Search clinical trials for: Notch Pathway

Total 1473 results

xCures
Cancer Commons

Available

Expanded Access to Ulixertinib (BVD-523) in Patients With Advanced MAPK Pathway-Altered Malignancies

Melanoma | Head and Neck Cancer | Glioblastoma | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Small Bowel Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Cholangiocarcinoma | Bladder Cancer | Thyroid Cancer | ERK Mutation | MAPK Gene Mutation | KRAS Activating... and other conditions

United States
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; Queen's Medical Center; The Rotherham NHS Foundation... and other collaborators

Completed

Breakfast Group Interventions in Stroke Rehabilitation (BISTRo)

Stroke

United Kingdom
Birmingham Women's and Children's NHS Foundation...
Tommy's

Completed

The HYsteroscopic Miscarriage MaNagement Trial: A Pilot RCT Investigating a Novel Management Pathway for RPOC (HYMMN)

Retained Products After Miscarriage

United Kingdom
YaNi Peng

Completed

Exploration of New Nursing Models for Urological Surgery

Urological Nursing

China
Chiesi UK
Gesellschaft für Therapieforschung mbH

Active, not recruiting

A Trial Monitoring Therapy Pathways of Asthma Patients Treated With an Extrafine ICS/LABA/LAMA Single-inhaler Triple Therapy in a Real-world Setting and Characterizing the Effects on Health-related Out-comes (TriMaximize)

Asthma

United Kingdom
Rennes University Hospital
Institut NuMeCan, INRAE 1341

Completed

Functional Magnetic Resonance Imaging (fMRI) Exploration of Neurocognitive Processes Involved in Food Addiction (FA) in Obese Patients: Towards New Phenotypic Markers for an Optimized Care Pathway (AddictO)

Obesity

France
University Health Network, Toronto
Boehringer Ingelheim

Completed

A Study of Afatinib in Patients With Advanced Cancer With Changes in the HER Gene

Solid Tumors

Canada
Erasca, Inc.

Completed

A Study of Anti-Cancer Therapies Targeting the MAPK Pathway in Patients With Advanced NSCLC (HERKULES-2)

Advanced Non-squamous Non-small-cell Lung Cancer

United States
University of Alabama, Tuscaloosa
University of Alabama at Birmingham; Tuscaloosa Veterans Affairs Medical Center

Completed

Minds and Mentors Program (MiMP)- R61 (MiMP)

Substance Use Disorders | Medication Assisted Treatment | Opioid-use Disorder

United States
Cardiff and Vale University Health Board
The Leeds Teaching Hospitals NHS Trust; University of Leeds; University Hospital... and other collaborators

Active, not recruiting

Pathway of Low Anterior Resection Syndrome Relief After Surgery: a Feasibility Study (POLARiS)

Low Anterior Resection Syndrome

United Kingdom
Alexandria University

Completed

Evaluation of Diode Laser and Topical Steroid Therapy in the Treatment of Erosive Oral Lichen Planus

Erosive Oral Lichen Planus

Egypt
University of Cologne

Completed

Analysis of Mother-child Interaction and Regulation of Candidate Genes of Stress Signaling Pathways in Mature Infants

Mother-Child Interaction

Germany
M.D. Anderson Cancer Center

Terminated

Single-arm Study With Bimiralisib in Patients With HNSCC Harboring NOTCH1 Loss of Function Mutations (HNSCC)

HNSCC

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Terminated

Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors

Sarcoma | Lymphoma | Kidney Cancer | Unspecified Childhood Solid Tumor, Protocol Specific | Testicular Germ Cell Tumor | Ovarian Cancer | Brain and Central Nervous System Tumors | Neuroblastoma | Liver Cancer | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

United States
Leap Therapeutics, Inc.

Completed

A Study of DKN-01 as a Monotherapy or in Combination With Paclitaxel in Patients With Recurrent Epithelial Endometrial or Epithelial Ovarian Cancer or Carcinosarcoma (P204)

Ovarian Cancer | Carcinosarcoma | Endometrial Cancer | Uterine Cancer

United States
University of Wisconsin, Madison
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Pathways for Parents After Incarceration Feasibility Study

Parenting | Behavior | Development, Child

United States
Novartis Pharmaceuticals

Terminated

Study Efficacy and Safety of INC280 in Patients With Advanced Hepatocellular Carcinoma.

Advanced Hepatocellular Carcinoma With c-MET Dysregulation

China, Hong Kong, Thailand, Singapore
University of California, San Francisco

Completed

A Study of Oxidative Pathways in MS Fatigue

Progressive Multiple Sclerosis | Fatigue

United States
Sykehuset i Vestfold HF
Hospital Pharmacy Enterprise, South Eastern Norway

Completed

Patient Pathway Pharmacist - Optimal Drug-related Care

Aging | Hip Fractures | Patient Fall

Norway
Air Liquide Santé International

Completed

Study Evaluating Telemonitoring and Experimentation in Telemedicine for the Improvement of Healthcare Pathways (ETAPES Program) Compared to Standard of Care in Patients With Chronic Respiratory Failure Receiving Non-invasive Home Ventilation (e-VENT)

Chronic Obstructive Pulmonary Disease (COPD) | Obesity Hypoventilation Syndrome (OHS) | Chronic Respiratory Failure With Hypercapnia

France
University of Calgary
Alberta Health services

Completed

Treatment of Hypoxemic Respiratory Failure and ARDS With Protection, Paralysis, and Proning (TheraPPP) Pathway (TheraPPP)

Acute Respiratory Distress Syndrome | ARDS, Human | Hypoxemic Respiratory Failure

Canada
University of Pecs

Completed

Intracardiac Echocardiography Guided vs. Electroanatomical Mapping System Guided Slow Pathway Ablation in Patients With Atrioventricular Nodal Reentrant Tachycardia

Heart Rhythm Disorder

Hungary
University Hospital, Toulouse

Active, not recruiting

Interest of a Specific Care Pathway for the Management of Catamenial Epilepsy (EPICAT)

Epilepsy Menstrual

France
Memorial Sloan Kettering Cancer Center
Weill Medical College of Cornell University

Completed

MRI and Diffusion Imaging of Eloquent Brain Areas to Optimize Brain Tumor Resection Planning

Brain Cancer

United States
Basilea Pharmaceutica
ArQule, Inc. (a wholly owned subsidiary of Merck Sharp and Dohme, a subsidiary...

Completed

Phase 1/2 Study of Derazantinib (ARQ 087) in Adult Subjects With Advanced Solid Tumors With FGFR Genetic Alterations

Solid Tumor

United States, Italy
University of Nottingham
Versus Arthritis

Completed

Molecular Pathways Involved in Knee Pain

Knee Osteoarthritis | Knee Pain Chronic

United Kingdom
Peking University
Peking Union Medical College Hospital; First Affiliated Hospital, Sun Yat-Sen... and other collaborators

Completed

Multicenter Registry Study of Chronic Hypoparathyroidism in Chinese Adults (PaTHwayR)

Chronic Hypoparathyroidism

China
University College, London
University of Luebeck; Leiden University Medical Center; European Commission; University...

Completed

A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular "Powerhouse") Dysfunction (SysMedPD)

Parkinson Disease | Parkinsonism

United Kingdom
University of Sao Paulo General Hospital
InCor Heart Institute

Completed

Cryotherapy Versus Radiofrequency Ablation for Treatment of Para-hisian Accessory Pathways

Cardiac Arrhythmias | Accessory Pathway | Wolf Parkinson White Syndrome

Brazil
University Hospital, Antwerp

Completed

Multidisciplinary Perioperative Care Pathway in Adolescents Undergoing Posterior Spinal Fusion Surgery

Postoperative Pain | Analgesia | Surgery | Scoliosis Idiopathic

Belgium
University of Bern

Completed

Comparison of Two Implant Prosthetic Pathways

Failure of Dental Prosthesis
University of Vienna
Medical University of Vienna; Flinders University; Queensland University of Technology and other collaborators

Completed

Dietary Nitrate, Vascular Function and Inflammation

Inflammation | Hypertension

Austria
Aberystwyth University

Withdrawn

Comparing Frailty Care Pathways in Rural Primary Care: a Feasibility Study

Frailty

United Kingdom
Centre Hospitalier Universitaire de Saint Etienne
Institut de Cancérologie de la Loire; Centre Hospitalier Emile Roux; Hôpital... and other collaborators

Completed

Influence of PARAmedical Interventions on Patient ACTivation in the Cancer Care Pathway (PARACT)

Cancer

France
Denver Health and Hospital Authority
Denver Health Medical Center

Completed

Expert-Guided Early Tracheostomy Pathway

Respiratory Failure | Tracheostomy Complication

Jordan
University of Minnesota

Completed

Preparing Heart and Mind™: A Patient Engagement Pathway for Parents and Their Caregiving Partners After a Major Fetal Anomaly Diagnosis

Parent Mental Health

United States
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Characterization of Bile Acid Pathway in Obesity

Obesity

United States
Prisma Health-Midlands

Completed

Opiate Free Multimodal Pain Pathway in Elective Foot and Ankle Surgery: A Prospective Study

Ankle Fractures | Bunion of Unspecified Foot | Bunionette of Unspecified Foot | Hammertoe | Achilles Tendon Surgery

United States
University of Florida
Janssen, LP

Completed

Switching From DAPT to Dual Pathway Inhibition With Low-dose Rivaroxaban in Adjunct to Aspirin in Patients With Coronary Artery Disease (SWAP-AC)

Coronary Artery Disease

United States
University of Pennsylvania

Completed

Enhanced Recovery After Spine Surgery Randomized Clinical Trial (ERASS)

ERAS

United States
Tanta University

Completed

Role of Nitazoxanide and Escitalopram in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Egypt
COMPASS Pathways

Completed

The Safety and Efficacy of Psilocybin in Participants With Treatment Resistant Depression (P-TRD)

Treatment Resistant Depression

United States, Netherlands, Ireland, Germany, United Kingdom, Canada, Czechia, Denmark, Portugal, Spain
Haihe Biopharma Co., Ltd.

Terminated

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of HH2710 in Patient With Advanced Tumors

Melanoma | Erdheim-Chester Disease | Non-Small-Cell Lung Cancer | Advanced Tumors | Other RAS/RAF/MEK/ERK Mutated Tumors

United States, China
Nektar Therapeutics
Bristol-Myers Squibb

Terminated

A Study of Bempegaldesleukin (NKTR-214: BEMPEG) in Combination With Nivolumab Compared With the Investigator's Choice of a Tyrosine Kinase Inhibitor (TKI) Therapy (Either Sunitinib or Cabozantinib Monotherapy) for Advanced Metastatic Renal Cell Carcinoma (RCC)

Renal Cell Carcinoma | Metastatic Renal Cell Carcinoma

United States, Argentina, Brazil, Australia, Singapore, New Zealand, Russian Federation, Mexico, Peru, Chile
Roswell Park Cancer Institute
Pfizer

Completed

Breast Cancer Pathways Program Impact on Patient Shared Decision Making and Experience in Academic and Community Practice

Breast Carcinoma | Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Recurrent Breast Carcinoma | Metastatic Breast Carcinoma

United States
Medical University of Bialystok

Completed

Analysis of Parameters Indicating the Intensity of Suicidal Behavior in Psychiatric Patients

Cognitive Functions Confusion | Suicidal Behaviour
Nantes University Hospital

Completed

Study on the Prevalence of Hepatitis C In a psychiatRic Population (SaPHIR)

Hepatitis C

France
National Cancer Centre, Singapore
Novartis

Completed

A Trial of Gefitinib in Combination With BKM120 in Patients With Advanced Non-Small Cell Lung Cancer, With Enrichment for Patients Whose Tumours Harbour Molecular Alterations of PI3K Pathway and Known to Overexpress EGFR (BKM120)

Non-Small Cell Lung Cancer | Solid Tumors

Singapore
National Cancer Institute (NCI)

Completed

M7824 in Subjects With HPV Associated Malignancies

Cervical Cancer | Anal Cancer | Oropharyngeal Cancer | Human Papilloma Virus | Vaginal or Penile Cancer

United States
National Cancer Institute, Naples

Active, not recruiting

Pathway to Diagnosis of Ovarian Cancer (MITO-12)

Ovarian Cancer

Italy, Belgium, Germany

Search clinical trials for: Notch Pathway

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