Search clinical trials for: Polymerase inhibitor

Total 68235 results

Wyeth is now a wholly owned subsidiary of Pfizer

Completed

An Open Parallel Study to Determine the Optimum Dosing Schedule for AS-101 in AIDS/ARC Patients

HIV Infections

United States
Gilead Sciences
Anderson Clinical Research

Unknown

A Study of Cidofovir in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis
Glaxo Wellcome

Completed

A Study of the Safety and Effectiveness of Different Doses of 1592U89 in HIV-Infected Patients

HIV Infections

France, Germany
U.S. Bioscience

Completed

A Study of Neutrexin Plus Leucovorin in the Treatment of Pneumocystis Carinii Pneumonia (PCP)

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Gilead Sciences

Unknown

The Safety of Tenofovir Disoproxil Fumarate Taken With Other Anti-HIV Drugs to Treat HIV-Infected Patients

HIV Infections

United States
Triangle Pharmaceuticals

Unknown

Emtricitabine Given Once A Day With Other Anti-HIV Drugs in Children With HIV

HIV Infections

United States, Argentina, Mexico, Panama, Puerto Rico, South Africa
Roche Global Development

Completed

An Open Label Evaluation of the Safety and Pharmacokinetics of Ganciclovir in Children

HIV Infections | Cytomegalovirus Retinitis

United States
University of California, San Francisco

Completed

A Randomized Controlled Prophylactic Study of Clofazimine To Prevent Mycobacterium Avium Complex Infection in HIV Disease

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
Pfizer

Completed

An Open, Non-Comparative Study of Intravenous and Oral Fluconazole in the Treatment of Acute Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States
Otsuka America Pharmaceutical

Completed

A Phase I Study of Three Doses of OPC-8212 (Vesnarinone) in HIV-Infected Persons With CD4+ Cell Number > 300 Cells/mm3

HIV Infections

United States
Hoffmann-La Roche

Completed

A Randomized, Parallel Arm, Comparative, Open Label, Multicenter Study of the Activity and Safety of Two Formulations of Saquinavir in Combination With Other Antiretroviral Drugs

HIV Infections

Canada, United States
Gilead Sciences

Unknown

Safety and Effectiveness of Adding Adefovir Dipivoxil and Nelfinavir to the Anti-HIV Therapy of HIV-Infected Children

HIV Infections

United States
Hoffmann-La Roche

Completed

A Study of Ganciclovir in the Treatment of Cytomegalovirus of the Large Intestine in Patients With AIDS

HIV Infections | Colitis

United States
Astra USA

Unknown

A Study of Foscarnet in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS Who Have Not Had Success With Ganciclovir

HIV Infections | Cytomegalovirus Retinitis

United States
Boehringer Ingelheim

Completed

The Safety and Effectiveness of Nevirapine and Zidovudine, Given Separately and Together, in HIV-1 Infected Patients Who Have No Symptoms of the Disease

HIV Infections

United States
Rockefeller University

Completed

A Study of Thalidomide in HIV-Infected Patients Who Are Receiving HAART

HIV Infections

United States
Pharmacia and Upjohn

Completed

A Study of Two Anti-HIV Drug Combinations in HIV-Infected Patients

HIV Infections

United States
Gilead Sciences

Completed

Safety and Effectiveness of Tenofovir Disoproxil Fumarate (Tenofovir DF) Plus Other Anti-HIV Drugs in HIV-Infected Patients

HIV Infections

United States, Puerto Rico
Celgene Corporation

Completed

Study to Compare the Efficacy and Safety of Two CC-5013 Dose Regimens in Subjects With Metastatic Malignant Melanoma

Melanoma | Neoplasm Metastasis

United States, Canada
Merck Sharp & Dohme LLC

Completed

A Multicenter, Open-Label, Randomized, 24-Week Study to Compare the Safety and Activity of Indinavir Sulfate, 800 Mg q 8 h Versus 1,200 Mg q 12 h in Combination With Zidovudine and 3TC

HIV Infections

United States
Triangle Pharmaceuticals

Unknown

A Comparison of Emtricitabine and Stavudine Used With Didanosine Plus Efavirenz in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs

HIV Infections

United States, Puerto Rico, Canada, Argentina, Chile, Mexico
Genentech, Inc.

Completed

Safety, Efficacy, and Pharmacokinetics Study of Tarceva to Treat Advanced Colorectal Cancer

Colorectal Cancer

United States
Wentworth Area Health Services
Abbott

Unknown

Levosimendan Versus Dobutamine in Shock Patients

Septic Shock | Cardiogenic Shock

Australia
Merck Sharp & Dohme LLC

Completed

The Safety and Effectiveness of Indinavir Sulfate Plus Efavirenz

HIV Infections

United States
Agouron Pharmaceuticals

Completed

A Study of Capravirine Plus VIRACEPT Plus Two Nucleoside Reverse Transcriptase Inhibitors in HIV-Infected Patients Who Failed Previous Anti-HIV Treatments

HIV Infections

United States
Astra USA

Completed

Phase III Multicenter, Open-Label, Randomized Trial of Induction Versus Induction Plus Maintenance Foscarnet ( Foscavir ) Therapy for Gastrointestinal CMV Disease

Gastrointestinal Diseases | HIV Infections

United States
Hoffmann-La Roche

Completed

Dideoxycytidine ( Ro 24-2027 ). A Treatment Protocol for the Use of Dideoxycytidine ( ddC ) in Patients With AIDS or Advanced ARC Who Cannot Be Maintained on Zidovudine ( AZT ) Therapy.

HIV Infections

United States
National Center for Research Resources (NCRR)
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Phase III Randomized, Controlled Study of Ganciclovir for Symptomatic Congenital Cytomegalovirus Infection

Cytomegalovirus Infections
Glaxo Wellcome

Completed

A Phase II Open Randomized Comparison of 566C80 and Pentamidine Isethionate for the Treatment of Pneumocystis Carinii Pneumonia in AIDS Patients Who Are Intolerant of Trimethoprim / Sulfamethoxazole

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Hoffmann-La Roche

Completed

Ganciclovir: Compassionate Use in Patients With Serious or Life-Threatening Cytomegalovirus Infections

HIV Infections | Cytomegalovirus Infections

United States
Agouron Pharmaceuticals

Suspended

Safety and Effectiveness of a New Anti-HIV Drug (AG1549) in Combination With Other Anti-HIV Drugs in HIV-Infected Patients

HIV Infections

United States, Dominican Republic
Pfizer

Completed

Open, Non-Comparative Study of Fluconazole in Patients With Coccidioidal Meningitis

HIV Infections | Meningitis

United States
Merck Sharp & Dohme LLC

Completed

A Study of L-735,524 in HIV-Positive Children and Adolescents

HIV Infections

United States
Hoffmann-La Roche

Completed

A Multiple Dose Crossover Pharmacokinetics Study to Evaluate the Effects of Food on the Absorption of Oral Ganciclovir

HIV Infections | Cytomegalovirus Infections

United States
Hoffmann-La Roche

Completed

A Randomized Study Comparing the Safety and Efficacy of Two Regimens of Oral Ganciclovir to Intravenous Ganciclovir Maintenance Therapy for Cytomegalovirus Retinitis in People With AIDS Who Have Received Prior Ganciclovir Therapy

HIV Infections | Cytomegalovirus Retinitis

United States, Canada
Roche Global Development

Completed

A Study of Two Forms of Ganciclovir in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States, Canada
University of Pittsburgh

Completed

The Effects of AZT and Ibuprofen on HIV-Infected Patients With Hemophilia

HIV Infections | Hemophilia A

United States
National Center for Research Resources (NCRR)
University of Texas

Unknown

Study of the Approximate Entropy of Adrenocorticotropic Hormone and Cortisol Secretion in Patients With Head Injury

Brain Injury | Craniocerebral Trauma

United States
University of Miami

Completed

A Pilot Study of the Efficacy of Recombinant Alpha Interferon (IFN-A2b) and Zidovudine (AZT) in the Treatment of Progressive Multifocal Leukoencephalopathy (PML) Complicating HIV-1 Infection

HIV Infections | Leukoencephalopathy, Progressive Multifocal

United States
Hoffmann-La Roche

Completed

A Phase I Pharmacokinetic Study in HIV-Positive Subjects of Oral Ganciclovir and Concomitant Antiretroviral Zidovudine and Didanosine

HIV Infections | Cytomegalovirus Infections

United States
Glaxo Wellcome

Unknown

Comparison of GW433908/Ritonavir to Nelfinavir When Used With Abacavir and Lamivudine in Patients That Have Not Taken Antiretroviral Drugs

HIV Infections

United States
Gilead Sciences

Completed

A Compassionate Use Study of Tenofovir Disoproxil Fumarate as Treatment for HIV Infection

HIV Infections

United States
Pfizer

Completed

A Study of Fluconazole in the Treatment of Cryptococcal Meningitis in Patients With AIDS

HIV Infections | Meningitis, Cryptococcal

United States
Hoffmann-La Roche

Completed

An Open-Label Safety Program for the Use of Zalcitabine (Dideoxycytidine; ddC) in Pediatric Patients With Symptomatic HIV Infection Who Have Failed or Are Intolerant to AZT Monotherapy, or Who Have Completed Other ddC Protocols, or Are Ineligible for Other Ongoing Clinical Studies

HIV Infections

United States
Agouron Pharmaceuticals

Unknown

Effectiveness of Treating HIV-Positive Patients With an HIV Vaccine (Remune)

HIV Infections

United States
Glaxo Wellcome

Completed

An Oral Dose-Ranging Finding Study in Patients With HIV Disease, CDC Classification Groups IIB, III, and IV-C2

HIV Infections

United States
Gilead Sciences

Completed

A Phase II, Stratified, Randomized, Double-Blind, Multi-Center Study of the Safety and Efficacy of Adefovir Dipivoxil (ADF) at Two Dose Levels in Triple Combination Therapies With Protease Inhibitors (PI) and Nucleoside Reverse Transcriptase Inhibitors (RTI) for the Treatment of HIV-Infected Patient

HIV Infections

United States, Puerto Rico
Hoffmann-La Roche

Completed

The Safety and Effectiveness of Two Forms of Saquinavir Combined With Other Anti-HIV Drugs in HIV-Infected Infants and Children

HIV Infections

United States
National Center for Research Resources (NCRR)
University of North Carolina

Completed

Study of the Pharmacokinetics of Mycophenolate Mofetil in Patients Who Have Undergone Orthotopic Liver Transplantation

Graft Versus Host Disease

United States
Glaxo Wellcome

Completed

An Open-Label, Uncontrolled Clinical Trial of Oral 566C80 for the Treatment of Patients With Severe PCP Who Are Intolerant and/or Unresponsive to Therapy With Trimethoprim/Sulfamethoxazole and Parenteral Pentamidine

HIV Infections | Pneumonia, Pneumocystis Carinii

United States

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