Search clinical trials for: Busulfan pharmacokinetics

Total 10900 results

Tianjin Medical University Cancer Institute and...
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

CMOEP in the Treatment of Untreated Peripheral T-cell Lymphoma

Peripheral T-cell Lymphoma

China
Children's Oncology Group

Recruiting

Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Mixed Phenotype Acute Leukemia

United States, Australia, Canada
Pacira Pharmaceuticals, Inc

Recruiting

Phase 1, Dose Escalation Study to Evaluate of Safety, Pharmacokinetics and Pharmacodynamics of Liposomal Bupivacaine 13.3 Administered Via a Single Intrathecal Injection to Healthy Volunteers

Healthy

United States
Esfam Biotech Pty Ltd

Not yet recruiting

A Dose Escalation Phase 1 Study Evaluating the Safety and Pharmacokinetics of an Inhaled COVID-19 Inhibitor Delcetravir in Healthy Subjects

COVID-19
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Guangzhou First People's Hospital; Sun Yat-Sen... and other collaborators

Recruiting

G-CSF+DAC+BUCY vs G-CSF+DAC+BF Conditioning Regimen for High-risk MDS Undergoing Allo-HSCT

Myelodysplastic Syndrome | Allogeneic Hematopoietic Stem Cell Transplantation | Conditioning

China
Universidad Nacional de Salta
Fundacion Mundo Sano

Not yet recruiting

Pharmacokinetics and Excretion of Albendazole and Its Metabolites in Saliva

Pharmacological Action
Page B. Pennell, MD
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Physiological-based Pharmacokinetics Approach to Medication Exposure During Pregnancy and Breastfeeding (PBPK)

Epilepsy | Pregnancy Related

United States
AstraZeneca
Parexel

Recruiting

AZD7798 Safety, Tolerability, and Pharmacokinetics After a Single Ascending and Repeat Dose Administrations to Healthy Subjects, and Patients With Crohn's Disease

Healthy Subjects | Crohns Disease

United Kingdom
Dong-A ST Co., Ltd.

Not yet recruiting

Pharmacokinetics and Safety Profiles After Administration of DA-5218 and Co-administration of DA-5218-R1, DA-5218-R2 and DA-5218-R3 in Healthy Adult Volunteers

Healthy

Korea, Republic of
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Guangzhou First People's Hospital; Sun Yat-Sen... and other collaborators

Recruiting

G-CSF+DAC+BUCY vs G-CSF+DAC+BF Conditioning Regimen for Secondary Acute Myeloid Leukemia Undergoing Allo-HSCT

Allogeneic Hematopoietic Stem Cell Transplantation | Conditioning | Secondary Acute Myeloid Leukemia Evolving From MDS

China
Yale University
National Institute on Drug Abuse (NIDA); Aptinyx

Recruiting

Safety, Tolerability and Pharmacokinetics of NYX-783 and Oxycodone DDI Study

Opioid Use Disorder

United States
UNICANCER

Recruiting

TARGETed Therapy Drug MONITOring in DIGestive Oncology (TARGETMONITO)

Metastatic Colorectal Cancer | Hepatocellular Carcinoma | Neuroendocrine Tumors | GIST | Digestive Cancer

France
Kenneth Palmer
United States Department of Defense

Recruiting

Safety, Tolerability, and Pharmacokinetics of Q-Griffithsin Intranasal Spray

COVID-19 Prevention

United States
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Recruiting

Influence of Ethnicity and ABCB1 Gene Polymorphism on the Pharmacokinetics of Azithromycin in Healthy Bangladeshi Volunteers

Comparative Bioavailability Study

Bangladesh
University of California, Los Angeles

Recruiting

Autologous Mobilized Peripheral Blood CD34+ Hematopoietic Stem and Progenitor Cells (HSPC) Transduced With the Elongation Factor Alpha Short Promoter (EFS) - Adenosine Deaminase (ADA) Gene (EFS-ADA) Lentiviral Vector for Adenosine Deaminase Severe Combined Immune Deficiency (ADA SCID)

Adenosine Deaminase Severe Combined Immune Deficiency

United States
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Recruiting

First-in-Human Study to Investigate the Safety and Tolerability and Pharmacokinetics of HS-10383

Cough

China
Sunshine Lake Pharma Co., Ltd.

Recruiting

A Clinical Trial to Evaluate the Pharmacokinetics and Safety of Pyroglutamate Rongliflozin Capsules in Subjects With Mild and Moderate Liver Damage

Diabetes Mellitus, Type 2

China
Idorsia Pharmaceuticals Ltd.

Recruiting

Dose-finding Study Assessing the Efficacy, Safety, and Pharmacokinetics of Daridorexant in Subjects Aged 10 to < 18 Years With Insomnia Disorder

Insomnia

Spain, United States, Belgium, Germany, Bulgaria
National Research Center for Hematology, Russia

Recruiting

RL-MPV Followed by BBC HCT Using Autologous Stem Cells and Maintenance Therapy With Nivolumab for Newly Diagnosed PCNSL

Primary CNS Lymphoma

Russian Federation
Radboud University Medical Center
Sint Maartenskliniek

Not yet recruiting

Periarticular Penetration of Cefazolin and Clindamycin in Second Stage Revision Arthroplasty of the Hip (CONCENTRATE)

Pharmacokinetics | Bone and Joint Infection | PJI
ViiV Healthcare

Recruiting

A Study to Investigate Pharmacokinetics, Safety and Tolerability of Long-Acting Cabotegravir Plus Recombinant Human Hyaluronidase PH20 in Healthy Adult Participants

HIV Infections

United States
Shanghai Synergy Pharmaceutical Sciences Co., Ltd.

Not yet recruiting

Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamic Characteristics of HHT120 in Healthy Subjects (HHT120)

Healthy

China
Chia Tai Tianqing Pharmaceutical Group Nanjing...

Recruiting

A Study of TQH2722 Injection to Evaluate the Safety, Tolerability, Pharmacokinetics, Efficacy and Immunogenicity in Healthy Adult Subjects

Atopic Dermatitis

China
Hanmi Pharmaceutical Company Limited

Not yet recruiting

A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of HCP1904 in Healthy Male Volunteers.

Healthy

Korea, Republic of
Gachon University Gil Medical Center
Yonsei University

Recruiting

Population PK of Antibiotics, Sedative and Analgesics, and Antiplatelet Drugs During ECMO

Extracorporeal Membrane Oxygenation | Pharmacokinetics

Korea, Republic of
argenx

Recruiting

A Clinical Trial to Investigate the Long-term Safety and Tolerability, Efficacy, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of ARGX-117 in Adults With Multifocal Motor Neuropathy (ARDA+)

Multifocal Motor Neuropathy (MMN)

United Kingdom, Spain, United States, Italy, Netherlands, Germany, France, Belgium, Canada, Poland, Austria
Bio-Thera Solutions

Recruiting

Assess Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of BAT8009

Locally Advanced/Metastatic Solid Tumours

China
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

A Study of the Safety, Tolerability, and Pharmacokinetics of Dolutegravir in Neonates Exposed to HIV-1

HIV

United States, Brazil, Puerto Rico, South Africa, Thailand
InDex Pharmaceuticals

Recruiting

Pharmacokinetics of Cobitolimod Enemas in Participants With Active Ulcerative Colitis

Ulcerative Colitis

Sweden
Osijek University Hospital
Josip Juraj Strossmayer University of Osijek

Recruiting

Propofol and Dexmedetomidin vs Midazolam Intraoperative Sedation and POCD (ProDex-POCD)

Postoperative Cognitive Dysfunction | Postoperative Pain, Acute | Pertrochanteric Fracture

Croatia
Eli Lilly and Company

Recruiting

A Single-Ascending and Repeated Dose Study of LY3849891 in Participants With Nonalcoholic Fatty Liver Disease

Non-Alcoholic Fatty Liver Disease

United States, Japan
Region Skane

Recruiting

Pharmacokinetics and Safety of Dexamethasone Eye Drops in Preterm Infants

Retinopathy of Prematurity

Sweden
Ashvattha Therapeutics, Inc.

Recruiting

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of D-4517.2 After Subcutaneous Administration in Subjects With Neovascular (Wet) Age-Related Macular Degeneration (AMD) or Subjects With Diabetic Macular Edema (DME) (Tejas)

Diabetic Macular Edema | Neovascular Age-related Macular Degeneration

United States
Shandong University
Tianjin Central Hospital of Gynecology Obstetrics

Recruiting

Population Pharmacokinetics, Effectiveness and Safety of Cefuroxime in Neonates

Infectious Disease

China
The Affiliated Hospital of Qingdao University
Changzhou Pharmaceutical Factory Co., Ltd

Not yet recruiting

Bioequivalence Study of Ezetimibe Tablets Under Fasting Conditions in Healthy Subjects

Pharmacokinetics | Safety
Astellas Pharma Inc

Recruiting

A Study of ASP3082 in Adults With Previously Treated Solid Tumors

Solid Tumor

United States, Japan
Zhejiang Doer Biologics Co., Ltd.

Recruiting

A First in Human (FIH) Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DR10624

Healthy, Obesity, Metabolically

New Zealand
Cutia Therapeutics（Wuxi）Co.,Ltd

Recruiting

A Phase I Clinical Trial Evaluating the Safety, Tolerability, and Pharmacokinetics of CU-40101 Liniment in Single and Multiple Doses in Adult Male Androgenic Alopecia Subjects

AGA

China
Milton S. Hershey Medical Center

Recruiting

AGN-CognI.Q Acute Dose Safety and Pharmacokinetics Dose-Response in Prostate Cancer Patients

Prostate Cancer

United States
Sunshine Lake Pharma Co., Ltd.

Recruiting

A Study of the Pharmacokinetics, Pharmacodynamics, and Safety of Rongliflozin in Type 2 Diabetic Subjects With Renal Impairment

Type 2 Diabetes

China
Helsinki University Central Hospital
University of Helsinki

Recruiting

KF2019#1-trial: Effects of a Thrombocyte Inhibitor on a Cholesterol-lowering Drug (KF2019#1)

Pharmacokinetics

Finland
Geron Corporation

Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of Imetelstat in Combination With Ruxolitinib in Participants With Myelofibrosis

Myelofibrosis

United States
Centre Hospitalier Intercommunal Creteil

Recruiting

Pharmacokinetics-pharmacodynamics of Morphine With or Without Midazolam Administered by Continuous Infusion in Neonatal Intensive Care

Sedation Complication | Mechanical Ventilation in Neonates

France
Newsoara Biopharma Co., Ltd.

Recruiting

Safety, Tolerance and Pharmacokinetics of THR-1442 in Chinese Healthy Subjects

T2DM (Type 2 Diabetes Mellitus)

China
Apollomics Inc.

Recruiting

A Study Comparing Two Different Capsules, APL-101 and PLB-1001 Capsules, in Healthy Chinese and Caucasian Participants

Bioequivalence

New Zealand
Astellas Pharma Global Development, Inc.

Recruiting

A Study of ASP2138 in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, Pancreatic Cancer

Pancreatic Adenocarcinoma | Gastric Adenocarcinoma | Gastroesophageal Junction (GEJ) Adenocarcinoma

United States, Japan, Korea, Republic of
Hoffmann-La Roche

Recruiting

A Study Evaluating the Efficacy, Safety, and Pharmacokinetics of Glofitamab in Combination With Rituximab Plus Ifosfamide, Carboplatin Etoposide Phosphate in Participants With Relapsed/Refractory Transplant or CAR-T Therapy Eligible Diffuse B-Cell Lymphoma

Diffuse Large B-Cell Lymphoma (DLBCL)

United States
Rutgers, The State University of New Jersey

Recruiting

Preoperative ChemoRadiation And FOLFOXIRI for Rectal Cancer (CRAFTER) for Rectal Cancer

Cancer of Rectum

United States
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

Vincristine Pharmacokinetics in Infants

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm

United States, Australia, Canada
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

Study on Pharmacokinetics of Meperizumab Injection and NUCALA® in Healthy Male Volunteers

Granulomatosis With Polyangiitis | Hemophagocytic Syndrome

China

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