Search clinical trials for: GSK

Total 3946 results

GlaxoSmithKline

Completed

Bioequivalence Study of Paroxetine and PAXIL Under Fasting Conditions in Healthy Mexican Participants

Anxiety Disorders

Mexico
GlaxoSmithKline

Withdrawn

Study to Evaluate Safety, Tolerability and Efficacy of GSK2330811 in Crohn's Disease (COSMIS)

Crohn's Disease | Crohns Disease
GlaxoSmithKline
Merck Sharp & Dohme LLC

Terminated

Letetresgene Autoleucel Engineered T Cells Alone and in Combination With Pembrolizumab in NY-ESO-1 Positive Multiple Myeloma

Neoplasms

United States
GlaxoSmithKline

Completed

Immunogenicity and Safety Study of GSK Biologicals' Herpes Zoster Vaccine GSK1437173A When Co-administered With Prevenar13 in Adults Aged 50 Years and Older

Herpes Zoster

United States, Germany, Estonia, Canada
RemeGen Co., Ltd.

Completed

Evaluation of RC28-E Injection in Wet Age-related Macular Degeneration

Wet Age-Related Macular Degeneration

China
GlaxoSmithKline

Active, not recruiting

A Clinical Study to Evaluate Immune Responses to Rabies Vaccine in Adults Who Received Different Primary Rabies Vaccination Regimens

Virus Diseases

Austria, Germany, Switzerland
Michael Morse, MD
GlaxoSmithKline

Completed

Study to Assess dHER2+AS15 Cancer Vaccine Given in Combination With Lapatinib to Patients With Metastatic Breast Cancer

Metastatic Breast Cancer

United States
GlaxoSmithKline

Completed

Study of Safety, Reactogenicity and Immunogenicity of GlaxoSmithKline's (GSK)Respiratory Syncytial Virus (RSV)Maternal Unadjuvanted Vaccine in Healthy Pregnant Women (Aged 18 to 40 Years) and Their Infants

Respiratory Syncytial Virus Infections

United States, Spain, Canada, Finland, Panama, South Africa, New Zealand, Australia, France
GlaxoSmithKline

Completed

Anemia Studies in Chronic Kidney Disease: Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor Daprodustat-Dialysis (ASCEND-D)

Anaemia | Aspergillosis, Allergic Bronchopulmonary

Australia, Korea, Republic of, Spain, United States, Taiwan, Bulgaria, Mexico, Ukraine, Argentina, Belgium, South Africa, Singapore, Austria, Canada, Netherlands, Russian Federation, Sweden, Turkey, United Kingdom, Germany, Romania and more
GlaxoSmithKline

Completed

A Study to Evaluate the Safety and Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Melrilimab (GSK3772847) in Healthy Participants

Asthma | Healthy Volunteers

United States
GlaxoSmithKline

Completed

Monovalent H5N1 Vaccine GSK1557484A in Children 6 Months to < 18 Years of Age

Influenza | Influenza Vaccines

United States, Thailand, Canada
GlaxoSmithKline

Completed

Study to Evaluate Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Quadrivalent Influenza Vaccine GSK2282512A When Administered to Children 6 to 35 Months of Age

Influenza

Canada, Honduras, Dominican Republic
Novartis Pharmaceuticals

Completed

BRAF/MEK/EGFR Inhibitor Combination Study in Colorectal Cancer (CRC)

Cancer

France, Belgium, Netherlands, United States, Spain, Japan, United Kingdom, Italy
GlaxoSmithKline

Completed

A Study to Evaluate Safety, Reactogenicity and Immunogenicity of GSK Biologicals' RSV Investigational Vaccine Based on Viral Proteins Encoded by Chimpanzee-derived Adenovector (ChAd155-RSV) (GSK3389245A) in RSV-seropositive Infants

Respiratory Syncytial Virus Infections

Taiwan, Spain, United States, Italy, Canada, Panama, Mexico, Poland
ViiV Healthcare

Terminated

Evaluation of the Safety, Tolerability and Pharmacokinetics (PK) of GSK3732394 First-Time-in-Human (FTIH) Study

HIV Infections

United States
ViiV Healthcare

Completed

Rapid Test and Treat Dolutegravir Plus Lamivudine Study in Newly Diagnosed Human Immunodeficiency Virus (HIV)-1 Infected Adults

HIV Infections

United States
Theravance Biopharma
GlaxoSmithKline

Completed

An Investigation Of The Interaction Of GSK961081 With Inhaled Beta-Agonist And Anti-Muscarinic Drugs.

Pulmonary Disease, Chronic Obstructive

Thailand, New Zealand, United Kingdom
Respirent Pharmaceuticals Co Ltd.
Becro Ltd.

Active, not recruiting

Bioequivalence Study of Fluticasone Propionate 250 mcg and Salmeterol Xinafoate 50 mcg Inhalation Powder/Respirent Pharmaceuticals vs. ADVAIR DISKUS® 250/50 Inhalation Powder/GSK in Healthy Volunteers

Asthma | Bioequivalence

Greece
Sanford Research
GlaxoSmithKline

Completed

Effects of Lovaza on Lipoprotein Composition and Function in Mild Hypertriglyceridemia (ELLF)

Hypertriglyceridemia

United States
GlaxoSmithKline

Completed

Anemia Studies in Chronic Kidney Disease (CKD): Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat-in Incident Dialysis (ASCEND-ID)

Anaemia

United States, Korea, Republic of, Argentina, Spain, Australia, Canada, Russian Federation, United Kingdom, Malaysia, Italy, Poland, Germany, India, Mexico, South Africa
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety, Tolerability, and Pharmacokinetics of an Investigational, Injectable HIV Medicine (GSK1265744) in HIV-Uninfected Adults

HIV Infections

United States, Malawi, Brazil, South Africa
University Hospital Plymouth NHS Trust
University of Plymouth

Completed

Simvastatin as a Neuroprotective Treatment for Moderate Parkinson's Disease (PD STAT)

Parkinson Disease

United Kingdom
Theravance Biopharma
GlaxoSmithKline

Completed

Succinate Salt Version of GSK961081 for Healthy Volunteers

Pulmonary Disease, Chronic Obstructive

United Kingdom
Theravance Biopharma
GlaxoSmithKline

Completed

A Study to Investigate the Pharmacology of a Dual Pharmacophore in Healthy Volunteers

Pulmonary Disease, Chronic Obstructive

United Kingdom
Theravance Biopharma
GlaxoSmithKline

Completed

Study of GSK961081 in Healthy Volunteer Subjects

Pulmonary Disease, Chronic Obstructive

United Kingdom
Theravance Biopharma
GlaxoSmithKline; Hammersmith Medicines Research

Completed

A Phase 1 (Ph1), Single Dose (SD), GSK961081 Absorption, Distribution, Metabolism, and Excretion (ADME) Study in Healthy Subjects

Pulmonary Disease, Chronic Obstructive

United Kingdom
Pfizer

Completed

Immunogenicity and Safety Study of 1 and 2 Doses of GlaxoSmithKline (GSK) Biologicals' Meningococcal Vaccine MenACWY-TT (GSK134612) in Toddlers, Persistence up to 5 Years After Vaccination and Co-administration With Pfizer's Prevenar 13™Vaccine

Infections, Meningococcal

Australia, Canada, Czechia, Panama, South Africa, Turkey
GlaxoSmithKline

Completed

Immunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Given at 6, 7.5 and 9 Months of Age in Co-administration With Measles, Rubella and Yellow Fever (YF) Vaccines Followed by a Booster of the Malaria Vaccine.

Malaria | Malaria Vaccines

Ghana
ViiV Healthcare

Completed

Low-dose Fostemsavir Extended Release Relative Bioavailability Study

HIV Infections

United States
Atlanta VA Medical Center
University of Alabama at Birmingham; Emory University

Completed

Behavior and Exercise Versus Drug Treatment in Men With Nocturia (BEDTiMe) (BEDTiMe)

Nocturia

United States
GlaxoSmithKline

Completed

A Post Marketing Surveillance (PMS) Study to Monitor the Safety of GlaxoSmithKline (GSK) Biologicals' Human Papillomavirus (HPV) Vaccine in Female Chinese Subjects

Cervical Intraepithelial Neoplasia

China
Human Genome Sciences Inc., a GSK Company
GlaxoSmithKline

Completed

Efficacy and Safety of Belimumab in Black Race Patients With Systemic Lupus Erythematosus (SLE) (EMBRACE)

Systemic Lupus Erythematosus

United States, South Africa, France, United Kingdom, Brazil, Colombia
GlaxoSmithKline

Completed

A Study to Evaluate the Safety, Efficacy and Changes in Induced Sputum and Blood Biomarkers Following Daily Repeat Doses of Inhaled GSK2269557 in Chronic Obstructive Pulmonary Disease (COPD) Subjects With Acute Exacerbation

Pulmonary Disease, Chronic Obstructive

Canada, Denmark
GlaxoSmithKline

Completed

To Evaluate Oral Health and Quality of Life Associated With Use of a Denture Adhesive

Denture Retention

Canada
GlaxoSmithKline

Completed

Letetresgene Autoleucel Engineered T Cells in NY-ESO -1 Positive Advanced Non-Small Cell Lung Cancer (NSCLC)

Neoplasms

United States
GlaxoSmithKline

Completed

A Study to Test if a Third Dose of the Vaccine is Safe in Current and Former Smokers Aged 40 to 80 Years Old and to Gather Information on the Immune Response Following the Third Dose of the Vaccine

Respiratory Disorders

Germany, Canada, United Kingdom
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Ofatumumab in Treating Patients With Previously Untreated Stage II, Stage III, or Stage IV Follicular Non-Hodgkin Lymphoma

Lymphoma

United States
GlaxoSmithKline
Quotient Clinical

Completed

A Study to Compare the Pharmacokinetics (PK) of GSK2982772 Following Administration of Different Modified Release (MR) Formulations in Capsule and MR Tablet Formulations Relative to an Immediate Release (IR) Tablet Formulation and to Check the PK of MR Formulation in Capsule Following Repeat Doses

Autoimmune Diseases

United Kingdom
GlaxoSmithKline

Completed

A Photoxicity and Photoallergy Study of a Developmental Face Cream, Serum and Lotion

Skin Care

Brazil
GlaxoSmithKline

Completed

A Study to Evaluate Different Dose Levels of GlaxoSmithKline (GSK) Biologicals' Investigational Respiratory Syncytial Virus (RSV) Vaccine (GSK3888550A), Based on the Vaccine Safety and the Antibodies (Body Defences) Produced Following Vaccine Administration, When Given to Healthy Non-pregnant Women

Respiratory Syncytial Virus Infections

United States, Germany, Finland
GlaxoSmithKline
Novartis Vaccines

Completed

Study to Evaluate Long Term Immunogenicity up to 10 Years After the First Booster Immunization With Tick Borne Encephalitis Vaccine in Adults Who Received 1 of 3 Different Primary Vaccination Schedules

Virus Diseases | Tick Borne Encephalitis

Czechia
GlaxoSmithKline

Completed

An Efficacy Study of GSK2269557 Added to Standard Care in Subjects With an Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

Romania, Russian Federation, Belgium, Denmark, Netherlands
University of Dundee
University of Oxford

Completed

Evaluation of Lithium as a Glycogen-Synthase-Kinase-3 (GSK-3) Inhibitor in Mild Cognitive Impairment

Mild Cognitive Impairment
GlaxoSmithKline
Bristol-Myers Squibb; CRF health

Completed

Effect of Mepolizumab in Severe Bilateral Nasal Polyps

Nasal Polyps

Australia, United States, Argentina, Netherlands, Russian Federation, Sweden, Germany, Korea, Republic of, United Kingdom, Canada, Romania
Charite University, Berlin, Germany

Completed

Sunphenon Epigallocatechin-Gallate (EGCg) in Duchenne Muscular Dystrophy (SUNIMUD)

Duchenne Muscular Dystrophy

Germany
Concordia University, Montreal

Completed

Therapy With an Oxytocin Adjunct for Major Depression (TOAD2015)

Depressive Disorder

Canada
GlaxoSmithKline

Completed

RELVAR® 100 ELLIPTA® Special Drug Use Investigation (COPD, Long-term)

Pulmonary Disease, Chronic Obstructive

Japan
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Ofatumumab as Front-Line Therapy in Treating Elderly Participants With Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

United States
GlaxoSmithKline

Completed

Dose Response of 28 Days of Dosing of GSK962040 in Type I and II Diabetic Male and Female Subjects With Gastroparesis

Gastroparesis

United States, Australia, Belgium, United Kingdom, Canada, Sweden
GlaxoSmithKline
Parexel

Completed

A Comparative Study Between Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) Single Inhaler Triple Therapy Versus Tiotropium Monotherapy in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Poland, United States, Russian Federation

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