Search clinical trials for: calcineurin inhibitors

Total 64334 results

Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Terminated

Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant and Cyclophosphamide, Mycophenolate Mofetil, Tacrolimus, and Sirolimus in Treating Patients With Primary Immunodeficiency Disorders or Noncancerous Inherited Disorders

Genetic Disorder | Severe Aplastic Anemia | Immunodeficiency Syndrome

United States
Andrew B Adams
Bristol-Myers Squibb

Completed

Belatacept Therapy for the Failing Renal Allograft (IM103-133)

Failing Renal Allograft

United States
University of Catania

Completed

Study on Treatment for Patients With Symptomatic Oral Lichen Planus

Lichen Planus, Oral

Italy
Alexandria University

Completed

Topical Cyclosporine A for the Treatment of Dry Eye: A Randomized Clinical Study

Dry Eye
Methodist Healthcare

Completed

Envarsus XL Immunosuppression Following Liver Transplantation

Recipients of Liver Transplant

United States
Assiut University

Unknown

Topical Immuonosuppressant Drugs in Spring Catarrh

Vernal Keratoconjunctivitis

Egypt
Albert Einstein Healthcare Network
Veloxis Pharmaceuticals

Active, not recruiting

Evaluate the Clinical Benefits of EnvarsusXR in Post Liver Transplant

Post Liver Transplant

United States
Leiden University Medical Center
Aurinia Pharmaceuticals Inc.

Unknown

Anti-Viral Effects of Voclosporin in COVID-19 Positive Kidney Transplant Recipients (VOCOVID)

Covid19 | Kidney Transplant Infection

Netherlands
Edoardo Melilli

Completed

Everolimus and Tacrolimus Combination for Regression of Left Ventricular Hypertrophy in Renal Transplants (ENHVIE)

Hypertrophy, Left Ventricular

Spain
NURIA LLOBERAS BLANCH

Completed

OPTImization of the Dose of tacroliMUS by Bayesian Prediction (OPTIMUS)

KIDNEY TRANSPLANTATION

Spain
Bristol-Myers Squibb

Completed

A Study in Maintenance Kidney Transplant Recipients Following Conversion to Nulojix® (Belatacept)-Based

Kidney Transplantation

Germany, United States, Colombia, Austria, Netherlands, France, Switzerland, Argentina, Norway, Sweden
Chong Kun Dang Pharmaceutical

Completed

Study to Evaluate the Efficacy and Safety of Once-Daily Tacrolimus in Kidney Transplant Recipients (OPIRUS)

Kidney Transplant

Korea, Republic of
BioLineRx, Ltd.

Completed

Phase IIA Open Label Study to Evaluate Efficacy and Safety of BL-8040 Followed by (hATG), Cyclosporine and Methyprednisolone in Adult Subjects With Aplastic Anemia or Hypoplastic Myelodysplastic Syndrome

Aplastic Anemia | Hypoplastic Myelodysplastic Syndrome

United States
Novartis Pharmaceuticals

Completed

Efficacy, Safety, Tolerability, and Pharmacokinetics of Sotrastaurin Combined With Tacrolimus vs. a Mycophenolic Acid-tacrolimus Regimen in Renal Transplant Patients

Renal Transplantation

United States, Germany, United Kingdom, Belgium, Australia, Hungary, Netherlands, Sweden, Colombia, Argentina, Brazil, Canada, Denmark, Korea, Republic of, Portugal
Novartis Pharmaceuticals

Completed

Efficacy, Safety, Tolerability, Pharmacokinetics of Sotrastaurin-tacrolimus vs. Mycophenolic Acid-tacrolimus in de Novo Liver Transplant Patients

Liver Transplantation

Belgium, Germany, Italy, United States, Switzerland, Spain, Austria, Czechia, France, Argentina, Finland, Canada
Novartis Pharmaceuticals

Terminated

24 Month Extension to Efficacy and Safety of AEB071 Plus Tacrolimus (Converted to Mycophenolic Acid After 3 Months) in Renal Transplant Patients(Converted to Mycophenolic Acid After 3 Months) in Renal Transplant Patients

Kidney Transplantation

Spain, Germany, Switzerland, Italy, United Kingdom, France, United States, Canada
National Institute of Allergy and Infectious Diseases...
Clinical Trials in Organ Transplantation

Terminated

Open-Label Phase 2 Trial of a Steroid-Free, CNI-Free, Belatacept-Based Immunosuppressive Regimen

Kidney Transplantation | Primary Renal Allograft Candidate

United States
University of Minnesota
Wyeth is now a wholly owned subsidiary of Pfizer; Roche Pharma AG; Genzyme, a...

Completed

Calcineurin Inhibitor Sparing After Kidney Transplantation (CNI-Sparing)

CNI Side Effects

United States
The Methodist Hospital Research Institute
Veloxis Pharmaceuticals

Withdrawn

Evaluation of Anti-rejection Drug, Tacrolimus, in African-Americans With Kidney Transplant

Acute Rejection of Renal Transplant | Kidney Disease, End-Stage | Donor Specific Antibodies
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Intra-Osseous Co-Transplant of UCB and hMSC

Myelodysplastic Syndromes | Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Myelofibrosis | Acute Lymphoblastic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Refractory Chronic Lymphocytic Leukemia | Refractory Non-Hodgkin Lymphoma | Lymphoid Malignancies | Relapsed Non-Hodgkin Lymphoma and other conditions

United States
University of Colorado, Denver

Terminated

Immunosuppressant Medication Dosed Daily After Kidney Transplant

Medication Adherence | Kidney Transplant Rejection

United States
OHSU Knight Cancer Institute
Oregon Health and Science University

Completed

Combination Chemotherapy and Donor Stem Cell Transplant Followed by Ixazomib Citrate Maintenance Therapy in Treating Patients With Relapsed High-Risk Multiple Myeloma

Recurrent Plasma Cell Myeloma | Plasma Cell Leukemia

United States
Dartmouth-Hitchcock Medical Center

Completed

Chemotherapy Followed by Allogeneic Stem Cell Transplantation for Hematologic Malignancies

Hematologic Malignancies

United States
Assistance Publique - Hôpitaux de Paris

Completed

Cyclophosphamide Versus Anti-thymocyte Globulin for GVHD Prophylaxis After RIC Allo-SCT (ATG-CyGVHD)

Graft vs Host Disease

France
Singapore Eye Research Institute

Unknown

Ikervis for DED Due to GVHD Post Allo-HSCT (Ikervis)

Leukemia (Both ALL and AML) | MDS-EB-1

Singapore
Hanlim Pharm. Co., Ltd.

Unknown

The Study of Pharmacokinetic Interactions Between HL237 and Tacrolimus

Healthy Male Volunteers

Korea, Republic of
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Itacitinib for the Prevention of Graft Versus Host Disease in Patients Undergoing Donor Stem Cell Transplantation

Hematopoietic and Lymphoid Cell Neoplasm | Hematologic and Lymphocytic Disorder | Allogeneic Stem Cell Transplant Recipient

United States
University of Colorado, Denver
Veloxis Pharmaceuticals

Terminated

Pilot Study of Treatment for Subclinical AMR (Antibody-mediated Rejection) in Kidney Transplant Recipients

Kidney Transplant Rejection

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy, Total Body Irradiation, and Donor Blood Stem Cell Transplant in Treating Patients With Primary or Secondary Myelofibrosis

Primary Myelofibrosis | Secondary Myelofibrosis

United States
Tampere University Hospital

Completed

Long-term Outcome of Patients With Acute Ulcerative Colitis After First Course of Intravenous Corticosteroids

Ulcerative Colitis
M.D. Anderson Cancer Center

Completed

Natural Killer (NK) Cell Adback After Allogeneic Stem Cell Transplant With Campath-IH Plus Chemorx for Patients With Lymphoid Malignancies

Lymphoma | Leukemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cyclosporine Inhalation Solution (CIS) in Lung Transplant and Hematopoietic Stem Cell Transplant Recipients for the Treatment of Bronchiolitis Obliterans Syndrome

Bronchiolitis Obliterans | Graft vs Host Disease | Constrictive Bronchiolitis | Bronchiolitis, Exudative | Bronchiolitis, Proliferative

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Comparing Therapies for the Treatment of Severe Aplastic Anemia

Severe Aplastic Anemia (SAA)

United States
Federal University of São Paulo
Allergan

Completed

Safety Study of the Use of Topical Cyclosporine in the Treatment of Dry Eye Disease

Evaporative Dry Eye Disease | Primary Sjogren Syndrome | Secondary Sjogren Syndrome | Aqueous Deficient Dry Eye Disease

Brazil
National Institute of Allergy and Infectious Diseases...
Rho Federal Systems Division, Inc.

Terminated

Donor-Alloantigen-Reactive Regulatory T Cell (darTregs) in Liver Transplantation (deLTa)

Liver Transplantation

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Extension Study (Extended Access) of Cyclosporine Inhalation Solution (CIS) in Lung Transplant and Hematopoietic Stem Cell Transplant Recipients for the Treatment of Bronchiolitis Obliterans

Bronchiolitis Obliterans | Graft Versus Host Disease | Graft-Versus-Host Disease | Constructive Bronchiolitis | Bronchiolitis, Exudative | Bronchiolitis, Proliferative

United States
Masonic Cancer Center, University of Minnesota

Completed

Myeloablative Umbilical Cord Blood Transplantation in Hematological Diseases

Lymphoma | Acute Myeloid Leukemia | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma | Non-Hodgkin's Lymphoma | Myelofibrosis | Chronic Lymphocytic Leukemia | Acute Lymphocytic Leukemia | MDS | Chronic Myelogenous Leukemia | Prolymphocytic Leukemia | Refractory Anemia

United States
Instituto de Seguridad y Servicios Sociales de...

Unknown

Cyclosporine A Plus Low-steroid Treatment in COVID-19 Pneumonia

COVID 19 Pneumonia

Mexico
Medical College of Wisconsin
Takeda

Terminated

Vedolizumab Monotherapy Vs Combination Therapy With Tacrolimus in UC (COVET)

Ulcerative Colitis

United States
Assistance Publique - Hôpitaux de Paris
Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Unknown

Pharmacokinetic of Tacrolimus in Paediatric Liver Transplant Patients (TACTHEP)

Liver Transplantation, Child

France
National Institute of Allergy and Infectious Diseases...
National Heart, Lung, and Blood Institute (NHLBI); Genentech, Inc.; Rho Federal... and other collaborators

Terminated

Prevention of Cardiac Allograft Vasculopathy Using Rituximab (Rituxan) Therapy in Cardiac Transplantation

Cardiac Allograft Vasculopathy | Heart Transplant Recipients

United States
Celgene

Completed

Drug Interaction Study of the Effect on Cyclosporine on Ozanimod and Major Active Metabolites

Healthy Volunteers

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

Selective Depletion of CD45RA+T Cells From Allogeneic Peripheral Blood Stem Cell Grafts for the Prevention of GVHD

Myelodysplastic Syndromes | Leukemia | Graft Versus Host Disease

United States
Mayo Clinic

Completed

Use of Sublingual Tacrolimus in Adult Blood and Marrow Transplant Patients

Stem Cell Transplant | Immunosuppression | Bone Marrow Transplant

United States
Astellas Pharma Global Development, Inc.

Completed

To Compare the Effects of Immediate-release Tacrolimus and Astagraf XL on Donor-Specific Antibody (DSA) Formation and the Development of Immune Activation (IA) in de Novo Kidney Transplant Recipients (ASTOUND)

Kidney Transplantation

United States
Jonsson Comprehensive Cancer Center

Withdrawn

Donor Lymphocytes to Prevent Graft-Versus-Host Disease in Patients With Chronic Myeloid Leukemia

Leukemia | Graft Versus Host Disease
Chiesi Farmaceutici S.p.A.

Completed

Pharmacokinetic Study of ENVARSUS in Adult De-novo Kidney Transplant Patients

Organ or Tissue Transplant; Complications

France
Novartis Pharmaceuticals

Completed

Nordic Everolimus (Certican) Trial in Heart and Lung Transplantation (NOCTET)

Disorder Related to Cardiac Transplantation

Denmark, Sweden, Norway
Case Comprehensive Cancer Center

Completed

Ultraviolet-B Light Therapy and Allogeneic Stem Cell Transplantation in Treating Patients With Hematologic Malignancies

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases

United States
Guy's and St Thomas' NHS Foundation Trust
Astellas Pharma Europe Ltd.

Unknown

RituxiMab INDuction in Renal Transplantation (ReMIND)

Function of Renal Transplant

United Kingdom

Search clinical trials for: calcineurin inhibitors

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