Search clinical trials for: HCL

Total 1905 results

Hospices Civils de Lyon

Completed

Relationship Between Degree of Domestic Environmental Fungal Exposure and Clinical Symptoms of Patients With Chronic Obstructive Pulmonary Disease (BPCO-Myc)

Chronic Obstructive Pulmonary Disease

France
University Hospital, Bordeaux

Completed

Hair Cortisol and Cushing's Disease (HAIRCUSH)

Cushing Disease

France
Albert Einstein College of Medicine
National Cancer Institute (NCI)

Active, not recruiting

Chemotherapy Before Surgery and Tissue Sample Collection in Patients With Stage IIA-IIIC Breast Cancer

Stage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer | Stage IIIC Breast Cancer

United States
Memorial Sloan Kettering Cancer Center
City of Hope Medical Center; Stanford University; University of Rochester; Seagen...

Active, not recruiting

Brentuximab Vedotin Combined With AVD Chemotherapy in Patients With Newly Diagnosed Early Stage, Unfavorable Risk Hodgkin Lymphoma

Hodgkin Lymphoma

United States
AbbVie

Completed

A Phase 2 Study of ABBV-3067 Alone and in Combination With ABBV-2222

Cystic Fibrosis

United States, Belgium, Canada, Czechia, France, Hungary, Netherlands, New Zealand, Poland, Slovakia, United Kingdom, Serbia
AbbVie

Active, not recruiting

Assessing Effectiveness of Adalimumab for Treating Ulcerative Colitis in Real Life Conditions (SOTHIS)

Ulcerative Colitis (UC)

France
Sunovion

Completed

Efficacy and Safety of Levalbuterol in Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

United States, Canada
Janssen Research & Development, LLC

Completed

A Study to Explore the Efficacy of JNJ-67953964 in the Treatment of Depression

Depressive Disorder, Major

United States, Germany, Moldova, Republic of, Russian Federation, Ukraine, United Kingdom
Eisai Inc.
PPD; Covance; Quest Pharmaceutical Services

Terminated

A Study of AQUAVAN® Injection Versus Midazolam HCl for Sedation in Elderly Patients Undergoing Elective Colonoscopy

Colonoscopy | Colon Polyps
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins University; Massachusetts General Hospital; National Institute... and other collaborators

Completed

Buspirone for Early Satiety and Symptoms of Gastroparesis (BESST)

Gastroparesis

United States
Bozyaka Training and Research Hospital

Completed

Comparison of Different Approaches for Supraclavicular Block and Their Effects on Diaphragm Muscle Function

Complications | Brachial Plexus Block | Respiratory Complication | Nerve Block | Phrenic Nerve Paralysis | Diaphragm Sellae Meningioma

Turkey
Heron Therapeutics

Completed

HTX-011 in Spinal Surgery

Lumbar Laminectomy | Post-Operative Pain

United States
Centre Hospitalier Universitaire de Saint Etienne
Sanofi Pasteur, a Sanofi Company; Bioster, a.s.

Completed

Factors Influencing the COVID-19 Vaccine Immune Response According to Age and Presence or Not of a Past History of COVID-19 (COVIMMUNAGE)

Covid19

France
Children's Oncology Group
National Cancer Institute (NCI); University College, London; Medical Research...

Completed

Combination Chemotherapy, PEG-Interferon Alfa-2b, and Surgery in Treating Patients With Osteosarcoma (EURAMOS-1)

Metastatic Osteosarcoma | Localized Osteosarcoma

United States, Canada, Australia, New Zealand, Puerto Rico, Switzerland
Heron Therapeutics

Withdrawn

Pediatric Postoperative Analgesia Herniorrhaphy Study

Analgesia

United States
Northwestern University
National Cancer Institute (NCI); Merck Sharp & Dohme LLC

Active, not recruiting

PET-Directed Therapy With Pembrolizumab and Combination Chemotherapy in Treating Patients With Previously Untreated Classical Hodgkin Lymphoma

Classical Hodgkin Lymphoma | Lymphocyte-Depleted Classical Hodgkin Lymphoma | Lymphocyte-Rich Classical Hodgkin Lymphoma | Mixed Cellularity Classical Hodgkin Lymphoma | Nodular Sclerosis Classical Hodgkin Lymphoma

United States
Centre Hospitalier Universitaire de Saint Etienne

Completed

Corneal Toxicity in Patients Treated by Belantamab Mafodotin

Myeloma Multiple

France
BioMérieux
Vanderbilt University Medical Center; Centre d'Investigation Clinique - Limoges

Completed

Early Identification of SEPsis SIGNs in Emergency Department (SepSIGN)

Sepsis | Infection

United States, Monaco, France
Monopar Therapeutics

Terminated

Clonidine HCl MBT vs. Placebo to Prevent Chemoradiotherapy-Induced Severe Oral Mucositis in Oropharyngeal Cancer. (VOICE)

Chemoradiotherapy-Induced Severe Oral Mucositis

United States, Spain, Germany, France, Puerto Rico
Mayo Clinic
National Cancer Institute (NCI)

Completed

Daunorubicin Hydrochloride, Cytarabine, and Nilotinib in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Untreated Adult Acute Myeloid Leukemia

United States
Teva Pharmaceuticals USA

Completed

Terbinafine HCl 250 mg Tablet Formulations Under Non-Fasting Conditions

Healthy

United States
Intergroupe Francophone de Cancerologie Thoracique
Bristol-Myers Squibb

Completed

Cohort of Patients With NSCLC Treated With Nivolumab Under the ATU Program (CLINIVO)

Non-small Cell Lung Cancer | Nivolumab | Long-term Adverse Effects

France
Intergroupe Francophone de Cancerologie Thoracique

Completed

French Biological Observatory on Lung Cancer in Never Smokers (BioCAST)

Lung Cancer

France
Teva Pharmaceuticals USA

Completed

Benazepril HCl 40 mg Tablets, Fed

Healthy

United States
Washington State University
National Center for Complementary and Integrative Health (NCCIH)

Active, not recruiting

Clinical Evaluation of the Pharmacokinetic Goldenseal-Metformin Interaction in Diabetic Patients

Diabetes Mellitus, Type 2 | Interaction, Adverse Herb-Drug

United States
Huda Fahmy Mahmoud, PhD

Completed

Ketamine Versus Dexmedetomidine for Prevention of Postoperative Delirium

Emergence Delirium

Egypt
Medtronic - MITG

Terminated

ProGripTM Self-Gripping Polyester Mesh in Incisional Hernia Prevention (POETRY)

Incisional Hernia

France
Mayo Clinic
National Cancer Institute (NCI)

Completed

Avatar-Directed Chemotherapy in Treating Patients With Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma

United States
AstraZeneca
Iqvia Pty Ltd

Terminated

US Post-Marketing Safety Study of Moxetumomab Pasudotox-tdfk (LUMOXITI) (PROXY)

Hairy Cell Leukemia

United States
University of South Florida

Completed

Minocycline in the Treatment of Angelman Syndrome

Angelman Syndrome

United States
Indivior Inc.
Reckitt Benckiser LLC

Completed

Study of Two Formulations of Buprenorphine HCl in Opioid-dependent Subjects on Buprenorphine Maintenance Therapy (Study P04451) (COMPLETED)

Opioid Dependency
AbbVie

Completed

A Study to Evaluate Long-term Outcomes Following Treatment With ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 With or Without Ribavirin (RBV) in Adults With Genotype 1 Chronic Hepatitis C Virus (HCV) Infection (TOPAZ-I)

Chronic Hepatitis C Virus (HCV) Infection Genotype 1

Algeria, Australia, Belgium, Bulgaria, Canada, Denmark, Finland, France, Germany, Greece, Israel, Italy, Mexico, Netherlands, Norway, Poland, Portugal, Romania, Russian Federation, Saudi Arabia, Spain, Switzerland, Turkey, Austria, Ireland and more
Helsinn Healthcare SA

Completed

A Study to Evaluate the Efficacy and Safety of Anamorelin HCl for the Treatment of Malignancy Associated Weight Loss and Anorexia in Adult Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer | Cachexia; Cancer

United States, Russian Federation, Bulgaria, Hungary, Italy, Romania, Serbia
Helsinn Healthcare SA

Completed

A Study to Evaluate the Efficacy and Safety of Anamorelin HCl for the Treatment of Malignancy Associated Weight Loss and Anorexia in Adult Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer | Cachexia; Cancer

United States, Croatia, Australia, Belgium, Russian Federation, Poland, Romania, Ukraine
Genuine Research Center, Egypt
Eva Pharma

Completed

Bioequivalence Study of of Metformin HCl From Gleptomet 50/1000 mg F.C.Tablets (EVA Pharma, Egypt) and Janumet 50/1000 mg F.C.Tablets (Merck Sharp & Dohme, The Netherlands)

Healthy

Egypt
National Cancer Institute (NCI)

Completed

Dasatinib Followed by Stem Cell Transplant in Treating Older Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1

United States
Mario Negri Institute for Pharmacological Research
Fondazione Telethon

Completed

Familiar Fatal Insomnia: Preventive Treatment With Doxycycline in Subject With Disease Risk (FFI)

Familial Fatal Insomnia
Radboud University Medical Center

Active, not recruiting

Efficacy of Diltiazem to Improve Coronary Microvascular Dysfunction: a Randomized Clinical Trial (EDIT-CMD)

Coronary Vasospasm | Microvascular Angina | Microvascular Ischemia of Myocardium

Netherlands
Rutgers, The State University of New Jersey
National Cancer Institute (NCI); Rutgers Cancer Institute of New Jersey

Active, not recruiting

Pegylated Liposomal Doxorubicin Hydrochloride and Carboplatin Followed by Surgery and Paclitaxel in Treating Patients With Triple Negative Stage II-III Breast Cancer

Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Triple-negative Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer | Stage IIIC Breast Cancer | Estrogen Receptor-negative Breast Cancer | Progesterone Receptor-negative Breast Cancer | HER2-negative Breast Cancer

United States
Nepal Mediciti Hospital

Completed

Comparison of the Time to the First Rescue Analgesic Among Parturients Receiving Intrathecal Additive Fentanyl or Intrathecal Fentanyl With TAP Block or TAP Block Alone for Elective Cesarean Sections Under Hyperbaric Bupivacaine Spinal Anesthesia

Postoperative Pain | Cesarean Section

Nepal
CHU de Quebec-Universite Laval
Purdue Pharma LP; Équipe de Recherche Michel-Sarrazin en Oncologie psychosociale... and other collaborators

Terminated

Effect of Methylphenidate on Cancer-related Cognitive Impairment (CogMet)

Breast Cancer Female | Cancer-Related Condition

Canada
Beth Israel Deaconess Medical Center

Active, not recruiting

Lorcaserin in Obesity: Identification of CNS Targets Using fMRI

Obesity | Weight Loss

United States
Allergan

Completed

A Study to Assess Safety and Efficacy in Participants Age 40 to 55 With Presbyopia (Old Eye) Who Receive AGN-190584 in Both Eyes Twice Daily (Virgo)

Presbyopia

United States
Assistance Publique Hopitaux De Marseille

Completed

Open Lung Protective Ventilation in Cardiac Surgery (PROVECS)

Hypoxemia

France
Shanghai Hengrui Pharmaceutical Co., Ltd.

Completed

A Trial of HR18034 for Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy.

Postsurgical Pain Management

China
Hospices Civils de Lyon

Completed

Stereotactic Radiotherapy for Renal Cancers (RSR-1)

Renal Cancer

France
Intergroupe Francophone de Cancerologie Thoracique

Completed

Chemotherapy for Lung Cancer in HIV-positive Patients (CHIVA)

Non-small Cell Lung Cancer | Hiv-positive

France
Intergroupe Francophone de Cancerologie Thoracique
University Hospital, Caen; Groupe Français de Pneumo-Cancérologie

Completed

Mesothelioma Avastin Plus Pemetrexed-cisplatin Study (MAPS)

Mesothelioma

France
Intergroupe Francophone de Cancerologie Thoracique

Completed

Re-introduction of Pemetrexed and Cisplatin With Prolonged Angiogenic Blocking by Bevacizumab in Advanced Lung Cancer. (BUCiL)

Nonsquamous Nonsmall Cell Neoplasm of Lung | Non-small Cell Lung Cancer Metastatic

France
AbbVie

Terminated

Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) Lemzoparlimab With or Without Oral/IV Dexamethasone and in Combination With Oral/IV/Subcutaneous Anti-Myeloma Regimens in Adult Participants With Multiple Myeloma

Multiple Myeloma

United States, Australia, France, Germany, Israel, Japan, Spain

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