Search clinical trials for: Antineoplastic Protocols

Total 66107 results

National Center for Research Resources (NCRR)

Unknown

Thalidomide and Dacarbazine for Metastatic Melanoma

Melanoma

United States
Interferon Sciences

Completed

Double-Blind, Randomized, Placebo-Controlled Study of Low Dose Oral Interferon Alfa-n3 (Human Leukocyte Derived) in ARC Patients

HIV Infections

United States
National Center for Research Resources (NCRR)
Children's Hospital Colorado

Unknown

Phase I Study of Colchicine Therapy in Childhood Hepatic Cirrhosis

Liver Cirrhosis | Cirrhosis
National Center for Research Resources (NCRR)
University of California, Los Angeles

Completed

Phase II Study of Bone Marrow Transplantation Using Related Donors in Patients With Aplastic Anemia

Aplastic Anemia

United States
Cytran

Completed

Safety and Effectiveness of an Experimental Drug, IM862, in Treating Kaposi's Sarcoma in AIDS Patients

HIV Infections | Sarcoma, Kaposi

Canada, United States, Australia, Belgium
University of Minnesota

Completed

Phase I/II Study of Total Body Irradiation, Cyclophosphamide, and Fludarabine Followed by Alternate Donor Hematopoietic Cell Transplantation in Patients With Fanconi's Anemia

Fanconi's Anemia

United States
National Center for Research Resources (NCRR)
Crohn's and Colitis Foundation

Completed

A Pharmacokinetic Study to Determine the Oral Bioavailability of Methotrexate in Patients With Inflammatory Bowel Disease

Inflammatory Bowel Disease

United States
National Center for Research Resources (NCRR)
National Institute of Neurological Disorders and Stroke (NINDS); University...

Completed

Phase III Randomized, Double-Blind Study of Prednisone for Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy
National Center for Research Resources (NCRR)
Johns Hopkins University

Completed

Phase II Study of Sodium Phenylbutyrate, Sodium Benzoate, Sodium Phenylacetate, and Dietary Intervention for Urea Cycle Disorders

Amino Acid Metabolism, Inborn Errors
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

A Third-Party Blinded, Placebo Controlled Comparative Study of AS-101 Administered Intravenously in HIV Positive Patients With Advanced Disease

HIV Infections

Brazil
Light Sciences LLC

Completed

Photodynamic Therapy System for Patients With Refractory/Unresponsive Solid Tumors

Sarcoma | Breast Cancer | Head and Neck Cancer | Colorectal Cancer | Rectal Cancer | Pelvic Cancer | Mouth Cancer | Liver Metastasis

United States
R W Johnson Pharmaceutical Research Institute

Completed

A Double-Blind Study to Evaluate the Safety and Pharmacokinetics of L-Ofloxacin (RWJ 25213) in Subjects With HIV Infection

HIV Infections

United States
Fairview University Medical Center

Completed

Study of Allogeneic Bone Marrow Transplantation Using Matched, Related Donors in Patients With Nonmalignant Hematologic Disorders

Neutropenia | Sickle Cell Anemia | Red-Cell Aplasia, Pure | Thalassemia Major

United States
Sandoz

Completed

A Multicenter Placebo-Controlled Dose Titration Study to Evaluate the Efficacy and Safety of Sandostatin (SMS 201-995) in the Treatment of Patients With Acquired Immunodeficiency Related Diarrhea

HIV Infections | Diarrhea

United States
SUGEN

Completed

Safety and Effectiveness of Giving SU5416 to HIV-Infected Patients With AIDS-Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States
Rockefeller University

Completed

Immunomodulation of HIV-1 Infected Individuals With PEG-Interleukin-2

HIV Infections

United States
Sandoz

Completed

A Phase I/II Pilot Study of Simultaneously Administered Rhu GM-CSF ( CHO Cell ) and Azidothymidine ( AZT ) in Patients With Severe HIV Infection and Leukopenia: Pharmacokinetics and Feasibility

HIV Infections | Cytopenias

United States
Tularik

Terminated

T138067 Versus Doxorubicin in Chemotherapy-Naive, Unresectable, Hepatocellular Carcinoma Patients

Hepatocellular Carcinoma

United States, Russian Federation, United Kingdom, Singapore, Thailand, Ukraine, Brazil, China, Poland, Puerto Rico, South Africa
National Center for Research Resources (NCRR)
Ohio State University

Completed

Phase II Study of Leuprolide and Testosterone for Men With Kennedy's Disease or Other Motor Neuron Disease

Amyotrophic Lateral Sclerosis | Spinal Muscular Atrophy | Spinobulbar Muscular Atrophy
National Center for Research Resources (NCRR)
Tulane University School of Medicine

Completed

Phase III Randomized Study of High Vs Standard Dose of Interferon Alfa for Chronic Hepatitis C

Hepatitis C
Otsuka America Pharmaceutical

Completed

A Study of Multiple Doses of Vesnarinone in Advanced HIV Disease

HIV Infections

United States
National Center for Research Resources (NCRR)
Baylor College of Medicine

Completed

Phase II Study of the Effect of Leuprolide Acetate and Spironolactone on Insulin Resistance in Hyperandrogenic Women With Polycystic Ovarian Disease or Hyperandrogenism Insulin Resistance Acanthosis Nigricans Syndrome

Polycystic Ovary Syndrome | Acanthosis Nigricans
Daiichi Pharmaceuticals

Completed

A Phase I Trial of Tecogalan Sodium ( DS-4152 ) Administered as an Infusion Weekly x 4

HIV Infections | Sarcoma, Kaposi

United States
U.S. Bioscience

Completed

A Compassionate Treatment Protocol for the Use of Trimetrexate Glucuronate (Neutrexin) With Leucovorin Protection for European Adult Patients (>= 13 Years Old) With Pneumocystis Carinii Pneumonia

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Baker Norton Pharmaceuticals

Completed

Paclitaxel in Advanced Refractory Kaposi's Sarcoma (AIDS-KS): A Phase II Trial of Paclitaxel From Baker Norton Pharmaceuticals

HIV Infections | Sarcoma, Kaposi

United States
Fairview University Medical Center

Unknown

Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Giant Cell Arteritis | Wegener's Granulomatosis | Churg-Strauss Syndrome | Polyarteritis Nodosa | Purpura, Schoenlein-Henoch | Juvenile Rheumatoid Arthritis | Takayasu Arteritis | Pure Red Cell Aplasia | Graft Versus Host Disease | Anemia, Hemolytic, Autoimmune and other conditions

United States
Fairview University Medical Center

Unknown

Pilot Study of Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients With Life Threatening Hemophagocytic Disorders

Hemophagocytic Lymphohistiocytosis | Graft Versus Host Disease | Chediak-Higashi Syndrome | Virus-Associated Hemophagocytic Syndrome | X-Linked Lymphoproliferative Syndrome | Familial Erythrophagocytic Lymphohistiocytosis

United States
National Center for Research Resources (NCRR)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University...

Completed

Phase III Randomized Study of Ursodiol With Vs Without Methotrexate for Primary Biliary Cirrhosis

Liver Cirrhosis, Biliary
Aronex Pharmaceuticals

Unknown

A Safety and Effectiveness Study of Aroplatin in Patients With Advanced Solid Malignancies

Neoplasms | Colorectal Neoplasms | Hepatocellular Carcinoma | Pancreatic Neoplasms | Esophageal Neoplasms | Ovarian Neoplasms

United States
Genelabs Technologies

Completed

A Randomized Phase II Efficacy, Activity and Safety Study of GLQ223 Alone and in Combination With Zidovudine in Symptomatic HIV-Infected Patients Without Prior Treatment With GLQ223 or Trichosanthin

HIV Infections

United States
Schering-Plough

Completed

Phase III Ganciclovir +/- rGM-CSF for AIDS-Related CMV Retinitis

HIV Infections | Cytomegalovirus Retinitis

United States
Sandoz

Completed

A Multicenter Placebo-Controlled Double Blind Study to Evaluate the Efficacy and Safety of Sandostatin ( SMS 201-995 ) in Patients With Acquired Immunodeficiency Related Diarrhea Who Were Either "Responders" or "Non-Responders" in a Prior Placebo-Controlled Double-Blind Sandostatin Study.

HIV Infections | Diarrhea

United States
Lederle Laboratories

Completed

Phase II Study of Intravenous Novantrone(R) in the Treatment of AIDS Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States
Hoffmann-La Roche

Completed

A Study of Ro 24-7429 in Patients With HIV-Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi

United States
Triangle Pharmaceuticals

Completed

A Study of MKC-442 in Combination With Other Anti-HIV Drugs

HIV Infections

United States
Celgene Corporation

Completed

Compassionate Use Study of Two Dose Levels of Thalidomide in Adults With HIV Wasting Syndrome

HIV Infections | HIV Wasting Syndrome

United States
FeRx

Unknown

Safety and Efficacy of Doxorubicin Adsorbed to Magnetic Beads

Hepatocellular Carcinoma

China
Chiron Corporation

Completed

Safety and Efficacy of Polyethylene Glycolated IL-2 (PEG IL-2) Plus Zidovudine or Dideoxyinosine in HIV Positive, Asymptomatic and Symptomatic Individuals

HIV Infections

United States
Purdue Frederick
Walter Reed Army Institute of Research (WRAIR); Henry M. Jackson Foundation...

Completed

Phase I Study of Alferon N Injection in Persons With Asymptomatic Human Immunodeficiency Virus (HIV) Infection

HIV Infections

United States
Daiichi Pharmaceuticals

Completed

A Phase I Trial of Tecogalan Sodium ( DS-4152 ) Administered as an Infusion Twice Weekly for 21 Days.

HIV Infections | Sarcoma, Kaposi

United States
Anderson Clinical Research
Ligand Pharmaceuticals

Completed

A Study of ALRT1057 in Patients With AIDS-Related Kaposi's Sarcoma

HIV Infections | Sarcoma, Kaposi
Glaxo Wellcome

Completed

Safety and Effectiveness of a Combination Anti-HIV Drug Treatment

HIV Infections

United States
Fred Hutchinson Cancer Center

Completed

Phase I Pilot Study of Total-Body Irradiation, Anti-Thymocyte Globulin and Cyclophosphamide Followed By Syngeneic or Autologous Peripheral Blood Stem Cell Transplantation in Patients With Multiple Sclerosis

Multiple Sclerosis

United States
Corixa Corporation

Completed

Safety and Efficacy Study of Iodine-131 Anti-B1 Antibody Plus CHOP For Untreated Mantle Cell Lymphoma

Mantle Cell Lymphoma

United States
Millennium Pharmaceuticals, Inc.

Terminated

Phase I Dose Escalation Study of VELCADE Plus Docetaxel in Patients With Advanced Non-Small Cell Lung Cancer or Other Solid Tumors

Advanced Non-Small Cell Lung Cancer | Other Solid Tumors
Aronex Pharmaceuticals

Unknown

Aroplatin and Capecitabine in Patients With Advanced Colorectal Cancer Resistant to Standard Therapies

Colorectal Neoplasms
Celgene Corporation

Completed

A Study to Access the Safety/Efficacy of Thalidomide in the Treatment of Anemia in Patients With Myelodysplastic Syndromes

Myelodysplastic Syndromes

United States
National Center for Research Resources (NCRR)

Completed

Treatment of Hepatocellular Carcinoma With Tetrathiomolybdate

Carcinoma, Hepatocellular

United States
Corixa Corporation

Unknown

Safety and Efficacy of Iodine-131 Anti-B1 Antibody for Intermediate Grade Non-Hodgkin's Lymphoma Following First Line CHOP

Non-Hodgkin's Lymphoma

United States
National Center for Research Resources (NCRR)
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Phase III Randomized, Double-Blind, Placebo-Controlled Study of Antenatal Thyrotropin-Releasing Hormone in Pregnant Women With Threatened Premature Delivery

Respiratory Distress Syndrome

3

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