventilated Patients (TRALI2)

Blood Protein Disorders | Pulmonary Edemas

United States
Sunnybrook Health Sciences Centre
Canadian Blood Services; National Blood Foundation; Canadian Department of National...

Completed

The Trauma- Formula-Driven Versus Lab-Guided Study (TRFL Study) (TRFL)

Hemorrhagic Shock | Trauma Coagulopathy

Canada
Vakzine Projekt Management GmbH
University of Stellenbosch; Farmovs-Parexel Bloemfontein, Republic of South... and other collaborators

Completed

Dose-Escalation Study on Safety and Immunogenicity of VPM1002 in Comparison to BCG in Healthy Volunteers in South Africa

Tuberculosis

South Africa
Bucci Laser Vision Institute

Completed

Is Omega-3 Fatty Acid Red Blood Cell (RBC) Saturation Product Dependent?

Cardioprotective Levels

United States
Novartis Pharmaceuticals

Completed

Extension Study of the Efficacy and Safety of Deferasirox Treatment in Beta-thalassemia Patients With Transfusional Hemosiderosis (Study Amended to 2-year Duration) (ESCALATOR)

Iron Overload | Hemosiderosis | Beta-thalassemia Major | Rare Anemia

Egypt, Oman, Saudi Arabia, Syrian Arab Republic, Lebanon
HaEmek Medical Center, Israel

Completed

Blood Transfusions in Thalassemia Patients, Complications and Adverse Effects

Sickle Cell Anemia | Thalassemia

Israel
Sanquin Research & Blood Bank Divisions
Erasmus Medical Center

Completed

Well Being of Obstetric Patients on Minimal Blood Transfusions (WOMB)

Anemia

Netherlands
Hormozgan University of Medical Sciences

Completed

Efficacy and Safety of Desferal Versus Osveral in Transfusional Iron Overload

Iron Overload | Thalassemia | Transfusion Related Complications

Iran, Islamic Republic of
Novartis Pharmaceuticals

Completed

Expanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic Iron Overload

Myelofibrosis | Sickle Cell Disease | Thalassemia | Diamond Blackfan Anemia

United States, Netherlands, Taiwan, Thailand, Italy, Germany, Spain, Canada, Belgium, Greece, Turkey, United Kingdom
Novartis Pharmaceuticals

Completed

Evaluation of the Safety, Tolerability, Pharmacokinetics (PK) and Effects on Liver Iron Concentration of ICL670 Relative to Deferoxamine(DFO).

Sickle Cell Disease

United States, Italy, United Kingdom, France, Canada
Novartis Pharmaceuticals

Completed

Safety and Efficacy of Deferasirox (ICL670) in Patients With Iron Overload Resulting From Hereditary Hemochromatosis

Iron Overload | Hereditary Hemochromatosis

United States, Germany, Italy, Australia, Canada, France
Novartis Pharmaceuticals

Completed

An Extension Study of Iron Chelation Therapy With Deferasirox (ICL670) in β-thalassemia Patients With Transfusional Iron Overload

Transfusional Iron Overload in β-thalassemia

United States, Greece, Argentina, Germany, Belgium, Italy, United Kingdom, France, Tunisia, Canada, Turkey, Brazil
Novartis Pharmaceuticals

Completed

Study of Deferasirox Relative to Subcutaneous Deferoxamine in Sickle Cell Disease Patients

Iron Overload | Sickle Cell Disease | Hemolytic Anemia

United States, Canada
Janssen-Cilag B.V.

Completed

A Study of the Safety and Effectiveness of Epoetin Alfa on Hemoglobin Levels and Blood Transfusions in Cancer Patients Receiving Chemotherapy

Neoplasms | Anemia
Johnson & Johnson Pharmaceutical Research & Development...

Completed

Epoetin Alfa for the Treatment of Anemia Resulting From Chronic Lymphocytic Leukemia

Neoplasms | Quality of Life | Cancer | Anemia | Leukemia, Lymphocytic | Leukemia, Lymphocytic, Chronic
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Determine Whether Epoetin Alfa Can Reduce the Need for Blood Transfusions in Patients During the Period of Time Around Major Orthopedic Surgery.

Anemia | Blood Transfusion | Orthopedic Procedures
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Determine the Safety of Epoetin Alfa and Whether Epoetin Alfa Can Reduce the Need for Blood Transfusions in Patients After Major Orthopedic Surgery.

Anemia | Blood Transfusion | Orthopedic Procedures
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Evaluate the Safety and Effectiveness of Epoetin Alfa Versus Placebo in Facilitating the Presurgical Collection of Blood to be Used for Self-donation During Surgery on the Spine, Hip, or Knee.

Anemia | Orthopedic Procedures | Blood Transfusions, Autologous
Janssen-Ortho Inc., Canada

Completed

A Study to Evaluate the Safety and Efficacy of Epoetin Alfa Versus Placebo to Reduce the Need for Blood Transfusions and Reduce the Occurrence of Severe Anemia During the Time Period Surrounding Total Hip Replacement Surgery

Anemia
Novartis Pharmaceuticals

Completed

Extension Study of Iron Chelation Therapy With Deferasirox in β-thalassemia and Rare Chronic Anemia Patients

Anemia | Hemosiderosis

United States, Germany, Belgium, United Kingdom, Italy, Canada, France
University Health Network, Toronto

Terminated

Effect of Decreased Pump Prime Volume on Blood Transfusions and Postoperative Complications of Patients Undergoing High Risk Cardiac Surgical Procedures

Cardiac Surgery
Celgene Corporation
ICON Clinical Research

Completed

Lenalidomide Versus Placebo in Myelodysplastic Syndromes With a Deletion 5q[31] Abnormality

Myelodysplastic Syndromes

Germany, Israel, United Kingdom, Spain, Belgium, Italy, France, Netherlands, Sweden
University of Edinburgh
NHS Lothian; Chief Scientist Office of the Scottish Government; Transfusion Medicine...

Completed

Restrictive and Liberal Transfusion Strategies in Intensive Care (RELIEVE)

Anemia | Blood Transfusion | Intensive Care

United Kingdom
Assistance Publique - Hôpitaux de Paris
Association pour l'Etude des Fonctions Digestives (AEFD)

Unknown

Safety and Efficacy of Oral Deferasirox in Patients With Porphyria Cutanea Tarda

Porphyria Cutanea Tarda

France
Janssen-Cilag B.V.

Completed

A Study of the Effectiveness and Safety of Treatment With Epoetin Alfa on Hemoglobin Levels, Red Blood Cell Transfusions, and Quality of Life in Patients With Cancer Receiving Platinum-containing Chemotherapy

Anemia | Neoplasm
PharmAthene, Inc.
United States Department of Defense; Quintiles, Inc.; QPS Holdings LLC

Completed

First Time in Human Study of Protexia

Intervention for Nerve Agent Exposure

United States
St. Justine's Hospital
Nancy Robitaille, MD

Terminated

Maintaining a Higher Level of Haemoglobin: Effect on the White Cells After Bone Marrow Transplantation in Children.

Neutropenia

Canada
Sheba Medical Center

Completed

MRI Evaluation of Iron Overload in the Heart, Liver and Pancreas in Patients Receiving Multiple Blood Transfusions.

Iron Overload

Israel
Goethe University

Completed

Modified Ultrafiltration in Cardiac Surgery

Blood Loss | Coagulopathy | Rethoracotomy | Transfusion Requirements

Germany
Cardiochirurgia E.H.

Completed

ICU Cell Saver to Reduce Blood Transfusions in Cardiac

Cardiac Surgery | Blood Transfusion

Italy
Instituto do Coracao

Unknown

TRACS STUDY: Transfusion Requirements After Cardiac Surgery (TRACS)

Cardiac Surgery

Brazil
Isfahan University of Medical Sciences
Madaus Inc

Unknown

Therapeutic Effects of Silymarin in Patients With B-thalassemia Major

Iron Overload | Beta-thalassemia Major

Iran, Islamic Republic of

Search clinical trials for: RBC transfusions

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