Clinical Trials Sponsored by Philogen S.p.A.

Total 670 results

Philogen S.p.A.

Recruiting

A Study Comparing the Efficacy of L19TNF+Doxorubicin vs Doxorubicin Alone as First-line Therapy in Patients With Advanced or Metastatic Soft Tissue Sarcoma (FIBROSARC)

Soft Tissue Sarcoma

Spain, Germany, France, Italy, Poland
Philogen S.p.A.

Active, not recruiting

Dose Finding Study of L19TNF and Doxorubicin in Patients With STS (DOXO75)

Soft Tissue Sarcoma

United States
Philogen S.p.A.

Terminated

A Randomized, Placebo-controlled Phase II Clinical Trial to Evaluate the Safety and Efficacy of F8IL10 (Dekavil) in Patients With Active RA Receiving MTX

Rheumatoid Arthritis

Switzerland, Germany, Italy
Philogen S.p.A.

Active, not recruiting

F16IL2 in Combination With Nivolumab in Patients With Non-small Cell Lung Cancer (Nivokin)

Non-small Cell Lung Cancer (NSCLC)

Switzerland
Philogen S.p.A.

Terminated

Combination Therapy of L19IL2 and Gemcitabine in Advanced Pancreatic Cancer Patients

Pancreatic Cancer Patients Diagnosed With Locally Advanced or Metastatic Pancreatic Cancer Not Amenable to Curative Surgical Resection

Italy, Germany
Philogen S.p.A.

Completed

Combination Therapy of F16IL2 and Paclitaxel in Solid Tumour Patients

Breast Cancer | Solid Tumor | Metastatic Melanoma | Non-small Cell Lung Cancer (NSCLC)

Italy
Philogen S.p.A.

Completed

Intratumoral Administration of L19IL2/L19TNF

Malignant Melanoma, Skin

Italy
Philogen S.p.A.

Terminated

131I-L19SIP Radioimmunotherapy Combined With Radiochemotherapy in Patients With Locally-advanced Non Small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer

Italy
Philogen S.p.A.

Not yet recruiting

A Study With L19TNF in Combination With Lomustine in Patients With Glioblastoma at Progression or Recurrence (GLIOSTELLA)

Glioblastoma
Philogen S.p.A.

Recruiting

Efficacy and Safety of L19TNF in Previously Treated Patients With Advanced Stage or Metastatic Soft-tissue Sarcoma (FLASH)

Soft Tissue Sarcoma

France, Spain, Germany, Italy, Poland
Philogen S.p.A.

Recruiting

Intratumoral Administration of Daromun in Non-melanoma Skin Cancer Patients (DUNCAN)

Carcinoma, Basal Cell | Carcinoma, Cutaneous Squamous Cell

Germany, Poland, Switzerland
Philogen S.p.A.

Recruiting

Treatment of Metastatic Soft Tissue Sarcoma (STS) Patients (FIBROSARC USA) (FIBROSARC US)

Leiomyosarcoma

United States
Philogen S.p.A.

Recruiting

Neoadjuvant L19IL2/L19TNF- Pivotal Study (Pivotal)

Malignant Melanoma

Italy, France, Germany, Poland
Philogen S.p.A.

Completed

Safety and Efficacy of L19TNF in Patients With Isocitrate Dehydrogenase (IDH) Wildtype WHO Grade III / IV Glioma at First Relapse (GLIOMOON)

Glioma of Brain

Switzerland
Philogen S.p.A.

Completed

Combination Therapy of F8IL10 and Methotrexate in Rheumatoid Arthritis Patients

Rheumatoid Arthritis

Italy
Philogen S.p.A.

Terminated

Combination Therapy of F16IL2 and Doxorubicin in Solid Tumour Patients

Breast Cancer | Advanced Solid Tumor

Italy
Philogen S.p.A.

Recruiting

A Study to Evaluate the Safety and Dosimetry of 68Ga-labelled OncoFAP Derivatives in Solid Tumors (FAPrimo)

Breast Cancer | Colorectal Cancer | Pancreas Adenocarcinoma | Oesophageal Cancer

Italy
Philogen S.p.A.

Not yet recruiting

Safety and Preliminary Signs of Efficacy of F8IL10 for Intra-articular Treatment (DekaJoint)

Rheumatoid Arthritis
Philogen S.p.A.

Recruiting

L19IL2/L19TNF in Skin Cancer Patients (IntriNSiC)

Kaposi Sarcoma | Merkel Cell Carcinoma | BCC - Basal Cell Carcinoma | SCC - Squamous Cell Carcinoma | Keratoacanthoma of Skin | Malignant Adnexal Tumors of the Skin (MATS) | Tumors From Cutaneous T-cell Lymphoma (CTCL)

Spain, France, Italy
Philogen S.p.A.

Recruiting

A Study to Evaluate Safety and Efficacy of L19TNF Plus Lomustine in Patients With Glioblastoma at First Progression (GLIOSTAR)

Glioblastoma

France, Germany, Italy, Switzerland
Philogen S.p.A.

Recruiting

Safety and Early Signs of Efficacy of IL12-L19L19. (DODEKA)

Advanced Solid Tumor | Metastatic Solid Tumor

Italy, Germany, Switzerland
Philogen S.p.A.

Recruiting

Safety and Efficacy of L19TNF Plus Temozolomide Chemoradiotherapy in Patients With Newly Diagnosed Glioblastoma (GLIOSUN)

Glioblastoma

Switzerland
Philogen S.p.A.

Recruiting

Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C Melanoma Patients (NeoDREAM)

Melanoma Stage IIIB/C

Spain, United States, Switzerland
Philogen S.p.A.

Withdrawn

Safety and Efficacy of Different Administration Sequences of L19TNF With Lomustine in Glioblastoma at First Progression (GLIOASTRA)

Glioblastoma
Philogen S.p.A.

Terminated

A Phase I/II Study of the Tumor-targeting Human L19-IL2 Monoclonal Antibody-cytokine Fusion Protein in Combination With Rituximab in Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)

Diffuse Large B-cell Lymphoma (DLBCL)

Germany
Philogen S.p.A.

Terminated

A Study of the Tumor-targeting Human F16IL2 Monoclonal Antibody-cytokine Fusion Protein in Combination With Very Low-dose Cytarabine in Patients With AML Relapse After Allogeneic Hematopoietic Stem Cell Transplantation

Acute Myeloid Leukemia, Relapsed, Adult

Germany
Philogen S.p.A.

Active, not recruiting

A Phase I/II Dose Escalation Study of the Tumor-targeting Human L19-IL2 Monoclonal Antibody-cytokine Fusion Protein in Combination With Dacarbazine for Patients With Metastatic Melanoma

Metastatic Melanoma Stage IV

Italy, Germany
Philogen S.p.A.

Completed

L19TNFα in Combination With Doxorubicin in Patients With Advanced Solid Tumours

Advanced Solid Tumors Amenable to Anthracycline Therapy | Sarcoma, Breast Cancer, Lung Carcinomas, and Gynecological Cancer Amenable to Anthracycline Therapy

Germany, Italy
Philogen S.p.A.

Completed

Intratumoral Application of L19IL2 in Patients With Malignant Melanoma

Malignant Melanoma

Austria, Germany
Philogen S.p.A.

Completed

131I-L19SIP Radioimmunotherapy (RIT) in Combination With External Beam Radiation in Patients With Multiple Brain Metastases From Solid Tumors

Brain Metastases From Solid Tumors

Italy, United Kingdom
Philogen S.p.A.

Terminated

Radioimmunotherapy With 131I-L19SIP in Patients With Cancer

Patients With Cancer

Italy, United Kingdom
Philogen S.p.A.
Boehringer Ingelheim

Completed

Trial to Find and Investigate a Safe Dose of F16IL2 and BI 836858 in Patients With AML Relapse After Allogeneic Hematopoietic Stem Cell Transplantation (PHIBI)

Acute Myeloid Leukemia (AML) Relapse

Germany
Philogen S.p.A.
Eudax S.r.l.

Completed

A Dose Finding and Efficacy Study of the Tumour Targeting Human 131I-F16SIP Monoclonal Antibody in Patients With Cancer

Cancer

Italy
Philogen S.p.A.
Syneos Health

Completed

A Dose Finding Pharmacokinetic Study of the Tumour-targeting Human L19IL2 Monoclonal Antibody-Cytokine Fusion Protein in Patients With Advanced Solid Tumours

Advanced Solid Tumours

Italy, Germany
Philogen S.p.A.
Eudax S.r.l.

Terminated

Clinical Study Phase II of L19IL2 in Combination With Dacarbazine in Patients With Metastatic Melanoma

Metastatic Melanoma

Switzerland, Italy, Austria, Germany
Philogen S.p.A.
Immatics Biotechnologies GmbH

Terminated

F16IL2 Plus Paclitaxel in Metastatic Merkel Cell Carcinoma

Merkel Cell Carcinoma

Germany, Austria, Denmark, France, Spain, United Kingdom
Philogen S.p.A.
Eudax S.r.l.; InnoPharma Inc.

Completed

Phase 1 Dose-finding Study of L19TNFα Plus Melphalan Using Isolated Inferior Limb Perfusion (ILP) in Subjects With Intransit Stage III/IV Melanoma

Patients With Intransit Stage III/IV Melanoma

Italy
Philogen S.p.A.
Merck Sharp & Dohme LLC

Active, not recruiting

Study of the Efficacy of Intratumoral L19IL2 or L19TNF or L19IL2/L19TNF, in Combination With Pembrolizumab, in Unresectable Melanoma Patients (INTACT/MeRCI)

Melanoma Stage IV | Melanoma Stage III

United States
Philogen S.p.A.
Eudax S.r.l.; InnoPharma Inc.

Completed

L19TNFα in Patients With Advanced Solid Tumors

Colorectal Cancer | Solid Tumors

Italy
Pollogen

Completed

Evaluation of Safety and Efficacy of the 3F Applicator (A3F) for Treatment of Facial Wrinkles

Facial Wrinkles

United States
Pollogen

Unknown

Evaluation of Safety and Efficacy of TriPollar Device for Treatment of Wrinkles

Facial Wrinkles

United States
Pollogen

Completed

Evaluation of Safety and Efficacy of the Apollo™ System for Treatment of Wrinkles and Rhytides

Facelift

United States, Israel
Tethis S.p.A.

Recruiting

Evaluation of See.d as an Automated Blood Sample Preparator for Multiple Liquid Biopsy Applications

Breast Cancer | Healthy Participants

Italy
Tethis S.p.A.

Recruiting

Feasibility Study Aiming at Pre-Analytical Standardization of Whole Blood Processing for Liquid Biopsy Applications

Healthy Participants

Italy
Limacorporate S.p.a

Recruiting

H-35 CL TRAUMA Cemented Femoral Stem

Arthroplasty | Hip | Replacement

Italy
SOFAR S.p.A.

Not yet recruiting

Evaluation Of The Effect Of L. Casei DG® On Vitamin D Absorption In Patients Under Vitamin D Supplementation.

Vitamin D Deficiency

United Arab Emirates
Limacorporate S.p.a

Recruiting

S-33 SMR Shoulder HP Reverse Glenosphere

Arthroplasty, Replacement, Shoulder

United Kingdom
Limacorporate S.p.a

Recruiting

Multigen Plus CCK and AMF TT Cones Follow Up Study

Total Knee Arthroplasty | Revision Total Knee Arthroplasty

United Kingdom, Portugal, Slovakia
Tethis S.p.A.

Recruiting

Identification of Breast Cancer Specific Markers in Patients Compared to Healthy Participants

Breast Neoplasms

Italy
Limacorporate S.p.a

Recruiting

H-29 DELTA Multihole TT Study.

Osteoarthritis, Hip

Poland

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