Search clinical trials for: treatment naïve

Total 63842 results

Central South University

Not yet recruiting

Clinical Features and Prognostic Markers in Adult Patients With AE Requiring ICU Treatment

Autoimmune Encephalitis
RemeGen Co., Ltd.

Not yet recruiting

A Study of Telitacicept for the Treatment of Generalized Myasthenia Gravis (RemeMG)

Generalized Myasthenia Gravis
Ming Wei

Recruiting

Ischemic Post-conditioning in the Treatment of Acute Ischemic Stroke

Acute Ischemic Stroke | Large Vessel Occlusion | Intracranial Artery Occlusion With Cerebral Infarction | Endovascular Treatments

China
Qilu Pharmaceutical Co., Ltd.

Not yet recruiting

QL0911 for the Treatment of Cancer Treatment-Induced Thrombocytopenia

Cancer Treatment-Induced Thrombocytopenia
Central Institute of Mental Health, Mannheim

Not yet recruiting

Maintenance ElectroConvulsive Therapy in Clozapine RESISTant Schizophrenia - the MECT-RESIST Trial (MECT-RESIST)

Schizophrenia | Treatment Resistant Schizophrenia

Germany
Revaz Dzhindzhikhadze

Not yet recruiting

Early Versus Ultra Early Surgical Treatment of Ruptured Intracranial Aneurysms

Aneurysmal Subarachnoid Hemorrhage
Washington State University
Managed Health Connections

Recruiting

Automated Reinforcement Management Systems, Phase II (ARMS II)

Alcohol Use Disorder

United States
Amsterdam UMC, location VUmc
Foundation for the National Institutes of Health

Not yet recruiting

Assessment of PET Tracers to Evaluate T Cell Change and Activation in Relation to Immunotherapy Treatment Response in Non-Small Cell Lung Cancer (iRelate)

NSCLC

Netherlands
University Hospital Heidelberg

Not yet recruiting

Pasireotide as Maintenance Treatment in Synovial Sarcoma and Desmoplastic Small Round Cell Tumor (PAMSARC)

Synovial Sarcoma | Desmoplastic Small Round Cell Tumor

Germany
Stemline Therapeutics, Inc.

Not yet recruiting

A Study of Tagraxofusp in Combination With Venetoclax and Azacitidine in Adults With Untreated CD123+ Acute Myeloid Leukemia Who Cannot Undergo Intensive Chemotherapy

Acute Myeloid Leukemia

United States
Yuwei Qiu

Not yet recruiting

To Evaluate the Efficacy and Safety of Tegileridine and Oliceridine Injections in the Treatment of Postoperative Pain

Analgesia
I.M. Sechenov First Moscow State Medical University

Recruiting

Optimization of Bacterial Vaginosis Treatment in Women of Reproductive Age

Bacterial Vaginosis

Russian Federation
RenJi Hospital

Recruiting

Clinical Exploration Trial of YOLT-101 in the Treatment of Familial Hypercholesterolemia (FH)

Familial Hypercholesterolemia

China
Ningbo No. 1 Hospital

Recruiting

First-line Treatment of PCNSL With the Combination of Orelabrutinib, Rituximab, and Methotrexate (ORM Regimen)

Primary Central Nervous System Lymphoma

China
Shanghai Jiaolian Drug Research and Development...
Shanghai Pharmaceuticals Holding Co., Ltd

Not yet recruiting

A Clinical Study of B007 in the Treatment of Pemphigus.

Pemphigus

China
Anastasia Vishnevetsky, MD, MPH
argenx

Not yet recruiting

Efgartigimod for the Treatment of Acute Optic Neuritis (PET-AON)

Optic Neuritis

United States
Shanghai Chest Hospital

Not yet recruiting

Efficacy and Safety of Multimode Thermal Therapy in the Treatment of Early Peripheral Lung Cancer

Lung Cancer

China
AstraZeneca

Not yet recruiting

A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic Inflammatory Myopathies (Polymyositis and Dermatomyositis) (JASMINE)

Polymyositis, Dermatomyositis

United States, Denmark, France, Italy, Spain, Belgium, India, Vietnam, Japan, China, Israel, Austria, Canada, Germany, Taiwan, United Kingdom, Australia, Hungary, Netherlands, Sweden, Brazil, Bulgaria, Poland, Mexico, Czechia
RenJi Hospital

Recruiting

Effectiveness and Health Economics of Endoluminal Treatment of Autologous Arteriovenous Endovascular Fistula Failure

Hemodialysis Access Failure

China
Capsicure, LLC

Not yet recruiting

Derm-Maxx in Patients With Diabetic Foot Ulcers Unresponsive to Standard of Care Treatment Alone

Diabetic Foot Ulcer
Yongyong MA

Recruiting

Daratumumab/Daratumumab and Hyaluronidase-fihj in Combination With Pomalidomide and Dexamethasone for the Treatment of Patients With Newly Diagnosed AL Amyloidosis: a Prospective, Multicenter, Single-arm Study

Amyloid Light-chain Amyloidosis

China
University Health Network, Toronto
Academic Medical Organization of Southwestern Ontario; York University; Toronto...

Not yet recruiting

Online Psychology Program for Chronic Pain After Surgery (ADOPT-TPS)

Pain, Acute | Pain, Chronic | Post-surgical Pain | Post-Surgical Pain, Chronic

Canada
Jin-hong Chen

Not yet recruiting

Cadonilimab Combined With Regorafenib as A Third-line Treatment in Patients With MSS CRLM

CRC

China
Peking Union Medical College Hospital

Recruiting

Orelabrutinib Combined With Obinutuzumab and Lenalidomide (OGL Regimen) as First-line Treatment for Marginal Zone Lymphoma.

Marginal Zone Lymphoma

China
Rutgers, The State University of New Jersey
National Institute of Mental Health (NIMH); Louisiana State University Health...

Not yet recruiting

Virtual Reality Treatment for Emerging Adults With ADHD

Attention Deficit Hyperactivity Disorder

United States
Henan Cancer Hospital

Not yet recruiting

Clinical Study of Trop2 CAR-NK in the Treatment of Relapsed/Refractory Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer NSCLC
VA Office of Research and Development

Not yet recruiting

Developing a Smartphone Application to Support Veteran Opioid Use Disorder Treatment

Quality of Life | Opioid-Related Disorders | Psychosocial Functioning

United States
AstraZeneca

Recruiting

Patient Characteristics, Treatment Patterns and Outcomes of Patients Enrolled in the Tezepelumab Patient Access Programme; a Retrospective, Observational Medical Chart Review Conducted in UK Severe Asthma Centres (TPAP)

Severe Asthma

United Kingdom
Oui Therapeutics, Inc.
National Institute of Mental Health (NIMH)

Not yet recruiting

Pilot Trial of Mobile Technology for Adolescent Suicidality

Suicidal Ideation
University of Coimbra

Recruiting

Erythritol Air Polishing in Mucositis Treatment

Peri-implant Mucositis

Portugal
University of British Columbia
IBD Centre of BC; GI Research Institute; Pacific Gastroenterology Associates

Not yet recruiting

Predicting IBD Treatment Outcomes With Gut Microbiome Analysis (OPTIMIST)

Inflammatory Bowel Diseases | Crohn Disease
Academisch Medisch Centrum - Universiteit van Amsterdam...
GGZ Eindhoven (participating site); Mental Care Group (i.e., HSK group and... and other collaborators

Recruiting

Improving Treatment of Major Depressive Disorder by Reducing Negative Future-Oriented Mental Imagery (PROFIT)

Major Depressive Disorder | Cognitive Behavioral Therapy | Mental Imagery

Netherlands
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Regorafenib in Combination With Venetoclax and Azacitidine for the Treatment of Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Myelodysplastic Syndrome | Myelodysplastic Syndrome/Acute Myeloid Leukemia

United States
Assiut University

Not yet recruiting

Treatment of Displaced Medial Epicondyle Fractures In Children

Fractures, Bone
Tianjin Medical University Cancer Institute and...

Recruiting

Phase Ib/II Clinical Study of Adebrelimab in Combination With Decitabine, Albumin-bound Paclitaxel, and Gemcitabine for the First-line Treatment of Metastatic Pancreatic Cancer

Metastatic Pancreatic Cancer | Decitabine | Adebrelimab (SHR-1316)

China
Amsterdam UMC
ZonMw: The Netherlands Organisation for Health Research and Development

Not yet recruiting

Preeclampsia Intervention Netherlands (PI-NL)

Pre-Eclampsia | HELLP Syndrome | Pre-eclampsia or Eclampsia With Pre-existing Hypertension | HELLP | Pre-Eclampsia; Complicating Pregnancy | Pre-Eclampsia Onset Less Than 37 Weeks | Pre-Eclampsia as Antepartum Condition | Pre-Eclampsia; Affecting Fetus | HELLP Syndrome Complicating Pregnancy
Grit Biotechnology

Recruiting

Autologous Tumor-Infiltrating Lymphocyte (GT307) for Treatment of Patients With Solid Tumours

Adult

China
China Medical University Hospital

Recruiting

The Impact and Effect of Traditional Chinese Medicine Treatment on Organ Failure in Critically Ill Patients

Respiratory Failure | Morality | Delayed Gastric Emptying | Organ Failure, Multiple | Indigestion

Taiwan
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Mosunetuzumab and Polatuzumab Vedotin for the Treatment of Patients With Relapsed or Refractory Grade 1-3a Follicular Lymphoma

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3a Follicular Lymphoma | Refractory Grade 1 Follicular Lymphoma | Refractory Grade 2 Follicular Lymphoma | Refractory Grade 3a Follicular Lymphoma

United States
Bruce Cree
Kyverna Therapeutics

Recruiting

A Study of KYV-101, a CD19 CAR T Cell Therapy, in Participants With Treatment Refractory Progressive Multiple Sclerosis

Progressive Multiple Sclerosis

United States
McGill University Health Centre/Research Institute...

Not yet recruiting

Evaluating the Feasibility of elleFA App Implementation (elleFA)

Endometriosis
Umeå University
Region Norrbotten

Recruiting

Knee Osteoarthritis in the Region of Norrbotten (KORN)

Quality of Life | Osteoarthritis | Knee Osteoarthritis | Knee Injuries | Tibial Fractures | Patient Satisfaction | Complication of Treatment | Tibial Plateau Fractures

Sweden
University Health Network, Toronto

Not yet recruiting

A Study of High Dose Radiation Therapy for Locally Advanced Pancreatic Cancer That Responded to Initial Chemotherapy Treatment (ABLATE)

Locally Advanced Pancreatic Adenocarcinoma
Fundacio De Recerca Del Instituto De Microcirugia...

Recruiting

First in Human Study to Assess the Safety and the Efficacy of an Implantable Nitinol Device in the Treatment of Keratoconus

Keratoconus

Spain
Region Stockholm

Recruiting

Treatment of Distal Malignant Biliary Obstruction by Uncovered, Partially Covered, or Fully Covered Metal Stents

Bile Duct Cancer | Duodenal Cancer | Pancreatic Cancer Non-resectable | Papillary Carcinoma

Sweden
Bayer

Not yet recruiting

A Study to Learn More About How Well BAY 2927088 Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations in the Genes of Human Epidermal Growth Factor Receptor 2 (HER2) (SOHO-02)

Advanced Non-small Cell Lung Cancer | HER2 Mutation

United States, China, Korea, Republic of, Belgium, Hong Kong, Japan, Taiwan, Denmark, Germany, Israel, Poland, Italy, United Kingdom, Bulgaria, Czechia, Portugal, Switzerland, Greece, Turkey, Romania, Sweden, France, Singapore, Mexico, ... and more
Dermal Laboratories Ltd

Not yet recruiting

A Study to Evaluate the Emollient Performance of Doublebase Once in the Treatment of Atopic Eczema

Atopic Eczema
Chia Tai Tianqing Pharmaceutical Group Nanjing...

Not yet recruiting

A Extension Clinical Study of TQC2731 Injection in the Treatment of Chronic Sinusitis With Nasal Polyps

Chronic Rhinosinusitis With Nasal Polyps

China
Chang Gung Memorial Hospital

Not yet recruiting

Platelet Rich Fibrin Versus Platelet Rich Plasma for Microneedling Treatment of Facial Photoaging

Photoaging

Taiwan
VA Office of Research and Development

Not yet recruiting

Personalized Exercise Treatments for Older Veterans With Motoric Cognitive Risk Syndrome

Motoric Cognitive Risk Syndrome

United States

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