Search clinical trials for: cholesterol absorption inhibitor

Total 70223 results

Shiraz University of Medical Sciences

Completed

Is Sheep Ghee Cardioprotective?

Inflammation | Cholesterol; Metabolic Disorder

Iran, Islamic Republic of
National Taiwan University Hospital

Completed

Simvastatin Therapy in Patients With Dilated Cardiomyopathy. (SavDCM)

Dilated Cardiomyopathy

Taiwan
British University In Egypt

Completed

PLGA Nanoparticles Entrapping Ciprofloxacin to Treat E-Fecalis Infections in Endodontics

Bacterial Infections Oral

Egypt
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Pharmacokinetic Interaction Study Between Apatinib and Rosuvastatin or Metformin in Solid Tumor Subjects.

Solid Tumor, Adult

China
Pfizer

Completed

STUDY TO EVALUATE THE EFFECT OF PF-06882961 ON SINGLE DOSE ATORVASTATIN, MEDAZOLAM AND ORALCONTRACEPTIVE PHARMACOKINETICS IN HEALTHY ADULT PARTICIPANTS

Healthy Adults

United States
Amgen

Completed

Durable Effect of PCSK9 Antibody CompARed wiTh placEbo Study (DESCARTES)

Hypercholesterolemia

United States, Denmark, Belgium, Czechia, Austria, Australia, Canada, Hungary, South Africa
University of Cologne
German Federal Ministry of Education and Research

Completed

Statin Recapture Therapy Before Coronary Artery Bypass Grafting (StaRT-CABG)

Coronary Artery Disease

Germany
University of Southern Denmark

Completed

The Effect of Dicloxacillin on Oral Absorption of Drugs

Healthy Volunteers | Drug-drug Interaction

Denmark
Bioksan
Analysis and Research Network, S.L

Completed

Clinical Trial to Demonstrate the Efficacy of a Dietary Supplement in Decreasing Cardiovascular Risk

Low-Moderate Hypercholesterolemia

Spain
AHS Cancer Control Alberta
Ozmosis Research Inc.

Completed

Rosuvastatin in the Treatment of Rectal Cancer

Rectal Cancer

Canada
Addpharma Inc.

Completed

A Study to Evaluate the Efficacy and Safety of AD-221 and AD-221A

Primary Hypercholesterolemia

Korea, Republic of
Health Clinics Limited

Withdrawn

Study of the Safety, Tolerability and Efficacy of Metabolic Combination Treatments on Cancer (METRICS)

Cancer | Overall Survival

United Kingdom
Korea Otsuka Pharmaceutical Co., Ltd.

Completed

Evaluation of Concomitant Administration of Cilostazol and Probucol on Biomarkers, Endothelial Function and Safety

Peripheral Artery Disease

Korea, Republic of
Cumberland Pharmaceuticals

Completed

Dose-ranging Efficacy and Pharmacokinetics Study of Intravenous Atorvastatin in Hypercholesterolemic Patients

Dyslipidemias | Hypercholesterolemia

United States
Cedars-Sinai Medical Center
Synthetic Biologics Inc.

Terminated

Efficacy and Safety of SYN-010 in IBS-C

Irritable Bowel Syndrome With Constipation

United States
University College, London
London School of Hygiene and Tropical Medicine; The Leeds Teaching Hospitals... and other collaborators

Active, not recruiting

Multiple Sclerosis-Simvastatin Trial 2 (MS-STAT2)

Secondary Progressive Multiple Sclerosis (SPMS)

United Kingdom
Assiut University

Completed

Could Early Atorvastatin Offer Anti Inflammatory Effects Upon Brain in Traumatic Head Injury?

Traumatic Brain Injury

Egypt
Janssen Research & Development, LLC

Completed

A Study of Lazertinib (JNJ-73841937) in Healthy Participants

Healthy

United States
Sanofi

Completed

A Study to Evaluate the Efficacy and the Safety of Single Pill Combination (SPC) Ezetimibe/Rosuvastatin in Chinese Adult Patients With Primary Hypercholesterolemia Not Adequately Controlled on Statin Therapy (ROZEL)

Hypercholesterolemia

China
Gilead Sciences
Galapagos NV

Completed

Study to Evaluate Organic Anion Transporting Polypeptide (OATP) Transporter-Mediated Drug-Drug Interactions Between Filgotinib and Statins as Probe Drugs in Healthy Participants

Rheumatoid Arthritis

United States
University of Washington
National Heart, Lung, and Blood Institute (NHLBI); Pfizer; Daiichi Sankyo, Inc.; Abbo... and other collaborators

Completed

Evaluate Carotid Artery Plaque Composition by Magnetic Resonance Imaging in People Receiving Cholesterol Medication (CPC)

Coronary Artery Disease | Atherosclerosis | Carotid Artery Diseases

United States
VA Office of Research and Development

Terminated

Ezetimibe as a Safe and Efficacious Treatment for Chronic Hepatitis C

Chronic Hepatitis C

United States
Fundación de investigación HM
Apices Soluciones S.L.

Completed

Study of Ruxolitinib Plus Simvastatin in the Prevention and Treatment of Respiratory Failure of COVID-19. (Ruxo-Sim-20)

Coronavirus Infection

Spain
University Health Network, Toronto

Terminated

Eliminate Coronary Artery Disease (ECAD)

Coronary Artery Disease

Canada
Wuhan Union Hospital, China

Enrolling by invitation

An Experimental Study on the Effect of Tenofovir Amibufenamide on Blood Lipid During Anti-HBV Treatment

Hepatitis B, Chronic | Lipid Disorder

China
Takeda
Ovid Therapeutics Inc.

Completed

A Multicenter, Open-label, Pilot Study of Soticlestat (TAK-935/OV935) in Participants With 15Q Duplication Syndrome (Dup 15q) or Cyclin-Dependent Kinase-Like 5 (CDKL5) Deficiency Disorder (ARCADE STUDY)

15q Duplication Syndrome | CDKL5 Deficiency Disease

United States
Kadmon Corporation, LLC
Quotient Sciences

Completed

Human Absorption, Distribution and Metabolism Study (hAME) [14C]-KD025 (KD025-108)

Fibrosis | Autoimmune Diseases

United Kingdom
Actelion

Completed

A 2-part Study to Investigate the Effect of Macitentan in Healthy Male Participants

Healthy

Belgium
Dr. med. Mahir Karakas

Terminated

Effect of Platelet Inhibition and / or Lipid Lowering in Non-ACS-patients With Positive Troponin (GRAY-ZONE)

Acute Chest Syndrome

Germany
Orient Pharma Co., Ltd.

Completed

Compare the Efficacy and Safety of 1PC111 With Pitavastatin and Ezetimibe in Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia

Primary Hypercholesterolemia | Mixed Dyslipidemias

Taiwan, Australia, New Zealand
Postgraduate Medical Institute, Lahore

Completed

Salivary Bmp-2 Levels & Radiographic Measurement Of Bone Density at Extracted Tooth (salivaryBMP2)

Bone Injury

Pakistan
HK inno.N Corporation

Completed

Evaluate Efficacy and Safety of Ezetimibe/Rosuvastatin and Candesartan Cilexetil/Amlodipine Besylate Combination Tablets (REVERT-K)

Hypertension, Hyperlipidemia

Korea, Republic of
AstraZeneca
Parexel

Completed

Study to Assess the Effect of Food and Acid Reducing Agents on the Absorption of Capivasertib in Healthy Participants

Solid and Hematological Malignancies

Germany
Amarin Pharma Inc.

Completed

Efficacy and Safety of AMR101 (Ethyl Icosapentate) in Patients With Fasting Triglyceride (Tg) Levels ≥ 500 and ≤ 2000 mg/dL (MARINE)

Hypertriglyceridemia

United States, Netherlands, Russian Federation, Ukraine, Denmark, Finland, Germany, India, Italy, Mexico, South Africa
Amarin Pharma Inc.

Completed

Effect of AMR101 (Ethyl Icosapentate) on Triglyceride (Tg) Levels in Patients on Statins With High Tg Levels (≥ 200 and < 500 mg/dL) (ANCHOR)

Hypertriglyceridemia

United States
Aurinia Pharmaceuticals Inc.

Completed

Drug-Drug Interaction Study to Investigate Effects of Voclosporin on Pharmacokinetics of Simvastatin (Statin-DDI)

Drug-drug Interaction

United States
Overseas Pharmaceuticals, Ltd.

Completed

To Evaluate the Food Effect and the Absorption Profile of Ibuprofen Modified-Release Tablets 800 mg

Chronic Pain

China
Alexandria University

Completed

Atorvastatin Effects On Arterial Stiffness In Hemodialysis

Arterial Stiffness

Egypt
Loxo Oncology, Inc.
Eli Lilly and Company

Completed

A Drug Drug Interaction (DDI) Study of Pirtobrutinib (LY3527727) and Rosuvastatin in Healthy Participants

Healthy

United States
Amarin Pharma Inc.

Completed

A Study of AMR101 to Evaluate Its Ability to Reduce Cardiovascular Events in High-Risk Patients With Hypertriglyceridemia and on Statin (REDUCE-IT)

Cardiovascular Diseases

United States, Australia, Canada, India, Netherlands, New Zealand, Poland, Romania, Russian Federation, South Africa, Ukraine
Sanofi

Completed

Evaluation of the Fixed-dose Combination of Irbesartan/Atorvastatin in Type 2 Diabetic Patients Diagnosed With Hyperlipidemia and Hypertension

Type 2 Diabetes Mellitus

Korea, Republic of
JW Pharmaceutical

Completed

Efficacy and Safety Study of Pitavastatin Versus Atorvastatin to Treat Hypercholesterolemia (PITCH)

Hypercholesterolemia
Rutgers, The State University of New Jersey

Completed

Evaluation of Micropore"s SpiraLith Absorbents

Airway Management During Operative Procedure

United States
All India Institute of Medical Sciences, Bhubaneswar
Coconut Development Board, Government of India

Completed

Effect of Virgin Coconut Oil (VCO) on Cardiometabolic Parameters in Patients With Dyslipidemia

Dyslipidemias

India
National Cancer Center, Korea
Boehringer Ingelheim

Completed

BIBW 2992 Plus Simvastatin vs. BIBW 2992 in Previously Treated Patients With Advanced Non-adenocarcinomatous NSCLC

Non-small Cell Lung Cancer

Korea, Republic of
National Cancer Center, Korea

Active, not recruiting

Irinotecan/Cisplatin With or Without Simvastatin in Chemo-naive Patients With Extensive Disease-small Cell Lung Cancer

Small Cell Lung Carcinoma

Korea, Republic of
Overseas Pharmaceuticals, Ltd.
Virginia Contract Research Organization Co., Ltd.

Terminated

To Evaluate the Food Effect and the Absorption Profile of Ibuprofen Controlled-Release Tablets 600 mg in Comparison to the Reference Standard Ibuprofen Tablets in Normal Healthy Volunteers

Pain Control

Taiwan
Helwan University

Completed

Statins in Patients With Type 2 Diabetes Mellitus and Previous History of Acute Coronary Syndrome

Diabetes Mellitus | Hydroxymethylglutaryl-CoA Reductase Inhibitors

Egypt
Sanofi
Regeneron Pharmaceuticals

Completed

Safety, Tolerability, and Effect of Alirocumab in High Cardiovascular Risk Patients With Severe Hypercholesterolemia Not Adequately Controlled With Conventional Lipid-modifying Therapies (ODYSSEY APPRISE)

Hypercholesterolemia

France, Belgium, Austria, Canada, Czechia, Denmark, Finland, Germany, Greece, Hungary, Poland, Romania, Slovakia, Slovenia, Spain, Switzerland
Minneapolis Heart Institute Foundation

Active, not recruiting

The DEtermining Statin Intolerance FOr Rosuvastatin (DESIFOR) Trial (DESIFOR)

Cardiovascular Diseases | Cardiovascular Risk Factor | Adverse Effect

United States

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