Search clinical trials for: Single dose

Total 25969 results

Luye Pharma Group Ltd.
Parexel

Completed

A Pharmacokinetic Similarity Study in Healthy Male Subjects to Evaluate Pharmacokinetics, Pharmacodynamics, Safety and Immunogenicity of LY06006 Versus US-Prolia and EU-Prolia by Single-dose Subcutaneous Injection

Healthy

Germany
GlaxoSmithKline

Completed

Phase 1, Single and Repeat Dose Study to Assess Safety, Tolerability, and Pharmacokinetics (PK) of GSK3923868 in Participants With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Germany
Pieris Australia Pty Ltd

Completed

Study of Single and Multiple Doses of PRS-220 Administered by Oral Inhalation in Healthy Subjects

Healthy

Australia
Achieve Life Sciences

Completed

Study to Evaluate the Effect of Renal Impairment and Dialysis Treatment on the Pharmacokinetics of a Single 3 mg Cytisinicline Dose

Renal Impairment

Spain, Portugal
Telavant, Inc.
Pfizer

Completed

Evaluation of Safety, Tolerability and Pharmacokinetics of Single Dose of PF-06480605 in Japanese Healthy Participants

Healthy

Japan
Telavant, Inc.
Pfizer

Completed

Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Intravenous and Multiple Subcutaneous and Intravenous Doses of PF-06480605 in Healthy Subjects.

Healthy

United States
Achieve Life Sciences

Completed

Study to Evaluate Effect of Food on Bioavailability of Single 3 mg Tablet and Pharmacokinetics (PK) of Multiple 3 mg Doses in Healthy Adult Smokers

Smoking Cessation

Portugal
Graviton Bioscience Corporation

Completed

Safety, Tolerability, and Pharmacokinetic Study of Single Ascending Dose of GV101 in Healthy Subjects

Phase 1

United States
Merck KGaA, Darmstadt, Germany

Completed

First-in-Human Trial of Single Ascending Dose, Multiple Ascending Dose and Malaria Challenge Model in Healthy Participants

Healthy

Australia
TenNor Therapeutics (Suzhou) Limited

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Food Effect of TNP-2198 Capsules After Single Oral Dose in Healthy Participants

Helicobacter Pylori Infection

China
Bristol-Myers Squibb

Completed

A Study to Assess the Effects on the Single-Dose Drug Levels of Mavacamten in Healthy Participants

Healthy Participants

United States
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Completed

A Single-dose Study of Octreotide Injection in Healthy Adult Subjects

Acromegaly

China
Kashiv BioSciences, LLC

Completed

Open Label, Sequential Dosing , Single Ascending Dose and Multiple Dose Safety Tolerability and Pharmacokinetic Study

Metastatic Breast Cancer

Jordan
London School of Hygiene and Tropical Medicine
Mwanza Intervention Trials Unit, National Institute for Medical Research; York... and other collaborators

Active, not recruiting

Adding Male Single Dose HPV Vaccination to Female HPV Vaccination in Tanzania (Add-Vacc)

HPV Infection | Vaccine Preventable Disease

Tanzania
BioMarin Pharmaceutical

Completed

Single-Arm Study To Evaluate The Efficacy and Safety of Valoctocogene Roxaparvovec in Hemophilia A Patients at a Dose of 4E13 vg/kg (GENEr8-2)

Hemophilia A

United States
Sanofi

Completed

Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intravenous and Subcutaneous Single and Repeated Doses of SAR441344 in Healthy Adult Subjects

Healthy Volunteers

United States
Sanofi

Completed

Study of a Quadrivalent Meningococcal Conjugate Vaccine as a Single Dose Compared With a Single Dose of a Meningococcal Reference Vaccine in Children, Adolescents, and Adults 2 to 55 Years of Age

Meningococcal Immunisation (Healthy Volunteers)

Japan
Millennium Pharmaceuticals, Inc.

Completed

A Study of a Single Intravenous Infusion Dose of TAK-925 in Participants With Idiopathic Hypersomnia

Idiopathic Hypersomnia

United States, Japan
First Affiliated Hospital of Fujian Medical University

Completed

Study of 18F-Thretide PET/CT in Patients With Prostate Cancer

Prostate Cancer

China
Crinetics Pharmaceuticals Inc.

Completed

Single and Multiple-Ascending Dose Study of CRN04894 in Healthy Volunteers

Healthy Volunteers

United States
Sarepta Therapeutics, Inc.

Active, not recruiting

A Gene Transfer Single Dose Study to Evaluate the Safety, Tolerability and Efficacy of SRP-9003 in Non-Ambulatory and Ambulatory Participants With Limb Girdle Muscular Dystrophy, Type 2E/R4 (Beta-Sarcoglycan [β-SG] Deficiency)

Limb Girdle Muscular Dystrophy

United States
Children's National Research Institute
Foundation to Eradicate Duchenne

Active, not recruiting

Single Escalating Dose Pilot Trial of Canakinumab (ILARIS®) in Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy

United States
Takeda

Completed

Effect of Food on the Pharmacokinetics of Single Oral Dose Administration of a Fixed-Dose Combination of SYR-322 and Metformin Hydrochloride in Healthy Adult Male Subjects

Clinical Pharmacology

Japan
University of Nebraska
Genzyme, a Sanofi Company

Completed

Improved Induction and Maintenance Immunosuppression in Kidney Transplantation

End-stage Renal Disease

United States
University of Florida
Live Like Bella Pediatric Cancer Research

Completed

Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation

Common Variable Immunodeficiency | Severe Combined Immunodeficiency | Sickle Cell Disease | Hurler Syndrome | Chronic Granulomatous Disease | Thalassemia | Wiskott-Aldrich Syndrome | Adrenoleukodystrophy | X-linked Lymphoproliferative Disease | Diamond Blackfan Anemia | Bone Marrow Failure Syndrome | Hemophagocytic... and other conditions

United States
CTI BioPharma
Covance

Completed

To Evaluate the Cardiac Safety and PK Following a Single Oral Dose Administration of Pacritinib in Healthy Subjects

Healthy Subjects

United States
Amgen

Terminated

Single and Multiple Ascending Dose Study of AMG 171 in Subjects With Obesity

Obesity

United States
Eisai Co., Ltd.

Completed

A Single and Multiple Dose Study of Dotinurad in Chinese Healthy Participants

Healthy Volunteers

China
Pfizer
Emergent Product Development Seattle LLC

Completed

Study Evaluating Single Doses Of SBI-087 in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

United States, Canada
Wuhan Createrna Science and Technology Co., Ltd

Completed

A Study of Single-dose MY008211A in Healthy Adults

Paroxysmal Nocturnal Hemoglobinuria

China
Viela Bio (acquired by Horizon Therapeutics)

Completed

A Study of Single and Multiple Ascending Doses of VIB1116 in Rheumatic Diseases

Dendritic Cell -Mediated Rheumatic Diseases

United States, Poland
CSL Behring

Completed

Safety of Single Doses of CSL889 in Adult Patients With Sickle Cell Disease

Sickle Cell Disease

United States, United Kingdom, Netherlands
Enanta Pharmaceuticals, Inc

Completed

A Study of EDP-323 in Healthy Subjects

RSV Infection

United States
ViiV Healthcare

Completed

First-Time-in-Human (FTIH) Study to Evaluate the Safety, Tolerability and Pharmacokinetics (PK) of VH4004280 in Healthy Participants

HIV Infections

United States
AstraZeneca

Completed

A Study to Investigate the Safety, Tolerability and Effects of AZD8630 in Healthy Subjects and Subjects With Asthma on Inhaled Corticosteroids and Long-acting Beta-agonists

Asthma

United States, Germany, United Kingdom
McMaster University

Completed

Single Dose Antenatal Corticosteroids (SNACS) for Women at Risk of Preterm Birth (SNACS Pilot)

Pregnancy Complications | Obstetric Labor Complications | Preterm Birth | Obstetric Labor, Premature | Complication of Prematurity

Canada
Beijing Tongren Hospital

Completed

Optimization of Intestinal Preparation in Older Patients

Colonoscopy | Older Adults

China
Madrigal Pharmaceuticals, Inc.

Completed

Ascending Single-Dose Study to Evaluate VIA-3196 in Healthy Subjects

Drug Safety

United States
Sanofi

Completed

A Single Ascending Dose Study to Characterize the Pharmacokinetics, Safety, and Tolerability of SAR441566 in Healthy Adult Japanese Male Participants.

Rheumatoid Arthritis

United States
Pfizer

Completed

A Single Dose Study To Test Two Pediatric Forms Of Ritlecitinib Compared With Adult Ritlecitinib In Healthy Adults

Healthy Participants

United States
Bayer

Completed

A Study to Learn How the Study Treatment BAY3283142 Taken as Single Dose by Mouth Moves Into, Through, and Out of the Body, How Safe it is, and How it Affects the Body in Participants With Reduced Kidney Function Compared to Participants With Normal Kidney Function of Similar Age, Gender, and Weight

Renal Impairment | Chronic Kidney Disease | Healthy Volunteers

Germany
Boehringer Ingelheim

Completed

Spesolimab (BI 655130) Single Dose in Generalized Pustular Psoriasis

Psoriasis

Taiwan, Malaysia, France, Japan, Korea, Republic of, Tunisia
Janssen Research & Development, LLC

Completed

A Single and Multiple Ascending Dose Study of Subcutaneously Administered JNJ-75220795

Fatty Liver Disease

United States
VectivBio AG

Completed

A Phase 1, Open-Label Evaluation of the Pharmacokinetics and Safety of a Single Dose of Apraglutide in Subjects With Normal and Impaired Hepatic Function

Hepatic Impairment

Germany, Slovakia
Shanghai Belief-Delivery BioMed Co., Ltd

Active, not recruiting

Evaluation of the Safety and Efficacy of Hemophilia B Gene Therapy Drug

Hemophilia B

China
Haisco Pharmaceutical Group Co., Ltd.

Completed

Single Escalating Dose Study Of HSK7653 In Healthy Subjects

T2DM (Type 2 Diabetes Mellitus)

China
Boehringer Ingelheim

Completed

Single Rising Doses of BI 655064 in Healthy Chinese and Japanese Male Volunteers

Healthy

Japan, Korea, Republic of
ConSynance Therapeutics

Completed

A Pharmacokinetic and Safety Study of CSTI-500 in Subjects With Prader-Willi Syndrome

Prader-Willi Syndrome

United States
AstraZeneca
Parexel

Completed

A Study to Assess Safety, Tolerability, PK and PD of AZD2373 in Healthy Male Participants of Sub-Saharan West African Ancestry

Healthy Volunteers

United States
Portola Pharmaceuticals

Completed

An Open-Label, Single-Dose, Mass-Balance Study to Assess the Disposition of 14C-Labeled PRT054021 in Healthy Male Subjects

Health Volunteers

3

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